ZA878927B - Pharmaceutical compositions - Google Patents

Pharmaceutical compositions

Info

Publication number
ZA878927B
ZA878927B ZA878927A ZA878927A ZA878927B ZA 878927 B ZA878927 B ZA 878927B ZA 878927 A ZA878927 A ZA 878927A ZA 878927 A ZA878927 A ZA 878927A ZA 878927 B ZA878927 B ZA 878927B
Authority
ZA
South Africa
Prior art keywords
sub
sup
alkyl
cycloalkyl
phenyl
Prior art date
Application number
ZA878927A
Other languages
English (en)
Inventor
Michael Brian Tyres
Brian Tyres Michael
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40347948&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA878927(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ZA878927B publication Critical patent/ZA878927B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
ZA878927A 1985-06-25 1987-11-27 Pharmaceutical compositions ZA878927B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858516083A GB8516083D0 (en) 1985-06-25 1985-06-25 Heterocyclic compounds
GB868628474A GB8628474D0 (en) 1985-06-25 1986-11-28 Pharmaceutical compositions

Publications (1)

Publication Number Publication Date
ZA878927B true ZA878927B (en) 1988-10-26

Family

ID=40347948

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA878927A ZA878927B (en) 1985-06-25 1987-11-27 Pharmaceutical compositions

Country Status (22)

