ZA868829B - Carbapenems with quaternized heterothioalkylthio substitution at position 2 - Google Patents

Carbapenems with quaternized heterothioalkylthio substitution at position 2

Info

Publication number
ZA868829B
ZA868829B ZA868829A ZA868829A ZA868829B ZA 868829 B ZA868829 B ZA 868829B ZA 868829 A ZA868829 A ZA 868829A ZA 868829 A ZA868829 A ZA 868829A ZA 868829 B ZA868829 B ZA 868829B
Authority
ZA
South Africa
Prior art keywords
heterothioalkylthio
carbapenems
quaternized
substitution
quaternized heterothioalkylthio
Prior art date
Application number
ZA868829A
Other languages
English (en)
Inventor
Pierre Dextraze
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of ZA868829B publication Critical patent/ZA868829B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA868829A 1985-11-22 1986-11-21 Carbapenems with quaternized heterothioalkylthio substitution at position 2 ZA868829B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/800,867 US4880922A (en) 1985-11-22 1985-11-22 Carbapenems with quaternized heterothioalkylthio substitution at position 2

Publications (1)

Publication Number Publication Date
ZA868829B true ZA868829B (en) 1987-08-26

Family

ID=25179586

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA868829A ZA868829B (en) 1985-11-22 1986-11-21 Carbapenems with quaternized heterothioalkylthio substitution at position 2

Country Status (35)

Country Link
US (1) US4880922A (fi)
JP (1) JPS62195382A (fi)
KR (1) KR870004985A (fi)
CN (1) CN86107742A (fi)
AR (1) AR242209A1 (fi)
AT (1) AT397090B (fi)
AU (1) AU598767B2 (fi)
BE (1) BE905801A (fi)
CA (1) CA1273015A (fi)
CH (1) CH671020A5 (fi)
CS (1) CS259895B2 (fi)
DD (1) DD250710A5 (fi)
DE (1) DE3639762A1 (fi)
DK (1) DK560886A (fi)
EG (1) EG18111A (fi)
ES (1) ES2002914A6 (fi)
FI (1) FI83323C (fi)
FR (1) FR2590574B1 (fi)
GB (1) GB2183237B (fi)
GR (1) GR862786B (fi)
HU (1) HU197748B (fi)
IL (1) IL80694A0 (fi)
IT (1) IT1199669B (fi)
LU (1) LU86678A1 (fi)
MY (1) MY102954A (fi)
NL (1) NL8602964A (fi)
NO (1) NO164239C (fi)
NZ (1) NZ218296A (fi)
OA (1) OA08488A (fi)
PT (1) PT83797B (fi)
SE (1) SE469631B (fi)
SU (1) SU1614763A3 (fi)
YU (1) YU46030B (fi)
ZA (1) ZA868829B (fi)
ZW (1) ZW23486A1 (fi)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ219892A (en) * 1986-04-15 1991-02-26 Merck & Co Inc N-amino quaternised heteroarylium carbapenem derivatives and pharmaceutical compositions thereof
US5116833A (en) * 1990-10-19 1992-05-26 Bristol-Myers Squibb Company Antibiotic c-3 dithioacetal-substituted carbapenem compounds, compositions, and methods of use thereof
EP0507313A1 (en) * 1991-04-05 1992-10-07 Takeda Chemical Industries, Ltd. Polycyclic carbapenem compounds, their production and use
FR2920778B1 (fr) 2007-09-11 2009-10-30 Oreal Composes quinoliniums azoiques a motif disulfure/thiol, compositions les comprenant, procede de coloration de fibres keratiniques et dispositif.
FR2921382B1 (fr) 2007-09-21 2009-10-30 Oreal Colorant derive de phenyl-pyridol[1,2-a]indolium thiol-disulfure, composition tinctoriale comprenant ce colorant, procede d'eclaircissement des matieres keratiniques a partir de ce colorant
FR2921258A1 (fr) 2007-09-24 2009-03-27 Oreal Composition tinctoriale comprenant au moins un precurseur incolore disulfures/thiol, proced de coloration a partir de la composition

