ZA874945B - Carbamate or urea derivatives,their preparation and pharmaceutical compositions comprising them - Google Patents

Carbamate or urea derivatives,their preparation and pharmaceutical compositions comprising them

Info

Publication number
ZA874945B
ZA874945B ZA874945A ZA874945A ZA874945B ZA 874945 B ZA874945 B ZA 874945B ZA 874945 A ZA874945 A ZA 874945A ZA 874945 A ZA874945 A ZA 874945A ZA 874945 B ZA874945 B ZA 874945B
Authority
ZA
South Africa
Prior art keywords
group
halogen atoms
carbamate
methyl
alkyl
Prior art date
Application number
ZA874945A
Other languages
English (en)
Inventor
Nigel Beeley
Beeley Nigel
Gerard Cremer
Cremer Gerard
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of ZA874945B publication Critical patent/ZA874945B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/40Y being a hydrogen or a carbon atom
    • C07C323/41Y being a hydrogen or an acyclic carbon atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/20Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
ZA874945A 1986-07-08 1987-07-07 Carbamate or urea derivatives,their preparation and pharmaceutical compositions comprising them ZA874945B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8609887A FR2601363B1 (fr) 1986-07-08 1986-07-08 (dimethylamino)-2 ethyl) ((((methylthio)-2 phenyl) (phenylmethyl)amino)-2 oxo-2 ethyl) carbamates ou urees, leur preparation et leur application en therapeutique.

Publications (1)

Publication Number Publication Date
ZA874945B true ZA874945B (en) 1988-02-24

Family

ID=9337176

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA874945A ZA874945B (en) 1986-07-08 1987-07-07 Carbamate or urea derivatives,their preparation and pharmaceutical compositions comprising them

Country Status (19)

Country Link
US (1) US4840967A (no)
EP (1) EP0252810B1 (no)
JP (1) JPS6323856A (no)
KR (1) KR880001587A (no)
AT (1) ATE62669T1 (no)
AU (1) AU595340B2 (no)
CA (1) CA1277330C (no)
CS (1) CS357891A3 (no)
DE (1) DE3769384D1 (no)
DK (1) DK349287A (no)
FI (1) FI85583C (no)
FR (1) FR2601363B1 (no)
GR (1) GR3002081T3 (no)
HU (1) HU196169B (no)
IL (1) IL83092A (no)
NO (1) NO164593C (no)
NZ (1) NZ220987A (no)
PT (1) PT85280B (no)
ZA (1) ZA874945B (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2641279B1 (fr) * 1989-01-03 1991-02-22 Synthelabo Derives de n-(amino-2 ethyl) n-(((methylthio-2 phenyl) (phenylmethyl)amino)-2 oxo ethyl)amides et carbamates, leur preparation et leur application en therapeutique
JPH02290464A (ja) * 1989-04-28 1990-11-30 Takagi Ind Co Ltd 瞬間湯沸器
EP0903341A1 (en) * 1997-07-22 1999-03-24 Akzo Nobel N.V. "Novel ortho-mercaptoaniline compounds"
CA2284864A1 (en) * 1998-01-21 1999-07-29 Zymogenetics, Inc. Dialkyl ureas as calcitonin mimetics
EP1466891A1 (en) * 2001-12-27 2004-10-13 Taisho Pharmaceutical Co., Ltd Carboxylic acid derivative
FR2885129B1 (fr) * 2005-04-29 2007-06-15 Proskelia Sas Nouveaux derives de l'ureee substituee parun thiazole ou benzothiazole, leur procede de preparation, leur application a titre de medicaments, les compositions pharmaceutiques les renfermant et utilisation.
WO2008073934A1 (en) * 2006-12-11 2008-06-19 Wyeth Ion channel modulators
AU2009282525A1 (en) * 2008-08-13 2010-02-18 Wntresearch Ab The use of Wnt5-a peptide derivates for the treatment of melanoma and gastric cancer
US9278119B2 (en) 2011-07-01 2016-03-08 Wntresearch Ab Treatment of prostate cancer and a method for determining the prognosis for prostate cancer patients
AU2015299055C1 (en) * 2014-08-06 2021-05-06 Ascendis Pharma A/S Prodrugs comprising an aminoalkyl glycine linker

Also Published As

Publication number Publication date
HU196169B (en) 1988-10-28
NZ220987A (en) 1989-12-21
JPS6323856A (ja) 1988-02-01
KR880001587A (ko) 1988-04-25
EP0252810A2 (fr) 1988-01-13
NO872832L (no) 1988-01-11
FI85583B (fi) 1992-01-31
EP0252810B1 (fr) 1991-04-17
AU595340B2 (en) 1990-03-29
HUT44482A (en) 1988-03-28
FI85583C (fi) 1992-05-11
US4840967A (en) 1989-06-20
FI873009A0 (fi) 1987-07-07
PT85280A (fr) 1987-08-01
ATE62669T1 (de) 1991-05-15
FR2601363A1 (fr) 1988-01-15
CA1277330C (en) 1990-12-04
DK349287D0 (da) 1987-07-07
NO164593B (no) 1990-07-16
GR3002081T3 (en) 1992-12-30
PT85280B (pt) 1990-03-30
NO872832D0 (no) 1987-07-07
AU7529487A (en) 1988-01-14
CS357891A3 (en) 1992-12-16
DK349287A (da) 1988-01-09
IL83092A (en) 1991-11-21
FR2601363B1 (fr) 1988-10-21
FI873009A (fi) 1988-01-09
IL83092A0 (en) 1987-12-31
NO164593C (no) 1990-10-24
DE3769384D1 (de) 1991-05-23
EP0252810A3 (en) 1988-09-07

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