Country Link
US (2) US4753789A (de)
EP (2) EP0431443A3 (de)
JP (2) JPS6253920A (de)
AT (2) ATE134510T1 (de)
AU (2) AU609028B2 (de)
BE (1) BE1002249A4 (de)
CA (1) CA1296637C (de)
CH (1) CH672068A5 (de)
CY (1) CY2000A (de)
DE (2) DE3650488T2 (de)
DK (1) DK624687A (de)
FR (1) FR2613934B1 (de)
GB (3) GB8516083D0 (de)
HK (1) HK82597A (de)
IE (1) IE60908B1 (de)
IL (1) IL84638A (de)
IT (1) IT1211937B (de)
NL (1) NL8702853A (de)
NZ (1) NZ222743A (de)
SE (1) SE8704747L (de)
SG (1) SG43311A1 (de)
ZA (1) ZA878927B (de)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0405617A3 (en) * 1985-03-14 1992-11-25 Beecham Group P.L.C. Medicaments for the treatment of anxiety
GB8516083D0 (en) * 1985-06-25 1985-07-31 Glaxo Group Ltd Heterocyclic compounds
US5578628A (en) * 1985-06-25 1996-11-26 Glaxo Group Limited Medicaments for the treatment of nausea and vomiting
GB8627909D0 (en) * 1986-11-21 1986-12-31 Glaxo Group Ltd Medicaments
US5330982A (en) * 1986-12-17 1994-07-19 Glaxo Group Limited Pharmaceutical composition containing a 5-HT receptor antagonist and an H+ K+ Atpase inhibitor and a method of treating gastrointestingal disorders therewith
AU618520B2 (en) * 1986-12-17 1992-01-02 Glaxo Group Limited Medicaments
GB8630080D0 (en) * 1986-12-17 1987-01-28 Glaxo Group Ltd Medicaments
GB8630071D0 (en) * 1986-12-17 1987-01-28 Glaxo Group Ltd Medicaments
GB8630079D0 (en) * 1986-12-17 1987-01-28 Glaxo Group Ltd Medicaments
JPH0754759B2 (ja) * 1987-04-27 1995-06-07 日本電信電話株式会社 プラズマ処理方法および装置並びにプラズマ処理装置用モード変換器
US4943428A (en) * 1987-07-10 1990-07-24 Wright State University Stimulation of serotonin-1A receptors in mammals to alleviate motion sickness and emesis induced by chemical agents
DE3822792C2 (de) * 1987-07-11 1997-11-27 Sandoz Ag Neue Verwendung von 5HT¶3¶-Antagonisten
GB8805269D0 (en) * 1988-03-04 1988-04-07 Glaxo Group Ltd Medicaments
GB8806224D0 (en) * 1988-03-16 1988-04-13 Johnson Matthey Plc Platinum chemotherapeutic product
GB8816187D0 (en) * 1988-07-07 1988-08-10 Glaxo Group Ltd Medicaments
US5047246A (en) * 1988-09-09 1991-09-10 Bristol-Myers Company Direct compression cyclophosphamide tablet
AU627221B2 (en) * 1988-09-27 1992-08-20 Fujisawa Pharmaceutical Co., Ltd. Pyridoindole derivatives and processes for preparation thereof
GB8904182D0 (en) * 1989-02-23 1989-04-05 Glaxo Canada Pharmaceutical compositions
US5039528A (en) * 1989-12-11 1991-08-13 Olney John W EAA antagonists as anti-emetic drugs
US4971651A (en) * 1990-02-05 1990-11-20 Hitachi, Ltd. Microwave plasma processing method and apparatus
JPH06509073A (ja) * 1991-06-26 1994-10-13 セプラコア，インコーポレーテッド 光学的に純粋なｓ（−）オンダンセトロンを使用する嘔吐、吐き気および他の障害の治療のための方法および組成物
CA2112487C (en) * 1991-06-26 2003-04-15 James W. Young Method and compositions for treating emesis, nausea and other disorders using optically pure r(+) ondansetron
EP1082959A1 (de) * 1991-09-20 2001-03-14 Glaxo Group Limited NK1 Antagonisten zur Behandlung von Depression
EP0688216A1 (de) * 1993-03-08 1995-12-27 Fujisawa Pharmaceutical Co., Ltd. Medikament zur behandlung und prävention von zerebrovaskulären erkrankungen
GB9423511D0 (en) * 1994-11-22 1995-01-11 Glaxo Wellcome Inc Compositions
JP2002538102A (ja) 1999-03-01 2002-11-12 セプラコア インコーポレーテッド 光学的に純粋なｒ（＋）オンダンセトロンを使用する無呼吸および無呼吸障害の治療方法
KR100434390B1 (ko) * 2001-04-20 2004-06-04 안국약품 주식회사 1,2,3,9-테트라히드로-9-메틸-3-[(2-메틸-1ｈ-이미다졸-1-일)메틸]-4ｈ-카바졸-4-온을 유효성분으로 하는 비강분무용조성물
DE10393729T5 (de) * 2002-11-15 2005-10-13 Helsinn Healthcare S.A. Verfahren zur Behandlung von Emesis
US20040147510A1 (en) * 2003-01-13 2004-07-29 Dynogen Pharmaceuticals, Inc. Method of treating nausea, vomiting, retching or any combination thereof
US8598219B2 (en) 2003-01-30 2013-12-03 Helsinn Healthcare Sa Liquid pharmaceutical formulations of palonosetron
JO2735B1 (en) * 2003-01-30 2013-09-15 هيلسين هيلث كير أس ايه. Liquid pharmaceutical formations of balloonosterone
TWI355936B (en) * 2003-02-18 2012-01-11 Helsinn Healthcare Sa Uses of palonosetron hydrochloride
US7390503B1 (en) 2003-08-22 2008-06-24 Barr Laboratories, Inc. Ondansetron orally disintegrating tablets
US20060167072A1 (en) * 2004-01-30 2006-07-27 Helsinn Healthcare Sa Liquid pharmaceutical formulations of palonosetron
US7288660B2 (en) * 2004-05-07 2007-10-30 Taro Pharmaceutical Industries Limited Process for preparing ondansetron hydrochloride dihydrate having a defined particle size
US20060068010A1 (en) * 2004-09-30 2006-03-30 Stephen Turner Method for improving the bioavailability of orally delivered therapeutics
US20060293309A1 (en) * 2005-03-28 2006-12-28 Dynogen Pharmaceuticals, Inc. Method of treating disorders and conditions using peripherally-restricted antagonists and inhibitors
WO2008049552A1 (en) * 2006-10-24 2008-05-02 Helsinn Healthcare S.A. Soft capsules comprising palonosetron hydrochloride having improved stability and bioavailability
JP2010050046A (ja) 2008-08-25 2010-03-04 Hitachi High-Technologies Corp プラズマ処理装置
EP2519226A1 (de) 2009-12-28 2012-11-07 MonoSol Rx, LLC Oral verabreichte filmdosierungsformen mit ondansetron
MX342993B (es) 2013-04-25 2016-10-13 Inst Mexicano Del Petróleo Proceso de obtencion de copolimeros aleatorios derivados del acido itaconico y/o sus isomeros y alquenil sulfonatos de sodio y uso del producto obtenido.
WO2018129434A1 (en) 2017-01-09 2018-07-12 Gt Biopharma, Inc. Use and composition for treating myasthenia gravis and other myasthenic syndromes

