ZA865119B - A method for producing small,spherical polymer particles - Google Patents

A method for producing small,spherical polymer particles

Info

Publication number
ZA865119B
ZA865119B ZA865119A ZA865119A ZA865119B ZA 865119 B ZA865119 B ZA 865119B ZA 865119 A ZA865119 A ZA 865119A ZA 865119 A ZA865119 A ZA 865119A ZA 865119 B ZA865119 B ZA 865119B
Authority
ZA
South Africa
Prior art keywords
polymer particles
spherical polymer
producing small
phase
droplets
Prior art date
Application number
ZA865119A
Other languages
English (en)
Inventor
Bo Magnus Ekman
Ake Rikard Lindahl
Original Assignee
Bo Magnus Ekman
Ake Rikard Lindahl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bo Magnus Ekman, Ake Rikard Lindahl filed Critical Bo Magnus Ekman
Publication of ZA865119B publication Critical patent/ZA865119B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/12—Powdering or granulating
    • C08J3/14—Powdering or granulating by precipitation from solutions
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/12—Powdering or granulating
    • C08J3/16—Powdering or granulating by coagulating dispersions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Medicinal Preparation (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Peptides Or Proteins (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Compounds Of Alkaline-Earth Elements, Aluminum Or Rare-Earth Metals (AREA)
ZA865119A 1985-07-12 1986-07-09 A method for producing small,spherical polymer particles ZA865119B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8503459A SE459005B (sv) 1985-07-12 1985-07-12 Saett att framstaella sfaeriska polymerpartiklar

Publications (1)

Publication Number Publication Date
ZA865119B true ZA865119B (en) 1987-03-25

Family

ID=20360901

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA865119A ZA865119B (en) 1985-07-12 1986-07-09 A method for producing small,spherical polymer particles

Country Status (14)

Country Link
US (1) US4822535A (xx)
EP (1) EP0213303B1 (xx)
JP (1) JPS6264863A (xx)
AT (1) ATE66947T1 (xx)
AU (1) AU582865B2 (xx)
CA (1) CA1278227C (xx)
DE (1) DE3681230D1 (xx)
DK (1) DK168575B1 (xx)
FI (1) FI82475C (xx)
IE (1) IE58857B1 (xx)
IL (1) IL79292A (xx)
NO (1) NO165596C (xx)
SE (1) SE459005B (xx)
ZA (1) ZA865119B (xx)

