ZA856403B - Tricyclic oxindole antiinflammatory agents - Google Patents

Tricyclic oxindole antiinflammatory agents

Info

Publication number
ZA856403B
ZA856403B ZA856403A ZA856403A ZA856403B ZA 856403 B ZA856403 B ZA 856403B ZA 856403 A ZA856403 A ZA 856403A ZA 856403 A ZA856403 A ZA 856403A ZA 856403 B ZA856403 B ZA 856403B
Authority
ZA
South Africa
Prior art keywords
sub
antiinflammatory agents
oxindole
tricyclic
tricyclic oxindole
Prior art date
Application number
ZA856403A
Other languages
English (en)
Inventor
Lawrence Sherman Melvin Jr
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA856403B publication Critical patent/ZA856403B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/58[b]- or [c]-condensed
    • C07D209/70[b]- or [c]-condensed containing carbocyclic rings other than six-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Optical Fibers, Optical Fiber Cores, And Optical Fiber Bundles (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Filling Or Discharging Of Gas Storage Vessels (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Medicinal Preparation (AREA)
ZA856403A 1984-08-24 1985-08-23 Tricyclic oxindole antiinflammatory agents ZA856403B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1984/001371 WO1986001510A1 (en) 1984-08-24 1984-08-24 Tricyclic oxindole antiinflammatory agents

Publications (1)

Publication Number Publication Date
ZA856403B true ZA856403B (en) 1987-04-29

Family

ID=22182243

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA856403A ZA856403B (en) 1984-08-24 1985-08-23 Tricyclic oxindole antiinflammatory agents

Country Status (21)

Country Link
US (1) US4695571A (de)
EP (1) EP0173520B1 (de)
JP (1) JPS6157554A (de)
KR (1) KR870001144B1 (de)
AT (1) ATE49211T1 (de)
AU (1) AU553859B2 (de)
CA (1) CA1244427A (de)
DE (1) DE3575140D1 (de)
DK (1) DK160098C (de)
EG (1) EG17287A (de)
ES (2) ES8704497A1 (de)
FI (1) FI79319C (de)
GR (1) GR852026B (de)
HU (2) HU203350B (de)
IE (1) IE58739B1 (de)
IL (1) IL76175A (de)
PH (1) PH23065A (de)
PL (2) PL147395B1 (de)
PT (1) PT81004B (de)
WO (1) WO1986001510A1 (de)
ZA (1) ZA856403B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3531678A1 (de) * 1985-09-05 1987-03-12 Boehringer Mannheim Gmbh Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
JPS63223492A (ja) * 1987-03-11 1988-09-16 Okawara Mfg Co Ltd 熱交換器
WO1990008145A1 (en) * 1989-01-10 1990-07-26 Pfizer Inc. Anti-inflammatory 1-heteroaryl-3-acyl-2-oxindoles
US5128352A (en) * 1989-01-10 1992-07-07 Pfizer Inc. Anti-inflammatory 1-heteroaryl-oxindole-3-carboxamides
US5300655A (en) * 1989-04-18 1994-04-05 Pfizer Inc. 2-carboxy-thiophene derivatives
US5047554A (en) * 1989-04-18 1991-09-10 Pfizer Inc. 3-substituted-2-oxindole derivatives
JPH04217684A (ja) * 1990-05-30 1992-08-07 Shionogi & Co Ltd アルド−ス還元酵素阻害物質
DE4027592A1 (de) * 1990-08-31 1992-03-05 Beiersdorf Ag Neue pyrrolobenzimidazole, imidazobenzoxazinone und imidazochinolone, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen
ATE445838T1 (de) 2001-07-25 2009-10-15 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
WO2005041957A1 (en) * 2003-10-29 2005-05-12 Pfizer Products Inc. Oxindole derivatives and their use as phosphodiesterase type 2 inhibitors
EP2671508B1 (de) 2005-04-28 2020-09-16 Proteus Digital Health, Inc. Pharma-Informatiksystem
CA2663377A1 (en) 2006-09-18 2008-03-27 Raptor Pharmaceutical Inc. Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
HUE059078T2 (hu) 2009-02-20 2022-10-28 Enhanx Biopharm Inc Glutation-alapú hatóanyagszállító rendszer
JP2012526144A (ja) 2009-05-06 2012-10-25 ラボラトリー スキン ケア インコーポレイテッド 活性物質−リン酸カルシウム粒子複合体を含む経皮送達組成物およびその使用方法
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE756447A (fr) * 1969-10-15 1971-03-22 Pfizer Oxindolecarboxamides
US3749731A (en) * 1971-07-08 1973-07-31 Warner Lambert Co 2-oxo-n-(2-thiazolyl)-3-indoline-carboxamide
US4644005A (en) * 1984-10-31 1987-02-17 Pfizer Inc. Oxindole antiinflammatory agents

Also Published As

Publication number Publication date
GR852026B (de) 1985-12-19
IE852081L (en) 1986-02-24
HUT47580A (en) 1989-03-28
DK382685D0 (da) 1985-08-23
PT81004A (en) 1985-09-01
FI861704A (fi) 1986-04-23
ES8704497A1 (es) 1987-04-01
IE58739B1 (en) 1993-11-03
HU203238B (en) 1991-06-28
IL76175A (en) 1989-08-15
PL147393B1 (en) 1989-05-31
EP0173520A2 (de) 1986-03-05
US4695571A (en) 1987-09-22
PL147395B1 (en) 1989-05-31
CA1244427A (en) 1988-11-08
PL255089A1 (en) 1986-12-30
EP0173520A3 (en) 1986-05-14
EP0173520B1 (de) 1990-01-03
KR870001144B1 (ko) 1987-06-11
DK160098B (da) 1991-01-28
PT81004B (pt) 1987-12-30
ATE49211T1 (de) 1990-01-15
FI861704A0 (fi) 1986-04-23
HU203350B (en) 1991-07-29
ES8706116A1 (es) 1987-06-01
KR870002143A (ko) 1987-03-30
WO1986001510A1 (en) 1986-03-13
DE3575140D1 (de) 1990-02-08
FI79319C (fi) 1989-12-11
JPS6157554A (ja) 1986-03-24
ES552044A0 (es) 1987-06-01
IL76175A0 (en) 1985-12-31
HU902020D0 (en) 1990-07-28
PH23065A (en) 1989-03-27
JPH0450316B2 (de) 1992-08-13
DK160098C (da) 1991-06-24
FI79319B (fi) 1989-08-31
EG17287A (en) 1993-02-28
AU4663785A (en) 1986-02-27
ES546377A0 (es) 1987-04-01
DK382685A (da) 1986-02-25
AU553859B2 (en) 1986-07-31

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