ZA854684B - Long-chain alpha-omega-dicarboxylic acids and derivatives thereof and pharmaceutical compositions containing them - Google Patents

Long-chain alpha-omega-dicarboxylic acids and derivatives thereof and pharmaceutical compositions containing them

Info

Publication number
ZA854684B
ZA854684B ZA854684A ZA854684A ZA854684B ZA 854684 B ZA854684 B ZA 854684B ZA 854684 A ZA854684 A ZA 854684A ZA 854684 A ZA854684 A ZA 854684A ZA 854684 B ZA854684 B ZA 854684B
Authority
ZA
South Africa
Prior art keywords
omega
derivatives
long
pharmaceutical compositions
compositions containing
Prior art date
Application number
ZA854684A
Other languages
English (en)
Inventor
Jacob Bar-Tana
Ernst-Christian Witte
Bernd Hagenbruch
Johannes Pill
Karlheinz Stegmeier
Original Assignee
Epis Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Epis Sa filed Critical Epis Sa
Publication of ZA854684B publication Critical patent/ZA854684B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/42—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings having unsaturation outside the rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
    • C07C55/26—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms containing rings other than aromatic rings
    • C07C55/28—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms containing rings other than aromatic rings monocyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
    • C07C55/32—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/13—Dicarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/34—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings containing more than one carboxyl group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/38—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/305—Saturated compounds containing more than one carboxyl group containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/84—Unsaturated compounds containing keto groups containing six membered aromatic rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA854684A 1984-06-22 1985-06-21 Long-chain alpha-omega-dicarboxylic acids and derivatives thereof and pharmaceutical compositions containing them ZA854684B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843423166 DE3423166A1 (de) 1984-06-22 1984-06-22 Alpha-, omega-dicarbonsaeuren, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten

Publications (1)

Publication Number Publication Date
ZA854684B true ZA854684B (en) 1986-02-26

Family

ID=6238954

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA854684A ZA854684B (en) 1984-06-22 1985-06-21 Long-chain alpha-omega-dicarboxylic acids and derivatives thereof and pharmaceutical compositions containing them

Country Status (17)

Country Link
US (1) US4711896A (tr)
EP (1) EP0185080B1 (tr)
JP (1) JPH0780807B2 (tr)
AU (1) AU4607185A (tr)
CA (1) CA1262552A (tr)
DD (1) DD240541A5 (tr)
DE (2) DE3423166A1 (tr)
DK (1) DK75986D0 (tr)
ES (1) ES8604090A1 (tr)
FI (1) FI860711A0 (tr)
GR (1) GR851509B (tr)
HU (1) HUT38892A (tr)
IL (1) IL75549A (tr)
NO (1) NO860661L (tr)
PT (1) PT80681B (tr)
WO (1) WO1986000298A1 (tr)
ZA (1) ZA854684B (tr)

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US20050020694A1 (en) * 2001-10-11 2005-01-27 Dasseux Jean-Louis Henri Sulfide and disulfide compounds and compositions for cholesterol management and related uses
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RU2520098C2 (ru) 2008-06-26 2014-06-20 Ресверлоджикс Корп. Способы получения производных хиназолинона
JP5635535B2 (ja) 2009-01-08 2014-12-03 レスバーロジックス コーポレイション 心血管疾患の予防および治療のための化合物
CA2992231C (en) 2009-03-18 2022-03-29 Resverlogix Corp. Phenyl-quinazolin-4(3h)-one and phenyl-pyrido[2,3-d]pyrimidin-4(3h)-one derivatives and compositions thereof useful as anti-inflammatory agents
KR20190091564A (ko) 2009-04-22 2019-08-06 리스버로직스 코퍼레이션 신규한 소염제
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BR112013008675A2 (pt) 2010-09-20 2016-06-21 Kareus Therapeutics Sa métodos e composições para o tratamento de diabetes e dislipidemia
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CN107118098B (zh) * 2016-02-25 2020-07-14 中国科学院上海药物研究所 一类脂肪酸类化合物、其制备方法及其用途
US10512624B2 (en) 2016-11-30 2019-12-24 Syndromex Ltd. Long-chain amphipathic dicarboxylic acids for treatment of diabetes type-1
KR20220024816A (ko) 2019-06-21 2022-03-03 에스페리온 테라피유틱스 인코포레이티드 벰페도산 및 그의 조성물을 제조하는 방법
TW202118750A (zh) 2019-07-26 2021-05-16 美商艾斯佩維他治療學公司 官能化的長鏈烴一元及二元羧酸及其用於預防或治療疾病的用途
TW202245804A (zh) 2021-01-25 2022-12-01 美商艾斯佩維他治療學公司 官能化長鏈烴單羧酸及二羧酸及其衍生物以及其於預防或治療疾病之用途
JP2024504720A (ja) 2021-01-25 2024-02-01 エスパーヴィタ セラピューティクス，インコーポレイテッド 官能化長鎖炭化水素モノカルボン酸及びジカルボン酸ならびにそれらの誘導体、ならびに疾患の予防または治療のためのそれらの使用
CN115887435A (zh) * 2021-09-23 2023-04-04 博骥源（上海）生物医药有限公司 长链类化合物及其用途
CN115894220A (zh) * 2021-09-23 2023-04-04 中国科学院上海药物研究所 一类作用于acly的长链类化合物、其制备方法及其用途

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Also Published As

Publication number Publication date
JPS61502537A (ja) 1986-11-06
AU4607185A (en) 1986-01-24
FI860711A (fi) 1986-02-17
DK75986A (da) 1986-02-18
IL75549A (en) 1989-03-31
ES544439A0 (es) 1986-02-01
DE3574130D1 (en) 1989-12-14
EP0185080A1 (tr) 1986-06-25
US4711896A (en) 1987-12-08
DD240541A5 (de) 1986-11-05
IL75549A0 (en) 1985-10-31
EP0185080B1 (de) 1989-11-08
CA1262552A (en) 1989-10-31
PT80681B (de) 1987-05-08
FI860711A0 (fi) 1986-02-17
NO860661L (no) 1986-02-21
GR851509B (tr) 1985-06-25
DK75986D0 (da) 1986-02-18
PT80681A (de) 1985-07-01
ES8604090A1 (es) 1986-02-01
DE3423166A1 (de) 1986-01-02
HUT38892A (en) 1986-07-28
JPH0780807B2 (ja) 1995-08-30
WO1986000298A1 (en) 1986-01-16

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