Families Citing this family (165)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6024983A (en) * 1986-10-24 2000-02-15 Southern Research Institute Composition for delivering bioactive agents for immune response and its preparation
FR2606419B1 (fr) * 1986-11-07 1994-04-01 Commissariat A Energie Atomique Procede de fabrication d'une composition ferromagnetique, cristal liquide ferromagnetique obtenu par ce procede et dispositif utilisant ce cristal liquide
US5102983A (en) * 1990-04-02 1992-04-07 United States Surgical Corporation Process for preparing foamed, bioabsorbable polymer particles
SE9002339L (sv) * 1990-07-04 1992-01-05 Kabi Pharmacia Ab Terapeutisk komposition och foerfarande foer dess framstaellning
US5529914A (en) 1990-10-15 1996-06-25 The Board Of Regents The Univeristy Of Texas System Gels for encapsulation of biological materials
US5342557A (en) * 1990-11-27 1994-08-30 United States Surgical Corporation Process for preparing polymer particles
DE4038887A1 (de) * 1990-12-06 1992-07-02 Lohmann Therapie Syst Lts Verfahren zur herstellung von kollagenpartikeln und ihre verwendung als wirkstofftraeger
US5616311A (en) * 1991-01-15 1997-04-01 Hemosphere, Inc. Non-crosslinked protein particles for therapeutic and diagnostic use
US6391343B1 (en) 1991-01-15 2002-05-21 Hemosphere, Inc. Fibrinogen-coated particles for therapeutic use
US5725804A (en) * 1991-01-15 1998-03-10 Hemosphere, Inc. Non-crosslinked protein particles for therapeutic and diagnostic use
WO1996039128A1 (en) * 1995-06-06 1996-12-12 Hemosphere, Inc. Protein particles for therapeutic and diagnostic use
US5143662A (en) * 1991-02-12 1992-09-01 United States Surgical Corporation Process for preparing particles of bioabsorbable polymer
GB9116610D0 (en) * 1991-08-01 1991-09-18 Danbiosyst Uk Preparation of microparticles
AU3124793A (en) 1991-10-29 1993-06-07 Clover Consolidated, Limited Crosslinkable polysaccharides, polycations and lipids useful for encapsulation and drug release
US5525519A (en) * 1992-01-07 1996-06-11 Middlesex Sciences, Inc. Method for isolating biomolecules from a biological sample with linear polymers
JPH0778126B2 (ja) * 1992-02-10 1995-08-23 日清紡績株式会社 多糖類真球状粒子及び製造方法
US5573934A (en) * 1992-04-20 1996-11-12 Board Of Regents, The University Of Texas System Gels for encapsulation of biological materials
EP0644771B2 (en) † 1992-06-11 2006-12-06 Alkermes Controlled Therapeutics, Inc. Erythropoietin drug delivery system
AU4693093A (en) * 1992-07-27 1994-02-14 Haemacure Biotech Inc. Biocompatible surgical implant
US5439686A (en) * 1993-02-22 1995-08-08 Vivorx Pharmaceuticals, Inc. Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor
US5665382A (en) * 1993-02-22 1997-09-09 Vivorx Pharmaceuticals, Inc. Methods for the preparation of pharmaceutically active agents for in vivo delivery
US6753006B1 (en) 1993-02-22 2004-06-22 American Bioscience, Inc. Paclitaxel-containing formulations
US5916596A (en) * 1993-02-22 1999-06-29 Vivorx Pharmaceuticals, Inc. Protein stabilized pharmacologically active agents, methods for the preparation thereof and methods for the use thereof
US5997904A (en) * 1993-02-22 1999-12-07 American Bioscience, Inc. Total nutrient admixtures as stable multicomponent liquids or dry powders and methods for the preparation thereof
US5650156A (en) * 1993-02-22 1997-07-22 Vivorx Pharmaceuticals, Inc. Methods for in vivo delivery of nutriceuticals and compositions useful therefor
US6528067B1 (en) 1993-02-22 2003-03-04 American Bioscience, Inc. Total nutrient admixtures as stable multicomponent liquids or dry powders and methods for the preparation thereof
CA2155947C (en) * 1993-02-22 2007-08-21 Mark W. Grinstaff Methods for in vivo delivery of biologics and compositions useful therefor
US6090925A (en) 1993-03-09 2000-07-18 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
US5554730A (en) * 1993-03-09 1996-09-10 Middlesex Sciences, Inc. Method and kit for making a polysaccharide-protein conjugate
DK0809110T3 (da) * 1993-03-09 2004-05-24 Baxter Int Makromolekylære mikropartikler og fremgangsmåder til fremstilling
US5549908A (en) * 1993-05-20 1996-08-27 The University Of Akron Hydrolytically labile microspheres of polysaccharide crosslinked with cyanogen halide and their application in wound dressings
US5827707A (en) * 1995-06-07 1998-10-27 Neocrin Company Method for manufacturing minimal volume capsules containing biological materials
SE505146C2 (sv) * 1995-10-19 1997-06-30 Biogram Ab Partiklar för fördröjd frisättning
US5922403A (en) * 1996-03-12 1999-07-13 Tecle; Berhan Method for isolating ultrafine and fine particles
