ATE134510T1 - Verwendung eines tetrahydrocarbazolonderivates zur herstellung von arzneimitteln - Google Patents

Verwendung eines tetrahydrocarbazolonderivates zur herstellung von arzneimitteln

Info

Publication number
ATE134510T1
ATE134510T1 AT86304831T AT86304831T ATE134510T1 AT E134510 T1 ATE134510 T1 AT E134510T1 AT 86304831 T AT86304831 T AT 86304831T AT 86304831 T AT86304831 T AT 86304831T AT E134510 T1 ATE134510 T1 AT E134510T1
Authority
AT
Austria
Prior art keywords
sub
sup
alkyl
cycloalkyl
phenyl
Prior art date
Application number
AT86304831T
Other languages
English (en)
Inventor
Michael Brian Tyers
Ian Harold Coates
David Cedric Humber
George Blanch Ewan
James Angus Bell
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40347948&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE134510(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE134510T1 publication Critical patent/ATE134510T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT86304831T 1985-06-25 1986-06-24 Verwendung eines tetrahydrocarbazolonderivates zur herstellung von arzneimitteln ATE134510T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858516083A GB8516083D0 (en) 1985-06-25 1985-06-25 Heterocyclic compounds
GB868628474A GB8628474D0 (en) 1985-06-25 1986-11-28 Pharmaceutical compositions

Publications (1)

Publication Number Publication Date
ATE134510T1 true ATE134510T1 (de) 1996-03-15

Family

ID=40347948

Family Applications (2)

Application Number Title Priority Date Filing Date
AT86304831T ATE134510T1 (de) 1985-06-25 1986-06-24 Verwendung eines tetrahydrocarbazolonderivates zur herstellung von arzneimitteln
AT0312587A AT395374B (de) 1985-06-25 1987-11-27 Pharmazeutisches praeparat

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT0312587A AT395374B (de) 1985-06-25 1987-11-27 Pharmazeutisches praeparat

Country Status (22)

Country Link
US (2) US4753789A (de)
EP (2) EP0226266B1 (de)
JP (2) JPS6253920A (de)
AT (2) ATE134510T1 (de)
AU (2) AU609028B2 (de)
BE (1) BE1002249A4 (de)
CA (1) CA1296637C (de)
CH (1) CH672068A5 (de)
CY (1) CY2000A (de)
DE (2) DE3650488T2 (de)
DK (1) DK624687A (de)
FR (1) FR2613934B1 (de)
GB (3) GB8516083D0 (de)
HK (1) HK82597A (de)
IE (1) IE60908B1 (de)
IL (1) IL84638A (de)
IT (1) IT1211937B (de)
NL (1) NL8702853A (de)
NZ (1) NZ222743A (de)
SE (1) SE8704747L (de)
SG (1) SG43311A1 (de)
ZA (1) ZA878927B (de)

