ZA875643B - Use of acetyl l-carnitine in the therapeutical treatment of peripheral neuropathies - Google Patents
Use of acetyl l-carnitine in the therapeutical treatment of peripheral neuropathiesInfo
- Publication number
- ZA875643B ZA875643B ZA875643A ZA875643A ZA875643B ZA 875643 B ZA875643 B ZA 875643B ZA 875643 A ZA875643 A ZA 875643A ZA 875643 A ZA875643 A ZA 875643A ZA 875643 B ZA875643 B ZA 875643B
- Authority
- ZA
- South Africa
- Prior art keywords
- carnitine
- acetyl
- peripheral neuropathies
- therapeutical treatment
- therapeutical
- Prior art date
Links
- RDHQFKQIGNGIED-MRVPVSSYSA-N O-acetyl-L-carnitine Chemical compound CC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C RDHQFKQIGNGIED-MRVPVSSYSA-N 0.000 title abstract 2
- 208000033808 peripheral neuropathy Diseases 0.000 title abstract 2
- 208000027232 peripheral nervous system disease Diseases 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 230000001154 acute effect Effects 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT48358/86A IT1196564B (it) | 1986-08-04 | 1986-08-04 | Impiego di acetil l-carnitina nel trattamento terapeutico delle neuropatie periferiche |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA875643B true ZA875643B (en) | 1988-11-30 |
Family
ID=11266089
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA875643A ZA875643B (en) | 1986-08-04 | 1987-07-30 | Use of acetyl l-carnitine in the therapeutical treatment of peripheral neuropathies |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4751242A (de) |
| EP (1) | EP0256999B1 (de) |
| JP (1) | JPH085786B2 (de) |
| AT (1) | ATE70439T1 (de) |
| CA (1) | CA1298197C (de) |
| DE (1) | DE3775301D1 (de) |
| DK (1) | DK164641C (de) |
| ES (1) | ES2039262T3 (de) |
| GR (1) | GR3003405T3 (de) |
| IT (1) | IT1196564B (de) |
| ZA (1) | ZA875643B (de) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1224842B (it) * | 1988-12-27 | 1990-10-24 | Sigma Tau Ind Farmaceuti | Uso di derivati della l-carnitina nel trattamento terapeutico delle alterazioni degenerative del sistema nervoso |
| US5641764A (en) * | 1989-03-31 | 1997-06-24 | Peter Maccallum Institute | Halogenated DNA ligand radiosensitizers for cancer therapy |
| IT1230141B (it) * | 1989-05-03 | 1991-10-14 | Fidia Spa | Impiego di derivati della fosfatidil carnitina per la preparazione di composizioni farmaceutiche aventi attivita' nella terapia delle patologie dell'uomo associate con un danno neuronale. |
| IT1244636B (it) * | 1991-01-04 | 1994-08-08 | Sigma Tau Ind Farmaceuti | Uso dell'acetil l-carnitina nel trattamento terapeutico del coma e composizioni farmaceutiche utili in tale trattamento. |
| IT1245699B (it) * | 1991-05-29 | 1994-10-14 | Sigma Tau Ind Farmaceuti | Derivati della l-carnitina quali agenti terapeutici per il trattamento delle miopatie, della degenarazione neuronale e per inibire la proteolisi |
| IT1263004B (it) * | 1992-10-08 | 1996-07-23 | Sigma Tau Ind Farmaceuti | Impiego della l-carnitina e acil l-carnitine nel trattamento a lungo termine di pazienti diabetici non insulino-dipendenti. |
| IT1276225B1 (it) * | 1995-10-17 | 1997-10-27 | Sigma Tau Ind Farmaceuti | Composizioni farmaceutiche contenenti l-carnitina e alcanoil l- carnitine in associazione con resveratrolo o suoi derivati utili per |
| IT1291127B1 (it) * | 1997-04-01 | 1998-12-29 | Sigma Tau Ind Farmaceuti | Integratore alimentare per soggetti dediti ad intensa e prolungata attivita' fisica |
| IT1294227B1 (it) * | 1997-08-01 | 1999-03-24 | Sigma Tau Ind Farmaceuti | Composizione farmaceutica contenente l-carnitina o una alcanoil l-carnitina e alcoli alifatici a lunga catena utile per la prevenzione |
| IT1298487B1 (it) * | 1997-12-19 | 2000-01-10 | Sigma Tau Ind Farmaceuti | Composizioni farmaceutiche comprendenti pentraxina lunga ptx3 per la terapia di patologie di tipo infettivo, infiammatorio o tumorale, |
| JPH11298323A (ja) | 1998-04-16 | 1999-10-29 | Nec Yamagata Ltd | 高速ロックアップｐｌｌ回路 |
| US20030199535A1 (en) * | 1998-07-30 | 2003-10-23 | Claudio Cavazza | Method for preventing and/or treating peripheral neuropathies induced by the administration of an anticancer agent |
| WO2000006134A2 (en) * | 1998-07-30 | 2000-02-10 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Use of l-carnitine and its alkanoyl derivatives in the preparation of medicaments with anticancer activity |