US6652837B1 (en) 1996-05-24 2003-11-25 Massachusetts Institute Of Technology Preparation of novel particles for inhalation
US5874064A (en) 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US5985309A (en) * 1996-05-24 1999-11-16 Massachusetts Institute Of Technology Preparation of particles for inhalation
US8137684B2 (en) 1996-10-01 2012-03-20 Abraxis Bioscience, Llc Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
WO1998022093A1 (en) * 1996-11-19 1998-05-28 Octoplus B.V. Process for the preparation of a controlled release system
EP0842657A1 (en) * 1996-11-19 1998-05-20 OctoPlus B.V. Microspheres for controlled release and processes to prepare these microspheres
US6395302B1 (en) * 1996-11-19 2002-05-28 Octoplus B.V. Method for the preparation of microspheres which contain colloidal systems
JP2002503254A (ja) 1997-06-05 2002-01-29 ヘモスフィア，インコーポレイテッド フィブリノゲンをコーティングしたミクロスフィア
SE512663C2 (sv) * 1997-10-23 2000-04-17 Biogram Ab Inkapslingsförfarande för aktiv substans i en bionedbrytbar polymer
DE19839212C2 (de) * 1998-08-28 2002-05-23 Celanese Ventures Gmbh Verfahren zur Herstellung von sphärischen Nanopartikeln, die ganz oder teilweise aus mindestens einem wasserunlöslichen linearen Polysaccharid bestehen
US20070212422A1 (en) * 1999-11-10 2007-09-13 Manfred Keller Dry powder for inhalation
EP1074248A1 (en) * 1999-07-08 2001-02-07 Arnold Hilgers Delivery system for biological material
US6749835B1 (en) 1999-08-25 2004-06-15 Advanced Inhalation Research, Inc. Formulation for spray-drying large porous particles
US7678364B2 (en) 1999-08-25 2010-03-16 Alkermes, Inc. Particles for inhalation having sustained release properties
US6699470B1 (en) * 1999-10-12 2004-03-02 Massachusetts Institute Of Technology Mesh-gel constructs for cell delivery containing enzymes and/or enzyme inhibitors to control gel degradation
US6805879B2 (en) * 2000-06-23 2004-10-19 Biopharm Solutions Inc. Stable polymer aqueous/aqueous emulsion system and uses thereof
AU2001294459A1 (en) 2000-10-06 2002-04-15 Jagotec Ag A controlled-release, parenterally administrable microparticle preparation
SE517422C2 (sv) 2000-10-06 2002-06-04 Bioglan Ab Farmaceutiskt acceptabel stärkelse
SE517421C2 (sv) 2000-10-06 2002-06-04 Bioglan Ab Mikropartiklar, lämpade för parenteral administration, väsentligen bestående av stärkelse med minst 85 % amylopektin och med reducerad molekylvikt, samt framställning därav
EP1333814A1 (en) * 2000-11-16 2003-08-13 Jagotec Ag Parenterally administrable microparticles
SE518008C2 (sv) * 2000-11-16 2002-08-13 Bioglan Ab Parenteralt administrerbara mikropartiklar och förfarande för framställning av desamma
SE518007C2 (sv) 2000-11-16 2002-08-13 Bioglan Ab Förfarande för framställning av mikropartiklar
JP2005504715A (ja) 2000-12-29 2005-02-17 アドバンスト インハレーション リサーチ，インコーポレイテッド 持続放出特性を有する吸入用粒子
US6743462B1 (en) * 2001-05-31 2004-06-01 Advanced Cardiovascular Systems, Inc. Apparatus and method for coating implantable devices
US6695920B1 (en) 2001-06-27 2004-02-24 Advanced Cardiovascular Systems, Inc. Mandrel for supporting a stent and a method of using the mandrel to coat a stent
US7105181B2 (en) 2001-10-05 2006-09-12 Jagotec, Ag Microparticles
SE0201599D0 (sv) 2002-03-21 2002-05-30 Skyepharma Ab Microparticles
US7094369B2 (en) * 2002-03-29 2006-08-22 Scimed Life Systems, Inc. Processes for manufacturing polymeric microspheres
US7131997B2 (en) * 2002-03-29 2006-11-07 Scimed Life Systems, Inc. Tissue treatment
US7462366B2 (en) 2002-03-29 2008-12-09 Boston Scientific Scimed, Inc. Drug delivery particle
US7053134B2 (en) 2002-04-04 2006-05-30 Scimed Life Systems, Inc. Forming a chemically cross-linked particle of a desired shape and diameter
US7718099B2 (en) 2002-04-25 2010-05-18 Tosoh Corporation Fine channel device, fine particle producing method and solvent extraction method
WO2003105917A2 (en) 2002-06-12 2003-12-24 Scimed Life Systems, Inc. Bulking agents
FR2843302B1 (fr) * 2002-08-09 2004-10-22 Centre Nat Rech Scient Forme galenique pour la delivrance colique de principes actifs
FR2843301B1 (fr) * 2002-08-09 2004-10-22 Centre Nat Rech Scient Forme galenique pour la delivrance colique de principes actifs
US7842377B2 (en) 2003-08-08 2010-11-30 Boston Scientific Scimed, Inc. Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
US7449236B2 (en) * 2002-08-09 2008-11-11 Boston Scientific Scimed, Inc. Porous polymeric particle comprising polyvinyl alcohol and having interior to surface porosity-gradient
US8012454B2 (en) * 2002-08-30 2011-09-06 Boston Scientific Scimed, Inc. Embolization
