ZA877385B - Combination of angiotensin-converting enzyme inhibitors with calcium antagonists as well as their use in drugs - Google Patents

Combination of angiotensin-converting enzyme inhibitors with calcium antagonists as well as their use in drugs

Info

Publication number
ZA877385B
ZA877385B ZA877385A ZA877385A ZA877385B ZA 877385 B ZA877385 B ZA 877385B ZA 877385 A ZA877385 A ZA 877385A ZA 877385 A ZA877385 A ZA 877385A ZA 877385 B ZA877385 B ZA 877385B
Authority
ZA
South Africa
Prior art keywords
angiotensin
drugs
combination
well
converting enzyme
Prior art date
Application number
ZA877385A
Other languages
English (en)
Inventor
Reinhard Becker
Becker Reinhard
Hansjoerg Urbach
Urbach Hansjoerg
Rainer Henning
Henning Rainer
Wolfgang Rueger
Rueger Wolfgang
Volker Teetz
Teetz Volker
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36747182&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA877385(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA877385B publication Critical patent/ZA877385B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/556—Angiotensin converting enzyme inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA877385A 1986-10-02 1987-10-01 Combination of angiotensin-converting enzyme inhibitors with calcium antagonists as well as their use in drugs ZA877385B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19863633496 DE3633496A1 (de) 1986-10-02 1986-10-02 Kombination von angiotensin-converting-enzyme-hemmern mit calciumantagonisten sowie deren verwendung in arzneimitteln
AT0260087A AT402894B (de) 1986-10-02 1987-10-08 Kombination von angiotensin-converting-enzyme- hemmern mit calciumantagonisten sowie ein erzeugnis, das diese enthält, zur anwendung bei der behandlung des bluthochdrucks

Publications (1)

Publication Number Publication Date
ZA877385B true ZA877385B (en) 1988-05-25

Family

ID=36747182

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA877385A ZA877385B (en) 1986-10-02 1987-10-01 Combination of angiotensin-converting enzyme inhibitors with calcium antagonists as well as their use in drugs

Country Status (26)

Country Link
US (3) US5098910A (fr)
EP (1) EP0265685B1 (fr)
JP (2) JP2752043B2 (fr)
KR (1) KR970005838B1 (fr)
AR (1) AR243083A1 (fr)
AT (2) ATE78697T1 (fr)
AU (1) AU611863B2 (fr)
CA (1) CA1317545C (fr)
DD (1) DD272035A5 (fr)
DE (3) DE3633496A1 (fr)
DK (1) DK167904B1 (fr)
EG (1) EG18081A (fr)
ES (1) ES2043626T3 (fr)
FI (1) FI874281A (fr)
GR (1) GR3006042T3 (fr)
HU (1) HU199302B (fr)
IE (1) IE59975B1 (fr)
IL (1) IL84054A (fr)
LU (1) LU90345I2 (fr)
MA (1) MA21072A1 (fr)
MX (1) MX8639A (fr)
NL (1) NL980030I2 (fr)
NO (2) NO175621C (fr)
NZ (1) NZ221989A (fr)
PT (1) PT85843B (fr)
ZA (1) ZA877385B (fr)

Families Citing this family (33)

