ZA851062B - Salts of oxazaphosphorine derivatives and process for their production - Google Patents
Salts of oxazaphosphorine derivatives and process for their productionInfo
- Publication number
- ZA851062B ZA851062B ZA851062A ZA851062A ZA851062B ZA 851062 B ZA851062 B ZA 851062B ZA 851062 A ZA851062 A ZA 851062A ZA 851062 A ZA851062 A ZA 851062A ZA 851062 B ZA851062 B ZA 851062B
- Authority
- ZA
- South Africa
- Prior art keywords
- salts
- production
- oxazaphosphorine
- derivatives
- oxazaphosphorine derivatives
- Prior art date
Links
- ZZVDXRCAGGQFAK-UHFFFAOYSA-N 2h-oxazaphosphinine Chemical class N1OC=CC=P1 ZZVDXRCAGGQFAK-UHFFFAOYSA-N 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
- C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
- C07F9/65842—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
- C07F9/65846—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring the phosphorus atom being part of a six-membered ring which may be condensed with another ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3407585 | 1984-03-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA851062B true ZA851062B (en) | 1985-11-27 |
Family
ID=6229317
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA851062A ZA851062B (en) | 1984-03-01 | 1985-02-12 | Salts of oxazaphosphorine derivatives and process for their production |
Country Status (9)
Country | Link |
---|---|
US (1) | US4716242A (da) |
JP (1) | JPH072757B2 (da) |
DD (1) | DD234017A5 (da) |
DK (1) | DK93985A (da) |
ES (1) | ES540778A0 (da) |
PL (2) | PL143712B1 (da) |
PT (1) | PT80024B (da) |
YU (2) | YU31285A (da) |
ZA (1) | ZA851062B (da) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2040394T3 (es) * | 1988-03-19 | 1993-10-16 | Asta Medica Aktiengesellschaft | Procedimiento para preparar un material liofilizado de ifosfamida y mesna. |
DE3835772A1 (de) * | 1988-10-20 | 1990-04-26 | Deutsches Krebsforsch | Tumorhemmende saccharid-konjugate |
US5227373A (en) * | 1991-10-23 | 1993-07-13 | Bristol-Myers Squibb Co. | Lyophilized ifosfamide compositions |
US6828415B2 (en) | 1993-02-19 | 2004-12-07 | Zentaris Gmbh | Oligopeptide lyophilisate, their preparation and use |
US5873584A (en) * | 1995-01-17 | 1999-02-23 | Rike Inline, Inc. | In-line roller skate frame |
DE102004031569A1 (de) * | 2004-06-29 | 2006-02-02 | Baxter International Inc., Deerfield | Verfahren zur Herstellung von lagerstabiler Mafosfamid-Lysin-Salz Lyophilisat Bulkware und zu dessen Weiterverarbeitung zu Mafosfamid-Lysin-Salz Lyophilisat in dosierter Form |
DK2336140T3 (da) * | 2004-10-25 | 2016-03-21 | Dekk Tec Inc | Salte af isophosphoramidsennep og analoger deraf som antitumor-midler |
WO2010099213A1 (en) * | 2009-02-24 | 2010-09-02 | Dekk-Tec, Inc. | Complexes of 4-hydroperoxy ifosfamide as anti-tumor agents |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5159886A (da) * | 1974-11-20 | 1976-05-25 | Shionogi Seiyaku Kk | |
EP0002495B1 (de) * | 1977-12-14 | 1984-02-15 | Asta-Werke Aktiengesellschaft Chemische Fabrik | Erzeugnisse zur Anwendung in der cytostatischen Therapie |
JPS54157580A (en) * | 1978-05-29 | 1979-12-12 | Otsuka Pharmaceut Co Ltd | Optically active oxazaphosphorine derivative |
JPS5651184A (en) * | 1979-10-03 | 1981-05-08 | Hitachi Ltd | Color solid image pickup device |