US7883490B2 (en) * 2002-10-23 2011-02-08 Boston Scientific Scimed, Inc. Mixing and delivery of therapeutic compositions
US7588825B2 (en) * 2002-10-23 2009-09-15 Boston Scientific Scimed, Inc. Embolic compositions
US7074276B1 (en) 2002-12-12 2006-07-11 Advanced Cardiovascular Systems, Inc. Clamp mandrel fixture and a method of using the same to minimize coating defects
WO2004066704A2 (en) * 2003-01-17 2004-08-12 Cornell Research Foundation, Inc. Injectable hydrogel microspheres from aqueous two-phase system
SE0301431D0 (sv) 2003-05-19 2003-05-19 Dermagen Novel antimicrobial peptides
US7976823B2 (en) * 2003-08-29 2011-07-12 Boston Scientific Scimed, Inc. Ferromagnetic particles and methods
US7901770B2 (en) * 2003-11-04 2011-03-08 Boston Scientific Scimed, Inc. Embolic compositions
WO2005052060A1 (ja) 2003-11-28 2005-06-09 Daicel Chemical Industries, Ltd. 分散体及び着色された有機固体粒子の製造方法
US7736671B2 (en) * 2004-03-02 2010-06-15 Boston Scientific Scimed, Inc. Embolization
EP1576952A1 (en) * 2004-03-18 2005-09-21 OctoPlus Technologies B.V. Hydrogel microspheres with improved release profile
US8173176B2 (en) 2004-03-30 2012-05-08 Boston Scientific Scimed, Inc. Embolization
US20050238870A1 (en) * 2004-04-22 2005-10-27 Marcia Buiser Embolization
US7311861B2 (en) * 2004-06-01 2007-12-25 Boston Scientific Scimed, Inc. Embolization
US8425550B2 (en) * 2004-12-01 2013-04-23 Boston Scientific Scimed, Inc. Embolic coils
US7858183B2 (en) * 2005-03-02 2010-12-28 Boston Scientific Scimed, Inc. Particles
US7727555B2 (en) * 2005-03-02 2010-06-01 Boston Scientific Scimed, Inc. Particles
US7963287B2 (en) * 2005-04-28 2011-06-21 Boston Scientific Scimed, Inc. Tissue-treatment methods
US8017152B2 (en) * 2005-05-27 2011-09-13 Stratosphere Pharma Ab Cores and microcapsules suitable for parenteral administration as well as process for their manufacture
US20070004973A1 (en) * 2005-06-15 2007-01-04 Tan Sharon M L Tissue treatment methods
US7622070B2 (en) 2005-06-20 2009-11-24 Advanced Cardiovascular Systems, Inc. Method of manufacturing an implantable polymeric medical device
US9463426B2 (en) * 2005-06-24 2016-10-11 Boston Scientific Scimed, Inc. Methods and systems for coating particles
US7823533B2 (en) 2005-06-30 2010-11-02 Advanced Cardiovascular Systems, Inc. Stent fixture and method for reducing coating defects
WO2007028457A1 (en) * 2005-07-25 2007-03-15 Unilever Plc Method of producing fine particles
US7735449B1 (en) 2005-07-28 2010-06-15 Advanced Cardiovascular Systems, Inc. Stent fixture having rounded support structures and method for use thereof
US8007509B2 (en) * 2005-10-12 2011-08-30 Boston Scientific Scimed, Inc. Coil assemblies, components and methods
US20070083219A1 (en) * 2005-10-12 2007-04-12 Buiser Marcia S Embolic coil introducer sheath locking mechanisms
US20070142859A1 (en) * 2005-12-19 2007-06-21 Boston Scientific Scimed, Inc. Embolic coils
US8152839B2 (en) * 2005-12-19 2012-04-10 Boston Scientific Scimed, Inc. Embolic coils
US7867547B2 (en) 2005-12-19 2011-01-11 Advanced Cardiovascular Systems, Inc. Selectively coating luminal surfaces of stents
US8101197B2 (en) 2005-12-19 2012-01-24 Stryker Corporation Forming coils
US7501179B2 (en) * 2005-12-21 2009-03-10 Boston Scientific Scimed, Inc. Block copolymer particles
US7947368B2 (en) * 2005-12-21 2011-05-24 Boston Scientific Scimed, Inc. Block copolymer particles
US20070142560A1 (en) * 2005-12-21 2007-06-21 Young-Ho Song Block copolymer particles
GB0602897D0 (en) * 2006-02-13 2006-03-22 Jagotec Ag Improvements In Or Relating To Dry Powder Inhaler Devices
US8069814B2 (en) 2006-05-04 2011-12-06 Advanced Cardiovascular Systems, Inc. Stent support devices
US7985441B1 (en) 2006-05-04 2011-07-26 Yiwen Tang Purification of polymers for coating applications
CA2651990C (en) 2006-05-16 2014-12-23 Dermagen Ab Improved antimicrobial peptides
US20070299461A1 (en) * 2006-06-21 2007-12-27 Boston Scientific Scimed, Inc. Embolic coils and related components, systems, and methods
US8414927B2 (en) 2006-11-03 2013-04-09 Boston Scientific Scimed, Inc. Cross-linked polymer particles
GB0622818D0 (en) * 2006-11-15 2006-12-27 Jagotec Ag Improvements in or relating to organic compounds
US8273376B2 (en) 2006-11-17 2012-09-25 Da Volterra Colonic delivery of metallo-dependent enzymes
US20080145658A1 (en) * 2006-12-15 2008-06-19 Boston Scientific Scimed, Inc. Freeze Thaw Methods For Making Polymer Particles
GB0625303D0 (en) * 2006-12-19 2007-01-24 Jagotec Ag Improvements in and relating to metered dose inhalers
NL1033621C2 (nl) * 2007-03-30 2008-10-06 Friesland Brands Bv Encapsuleren met behulp van een dubbele suspensie.
