ZA875643B - Use of acetyl l-carnitine in the therapeutical treatment of peripheral neuropathies - Google Patents

Use of acetyl l-carnitine in the therapeutical treatment of peripheral neuropathies

Info

Publication number
ZA875643B
ZA875643B ZA875643A ZA875643A ZA875643B ZA 875643 B ZA875643 B ZA 875643B ZA 875643 A ZA875643 A ZA 875643A ZA 875643 A ZA875643 A ZA 875643A ZA 875643 B ZA875643 B ZA 875643B
Authority
ZA
South Africa
Prior art keywords
carnitine
acetyl
peripheral neuropathies
therapeutical treatment
therapeutical
Prior art date
Application number
ZA875643A
Other languages
English (en)
Inventor
Menotti Calvani
Calvani Menotti
Luigi Mosconi
Mosconi Luigi
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of ZA875643B publication Critical patent/ZA875643B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
ZA875643A 1986-08-04 1987-07-30 Use of acetyl l-carnitine in the therapeutical treatment of peripheral neuropathies ZA875643B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT48358/86A IT1196564B (it) 1986-08-04 1986-08-04 Impiego di acetil l-carnitina nel trattamento terapeutico delle neuropatie periferiche

Publications (1)

Publication Number Publication Date
ZA875643B true ZA875643B (en) 1988-11-30

Family

ID=11266089

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA875643A ZA875643B (en) 1986-08-04 1987-07-30 Use of acetyl l-carnitine in the therapeutical treatment of peripheral neuropathies

Country Status (11)

Country Link
US (1) US4751242A (it)
EP (1) EP0256999B1 (it)
JP (1) JPH085786B2 (it)
AT (1) ATE70439T1 (it)
CA (1) CA1298197C (it)
DE (1) DE3775301D1 (it)
DK (1) DK164641C (it)
ES (1) ES2039262T3 (it)
GR (1) GR3003405T3 (it)
IT (1) IT1196564B (it)
ZA (1) ZA875643B (it)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1224842B (it) * 1988-12-27 1990-10-24 Sigma Tau Ind Farmaceuti Uso di derivati della l-carnitina nel trattamento terapeutico delle alterazioni degenerative del sistema nervoso
US5641764A (en) * 1989-03-31 1997-06-24 Peter Maccallum Institute Halogenated DNA ligand radiosensitizers for cancer therapy
IT1230141B (it) * 1989-05-03 1991-10-14 Fidia Spa Impiego di derivati della fosfatidil carnitina per la preparazione di composizioni farmaceutiche aventi attivita' nella terapia delle patologie dell'uomo associate con un danno neuronale.
IT1244636B (it) * 1991-01-04 1994-08-08 Sigma Tau Ind Farmaceuti Uso dell'acetil l-carnitina nel trattamento terapeutico del coma e composizioni farmaceutiche utili in tale trattamento.
IT1245699B (it) * 1991-05-29 1994-10-14 Sigma Tau Ind Farmaceuti Derivati della l-carnitina quali agenti terapeutici per il trattamento delle miopatie, della degenarazione neuronale e per inibire la proteolisi
IT1263004B (it) * 1992-10-08 1996-07-23 Sigma Tau Ind Farmaceuti Impiego della l-carnitina e acil l-carnitine nel trattamento a lungo termine di pazienti diabetici non insulino-dipendenti.
IT1276225B1 (it) * 1995-10-17 1997-10-27 Sigma Tau Ind Farmaceuti Composizioni farmaceutiche contenenti l-carnitina e alcanoil l- carnitine in associazione con resveratrolo o suoi derivati utili per
IT1291127B1 (it) * 1997-04-01 1998-12-29 Sigma Tau Ind Farmaceuti Integratore alimentare per soggetti dediti ad intensa e prolungata attivita' fisica
IT1294227B1 (it) * 1997-08-01 1999-03-24 Sigma Tau Ind Farmaceuti Composizione farmaceutica contenente l-carnitina o una alcanoil l-carnitina e alcoli alifatici a lunga catena utile per la prevenzione
IT1298487B1 (it) * 1997-12-19 2000-01-10 Sigma Tau Ind Farmaceuti Composizioni farmaceutiche comprendenti pentraxina lunga ptx3 per la terapia di patologie di tipo infettivo, infiammatorio o tumorale,
JPH11298323A (ja) 1998-04-16 1999-10-29 Nec Yamagata Ltd 高速ロックアップｐｌｌ回路
KR100645980B1 (ko) * 1998-07-30 2006-11-14 시그마타우 인두스트리에 파르마슈티케 리우니테 에스.피.에이. 항암 활성을 갖는 약제의 제조에서 ｌ-카르니틴 및 그의알카노일 유도체의 용도
US20030199535A1 (en) * 1998-07-30 2003-10-23 Claudio Cavazza Method for preventing and/or treating peripheral neuropathies induced by the administration of an anticancer agent
IT1306178B1 (it) * 1999-07-27 2001-05-30 Sigma Tau Ind Farmaceuti Uso della l-carnitina e dei suoi alcanoil derivati per la preparazionedi un medicamento utile nel trattamento del paziente affetto da
AU7828200A (en) * 1999-09-23 2001-04-24 Juvenon Corporation Nutritional supplement for increased energy and stamina
US6562869B1 (en) * 1999-09-23 2003-05-13 Juvenon, Inc. Nutritional supplement for increased energy and stamina
ITRM20010293A1 (it) * 2001-05-29 2002-11-29 Sigma Tau Ind Farmaceuti Uso della acetil-l-carnetina per la preparazione di un medicamento per la prevenzione del dolore.
ITRM20010294A1 (it) * 2001-05-29 2002-11-29 Sigma Tau Ind Farmaceuti Uso della acetil l-carnetina in associazione con la biotina per il trattamento di pazienti affetti da diabete mellito di tipo ii insulino re
US8173618B2 (en) * 2003-07-25 2012-05-08 University Of Massachusetts Formulations for reducing neuronal degeneration
ITRM20040327A1 (it) * 2004-07-01 2004-10-01 Sigma Tau Ind Farmaceuti Uso della acetil l-carnitina per la preparazione di un medicamento per il trattamento del dolore neuropatico in pazienti diabetici.
US8569366B2 (en) * 2005-04-26 2013-10-29 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Acetyl L-carnitine for prevention of painful peripheral neuropathy in patients with type 2 diabetes
DK1874288T3 (da) * 2005-04-26 2013-08-26 Sigma Tau Ind Farmaceuti Acetyl L-carnitin til forebyggelse af smertefuld, perifer diabetisk neuropati
US20080161604A1 (en) * 2005-04-26 2008-07-03 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Acetyl L-Carnitine For Preventing Painful Peripheral Diabetic Neuropathy
JP2006347935A (ja) * 2005-06-15 2006-12-28 Masanori Ogata 炎症性サイトカインの産生が関与する疾患の予防及び／又は治療のための医薬
US8597640B2 (en) * 2007-10-31 2013-12-03 University Of Massachusetts Lowell Over-the-counter vitamin/nutriceutical formulation that provides neuroprotection and maintains or improves cognitive performance in alzheimer's disease and normal aging
SG185692A1 (en) 2010-06-16 2013-01-30 Sigma Tau Ind Farmaceuti Acetyl-carnitine for use in a method for increasing neurogenesis in neural tissue
US10413526B2 (en) 2015-03-31 2019-09-17 Kolinpharma S.P.A. Composition for the treatment of neuropathies and/or neuropathic pain
US10036011B2 (en) * 2016-02-11 2018-07-31 Qiagen Waltham, Inc. Scavenger compounds for improved sequencing-by-synthesis
EP4149437A1 (en) 2020-05-15 2023-03-22 Alfasigma S.p.A. Composition comprising methylfolate
EP4364730A1 (en) 2022-11-02 2024-05-08 Chiesi Italia S.p.A. Pharmaceutical composition comprising l-acetyl carnitine and beta-caryophyllene

