OA09017A - Monohydrate et produits de solvatation d'un nouvel antibiotique de b-lactame. - Google Patents

Monohydrate et produits de solvatation d'un nouvel antibiotique de b-lactame.

Info

Publication number
OA09017A
OA09017A OA59443A OA59443A OA09017A OA 09017 A OA09017 A OA 09017A OA 59443 A OA59443 A OA 59443A OA 59443 A OA59443 A OA 59443A OA 09017 A OA09017 A OA 09017A
Authority
OA
OAPI
Prior art keywords
solvates
monohydrate
novel
lactam antibiotic
lactam
Prior art date
Application number
OA59443A
Other languages
English (en)
Inventor
Brennan John
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of OA09017A publication Critical patent/OA09017A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D463/00Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16Nitrogen atoms
    • C07D463/18Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
OA59443A 1987-10-07 1988-10-05 Monohydrate et produits de solvatation d'un nouvel antibiotique de b-lactame. OA09017A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10576287A 1987-10-07 1987-10-07

Publications (1)

Publication Number Publication Date
OA09017A true OA09017A (fr) 1991-03-31

Family

ID=22307652

Family Applications (1)

Application Number Title Priority Date Filing Date
OA59443A OA09017A (fr) 1987-10-07 1988-10-05 Monohydrate et produits de solvatation d'un nouvel antibiotique de b-lactame.

Country Status (24)

Country Link
EP (1) EP0311365A1 (fr)
JP (1) JPH02270871A (fr)
KR (1) KR890006643A (fr)
CN (1) CN1032442A (fr)
AU (1) AU605635B2 (fr)
BG (1) BG47035A3 (fr)
CS (1) CS270593B2 (fr)
DD (1) DD280112A5 (fr)
DK (1) DK553888A (fr)
FI (1) FI884555A (fr)
HU (1) HU205112B (fr)
IL (1) IL87904A0 (fr)
MX (1) MX13276A (fr)
MY (1) MY103554A (fr)
NO (1) NO884417L (fr)
NZ (1) NZ226451A (fr)
OA (1) OA09017A (fr)
PH (1) PH26811A (fr)
PL (2) PL163113B1 (fr)
PT (1) PT88663B (fr)
RO (2) RO102423B1 (fr)
RU (1) RU1776260C (fr)
YU (1) YU46700B (fr)
ZA (1) ZA887408B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU46699B (sh) * 1987-10-06 1994-04-05 Eli Lilly And Co. Kristalni monohidratni oblik 1-karbacefalosporina
CA2067708A1 (fr) * 1991-05-10 1992-11-11 Richard A. Berglund Methode de preparation d'acides 1-carba(1-dethia)-3-cepheme-4-carboxyliques comportant un double blocage

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1472746A (en) * 1973-07-05 1977-05-04 Glaxo Lab Ltd Cephalosporin compounds
US4160863A (en) * 1977-04-07 1979-07-10 Bristol-Myers Company Process for the preparation of the crystalline monohydrate of 7-[D-α-aα-(p-hydroxyphenyl)acetamido]-3-methyl-3-cephem-4-carboxylic acid
JPS5672698A (en) * 1979-11-14 1981-06-16 Kyowa Hakko Kogyo Co Ltd Preparation of optically active cephalosporin analogue
YU46699B (sh) * 1987-10-06 1994-04-05 Eli Lilly And Co. Kristalni monohidratni oblik 1-karbacefalosporina

Also Published As

Publication number Publication date
NO884417L (no) 1989-04-10
NO884417D0 (no) 1988-10-05
CS666588A2 (en) 1989-11-14
PL163113B1 (pl) 1994-02-28
EP0311365A1 (fr) 1989-04-12
HU205112B (en) 1992-03-30
MY103554A (en) 1993-07-31
YU184688A (en) 1990-04-30
PT88663B (pt) 1993-10-29
PH26811A (en) 1992-11-05
CN1032442A (zh) 1989-04-19
JPH02270871A (ja) 1990-11-05
PT88663A (pt) 1989-07-31
MX13276A (es) 1993-11-01
RO102423B1 (en) 1992-08-01
DD280112A5 (de) 1990-06-27
AU605635B2 (en) 1991-01-17
FI884555A0 (fi) 1988-10-04
KR890006643A (ko) 1989-06-15
YU46700B (sh) 1994-04-05
NZ226451A (en) 1990-10-26
BG47035A3 (en) 1990-04-16
PL159766B1 (pl) 1993-01-29
HUT48883A (en) 1989-07-28
DK553888D0 (da) 1988-10-04
RO105809B1 (ro) 1992-12-30
FI884555A (fi) 1989-04-08
RU1776260C (ru) 1992-11-15
CS270593B2 (en) 1990-07-12
IL87904A0 (en) 1989-03-31
AU2337188A (en) 1989-04-13
ZA887408B (en) 1990-06-27
DK553888A (da) 1989-04-08
PL275092A1 (en) 1989-05-16

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