NL2002049C (nl) * 2008-10-01 2010-04-02 Friesland Brands Bv Encapsuleren met behulp van een dubbele suspensie.
GB2472856B (en) 2009-08-21 2012-07-11 Cantargia Ab IL1-RAP modulators and uses thereof
GB0916576D0 (en) 2009-09-22 2009-10-28 Malmsten Nils M Polypeptides and uses thereof
GB0916578D0 (en) 2009-09-22 2009-10-28 Malmsten Nils M Polypeptides and uses thereof
AU2012208379B2 (en) 2011-01-19 2017-04-20 Cantargia Ab Anti - IL1RAP antibodies and their use for treating human
GB2493540A (en) 2011-08-10 2013-02-13 Follicum Ab Agents for stimulating hair growth in mammals
GB201115280D0 (en) 2011-09-05 2011-10-19 Alligator Bioscience Ab Antibodies, uses and methods
MX353964B (es) 2011-10-28 2018-02-06 Fredax Ab Agentes terapeuticos y usos de los mismos.
GB201214169D0 (en) 2012-08-08 2012-09-19 Biostatus Ltd New compounds and uses thereof
CA2930493A1 (en) 2013-11-19 2015-05-28 Fredax Ab Humanised anti kallikrein-2 antibody
EP3099317B1 (en) 2014-01-29 2021-08-04 Enzymatica AB Cod trypsin for use in the treatment of microbial infections in a subject with immunodeficiency
GB201405784D0 (en) 2014-03-31 2014-05-14 Enzymatica Ab Novel methods, polypeptides and uses thereof
GB201403875D0 (en) 2014-03-05 2014-04-16 Cantargia Ab Novel antibodies and uses thereof
GB201413913D0 (en) 2014-08-06 2014-09-17 Cantargia Ab Novel antibodies and uses thereof
CA2970034C (en) * 2014-12-18 2019-09-03 Avantium Knowledge Centre B.V. Process for the production of solid saccharides from an aqueous saccharide solution
EP3120866A1 (en) 2015-07-24 2017-01-25 Zymetech ehf. Use of marine serine proteases for removal, prevention and inhibition of formation and growth of biofilms
US11332543B2 (en) 2015-10-05 2022-05-17 Fredax Ab Antibody polypeptides and uses thereof
GB201601136D0 (en) 2016-01-21 2016-03-09 Mörgelin Matthias And Abdillahi Suado M Novel polypeptides and medical uses thereof
CA3021618A1 (en) 2016-04-22 2017-10-26 Alligator Bioscience Ab Novel bispecific polypeptides against cd137
GB201611530D0 (en) 2016-07-01 2016-08-17 Alligator Bioscience Ab Novel polypeptides
GB201619648D0 (en) 2016-11-21 2017-01-04 Alligator Bioscience Ab Novel antibodies and uses thereof
GB201701315D0 (en) 2017-01-26 2017-03-15 Enzymatica Ab Novel treatments
CA3070272A1 (en) 2017-07-20 2019-01-24 Aptevo Research And Development Llc Antigen binding proteins binding to 5t4 and 4-1bb and related compositions and methods
GB201800274D0 (en) 2018-01-08 2018-02-21 Enzymatica Ab Novel treatments
GB201801982D0 (en) 2018-02-07 2018-03-28 Enzymatica Ab Novel treatments
US20220064325A1 (en) 2018-12-17 2022-03-03 Alligator Bioscience Ab Novel polypeptides
EP3898681A2 (en) 2018-12-17 2021-10-27 Alligator Bioscience AB Polypeptides
GB201909298D0 (en) 2019-06-28 2019-08-14 Colzyx Ab Novel compositions and uses thereof
EP4069374A1 (en) 2019-12-06 2022-10-12 Thoas Fioretos Novel agents and uses thereof
KR102350655B1 (ko) 2020-10-13 2022-01-12 인센 주식회사 테스토스테론-특이적 어피바디 및 이의 용도
GB202016456D0 (en) 2020-10-16 2020-12-02 Colzyx Ab Novel bioactive peptide combinations and uses thereof
GB202018187D0 (en) 2020-11-19 2021-01-06 Univ Southampton Compositions
JP2024500920A (ja) 2020-12-23 2024-01-10 カンタージア アクチエボラーグ 抗ｉｌ１ｒａｐ抗体
GB2603166A (en) 2021-01-29 2022-08-03 Thelper As Therapeutic and Diagnostic Agents and Uses Thereof
GB202102709D0 (en) 2021-02-25 2021-04-14 Univ Southampton Compounds
GB202102823D0 (en) 2021-02-26 2021-04-14 Tochikunda Ltd Diagnostic method
WO2022189518A1 (en) 2021-03-09 2022-09-15 Novalysin Ab Antibacterial polypeptides
EP4355780A1 (en) 2021-06-18 2024-04-24 Alligator Bioscience AB Novel combination therapies and uses thereof
CN113786392A (zh) * 2021-09-30 2021-12-14 四川大学 一种纳米颗粒及其制备方法和应用
EP4426733A2 (en) 2021-11-05 2024-09-11 Alligator Bioscience AB Novel peptides
GB202201137D0 (en) 2022-01-28 2022-03-16 Thelper As Therapeutic and diagnostic agents and uses thereof
AU2023227393A1 (en) 2022-03-03 2024-10-17 Targinta Ab Integrin alpha10 antibody
WO2023247050A1 (en) 2022-06-23 2023-12-28 Alligator Bioscience Ab Combination therapies
GB202210965D0 (en) 2022-07-27 2022-09-07 Alligator Bioscience Ab Novel dosages
GB202210957D0 (en) 2022-07-27 2022-09-07 Alligator Bioscience Ab Novel dosages
GB202212184D0 (en) 2022-08-22 2022-10-05 Univ Southampton Compounds
GB202215115D0 (en) 2022-10-13 2022-11-30 Univ Nottingham VEGF antibodies
WO2024194166A1 (en) 2023-03-17 2024-09-26 Novo Nordisk A/S Biological methods
WO2024213533A1 (en) 2023-04-13 2024-10-17 Alligator Bioscience Ab Combination therapies