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DE3689974T2 (de) * 1985-03-14 1994-11-03 Beecham Group Plc Arzneimittel zur Behandlung von Emesis.
US5578628A (en) * 1985-06-25 1996-11-26 Glaxo Group Limited Medicaments for the treatment of nausea and vomiting
GB8516083D0 (en) * 1985-06-25 1985-07-31 Glaxo Group Ltd Heterocyclic compounds
GB8627909D0 (en) * 1986-11-21 1986-12-31 Glaxo Group Ltd Medicaments
GB8630080D0 (en) * 1986-12-17 1987-01-28 Glaxo Group Ltd Medicaments
GB8630071D0 (en) * 1986-12-17 1987-01-28 Glaxo Group Ltd Medicaments
IE60991B1 (en) * 1986-12-17 1994-09-07 Glaxo Group Ltd Use of ketone derivatives in the treatment of cognitive disorders
GB8630079D0 (en) * 1986-12-17 1987-01-28 Glaxo Group Ltd Medicaments
US5330982A (en) * 1986-12-17 1994-07-19 Glaxo Group Limited Pharmaceutical composition containing a 5-HT receptor antagonist and an H+ K+ Atpase inhibitor and a method of treating gastrointestingal disorders therewith
JPH0754759B2 (ja) * 1987-04-27 1995-06-07 日本電信電話株式会社 プラズマ処理方法および装置並びにプラズマ処理装置用モード変換器
US4943428A (en) * 1987-07-10 1990-07-24 Wright State University Stimulation of serotonin-1A receptors in mammals to alleviate motion sickness and emesis induced by chemical agents
DE3822792C2 (de) * 1987-07-11 1997-11-27 Sandoz Ag Neue Verwendung von 5HT¶3¶-Antagonisten
GB8805269D0 (en) * 1988-03-04 1988-04-07 Glaxo Group Ltd Medicaments
GB8806224D0 (en) * 1988-03-16 1988-04-13 Johnson Matthey Plc Platinum chemotherapeutic product
GB8816187D0 (en) * 1988-07-07 1988-08-10 Glaxo Group Ltd Medicaments
US5047246A (en) * 1988-09-09 1991-09-10 Bristol-Myers Company Direct compression cyclophosphamide tablet
AU627221B2 (en) * 1988-09-27 1992-08-20 Fujisawa Pharmaceutical Co., Ltd. Pyridoindole derivatives and processes for preparation thereof
GB8904182D0 (en) * 1989-02-23 1989-04-05 Glaxo Canada Pharmaceutical compositions
US5039528A (en) * 1989-12-11 1991-08-13 Olney John W EAA antagonists as anti-emetic drugs
US4971651A (en) * 1990-02-05 1990-11-20 Hitachi, Ltd. Microwave plasma processing method and apparatus
EP0591395A1 (de) * 1991-06-26 1994-04-13 Sepracor, Inc. Verfahren und zusammensetzungen zur behandlung von erbrechen, übelkeit und anderen störungen unter verwendung von optisch reinem s(-)-odansetron
WO1993000074A1 (en) * 1991-06-26 1993-01-07 Sepracor, Inc. Method and compositions for treating emesis, nausea and other disorders using optically pure r(+) ondansetron
EP0916346A3 (de) * 1991-09-20 2000-12-06 Glaxo Group Limited NK-1 Rezeptor Antagonisten und 5HT3 Rezeptor Antagonisten zur Behandlung von Emesis
CA2157671A1 (en) * 1993-03-08 1994-09-15 Kiyotaka Katsuta Medicament for treating or preventing cerebrovascular diseases
GB9423511D0 (en) * 1994-11-22 1995-01-11 Glaxo Wellcome Inc Compositions
JP2002538102A (ja) * 1999-03-01 2002-11-12 セプラコア インコーポレーテッド 光学的に純粋なｒ（＋）オンダンセトロンを使用する無呼吸および無呼吸障害の治療方法
KR100434390B1 (ko) * 2001-04-20 2004-06-04 안국약품 주식회사 1,2,3,9-테트라히드로-9-메틸-3-[(2-메틸-1ｈ-이미다졸-1-일)메틸]-4ｈ-카바졸-4-온을 유효성분으로 하는 비강분무용조성물
WO2004045615A1 (en) * 2002-11-15 2004-06-03 Helsinn Healthcare Sa Palonosetron for the treatment of chemotherapy-induced emesis
BRPI0406748A (pt) * 2003-01-13 2005-12-20 Dynogen Pharmaceuticals Inc Método de tratamento de náusea, vÈmito e ânsia de vÈmito ou qualquer combinação destes em um paciente que necessite do mesmo e composição farmacêutica
JO2735B1 (en) * 2003-01-30 2013-09-15 هيلسين هيلث كير أس ايه. Liquid pharmaceutical formations of balloonosterone
US8598219B2 (en) 2003-01-30 2013-12-03 Helsinn Healthcare Sa Liquid pharmaceutical formulations of palonosetron
TWI355936B (en) * 2003-02-18 2012-01-11 Helsinn Healthcare Sa Uses of palonosetron hydrochloride
US7390503B1 (en) 2003-08-22 2008-06-24 Barr Laboratories, Inc. Ondansetron orally disintegrating tablets
US20060167072A1 (en) * 2004-01-30 2006-07-27 Helsinn Healthcare Sa Liquid pharmaceutical formulations of palonosetron
WO2005108392A2 (en) * 2004-05-07 2005-11-17 Taro Pharmaceutical Industries Ltd. Process for preparing ondansetron hydrochloride dihydrate having a defined particle size
US20060068010A1 (en) * 2004-09-30 2006-03-30 Stephen Turner Method for improving the bioavailability of orally delivered therapeutics
WO2006105117A2 (en) * 2005-03-28 2006-10-05 Dynogen Pharmaceuticals, Inc. Method of treating disorders and conditions using peripherally-restricted antagonists and inhibitors
AU2007308378B2 (en) * 2006-10-24 2013-02-21 Helsinn Healthcare S.A. Soft capsules comprising palonosetron hydrochloride having improved stability and bioavailability
JP2010050046A (ja) 2008-08-25 2010-03-04 Hitachi High-Technologies Corp プラズマ処理装置
CA2784587A1 (en) 2009-12-28 2011-07-28 Monosol Rx, Llc Orally administrable film dosage forms containing ondansetron
MX342993B (es) 2013-04-25 2016-10-13 Inst Mexicano Del Petróleo Proceso de obtencion de copolimeros aleatorios derivados del acido itaconico y/o sus isomeros y alquenil sulfonatos de sodio y uso del producto obtenido.
WO2018129434A1 (en) 2017-01-09 2018-07-12 Gt Biopharma, Inc. Use and composition for treating myasthenia gravis and other myasthenic syndromes