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DE3413710A1 (de) * 1984-04-12 1985-10-24 Hoechst Ag, 6230 Frankfurt Verfahren zur behandlung der herzinsuffizienz
US5684016A (en) * 1984-04-12 1997-11-04 Hoechst Aktiengesellschaft Method of treating cardiac insufficiency
DE3633496A1 (de) * 1986-10-02 1988-04-14 Hoechst Ag Kombination von angiotensin-converting-enzyme-hemmern mit calciumantagonisten sowie deren verwendung in arzneimitteln
NL8702502A (nl) * 1986-11-03 1988-06-01 Sandoz Ag Farmaceutisch preparaat voor toepassing tegen hypertensie en congestieve cardiale insufficientie.
FR2607004B1 (fr) * 1986-11-20 1990-06-01 Synthelabo Compositions pharmaceutiques contenant du diltiazem et un inhibiteur de l'enzyme de conversion de l'angiotensine
USH734H (en) * 1988-03-07 1990-02-06 E. R. Squibb & Sons, Inc. Method for inhibiting onset of or treating migraine headaches employing an ACE inhibitor
JPH01275529A (ja) * 1988-03-21 1989-11-06 E R Squibb & Sons Inc 晩発性運動障害の抑制治療剤
DE3818245A1 (de) * 1988-05-28 1989-12-07 Hoechst Ag Kombination von angiotensin-converting-enzyme-hemmern mit kaliumkanal-modulatoren sowie deren verwendung in arzneimitteln
EP0391462A1 (fr) * 1989-04-05 1990-10-10 Janssen Pharmaceutica N.V. Combinaisons synergiques à kétanserin
TW197945B (fr) * 1990-11-27 1993-01-11 Hoechst Ag
DE4109134A1 (de) * 1991-03-20 1992-09-24 Knoll Ag Erzeugnisse, enthaltend verapamil und trandolapril
US6162802A (en) * 1992-03-10 2000-12-19 Papa; Joseph Synergistic combination therapy using benazepril and amlodipine for the treatment of cardiovascular disorders and compositions therefor
DE4314962A1 (de) * 1993-05-06 1994-11-10 Bayer Ag Substituierte Piperazine
JP3057471B2 (ja) 1993-06-07 2000-06-26 武田薬品工業株式会社 アンジオテンシンｉｉ介在性諸疾患の予防または治療剤
TW483763B (en) * 1994-09-02 2002-04-21 Astra Ab Pharmaceutical composition comprising of ramipril and dihydropyridine compound
US5658832A (en) * 1994-10-17 1997-08-19 Regents Of The University Of California Method of forming a spacer for field emission flat panel displays
CA2215234C (fr) 1995-03-16 2001-12-11 Pfizer Inc. Composition renfermant de l'amlopidine ou un sel, ou de la felodipine et un inhibiteur de l'enzyme de conversion de l'angiotensine
FR2733911B1 (fr) * 1995-05-09 1998-05-29 Takeda Chemical Industries Ltd Composition pharmaceutique pour maladies renales ou cardio-vasculaires
EP0795327A1 (fr) * 1996-03-13 1997-09-17 Pfizer Inc. Utilisation de l'amlodipine pour le traitement et la prophylaxie de l'insuffisance cardiaque congestive d'origine non-ischémique
SE9903028D0 (sv) * 1999-08-27 1999-08-27 Astra Ab New use
DK1216038T3 (da) * 1999-08-30 2005-12-27 Sanofi Aventis Deutschland Anvendelse af inhibitorer af reninangiotensinsystemet ved forebyggelsen af cardiovaskulære hændelser
US20040005359A1 (en) * 2002-06-27 2004-01-08 Cheng Xiu Xiu Controlled release oral dosage form
US20050101640A1 (en) * 2002-10-16 2005-05-12 Recordati Ireland Limited Lisinopril/lercanidipine combination therapy
US20040147566A1 (en) * 2002-10-16 2004-07-29 Amedeo Leonardi Lisinopril/lercanidipine combination therapy
US20050032784A1 (en) * 2003-04-01 2005-02-10 University Of Florida Research Foundation, Inc. Combination drug therapy for treating hypertension
KR100546710B1 (ko) 2003-07-02 2006-01-26 엘지.필립스 엘시디 주식회사 액정표시장치의 아날로그 버퍼회로
AU2005304664A1 (en) * 2004-11-05 2006-05-18 King Pharmaceuticals Research & Development, Inc. Stabilized ramipril compositions and methods of making
GB0624084D0 (en) * 2006-12-01 2007-01-10 Selamine Ltd Ramipril amino acid salts
GB0624090D0 (en) * 2006-12-01 2007-01-10 Selamine Ltd Ramipril amine salts
GB0624087D0 (en) * 2006-12-01 2007-01-10 Selamine Ltd Ramipril combination salt
WO2009125944A2 (fr) * 2008-04-10 2009-10-15 한올제약주식회사 Préparation pharmaceutique contenant un inhibiteur des canaux calciques non dihydropyridine et un inhibiteur du récepteur de l'angiotensine 2
ES2483154T3 (es) 2010-02-24 2014-08-05 Sanofi-Aventis Deutschland Gmbh Formulaciones farmacéuticas sólidas de ramipril y besilato de amlodipino y su preparación
RU2543637C2 (ru) * 2012-12-06 2015-03-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Волгоградский государственный медицинский университет" Министерства здавоохранения Российской Федерации Пролонгированная фармацевтическая композиция гипотензивного действия и способ ее изготовления

