ZA887408B - Monohydrate and solvates of a new beta-lactam antibiotic - Google Patents

Monohydrate and solvates of a new beta-lactam antibiotic

Info

Publication number
ZA887408B
ZA887408B ZA887408A ZA887408A ZA887408B ZA 887408 B ZA887408 B ZA 887408B ZA 887408 A ZA887408 A ZA 887408A ZA 887408 A ZA887408 A ZA 887408A ZA 887408 B ZA887408 B ZA 887408B
Authority
ZA
South Africa
Prior art keywords
solvates
monohydrate
lactam antibiotic
new beta
beta
Prior art date
Application number
ZA887408A
Other languages
English (en)
Inventor
John Brennan
Brennan John
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ZA887408B publication Critical patent/ZA887408B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D463/00Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16Nitrogen atoms
    • C07D463/18Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA887408A 1987-10-07 1988-10-03 Monohydrate and solvates of a new beta-lactam antibiotic ZA887408B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10576287A 1987-10-07 1987-10-07

Publications (1)

Publication Number Publication Date
ZA887408B true ZA887408B (en) 1990-06-27

Family

ID=22307652

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA887408A ZA887408B (en) 1987-10-07 1988-10-03 Monohydrate and solvates of a new beta-lactam antibiotic

Country Status (24)

Country Link
EP (1) EP0311365A1 (es)
JP (1) JPH02270871A (es)
KR (1) KR890006643A (es)
CN (1) CN1032442A (es)
AU (1) AU605635B2 (es)
BG (1) BG47035A3 (es)
CS (1) CS270593B2 (es)
DD (1) DD280112A5 (es)
DK (1) DK553888A (es)
FI (1) FI884555A (es)
HU (1) HU205112B (es)
IL (1) IL87904A0 (es)
MX (1) MX13276A (es)
MY (1) MY103554A (es)
NO (1) NO884417L (es)
NZ (1) NZ226451A (es)
OA (1) OA09017A (es)
PH (1) PH26811A (es)
PL (2) PL163113B1 (es)
PT (1) PT88663B (es)
RO (2) RO102423B1 (es)
RU (1) RU1776260C (es)
YU (1) YU46700B (es)
ZA (1) ZA887408B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA887409B (en) * 1987-10-06 1990-06-27 Lilly Co Eli Crystalline beta-lactam hydrate
CS133392A3 (en) * 1991-05-10 1992-11-18 Lilly Co Eli Process for preparing twice blocked1-carba(1-dithia)-3-cephem-4-carboxylic acids

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1472746A (en) * 1973-07-05 1977-05-04 Glaxo Lab Ltd Cephalosporin compounds
US4160863A (en) * 1977-04-07 1979-07-10 Bristol-Myers Company Process for the preparation of the crystalline monohydrate of 7-[D-α-aα-(p-hydroxyphenyl)acetamido]-3-methyl-3-cephem-4-carboxylic acid
JPS5672698A (en) * 1979-11-14 1981-06-16 Kyowa Hakko Kogyo Co Ltd Preparation of optically active cephalosporin analogue
ZA887409B (en) * 1987-10-06 1990-06-27 Lilly Co Eli Crystalline beta-lactam hydrate

Also Published As

Publication number Publication date
JPH02270871A (ja) 1990-11-05
PL159766B1 (pl) 1993-01-29
HUT48883A (en) 1989-07-28
CN1032442A (zh) 1989-04-19
AU2337188A (en) 1989-04-13
MY103554A (en) 1993-07-31
NO884417L (no) 1989-04-10
AU605635B2 (en) 1991-01-17
MX13276A (es) 1993-11-01
IL87904A0 (en) 1989-03-31
HU205112B (en) 1992-03-30
RO102423B1 (en) 1992-08-01
BG47035A3 (en) 1990-04-16
DD280112A5 (de) 1990-06-27
CS270593B2 (en) 1990-07-12
DK553888A (da) 1989-04-08
YU46700B (sh) 1994-04-05
PT88663A (pt) 1989-07-31
PL163113B1 (pl) 1994-02-28
KR890006643A (ko) 1989-06-15
RU1776260C (ru) 1992-11-15
FI884555A (fi) 1989-04-08
PT88663B (pt) 1993-10-29
OA09017A (fr) 1991-03-31
EP0311365A1 (en) 1989-04-12
NO884417D0 (no) 1988-10-05
DK553888D0 (da) 1988-10-04
RO105809B1 (ro) 1992-12-30
PH26811A (en) 1992-11-05
CS666588A2 (en) 1989-11-14
PL275092A1 (en) 1989-05-16
YU184688A (en) 1990-04-30
FI884555A0 (fi) 1988-10-04
NZ226451A (en) 1990-10-26

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