YU120287A - Process for producing new salts of oxaza-phosphorine derivatives - Google Patents

Process for producing new salts of oxaza-phosphorine derivatives

Info

Publication number
YU120287A
YU120287A YU01202/87A YU120287A YU120287A YU 120287 A YU120287 A YU 120287A YU 01202/87 A YU01202/87 A YU 01202/87A YU 120287 A YU120287 A YU 120287A YU 120287 A YU120287 A YU 120287A
Authority
YU
Yugoslavia
Prior art keywords
phosphorine
oxaza
derivatives
producing new
new salts
Prior art date
Application number
YU01202/87A
Other languages
English (en)
Inventor
J Engel
U Niemeyer
J Pohl
A Kleemann
P Hilgard
Original Assignee
Asta Werke Ag Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Werke Ag Chem Fab filed Critical Asta Werke Ag Chem Fab
Publication of YU120287A publication Critical patent/YU120287A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
    • C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
    • C07F9/65842—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
    • C07F9/65846—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring the phosphorus atom being part of a six-membered ring which may be condensed with another ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
YU01202/87A 1984-03-01 1987-06-26 Process for producing new salts of oxaza-phosphorine derivatives YU120287A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3407585 1984-03-01

Publications (1)

Publication Number Publication Date
YU120287A true YU120287A (en) 1988-04-30

Family

ID=6229317

Family Applications (2)

Application Number Title Priority Date Filing Date
YU00312/85A YU31285A (en) 1984-03-01 1985-02-28 Process for producing salts of oxazaphosphorine derivatives
YU01202/87A YU120287A (en) 1984-03-01 1987-06-26 Process for producing new salts of oxaza-phosphorine derivatives

Family Applications Before (1)

Application Number Title Priority Date Filing Date
YU00312/85A YU31285A (en) 1984-03-01 1985-02-28 Process for producing salts of oxazaphosphorine derivatives

Country Status (9)

Country Link
US (1) US4716242A (xx)
JP (1) JPH072757B2 (xx)
DD (1) DD234017A5 (xx)
DK (1) DK93985A (xx)
ES (1) ES540778A0 (xx)
PL (2) PL143712B1 (xx)
PT (1) PT80024B (xx)
YU (2) YU31285A (xx)
ZA (1) ZA851062B (xx)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2040394T3 (es) * 1988-03-19 1993-10-16 Asta Medica Aktiengesellschaft Procedimiento para preparar un material liofilizado de ifosfamida y mesna.
DE3835772A1 (de) * 1988-10-20 1990-04-26 Deutsches Krebsforsch Tumorhemmende saccharid-konjugate
US5227373A (en) * 1991-10-23 1993-07-13 Bristol-Myers Squibb Co. Lyophilized ifosfamide compositions
US6828415B2 (en) 1993-02-19 2004-12-07 Zentaris Gmbh Oligopeptide lyophilisate, their preparation and use
US5873584A (en) * 1995-01-17 1999-02-23 Rike Inline, Inc. In-line roller skate frame
DE102004031569A1 (de) * 2004-06-29 2006-02-02 Baxter International Inc., Deerfield Verfahren zur Herstellung von lagerstabiler Mafosfamid-Lysin-Salz Lyophilisat Bulkware und zu dessen Weiterverarbeitung zu Mafosfamid-Lysin-Salz Lyophilisat in dosierter Form
DK2336140T3 (en) * 2004-10-25 2016-03-21 Dekk Tec Inc Of isophosphoramide mustard salts and analogs thereof as antitumor agents
WO2010099213A1 (en) * 2009-02-24 2010-09-02 Dekk-Tec, Inc. Complexes of 4-hydroperoxy ifosfamide as anti-tumor agents

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5159886A (xx) * 1974-11-20 1976-05-25 Shionogi Seiyaku Kk
EP0002495B1 (de) * 1977-12-14 1984-02-15 Asta-Werke Aktiengesellschaft Chemische Fabrik Erzeugnisse zur Anwendung in der cytostatischen Therapie
JPS54157580A (en) * 1978-05-29 1979-12-12 Otsuka Pharmaceut Co Ltd Optically active oxazaphosphorine derivative
JPS5651184A (en) * 1979-10-03 1981-05-08 Hitachi Ltd Color solid image pickup device
DE3133309A1 (de) * 1980-09-10 1982-04-15 Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld 4-carbamoyloxy-oxazaphosphorine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
DE3220672A1 (de) * 1981-03-24 1983-12-08 Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld Cis-oxazaphosphorin-4-thio-alkansulfonsaeuren, ihre neutralen salze, verfahren zur herstellung derselben und diese enthaltenden pharmazeutischen praeparate
DE3111428A1 (de) * 1981-03-24 1982-10-07 Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld Oxazaphosphorin-4-thio-alkansulfonsaeuren und deren neutrale salze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
DE3220432A1 (de) * 1981-03-24 1983-12-01 Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld Oxazaphosphorin-4-thio-alkansulfonsaeure, ihre neutralen salze, verfahren zur herstellung derselben und diese enthaltenden pharmazeutischen praeparate
DE3132221A1 (de) * 1981-08-14 1983-05-19 Behringwerke Ag, 3550 Marburg Neue cyclophosphamid-derivate, verfahren zu ihrer herstellung und ihre verwendung
DE3133077A1 (de) * 1981-08-21 1983-03-10 Henkel KGaA, 4000 Düsseldorf Neue cytostatisch wirksame epoxidgruppen tragende 1,3,2-oxazaphosphorin-verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung in pharmazeutischen zubereitungen
US4618692A (en) * 1981-09-03 1986-10-21 Asta-Werke Aktiengesellschaft 4-carbamoyloxy-oxazaphosphorins
DE3279834D1 (en) * 1981-12-31 1989-08-31 Asta Pharma Ag 4-sulfido-oxaza phosphorines and their use in the treatment of cancer, and in immunosuppression
DE3247436A1 (de) * 1981-12-31 1983-07-14 Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld 4-sulfido-oxazaphosphorine und deren verwendung bei der krebsbekaempfung und zur immunsuppression
DE3505482A1 (de) * 1984-03-01 1985-09-05 Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld Neue salze von oxazaphosphorin-derivaten

Also Published As

Publication number Publication date
JPS60222494A (ja) 1985-11-07
DK93985D0 (da) 1985-02-28
ES8602831A1 (es) 1985-12-01
PT80024A (de) 1985-03-01
DK93985A (da) 1985-09-02
PL252161A1 (en) 1986-08-26
PL143712B1 (en) 1988-03-31
JPH072757B2 (ja) 1995-01-18
PL146149B1 (en) 1988-12-31
YU31285A (en) 1988-02-29
DD234017A5 (de) 1986-03-19
ES540778A0 (es) 1985-12-01
ZA851062B (en) 1985-11-27
US4716242A (en) 1987-12-29
PT80024B (pt) 1987-09-18

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