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4376774A (en) * 1979-05-29 1983-03-15 Merck & Co., Inc. Antibiotic N-heterocyclyl thienamycin
US4552696A (en) * 1982-04-09 1985-11-12 Bristol-Myers Company Carbapenem antibiotics
US4536335A (en) * 1982-06-18 1985-08-20 Bristol-Myers Company Carbapenem antibiotics
CA1269978A (en) * 1982-09-28 1990-06-05 Choung U. Kim Carbapenem antibiotics
AR241016A1 (es) * 1983-03-08 1991-04-30 Bristol Myeres Squibb Company "derivados de aminotiol cuaternario, procedimiento para prepararlos y procedimiento para preparar compuestos de carbapenem a partir de dichos derivados".
CA1273012A (en) * 1984-07-02 1990-08-21 Burton G. Christensen 1-methylcarbapenems having an externally alkylated mono- of bicyclic 2-quarternary heteroarylalkylthio substituent
CA1273011A (en) * 1984-07-02 1990-08-21 Susan M. Schmitt Carbapenems having an externally alkylated mono- or bicyclic 2-quaternary heteroarylalkylthio substituent
NZ219892A (en) * 1986-04-15 1991-02-26 Merck & Co Inc N-amino quaternised heteroarylium carbapenem derivatives and pharmaceutical compositions thereof

Also Published As

Publication number Publication date
NZ218296A (en) 1990-04-26
FR2590574A1 (fr) 1987-05-29
MY102954A (en) 1993-03-31
DD250710A5 (de) 1987-10-21
YU199486A (en) 1988-02-29
NO164239C (no) 1990-09-12
KR870004985A (ko) 1987-06-04
IT8622426A0 (it) 1986-11-21
PT83797B (pt) 1989-06-30
FI864714A0 (fi) 1986-11-19
LU86678A1 (fr) 1987-06-26
GB2183237B (en) 1989-11-08
CH671020A5 (fi) 1989-07-31
OA08488A (fr) 1988-07-29
US4880922A (en) 1989-11-14
GB8627913D0 (en) 1986-12-31
NO864669L (no) 1987-05-25
CS259895B2 (en) 1988-11-15
CN86107742A (zh) 1987-08-12
ATA313686A (de) 1993-06-15
NO864669D0 (no) 1986-11-21
GR862786B (en) 1987-03-24
IL80694A0 (en) 1987-02-27
CS843186A2 (en) 1988-03-15
BE905801A (fr) 1987-05-21
ES2002914A6 (es) 1988-10-01
DK560886D0 (da) 1986-11-21
IT8622426A1 (it) 1988-05-21
AU598767B2 (en) 1990-07-05
FI83323C (fi) 1991-06-25
AR242209A1 (es) 1993-03-31
FI83323B (fi) 1991-03-15
EG18111A (en) 1992-09-30
GB2183237A (en) 1987-06-03
YU46030B (sh) 1992-12-21
NL8602964A (nl) 1987-06-16
JPS62195382A (ja) 1987-08-28
AU6534386A (en) 1987-05-28
PT83797A (en) 1986-12-01
IT1199669B (it) 1988-12-30
FR2590574B1 (fr) 1989-07-28
CA1273015A (en) 1990-08-21
HU197748B (en) 1989-05-29
ZW23486A1 (en) 1987-04-29
NO164239B (no) 1990-06-05
SE8604990L (sv) 1987-05-23
DE3639762A1 (de) 1987-06-04
SE8604990D0 (sv) 1986-11-21
HUT42486A (en) 1987-07-28
SE469631B (sv) 1993-08-09
FI864714A (fi) 1987-05-23
AT397090B (de) 1994-01-25
SU1614763A3 (ru) 1990-12-15
DK560886A (da) 1987-05-23

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