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0040489A1 (de) * 1980-05-17 1981-11-25 FISONS plc Mischungen, Salze, Packungen und pharmazeutische Zusammensetzungen mit Gehalt an 5-(2-Hydroxypropoxy)-4-oxo-8-propyl-4H-1-benzopyran-2-carbonsäure oder einem Derivat derselben und einem H2-Rezeptoren antagonisierenden Antihistamin
BE894285A (fr) * 1981-09-04 1983-03-02 Glaxo Group Ltd Composition pharmaceutique contenant un medicament anti-inflammatoire et de la ranitidine ou un sel de ce compose
FR2557110B1 (fr) * 1983-12-23 1989-11-24 Sandoz Sa Nouveaux derives d'amines cycliques, leur preparation et leur utilisation comme medicaments
US4695578A (en) * 1984-01-25 1987-09-22 Glaxo Group Limited 1,2,3,9-tetrahydro-3-imidazol-1-ylmethyl-4H-carbazol-4-ones, composition containing them, and method of using them to treat neuronal 5HT function disturbances
DE3502508A1 (de) * 1984-01-25 1985-08-14 Glaxo Group Ltd., London Heterocyclische verbindungen
AU583343B2 (en) * 1985-01-23 1989-04-27 Glaxo Group Limited Heterocyclic compounds
DE3689974T2 (de) * 1985-03-14 1994-11-03 Beecham Group Plc Arzneimittel zur Behandlung von Emesis.
GB8516083D0 (en) * 1985-06-25 1985-07-31 Glaxo Group Ltd Heterocyclic compounds
GB8630079D0 (en) * 1986-12-17 1987-01-28 Glaxo Group Ltd Medicaments

Also Published As

Publication number Publication date
IL84638A (en) 1992-05-25
EP0226266A3 (en) 1990-01-24
BE1002249A4 (fr) 1990-11-06
AU8191487A (en) 1988-06-02
AT395374B (de) 1992-12-10
EP0226266A2 (de) 1987-06-24
EP0226266B1 (de) 1996-02-28
US4753789A (en) 1988-06-28
DK624687A (da) 1988-05-29
EP0431443A3 (en) 1991-09-18
DK624687D0 (da) 1987-11-27
SE8704747L (sv) 1988-05-29
FR2613934A1 (fr) 1988-10-21
DE3740351A1 (de) 1988-06-09
CH672068A5 (de) 1989-10-31
CY2000A (en) 1997-12-05
IT1211937B (it) 1989-11-08
AU616386B2 (en) 1991-10-31
IE873230L (en) 1988-05-28
NZ222743A (en) 1991-09-25
AU609028B2 (en) 1991-04-26
US4929632A (en) 1990-05-29
JPH0324447B2 (de) 1991-04-03
NL8702853A (nl) 1988-06-16
GB8516083D0 (en) 1985-07-31
IE60908B1 (en) 1994-08-24
GB2200046B (en) 1990-09-26
GB2200046A (en) 1988-07-27
SG43311A1 (en) 1997-10-17
GB8628474D0 (en) 1987-01-07
HK82597A (en) 1997-06-27
ATA312587A (de) 1992-05-15
GB8727836D0 (en) 1987-12-31
FR2613934B1 (fr) 1993-07-09
EP0431443A2 (de) 1991-06-12
IT8748643A0 (it) 1987-11-27
DE3650488T2 (de) 1996-09-05
ZA878927B (en) 1988-10-26
CA1296637C (en) 1992-03-03
JPS63198623A (ja) 1988-08-17
DE3650488D1 (de) 1996-04-04
AU6703786A (en) 1988-06-30
JPS6253920A (ja) 1987-03-09
SE8704747D0 (sv) 1987-11-27

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time