IL73332A - 5-amino-6-phenyl-2,3-dihydro-3-imino-1,2,4-triazine derivatives,their preparation and pharmaceutical compositions containing them - Google Patents
5-amino-6-phenyl-2,3-dihydro-3-imino-1,2,4-triazine derivatives,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL73332A IL73332A IL73332A IL7333284A IL73332A IL 73332 A IL73332 A IL 73332A IL 73332 A IL73332 A IL 73332A IL 7333284 A IL7333284 A IL 7333284A IL 73332 A IL73332 A IL 73332A
- Authority
- IL
- Israel
- Prior art keywords
- imino
- dihydro
- phenyl
- amino
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D253/00—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00
- C07D253/02—Heterocyclic compounds containing six-membered rings having three nitrogen atoms as the only ring hetero atoms, not provided for by group C07D251/00 not condensed with other rings
- C07D253/06—1,2,4-Triazines
- C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
- C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D253/075—Two hetero atoms, in positions 3 and 5
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB838328757A GB8328757D0 (en) | 1983-10-27 | 1983-10-27 | Chemical compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL73332A0 IL73332A0 (en) | 1985-01-31 |
| IL73332A true IL73332A (en) | 1988-06-30 |
Family
ID=10550834
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL73332A IL73332A (en) | 1983-10-27 | 1984-10-26 | 5-amino-6-phenyl-2,3-dihydro-3-imino-1,2,4-triazine derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4649139A (xx) |
| EP (1) | EP0142306A3 (xx) |
| JP (1) | JPS60109577A (xx) |
| KR (1) | KR890000991B1 (xx) |
| AU (1) | AU564667B2 (xx) |
| CA (1) | CA1261328A (xx) |
| DD (1) | DD224033A5 (xx) |
| DK (1) | DK512184A (xx) |
| ES (1) | ES8606304A1 (xx) |
| FI (1) | FI844212L (xx) |
| GB (1) | GB8328757D0 (xx) |
| GR (1) | GR80723B (xx) |
| HU (1) | HU191566B (xx) |
| IL (1) | IL73332A (xx) |
| MC (1) | MC1628A1 (xx) |
| NZ (1) | NZ210000A (xx) |
| PH (1) | PH21926A (xx) |
| PL (1) | PL144899B1 (xx) |
| PT (1) | PT79416B (xx) |
| SU (1) | SU1371500A3 (xx) |
| ZA (1) | ZA848388B (xx) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8613183D0 (en) * | 1986-05-30 | 1986-07-02 | Wellcome Found | Triazine salt |
| GB9012312D0 (en) * | 1990-06-01 | 1990-07-18 | Wellcome Found | Pharmacologically active cns compounds |
| GB9218113D0 (en) * | 1992-08-26 | 1992-10-14 | Lilly Industries Ltd | Pharmaceutical compounds |
| GB9726987D0 (en) | 1997-12-22 | 1998-02-18 | Glaxo Group Ltd | Compounds |
| AU763244B2 (en) * | 2000-01-03 | 2003-07-17 | Rpg Life Sciences Limited | A process for the preparation of 6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine, commonly known as lamotrigine |
| IL134730A (en) * | 2000-02-25 | 2003-10-31 | Chemagis Ltd | Process for preparing substituted benzoyl cyanide amidinohydrazones |
| DE60234057D1 (de) | 2001-07-25 | 2009-11-26 | Raptor Pharmaceutical Inc | Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke |
| SI1889198T1 (sl) | 2005-04-28 | 2015-02-27 | Proteus Digital Health, Inc. | Farma-informacijski sistem |
| GB0613836D0 (en) * | 2006-07-13 | 2006-08-23 | Univ Greenwich | New medical use of triazine derivatives |
| MX2009002893A (es) | 2006-09-18 | 2009-07-10 | Raptor Pharmaceutical Inc | Tratamiento de trastornos hepaticos mediante la administracion de conjugados de la proteina asociada al receptor (rap). |
| GB0800741D0 (en) | 2008-01-16 | 2008-02-20 | Univ Greenwich | Cyclic triazo and diazo sodium channel blockers |
| WO2010095940A2 (en) | 2009-02-20 | 2010-08-26 | To-Bbb Holding B.V. | Glutathione-based drug delivery system |
| NZ596876A (en) | 2009-05-06 | 2014-01-31 | Lab Skin Care Inc | Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same |
| GB2471713A (en) * | 2009-07-08 | 2011-01-12 | Univ Greenwich | 1,2,4-triazine derivatives and their use as sodium channel blockers |
| GB2471729A (en) * | 2009-07-08 | 2011-01-12 | Univ Greenwich | 1,2,4-triazine derivatives and their use as sodium channel blockers |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