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0040489A1 (de) * 1980-05-17 1981-11-25 FISONS plc Mischungen, Salze, Packungen und pharmazeutische Zusammensetzungen mit Gehalt an 5-(2-Hydroxypropoxy)-4-oxo-8-propyl-4H-1-benzopyran-2-carbonsäure oder einem Derivat derselben und einem H2-Rezeptoren antagonisierenden Antihistamin
BE894285A (fr) * 1981-09-04 1983-03-02 Glaxo Group Ltd Composition pharmaceutique contenant un medicament anti-inflammatoire et de la ranitidine ou un sel de ce compose
FR2557110B1 (fr) * 1983-12-23 1989-11-24 Sandoz Sa Nouveaux derives d'amines cycliques, leur preparation et leur utilisation comme medicaments
FR2561244B1 (fr) * 1984-01-25 1988-03-04 Glaxo Group Ltd Composes heterocycliques du type tetrahydrocarbazolone, procede pour leur preparation et composition pharmaceutique les comprenant
US4695578A (en) * 1984-01-25 1987-09-22 Glaxo Group Limited 1,2,3,9-tetrahydro-3-imidazol-1-ylmethyl-4H-carbazol-4-ones, composition containing them, and method of using them to treat neuronal 5HT function disturbances
EP0191562B1 (de) * 1985-01-23 1991-07-10 Glaxo Group Limited Tetrahydrocarbazolonderivate
EP0405617A3 (en) * 1985-03-14 1992-11-25 Beecham Group P.L.C. Medicaments for the treatment of anxiety
GB8516083D0 (en) * 1985-06-25 1985-07-31 Glaxo Group Ltd Heterocyclic compounds
GB8630079D0 (en) * 1986-12-17 1987-01-28 Glaxo Group Ltd Medicaments

Also Published As

Publication number Publication date
SE8704747D0 (sv) 1987-11-27
CH672068A5 (de) 1989-10-31
EP0226266A2 (de) 1987-06-24
NL8702853A (nl) 1988-06-16
ATE134510T1 (de) 1996-03-15
FR2613934A1 (fr) 1988-10-21
GB8727836D0 (en) 1987-12-31
GB8516083D0 (en) 1985-07-31
DK624687D0 (da) 1987-11-27
JPS63198623A (ja) 1988-08-17
SG43311A1 (en) 1997-10-17
US4753789A (en) 1988-06-28
IT1211937B (it) 1989-11-08
CY2000A (en) 1997-12-05
EP0226266A3 (en) 1990-01-24
EP0431443A2 (de) 1991-06-12
US4929632A (en) 1990-05-29
DE3650488D1 (de) 1996-04-04
DK624687A (da) 1988-05-29
ATA312587A (de) 1992-05-15
AU6703786A (en) 1988-06-30
SE8704747L (sv) 1988-05-29
AU8191487A (en) 1988-06-02
IE873230L (en) 1988-05-28
HK82597A (en) 1997-06-27
GB2200046B (en) 1990-09-26
EP0226266B1 (de) 1996-02-28
EP0431443A3 (en) 1991-09-18
AU616386B2 (en) 1991-10-31
GB2200046A (en) 1988-07-27
JPH0324447B2 (de) 1991-04-03
FR2613934B1 (fr) 1993-07-09
IE60908B1 (en) 1994-08-24
JPS6253920A (ja) 1987-03-09
AT395374B (de) 1992-12-10
NZ222743A (en) 1991-09-25
CA1296637C (en) 1992-03-03
IL84638A (en) 1992-05-25
IT8748643A0 (it) 1987-11-27
BE1002249A4 (fr) 1990-11-06
DE3650488T2 (de) 1996-09-05
AU609028B2 (en) 1991-04-26
GB8628474D0 (en) 1987-01-07
DE3740351A1 (de) 1988-06-09

Similar Documents

Publication Publication Date Title
AU616386B2 (en) Pharmaceutical compositions
ES8105292A1 (es) Procedimiento para la obtencion de derivado de la difenilu- rea halogenosustituidos
ES8506615A1 (es) Un procedimiento para la preparacion de carboxamidas
EP0563127B1 (de) Verbessertes behandlungsverfahren für krebs
EP0271013A3 (en) Basic substituted phenyl acetonitriles, their preparation and medicaments containing them
EP0210753A3 (de) Arzneimittel gegen Tumore
IL70253A (en) N-nitrosourea phosphoric acid derivatives,their preparation and pharmaceutical compositions containing them
NZ227082A (en) N-(23-vinblastinoyl) derivatives of 1-aminomethyl-phosphonic acid; process for their preparation; and pharmaceutical compositions containing them
CA2211982A1 (en) Substituted indanylidineacetylguanidines, process for their preparation,their use as medicaments or diagnostic and medicaments containing them
MY103293A (en) N-imidazolyl derivatives of bicyclic compounds useful in medicine
ES2001893A6 (es) Procedimiento para la obtencion de derivados de metilendioxifenantreno
ES8504112A1 (es) Procedimiento para la obtencion de derivados de la benzamidina de actividad antimicrobiana
EP0204172A3 (en) Phenylpyrazine derivatives, processes for preparing them, pharmaceutical composition and use
ES487971A1 (es) Procedimiento para la preparacion de nuevos derivados de p-cloroacetofenona oxima con actividad analgesica
ES8504816A1 (es) Un procedimiento de preparacion de un derivado de cefalosporina
ES8201152A1 (es) Procedimiento para la preparacion de acidos 5-sulfamoilorta-nilicos
ES8504701A1 (es) Procedimiento para preparar derivados de 3-aril-3-pirrolina