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DE3324263A1 (de) * 1983-07-06 1985-01-17 Hoechst Ag, 6230 Frankfurt Derivate der 2-azabicyclo(3.1.0)hexan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung sowie 2-azabicyclo(3.1.0)hexan-derivate als zwischenprodukte und verfahren zu deren herstellung
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DE3437917A1 (de) * 1984-10-17 1986-04-17 Bayer Ag, 5090 Leverkusen Kombination von dihydropyridinen mit ace-hemmern sowie ihre verwendung in arzneimitteln
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US5256687A (en) * 1985-09-09 1993-10-26 Hoechst Aktiengesellschaft Pharmaceutical composition for the treatment of high blood pressure
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FR2607004B1 (fr) * 1986-11-20 1990-06-01 Synthelabo Compositions pharmaceutiques contenant du diltiazem et un inhibiteur de l'enzyme de conversion de l'angiotensine

Also Published As

Publication number Publication date
EP0265685B1 (fr) 1992-07-29
IE59975B1 (en) 1994-05-04
MA21072A1 (fr) 1988-07-01
DE19975008I2 (de) 2004-07-01
FI874281A (fi) 1988-04-03
MX8639A (es) 1993-11-01
NO175621C (no) 1994-11-09
LU90345I2 (fr) 1999-04-06
DD272035A5 (de) 1989-09-27
ES2043626T3 (es) 1994-01-01
DE3633496A1 (de) 1988-04-14
EP0265685A2 (fr) 1988-05-04
AT402894B (de) 1997-09-25
JP3003995B2 (ja) 2000-01-31
US5721244A (en) 1998-02-24
DE3780753D1 (de) 1992-09-03
HUT47030A (en) 1989-01-30
DK516487A (da) 1988-04-03
EG18081A (en) 1991-08-30
IL84054A (en) 1993-01-31
JPH10182456A (ja) 1998-07-07
DK167904B1 (da) 1994-01-03
HU199302B (en) 1990-02-28
NL980030I1 (nl) 1999-01-04
IL84054A0 (en) 1988-03-31
JPS6396136A (ja) 1988-04-27
NO175621B (fr) 1994-08-01
AU611863B2 (en) 1991-06-27
CA1317545C (fr) 1993-05-11
AU7928087A (en) 1988-04-14
EP0265685A3 (en) 1989-10-11
PT85843B (pt) 1991-02-08
NO1998022I1 (no) 1998-10-12
US5500434A (en) 1996-03-19
JP2752043B2 (ja) 1998-05-18
GR3006042T3 (fr) 1993-06-21
IE872636L (en) 1988-04-02
US5098910A (en) 1992-03-24
KR880005150A (ko) 1988-06-28
NO874141L (no) 1988-04-05
FI874281A0 (fi) 1987-09-30
DK516487D0 (da) 1987-10-01
ATA260087A (de) 1997-02-15
NZ221989A (en) 1990-11-27
NO874141D0 (no) 1987-10-01
PT85843A (de) 1987-11-01
NL980030I2 (nl) 1999-10-01
KR970005838B1 (ko) 1997-04-21
AR243083A1 (es) 1993-07-30
ATE78697T1 (de) 1992-08-15

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