| CN107921046B (zh) | 2015-06-12 | 2022-10-14 | 格林威治大学 | 作为干扰素-γ抑制剂的三嗪衍生物 |
| CN109810070B (zh) * | 2019-01-29 | 2022-03-15 | 太原理工大学 | 一种含有双酰氧基结构的三嗪酮衍生物及其制备方法和应用 |
| GB202006080D0 (en) | 2020-04-24 | 2020-06-10 | Univ Greenwich | Cytokine storm syndrome |
| GB202006076D0 (en) | 2020-04-24 | 2020-06-10 | Univ Greenwich | Interleukin inhibitors |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB759014A (en) * | 1952-02-26 | 1956-10-10 | Wellcome Found | Improvements in triazines and their manufacture |
| BG15760A3 (bg) * | 1968-06-29 | 1976-06-21 | Неизвестен | Метод за получаване на производни на 5-имино- 1, 2, 4- триазина |
| US3637688A (en) * | 1970-01-09 | 1972-01-25 | American Home Prod | 6-(fluoro and trifluoromethyl phenyl)-3 5-diamino - 1 2 4 - triazines and substituted - 6 - phenylalkyl-3,5-diamino-1 2 4-triazines |
| DE2003144C3 (de) * | 1970-01-24 | 1980-01-10 | Bayer Ag, 5090 Leverkusen | 5-Imino-6-alkyl-1^2,4-triazin-Derivate und Verfahren zu deren Herstellung |
| DK153787C (da) * | 1979-06-01 | 1989-01-16 | Wellcome Found | Analogifremgangsmaade til fremstilling af substituerede 3,5-diamino-6-phenyl-1,2,4-triaziner og alfa-cyanobenzyliden-aminoguanidinforbindelser til anvendelse som mellemprodukter herved |
| EP0021120B1 (en) * | 1979-06-01 | 1983-04-06 | The Wellcome Foundation Limited | 3,5-diamino-1,2,4-triazine derivatives, process for preparing such compounds and pharmaceutical compositions containing them |
| US4616014A (en) * | 1981-10-22 | 1986-10-07 | Fujisawa Pharmaceutical Co., Ltd. | Triazine derivatives, and pharmaceutical compositions comprising the same |
-
1983
- 1983-10-27 GB GB838328757A patent/GB8328757D0/en active Pending
-
1984
- 1984-10-19 GR GR80723A patent/GR80723B/el unknown
- 1984-10-22 US US06/663,682 patent/US4649139A/en not_active Expired - Fee Related
- 1984-10-26 KR KR1019840006660A patent/KR890000991B1/ko active IP Right Grant
- 1984-10-26 JP JP59225636A patent/JPS60109577A/ja active Pending
- 1984-10-26 ES ES537104A patent/ES8606304A1/es not_active Expired
- 1984-10-26 SU SU843805251A patent/SU1371500A3/ru active
- 1984-10-26 DK DK512184A patent/DK512184A/da not_active Application Discontinuation
- 1984-10-26 FI FI844212A patent/FI844212L/fi not_active Application Discontinuation
- 1984-10-26 IL IL73332A patent/IL73332A/xx unknown
- 1984-10-26 NZ NZ210000A patent/NZ210000A/en unknown
- 1984-10-26 AU AU34758/84A patent/AU564667B2/en not_active Ceased
- 1984-10-26 PH PH31367A patent/PH21926A/en unknown
- 1984-10-26 MC MC841734A patent/MC1628A1/xx unknown
- 1984-10-26 PT PT79416A patent/PT79416B/pt unknown
- 1984-10-26 DD DD84268757A patent/DD224033A5/de unknown
- 1984-10-26 HU HU844003A patent/HU191566B/hu not_active IP Right Cessation
- 1984-10-26 ZA ZA848388A patent/ZA848388B/xx unknown
- 1984-10-26 CA CA000466473A patent/CA1261328A/en not_active Expired
- 1984-10-26 PL PL1984250213A patent/PL144899B1/pl unknown
- 1984-10-26 EP EP84307374A patent/EP0142306A3/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DK512184D0 (da) | 1984-10-26 |
| GB8328757D0 (en) | 1983-11-30 |
| NZ210000A (en) | 1987-08-31 |
| CA1261328A (en) | 1989-09-26 |
| DK512184A (da) | 1985-04-28 |
| AU564667B2 (en) | 1987-08-20 |
| FI844212L (fi) | 1985-04-28 |
| ES8606304A1 (es) | 1986-04-16 |
| PH21926A (en) | 1988-04-08 |
| PT79416A (en) | 1984-11-01 |
| PT79416B (en) | 1986-11-13 |
| AU3475884A (en) | 1985-05-09 |
| HUT36102A (en) | 1985-08-28 |
| FI844212A0 (fi) | 1984-10-26 |
| PL250213A1 (en) | 1985-12-03 |
| PL144899B1 (en) | 1988-07-30 |
| ES537104A0 (es) | 1986-04-16 |
| ZA848388B (en) | 1986-06-25 |
| EP0142306A2 (en) | 1985-05-22 |
| KR890000991B1 (ko) | 1989-04-15 |
| JPS60109577A (ja) | 1985-06-15 |
| MC1628A1 (fr) | 1985-09-26 |
| EP0142306A3 (en) | 1986-11-20 |
| SU1371500A3 (ru) | 1988-01-30 |
| GR80723B (en) | 1985-02-07 |
| HU191566B (en) | 1987-03-30 |
| KR850002964A (ko) | 1985-05-28 |
| IL73332A0 (en) | 1985-01-31 |
| US4649139A (en) | 1987-03-10 |
| DD224033A5 (de) | 1985-06-26 |
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