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL262192A (xx) * 1960-03-09
SE358894B (xx) * 1961-10-25 1973-08-13 Pharmacia Ab
US3155590A (en) * 1962-08-02 1964-11-03 Ncr Co Encapsulation process and its product
US3657144A (en) * 1967-06-05 1972-04-18 Ncr Co Encapsulation process
SE343306B (sv) * 1969-02-07 1972-03-06 Pharmacia Fine Chemicals Ab Saett att framstaella jonbytare bestaende av runda korn av substituerad cellulosa
US3897414A (en) * 1969-09-12 1975-07-29 Pharmacia Fine Chemicals Ab Method of fractionating a mixture of high molecular substances of different physical characteristics
US4061466A (en) * 1974-10-16 1977-12-06 Ingvar Gosta Holger Sjoholm Biologically active composition and the use thereof
US4123403A (en) * 1977-06-27 1978-10-31 The Dow Chemical Company Continuous process for preparing aqueous polymer microsuspensions
SE7812237L (sv) * 1978-11-28 1980-05-29 Pharmacia Diagnostics Ab Koncentrationsbestemning av substanser med formaga att biospecifikt binda molekyler med biologiskt ursprung
DE3013839A1 (de) * 1979-04-13 1980-10-30 Freunt Ind Co Ltd Verfahren zur herstellung einer aktivierten pharmazeutischen zusammensetzung
JPS5927610B2 (ja) * 1979-12-24 1984-07-06 工業技術院長 マイクロカプセルの製造方法
IT1148784B (it) * 1980-04-09 1986-12-03 Eurand Spa Procedimento per la preparazione di microcapsule in un veicolo liquido
US4389330A (en) * 1980-10-06 1983-06-21 Stolle Research And Development Corporation Microencapsulation process
JPS57197214A (en) * 1981-05-29 1982-12-03 Tanabe Seiyaku Co Ltd Rapid-releasing microcapsule and its preparation
US4606940A (en) * 1984-12-21 1986-08-19 The Ohio State University Research Foundation Small particle formation and encapsulation