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4346107A (en) * 1979-02-12 1982-08-24 Claudio Cavazza Pharmaceutical composition comprising acyl-carnitine for the treatment of impaired cerebral metabolism

Also Published As

Publication number Publication date
IT1196564B (it) 1988-11-16
US4751242A (en) 1988-06-14
DK403587D0 (da) 1987-08-03
DK164641C (da) 1992-12-14
EP0256999B1 (en) 1991-12-18
ATE70439T1 (de) 1992-01-15
JPS6344522A (ja) 1988-02-25
DK164641B (da) 1992-07-27
DE3775301D1 (de) 1992-01-30
EP0256999A3 (en) 1989-05-31
CA1298197C (en) 1992-03-31
ES2039262T3 (es) 1993-09-16
EP0256999A2 (en) 1988-02-24
IT8648358A0 (it) 1986-08-04
GR3003405T3 (en) 1993-02-17
JPH085786B2 (ja) 1996-01-24
DK403587A (da) 1988-02-05

Similar Documents

Publication Publication Date Title
EP0256999A3 (en) Use of acetyl l-carnitine in the therapeutical treatment of peripheral neuropathies
ES2052717T3 (es) Uso de derivados de indolona para la preparacion de medicamentos para el tratamiento de la enfermedad de parkinson.
CS545686A1 (en) Farmaceuticky prostredek a antihepatotoxickym pusobenim
HK1005847A1 (en) Use of acetyl l-carnitine in the therapeutic treatment of coma
ATE102830T1 (de) Methode zur behandlung des interstitiellen blasenentzuendung.
DK207889D0 (da) Farmaceutisk praeparat med anti-cancer virkning
ATE97001T1 (de) Topisch anzuwendende defibrotid enthaltende arzneizubereitungen.
EP0437929A3 (en) Use of diadenosine-5',5'''-p1,p4-tetraphosphate for the manufacture of a medicament for the treatment of heart disease
HK1004910A1 (en) Use of l-carnitine and acyl l-carnitines for treating patients suffering from aids-related syndromes and asymptomatic hiv-seropositive patients
IT1224250B (it) Associzione del depiprazolo con la morfina
ES2051864T3 (es) Un procedimiento para preparar una composicion farmaceutica con actividad anti-cancer.
KR930019207A (ko) 카르니틴 결핍 hiv-혈청양성 환자 치료용 l-카르니틴의 용도
OA09790A (en) "Paromomycin or its derivatives or salts thereof for parenteral treatment of human parasitic diseases".
ATE105192T1 (de) Methode fuer die kontrolle von chronischer atmungskrankheit und nekrotischer enteritis bei voegeln.
ZA897549B (en) Medicament for the treatment of diseases caused by retroviruses
IT1271354B (it) Preparazione di una forma farmaceutica atta a combattere l'iperinsulinismo contenente n-acetil cisteine e loro analoghi
RU92013625A (ru) Лекарственное средство, стимулирующее эритроидный росток кроветворения при цитостатических миелодепрессиях
RU92016264A (ru) Новые соединения, способ их получения, фармацевтический состав, его получение, способ профилактики или лечения, применение соединений