| IT1306178B1 (it) * | 1999-07-27 | 2001-05-30 | Sigma Tau Ind Farmaceuti | Uso della l-carnitina e dei suoi alcanoil derivati per la preparazionedi un medicamento utile nel trattamento del paziente affetto da |
| US6562869B1 (en) * | 1999-09-23 | 2003-05-13 | Juvenon, Inc. | Nutritional supplement for increased energy and stamina |
| AU7828200A (en) * | 1999-09-23 | 2001-04-24 | Juvenon Corporation | Nutritional supplement for increased energy and stamina |
| ITRM20010294A1 (it) * | 2001-05-29 | 2002-11-29 | Sigma Tau Ind Farmaceuti | Uso della acetil l-carnetina in associazione con la biotina per il trattamento di pazienti affetti da diabete mellito di tipo ii insulino re |
| ITRM20010293A1 (it) * | 2001-05-29 | 2002-11-29 | Sigma Tau Ind Farmaceuti | Uso della acetil-l-carnetina per la preparazione di un medicamento per la prevenzione del dolore. |
| US8173618B2 (en) * | 2003-07-25 | 2012-05-08 | University Of Massachusetts | Formulations for reducing neuronal degeneration |
| ITRM20040327A1 (it) * | 2004-07-01 | 2004-10-01 | Sigma Tau Ind Farmaceuti | Uso della acetil l-carnitina per la preparazione di un medicamento per il trattamento del dolore neuropatico in pazienti diabetici. |
| US8569366B2 (en) * | 2005-04-26 | 2013-10-29 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Acetyl L-carnitine for prevention of painful peripheral neuropathy in patients with type 2 diabetes |
| US20080161604A1 (en) * | 2005-04-26 | 2008-07-03 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Acetyl L-Carnitine For Preventing Painful Peripheral Diabetic Neuropathy |
| PT1874288E (pt) * | 2005-04-26 | 2013-08-28 | Sigma Tau Ind Farmaceuti | Acetil l-carnitina para prevenir a neuropatia diabética periférica dolorosa |
| JP2006347935A (ja) * | 2005-06-15 | 2006-12-28 | Masanori Ogata | 炎症性サイトカインの産生が関与する疾患の予防及び／又は治療のための医薬 |
| US8597640B2 (en) * | 2007-10-31 | 2013-12-03 | University Of Massachusetts Lowell | Over-the-counter vitamin/nutriceutical formulation that provides neuroprotection and maintains or improves cognitive performance in alzheimer's disease and normal aging |
| JP2013530170A (ja) | 2010-06-16 | 2013-07-25 | シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニ | 神経組織における神経発生を増大させるための方法における使用のためのアセチル−カルニチン |
| EP3277273B1 (de) | 2015-03-31 | 2020-02-26 | Kolinpharma S.p.A. | Zusammensetzungen zur behandlung von neuropathien und/oder neuropathischen schmerzen |
| US10036011B2 (en) * | 2016-02-11 | 2018-07-31 | Qiagen Waltham, Inc. | Scavenger compounds for improved sequencing-by-synthesis |
| CA3172190A1 (en) | 2020-05-15 | 2021-11-18 | Alfasigma S.P.A. | Composition comprising methylfolate |
| IT202200022437A1 (it) | 2022-11-02 | 2024-05-02 | Chiesi Italia S P A | Composizione farmaceutica comprendente l-acetilcarnitina e beta-cariofillene |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4346107A (en) * | 1979-02-12 | 1982-08-24 | Claudio Cavazza | Pharmaceutical composition comprising acyl-carnitine for the treatment of impaired cerebral metabolism |
-
1986
- 1986-08-04 IT IT48358/86A patent/IT1196564B/it active Protection Beyond IP Right Term
-
1987
- 1987-07-27 US US07/078,152 patent/US4751242A/en not_active Expired - Lifetime
- 1987-07-30 ZA ZA875643A patent/ZA875643B/xx unknown
- 1987-07-31 EP EP87830298A patent/EP0256999B1/de not_active Expired - Lifetime
- 1987-07-31 CA CA000543534A patent/CA1298197C/en not_active Expired - Lifetime
- 1987-07-31 AT AT87830298T patent/ATE70439T1/de not_active IP Right Cessation
- 1987-07-31 ES ES198787830298T patent/ES2039262T3/es not_active Expired - Lifetime
- 1987-07-31 DE DE8787830298T patent/DE3775301D1/de not_active Expired - Lifetime
- 1987-08-03 JP JP62194285A patent/JPH085786B2/ja not_active Expired - Lifetime
- 1987-08-03 DK DK403587A patent/DK164641C/da not_active IP Right Cessation
-
1991
- 1991-12-19 GR GR91401991T patent/GR3003405T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GR3003405T3 (en) | 1993-02-17 |
| IT8648358A0 (it) | 1986-08-04 |
| EP0256999B1 (de) | 1991-12-18 |
| CA1298197C (en) | 1992-03-31 |
| EP0256999A2 (de) | 1988-02-24 |
| DK164641B (da) | 1992-07-27 |
| EP0256999A3 (en) | 1989-05-31 |
| DK403587D0 (da) | 1987-08-03 |
| DE3775301D1 (de) | 1992-01-30 |
| US4751242A (en) | 1988-06-14 |
| JPH085786B2 (ja) | 1996-01-24 |
| ATE70439T1 (de) | 1992-01-15 |
| DK164641C (da) | 1992-12-14 |
| DK403587A (da) | 1988-02-05 |
| JPS6344522A (ja) | 1988-02-25 |
| ES2039262T3 (es) | 1993-09-16 |
| IT1196564B (it) | 1988-11-16 |
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