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SE8503459L (sv) 1987-01-13
FI82475B (fi) 1990-11-30
DK330186D0 (da) 1986-07-11
IL79292A (en) 1991-06-10
AU5922486A (en) 1987-01-15
CA1278227C (en) 1990-12-27
FI862925A0 (fi) 1986-07-11
NO165596B (no) 1990-11-26
JPS6264863A (ja) 1987-03-23
NO862830D0 (no) 1986-07-11
DE3681230D1 (de) 1991-10-10
IE58857B1 (en) 1993-11-17
ATE66947T1 (de) 1991-09-15
EP0213303A2 (en) 1987-03-11
IL79292A0 (en) 1986-09-30
SE459005B (sv) 1989-05-29
NO862830L (no) 1987-01-13
IE861728L (en) 1987-01-12
DK330186A (da) 1987-01-13
EP0213303B1 (en) 1991-09-04
EP0213303A3 (en) 1988-07-20
US4822535A (en) 1989-04-18
DK168575B1 (da) 1994-04-25
NO165596C (no) 1991-03-06
FI82475C (fi) 1991-03-11
FI862925A (fi) 1987-01-13
AU582865B2 (en) 1989-04-13
SE8503459D0 (sv) 1985-07-12
JPH0564974B2 (xx) 1993-09-16

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