DE3133309A1 (de) * | 1980-09-10 | 1982-04-15 | Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld | 4-carbamoyloxy-oxazaphosphorine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen |
DE3220672A1 (de) * | 1981-03-24 | 1983-12-08 | Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld | Cis-oxazaphosphorin-4-thio-alkansulfonsaeuren, ihre neutralen salze, verfahren zur herstellung derselben und diese enthaltenden pharmazeutischen praeparate |
DE3111428A1 (de) * | 1981-03-24 | 1982-10-07 | Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld | Oxazaphosphorin-4-thio-alkansulfonsaeuren und deren neutrale salze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen |
DE3220432A1 (de) * | 1981-03-24 | 1983-12-01 | Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld | Oxazaphosphorin-4-thio-alkansulfonsaeure, ihre neutralen salze, verfahren zur herstellung derselben und diese enthaltenden pharmazeutischen praeparate |
DE3132221A1 (de) * | 1981-08-14 | 1983-05-19 | Behringwerke Ag, 3550 Marburg | Neue cyclophosphamid-derivate, verfahren zu ihrer herstellung und ihre verwendung |
DE3133077A1 (de) * | 1981-08-21 | 1983-03-10 | Henkel KGaA, 4000 Düsseldorf | Neue cytostatisch wirksame epoxidgruppen tragende 1,3,2-oxazaphosphorin-verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung in pharmazeutischen zubereitungen |
US4618692A (en) * | 1981-09-03 | 1986-10-21 | Asta-Werke Aktiengesellschaft | 4-carbamoyloxy-oxazaphosphorins |
DE3279834D1 (en) * | 1981-12-31 | 1989-08-31 | Asta Pharma Ag | 4-sulfido-oxaza phosphorines and their use in the treatment of cancer, and in immunosuppression |
DE3247436A1 (de) * | 1981-12-31 | 1983-07-14 | Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld | 4-sulfido-oxazaphosphorine und deren verwendung bei der krebsbekaempfung und zur immunsuppression |
DE3505482A1 (de) * | 1984-03-01 | 1985-09-05 | Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld | Neue salze von oxazaphosphorin-derivaten |
-
1985
- 1985-02-12 ZA ZA851062A patent/ZA851062B/xx unknown
- 1985-02-22 US US06/704,465 patent/US4716242A/en not_active Expired - Lifetime
- 1985-02-28 PL PL1985252161A patent/PL143712B1/pl unknown
- 1985-02-28 PL PL1985266394A patent/PL146149B1/pl unknown
- 1985-02-28 DD DD85273643A patent/DD234017A5/de unknown
- 1985-02-28 PT PT80024A patent/PT80024B/pt unknown
- 1985-02-28 YU YU00312/85A patent/YU31285A/xx unknown
- 1985-02-28 DK DK93985A patent/DK93985A/da not_active Application Discontinuation
- 1985-02-28 ES ES540778A patent/ES540778A0/es active Granted
- 1985-03-01 JP JP60038978A patent/JPH072757B2/ja not_active Expired - Fee Related
-
1987
- 1987-06-26 YU YU01202/87A patent/YU120287A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
JPS60222494A (ja) | 1985-11-07 |
DK93985D0 (da) | 1985-02-28 |
YU120287A (en) | 1988-04-30 |
ES8602831A1 (es) | 1985-12-01 |
PT80024A (de) | 1985-03-01 |
DK93985A (da) | 1985-09-02 |
PL252161A1 (en) | 1986-08-26 |
PL143712B1 (en) | 1988-03-31 |
JPH072757B2 (ja) | 1995-01-18 |
PL146149B1 (en) | 1988-12-31 |
YU31285A (en) | 1988-02-29 |
DD234017A5 (de) | 1986-03-19 |
ES540778A0 (es) | 1985-12-01 |
US4716242A (en) | 1987-12-29 |
PT80024B (pt) | 1987-09-18 |
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