ZA848388B - Triazine compounds having cardiovascular activity - Google Patents
Triazine compounds having cardiovascular activityInfo
- Publication number
- ZA848388B ZA848388B ZA848388A ZA848388A ZA848388B ZA 848388 B ZA848388 B ZA 848388B ZA 848388 A ZA848388 A ZA 848388A ZA 848388 A ZA848388 A ZA 848388A ZA 848388 B ZA848388 B ZA 848388B
- Authority
- ZA
- South Africa
- Prior art keywords
- triazine compounds
- cardiovascular activity
- cardiovascular
- activity
- triazine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D253/075—Two hetero atoms, in positions 3 and 5
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB838328757A GB8328757D0 (en) | 1983-10-27 | 1983-10-27 | Chemical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA848388B true ZA848388B (en) | 1986-06-25 |
Family
ID=10550834
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA848388A ZA848388B (en) | 1983-10-27 | 1984-10-26 | Triazine compounds having cardiovascular activity |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4649139A (el) |
| EP (1) | EP0142306A3 (el) |
| JP (1) | JPS60109577A (el) |
| KR (1) | KR890000991B1 (el) |
| AU (1) | AU564667B2 (el) |
| CA (1) | CA1261328A (el) |
| DD (1) | DD224033A5 (el) |
| DK (1) | DK512184A (el) |
| ES (1) | ES8606304A1 (el) |
| FI (1) | FI844212L (el) |
| GB (1) | GB8328757D0 (el) |
| GR (1) | GR80723B (el) |
| HU (1) | HU191566B (el) |
| IL (1) | IL73332A (el) |
| MC (1) | MC1628A1 (el) |
| NZ (1) | NZ210000A (el) |
| PH (1) | PH21926A (el) |
| PL (1) | PL144899B1 (el) |
| PT (1) | PT79416B (el) |
| SU (1) | SU1371500A3 (el) |
| ZA (1) | ZA848388B (el) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8613183D0 (en) * | 1986-05-30 | 1986-07-02 | Wellcome Found | Triazine salt |
| GB9012312D0 (en) * | 1990-06-01 | 1990-07-18 | Wellcome Found | Pharmacologically active cns compounds |
| GB9218113D0 (en) * | 1992-08-26 | 1992-10-14 | Lilly Industries Ltd | Pharmaceutical compounds |
| GB9726987D0 (en) | 1997-12-22 | 1998-02-18 | Glaxo Group Ltd | Compounds |
| US6639072B1 (en) | 2000-01-03 | 2003-10-28 | Rpg Life Sciences Limited | Process for the preparation of 6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine, commonly known as lamotrigine |
| IL134730A (en) * | 2000-02-25 | 2003-10-31 | Chemagis Ltd | Process for preparing substituted benzoyl cyanide amidinohydrazones |
| EP1554572B1 (en) | 2001-07-25 | 2009-10-14 | Raptor Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
| EP3827747A1 (en) | 2005-04-28 | 2021-06-02 | Otsuka Pharmaceutical Co., Ltd. | Pharma-informatics system |
| GB0613836D0 (en) | 2006-07-13 | 2006-08-23 | Univ Greenwich | New medical use of triazine derivatives |
| EP2063905B1 (en) | 2006-09-18 | 2014-07-30 | Raptor Pharmaceutical Inc | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
| GB0800741D0 (en) | 2008-01-16 | 2008-02-20 | Univ Greenwich | Cyclic triazo and diazo sodium channel blockers |
| NZ616673A (en) | 2009-02-20 | 2014-08-29 | To Bbb Holding B V | Glutathione-based drug delivery system |
| ES2942923T3 (es) | 2009-05-06 | 2023-06-07 | Laboratory Skin Care Inc | Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas |
| GB2471713A (en) | 2009-07-08 | 2011-01-12 | Univ Greenwich | 1,2,4-triazine derivatives and their use as sodium channel blockers |
| GB2471729A (en) * | 2009-07-08 | 2011-01-12 | Univ Greenwich | 1,2,4-triazine derivatives and their use as sodium channel blockers |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
| JP2018524302A (ja) | 2015-06-12 | 2018-08-30 | ユニバーシティ オブ グリニッジ | インターフェロン‐γ阻害剤としてのトリアジン誘導体 |
| CN109810070B (zh) * | 2019-01-29 | 2022-03-15 | 太原理工大学 | 一种含有双酰氧基结构的三嗪酮衍生物及其制备方法和应用 |
