ZA892720B - Amino acid derivatives - Google Patents

Amino acid derivatives

Info

Publication number
ZA892720B
ZA892720B ZA892720A ZA892720A ZA892720B ZA 892720 B ZA892720 B ZA 892720B ZA 892720 A ZA892720 A ZA 892720A ZA 892720 A ZA892720 A ZA 892720A ZA 892720 B ZA892720 B ZA 892720B
Authority
ZA
South Africa
Prior art keywords
amino acid
acid derivatives
derivatives
amino
acid
Prior art date
Application number
ZA892720A
Other languages
English (en)
Inventor
Peter Raddatz
Raddatz Peter
Joachim Gante
Gante Joachim
Johannes Sombroek
Sombroek Johannes
Claus J Schmitges
J Schmitges Claus
Klaus-Otto Minck
Minck Klaus-Otto
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of ZA892720B publication Critical patent/ZA892720B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA892720A 1988-04-14 1989-04-13 Amino acid derivatives ZA892720B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3812328A DE3812328A1 (de) 1988-04-14 1988-04-14 Aminosaeurederivate

Publications (1)

Publication Number Publication Date
ZA892720B true ZA892720B (en) 1989-12-27

Family

ID=6351910

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA892720A ZA892720B (en) 1988-04-14 1989-04-13 Amino acid derivatives

Country Status (12)

Country Link
EP (1) EP0337334A3 (ja)
JP (1) JPH026449A (ja)
KR (1) KR890016062A (ja)
CN (1) CN1037155A (ja)
AU (1) AU618335B2 (ja)
DE (1) DE3812328A1 (ja)
DK (1) DK177789A (ja)
FI (1) FI891761A (ja)
HU (1) HU206888B (ja)
NZ (1) NZ228707A (ja)
PT (1) PT90273B (ja)
ZA (1) ZA892720B (ja)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3717631A1 (de) * 1987-05-26 1988-12-15 Merck Patent Gmbh Aminosaeurederivate
CA2066644A1 (en) * 1989-10-27 1991-04-28 Robert L. Heinrikson Method for treating hiv and other retroviruses and compounds useful therefor
TW209870B (ja) * 1990-01-18 1993-07-21 Pfizer
EP0483403A1 (en) * 1990-10-31 1992-05-06 Hoechst Aktiengesellschaft Derivatives of amino acids as inhibitors of renin, methods for their preparation, medicaments containing them and their use
US5442044A (en) * 1991-01-04 1995-08-15 Pfizer Inc. Orally active renin inhibitors
EP0610431A1 (en) * 1991-11-01 1994-08-17 Smithkline Beecham Corporation Hiv protease inhibitors containing guanidine
EP2673287B1 (de) 2011-02-08 2017-08-30 Merck Patent GmbH Aminostatin-derivate zur behandlung von arthrose
US9624264B2 (en) 2012-07-24 2017-04-18 Merck Patent Gmbh Hydroxystatin derivatives for the treatment of arthrosis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL81234A (en) * 1986-01-16 1992-09-06 Abbott Lab Peptidylaminodiols,process for their preparation and pharmaceutical compositions comprising them
DE3601248A1 (de) * 1986-01-17 1987-07-23 Hoechst Ag Substituierte 4-amino-3-hydroxybuttersaeure-derivate, verfahren zu deren herstellung, diese enthaltende mittel und ihre verwendung
ES2066755T3 (es) * 1986-06-10 1995-03-16 Merck Patent Gmbh Derivados de aminoacidos inhibidores de renina.
DE3721855A1 (de) * 1987-03-12 1988-09-22 Merck Patent Gmbh Aminosaeurederivate

Also Published As

Publication number Publication date
FI891761A0 (fi) 1989-04-13
DE3812328A1 (de) 1989-10-26
DK177789A (da) 1989-10-15
JPH026449A (ja) 1990-01-10
EP0337334A3 (de) 1992-05-20
NZ228707A (en) 1992-03-26
EP0337334A2 (de) 1989-10-18
DK177789D0 (da) 1989-04-13
FI891761A (fi) 1989-10-15
AU3255589A (en) 1989-10-19
CN1037155A (zh) 1989-11-15
PT90273B (pt) 1994-07-29
PT90273A (pt) 1989-11-10
AU618335B2 (en) 1991-12-19
HUT52786A (en) 1990-08-28
HU206888B (en) 1993-01-28
KR890016062A (ko) 1989-11-28

Similar Documents

Publication Publication Date Title
ZA902185B (en) Amino acid derivatives
AU3079789A (en) Amino acid derivatives
EP0416373A3 (en) Amino acid derivatives
ZA882347B (en) Amino acid derivatives
ZA887322B (en) Amino acid derivatives
ZA902444B (en) Amino acid derivatives
ZA893199B (en) Amino acid derivatives
ZA892720B (en) Amino acid derivatives
ZA887373B (en) Amino acid derivatives
ZA883782B (en) Amino acid derivatives
ZA899114B (en) Amino acid derivatives
ZA892059B (en) Amino acid derivatives
ZA902395B (en) Amino acid derivatives
ZA891265B (en) Amino acid derivatives
GB8707515D0 (en) Amino acid derivatives
ZA907585B (en) Amino acid derivatives
HRP930443A2 (en) Amino acid derivatives
ZA89906B (en) Amino acid derivatives
ZA894285B (en) Amino acid derivatives
ZA891659B (en) Amino acid derivatives
ZA891464B (en) Amino acid derivatives
IE882767L (en) Amino acid derivatives
IE880986L (en) Amino acid derivatives
IE890695L (en) Amino acid derivatives
IE891383L (en) Amino acid derivatives