ZA855552B - Amidine compounds - Google Patents

Amidine compounds

Info

Publication number
ZA855552B
ZA855552B ZA855552A ZA855552A ZA855552B ZA 855552 B ZA855552 B ZA 855552B ZA 855552 A ZA855552 A ZA 855552A ZA 855552 A ZA855552 A ZA 855552A ZA 855552 B ZA855552 B ZA 855552B
Authority
ZA
South Africa
Prior art keywords
amidine compounds
amidine
compounds
Prior art date
Application number
ZA855552A
Other languages
English (en)
Inventor
Setsuro Fujii
Toshiyuki Okutome
Toyoo Nakayama
Shigeki Nunomura
Kimio Sudo
Shinichi Watanabe
Masateru Kurumi
Takuo Aoyama
Original Assignee
Torii & Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Torii & Co Ltd filed Critical Torii & Co Ltd
Publication of ZA855552B publication Critical patent/ZA855552B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C277/00—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C277/08—Preparation of guanidine or its derivatives, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups of substituted guanidines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/18—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/88—Nitrogen atoms, e.g. allantoin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA855552A 1984-07-25 1985-07-23 Amidine compounds ZA855552B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15504584A JPS6133173A (ja) 1984-07-25 1984-07-25 アミジン化合物

Publications (1)

Publication Number Publication Date
ZA855552B true ZA855552B (en) 1986-03-26

Family

ID=15597463

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA855552A ZA855552B (en) 1984-07-25 1985-07-23 Amidine compounds

Country Status (19)

Country Link
US (2) US4777182A (cs)
EP (1) EP0190356B1 (cs)
JP (1) JPS6133173A (cs)
KR (2) KR870001087B1 (cs)
AU (1) AU567039B2 (cs)
CA (1) CA1254205A (cs)
CS (1) CS255891B2 (cs)
DD (1) DD235637A5 (cs)
DE (1) DE3582057D1 (cs)
DK (1) DK169069B1 (cs)
ES (1) ES8607218A1 (cs)
FI (1) FI78461C (cs)
HU (1) HU195769B (cs)
MX (1) MX160912A (cs)
NO (1) NO163954C (cs)
PH (1) PH20585A (cs)
SU (1) SU1456008A3 (cs)
WO (1) WO1986000893A1 (cs)
ZA (1) ZA855552B (cs)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3824236C1 (cs) * 1988-07-16 1989-12-28 Heidelberger Druckmaschinen Ag, 6900 Heidelberg, De
CA2032420A1 (en) * 1989-12-22 1991-06-23 Akira Okuyama Guanidinobenzene derivatives
US5238964A (en) * 1990-04-05 1993-08-24 Torii & Co., Ltd. Agent for treatment of cerebrovascular contraction
US5652237A (en) * 1994-09-09 1997-07-29 Warner-Lambert Company 2-substituted-4H-3, 1-benzoxazin-4-ones and benzthiazin-4-ones as inhibitors of complement C1r protease for the treatment of inflammatory processes
AU707215B2 (en) * 1995-01-05 1999-07-08 Torii Pharmaceutical Co., Ltd. Thrombolytic agents
ATE222583T1 (de) * 1995-01-05 2002-09-15 Torii Pharmaceutical Co Ltd Derivate substituierter amidinonaphthylester
EP1063973B1 (en) 1998-03-19 2016-11-16 Bristol-Myers Squibb Company Biphasic controlled release delivery system for high solubility pharmaceuticals and method
WO2001077082A1 (en) * 1999-06-02 2001-10-18 Torii Pharmaceutical Co., Ltd. Naphthalene derivatives
WO2001094299A1 (en) * 2000-06-08 2001-12-13 Shizuoka Coffein Co., Ltd. Benzene derivatives
EP1884237B1 (en) 2005-05-17 2010-12-08 Santen Pharmaceutical Co., Ltd. Amidino derivatives for use in the prevention or treatment of glaucoma
EP2119439A3 (en) * 2005-05-17 2010-01-27 Santen Pharmaceutical Co., Ltd. Angiogenesis inhibitor for treating macular degeneration
WO2008058167A2 (en) * 2006-11-07 2008-05-15 Case Western Reserve University Method for treating disorders associated with complement activation
CN107080846A (zh) 2010-07-09 2017-08-22 詹姆斯.特林卡.格林 用于包括瑞格列净的短半衰期药物的组合立即/延迟释放递送系统
JP6252991B2 (ja) * 2012-07-04 2017-12-27 味の素株式会社 ナファモスタットメシル酸塩の製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4292429A (en) * 1978-03-08 1981-09-29 Ciba-Geigy Corporation Imidazole urea and amido compounds
AU527371B2 (en) * 1980-09-16 1983-03-03 Torii & Co., Ltd. Amidine
JPS57179146A (en) * 1981-04-28 1982-11-04 Torii Yakuhin Kk Amidine compound
JPS60130561A (ja) * 1983-12-16 1985-07-12 Torii Yakuhin Kk アミジン誘導体およびそれを含む強心剤

Also Published As

Publication number Publication date
KR860700250A (ko) 1986-08-01
AU567039B2 (en) 1987-11-05
WO1986000893A1 (fr) 1986-02-13
DD235637A5 (de) 1986-05-14
EP0190356A4 (en) 1987-12-09
ES545482A0 (es) 1986-05-16
JPS6133173A (ja) 1986-02-17
DK169069B1 (da) 1994-08-08
CS546385A2 (en) 1987-07-16
US4777182A (en) 1988-10-11
KR870001087B1 (ko) 1987-06-04
AU4549285A (en) 1986-02-25
FI78461B (fi) 1989-04-28
HUT42433A (en) 1987-07-28
FI78461C (fi) 1989-08-10
EP0190356B1 (en) 1991-03-06
DE3582057D1 (en) 1991-04-11
SU1456008A3 (ru) 1989-01-30
HU195769B (en) 1988-07-28
NO860865L (no) 1986-04-10
CS255891B2 (en) 1988-03-15
US4820730A (en) 1989-04-11
FI860904A7 (fi) 1986-03-04
MX160912A (es) 1990-06-14
NO163954C (no) 1990-08-15
JPH0461868B2 (cs) 1992-10-02
ES8607218A1 (es) 1986-05-16
CA1254205A (en) 1989-05-16
PH20585A (en) 1987-02-20
FI860904A0 (fi) 1986-03-04
DK96286D0 (da) 1986-03-03
NO163954B (no) 1990-05-07
EP0190356A1 (en) 1986-08-13
DK96286A (da) 1986-03-03

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