| GB202006080D0 (en) | 2020-04-24 | 2020-06-10 | Univ Greenwich | Cytokine storm syndrome |
| GB202006076D0 (en) | 2020-04-24 | 2020-06-10 | Univ Greenwich | Interleukin inhibitors |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB759014A (en) * | 1952-02-26 | 1956-10-10 | Wellcome Found | Improvements in triazines and their manufacture |
| BG15760A3 (bg) * | 1968-06-29 | 1976-06-21 | Неизвестен | Метод за получаване на производни на 5-имино- 1, 2, 4- триазина |
| US3637688A (en) * | 1970-01-09 | 1972-01-25 | American Home Prod | 6-(fluoro and trifluoromethyl phenyl)-3 5-diamino - 1 2 4 - triazines and substituted - 6 - phenylalkyl-3,5-diamino-1 2 4-triazines |
| DE2003144C3 (de) * | 1970-01-24 | 1980-01-10 | Bayer Ag, 5090 Leverkusen | 5-Imino-6-alkyl-1^2,4-triazin-Derivate und Verfahren zu deren Herstellung |
| GR68380B (el) * | 1979-06-01 | 1981-12-28 | Wellcome Found | |
| EP0021120B1 (en) * | 1979-06-01 | 1983-04-06 | The Wellcome Foundation Limited | 3,5-diamino-1,2,4-triazine derivatives, process for preparing such compounds and pharmaceutical compositions containing them |
| US4616014A (en) * | 1981-10-22 | 1986-10-07 | Fujisawa Pharmaceutical Co., Ltd. | Triazine derivatives, and pharmaceutical compositions comprising the same |
-
1983
- 1983-10-27 GB GB838328757A patent/GB8328757D0/en active Pending
-
1984
- 1984-10-19 GR GR80723A patent/GR80723B/el unknown
- 1984-10-22 US US06/663,682 patent/US4649139A/en not_active Expired - Fee Related
- 1984-10-26 AU AU34758/84A patent/AU564667B2/en not_active Ceased
- 1984-10-26 PH PH31367A patent/PH21926A/en unknown
- 1984-10-26 CA CA000466473A patent/CA1261328A/en not_active Expired
- 1984-10-26 FI FI844212A patent/FI844212L/fi not_active Application Discontinuation
- 1984-10-26 SU SU843805251A patent/SU1371500A3/ru active
- 1984-10-26 DK DK512184A patent/DK512184A/da not_active Application Discontinuation
- 1984-10-26 MC MC841734A patent/MC1628A1/xx unknown
- 1984-10-26 PT PT79416A patent/PT79416B/pt unknown
- 1984-10-26 ES ES537104A patent/ES8606304A1/es not_active Expired
- 1984-10-26 DD DD84268757A patent/DD224033A5/de unknown
- 1984-10-26 NZ NZ210000A patent/NZ210000A/en unknown
- 1984-10-26 IL IL73332A patent/IL73332A/xx unknown
- 1984-10-26 HU HU844003A patent/HU191566B/hu not_active IP Right Cessation
- 1984-10-26 EP EP84307374A patent/EP0142306A3/en not_active Ceased
- 1984-10-26 ZA ZA848388A patent/ZA848388B/xx unknown
- 1984-10-26 KR KR1019840006660A patent/KR890000991B1/ko active IP Right Grant
- 1984-10-26 PL PL1984250213A patent/PL144899B1/pl unknown
- 1984-10-26 JP JP59225636A patent/JPS60109577A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| PT79416B (en) | 1986-11-13 |
| DK512184A (da) | 1985-04-28 |
| EP0142306A2 (en) | 1985-05-22 |
| AU564667B2 (en) | 1987-08-20 |
| ES537104A0 (es) | 1986-04-16 |
| AU3475884A (en) | 1985-05-09 |
| DK512184D0 (da) | 1984-10-26 |
| JPS60109577A (ja) | 1985-06-15 |
| MC1628A1 (fr) | 1985-09-26 |
| HU191566B (en) | 1987-03-30 |
| IL73332A (en) | 1988-06-30 |
| DD224033A5 (de) | 1985-06-26 |
| NZ210000A (en) | 1987-08-31 |
| HUT36102A (en) | 1985-08-28 |
| SU1371500A3 (ru) | 1988-01-30 |
| FI844212L (fi) | 1985-04-28 |
| US4649139A (en) | 1987-03-10 |
| EP0142306A3 (en) | 1986-11-20 |
| KR850002964A (ko) | 1985-05-28 |
| GR80723B (en) | 1985-02-07 |
| PL144899B1 (en) | 1988-07-30 |
| GB8328757D0 (en) | 1983-11-30 |
| KR890000991B1 (ko) | 1989-04-15 |
| ES8606304A1 (es) | 1986-04-16 |
| PL250213A1 (en) | 1985-12-03 |
| FI844212A0 (fi) | 1984-10-26 |
| IL73332A0 (en) | 1985-01-31 |
| PH21926A (en) | 1988-04-08 |
| CA1261328A (en) | 1989-09-26 |
| PT79416A (en) | 1984-11-01 |
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