ZA846104B - Stable antibacterial lyophilizates - Google Patents

Stable antibacterial lyophilizates

Info

Publication number
ZA846104B
ZA846104B ZA846104A ZA846104A ZA846104B ZA 846104 B ZA846104 B ZA 846104B ZA 846104 A ZA846104 A ZA 846104A ZA 846104 A ZA846104 A ZA 846104A ZA 846104 B ZA846104 B ZA 846104B
Authority
ZA
South Africa
Prior art keywords
lyophilizates
stable antibacterial
antibacterial
stable
antibacterial lyophilizates
Prior art date
Application number
ZA846104A
Other languages
English (en)
Inventor
Kazuhiro Shima
Masayoshi Inoue
Takayuki Tsukada
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of ZA846104B publication Critical patent/ZA846104B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA846104A 1983-08-22 1984-08-07 Stable antibacterial lyophilizates ZA846104B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58153938A JPS6045514A (ja) 1983-08-22 1983-08-22 安定な抗菌性凍結乾燥製剤

Publications (1)

Publication Number Publication Date
ZA846104B true ZA846104B (en) 1985-03-27

Family

ID=15573358

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA846104A ZA846104B (en) 1983-08-22 1984-08-07 Stable antibacterial lyophilizates

Country Status (20)

Country Link
US (1) US4616083A (cs)
EP (1) EP0134568B1 (cs)
JP (1) JPS6045514A (cs)
KR (1) KR910004575B1 (cs)
AR (1) AR242390A1 (cs)
AT (1) ATE38774T1 (cs)
CA (1) CA1231896A (cs)
DE (2) DE134568T1 (cs)
DK (1) DK163032C (cs)
ES (1) ES8505815A1 (cs)
FI (1) FI83476C (cs)
GB (1) GB2145333B (cs)
GR (1) GR80147B (cs)
IE (1) IE57587B1 (cs)
IL (1) IL72731A (cs)
NO (1) NO165223C (cs)
NZ (1) NZ209111A (cs)
PT (1) PT79093B (cs)
SU (1) SU1433390A3 (cs)
ZA (1) ZA846104B (cs)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61130223A (ja) * 1984-11-28 1986-06-18 Shionogi & Co Ltd 抗菌性凍結乾燥製剤
US4808617A (en) * 1985-12-18 1989-02-28 Bristol-Myers Company Lyophilized or precipitated cephalosporin zwitterion and salt combination
DE3801179A1 (de) * 1988-01-18 1989-07-27 Hoechst Ag Stabilisierung von cephalosporinderivaten durch trocknung mit einem stabilisator sowie stabile zubereitungsformen mit cephalosporinderivaten
EP0556394B1 (en) * 1990-11-06 2002-06-19 Nippon Shinyaku Company, Limited Lyophilized preparation and production thereof
US7378408B2 (en) * 2001-11-30 2008-05-27 Pfizer Inc. Methods of treatment and formulations of cephalosporin
WO2004000323A1 (ja) * 2002-06-21 2003-12-31 Shionogi & Co., Ltd. セフェム化合物の注射用医薬組成物
KR101314500B1 (ko) * 2012-12-28 2013-10-07 제일약품주식회사 안정성이 개선된 옥사세펨 제제 및 그 제조방법
CN110279698B (zh) 2013-03-15 2022-10-28 默沙东有限责任公司 头孢特咯瓒抗生素组合物
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
US9320740B2 (en) 2013-03-15 2016-04-26 Merck Sharp & Dohme Corp. Ceftolozane-tazobactam pharmaceutical compositions
ES2800603T3 (es) 2013-09-09 2021-01-04 Merck Sharp & Dohme Tratamiento de infecciones con ceftolozano/tazobactam en sujetos con insuficiencia renal
US20150094293A1 (en) 2013-09-27 2015-04-02 Calixa Therapeutics, Inc. Solid forms of ceftolozane
EP3189841B1 (en) * 2014-09-04 2023-11-22 Shionogi & Co., Ltd. Pharmaceutical preparation comprising cephalosporin having catechol groups

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA919593A (en) * 1969-03-31 1973-01-23 Nippon Kayaku Kabushiki Kaisha Process for manufacturing a preparation containing finely divided chloramphenicol palmitate
US3993753A (en) * 1974-08-26 1976-11-23 American Home Products Corporation Anhydrous ampicillin stabilization and resultant compositions
US4180571A (en) * 1976-03-25 1979-12-25 Shionogi & Co., Ltd. Arylmalonamido-1-oxadethiacephalosporins
JPS5711909A (en) * 1980-06-23 1982-01-21 Shionogi & Co Ltd Stable freeze-dried preparation of beta-lactam
JPS5762284A (en) * 1980-10-01 1982-04-15 Sumitomo Chem Co Ltd Stabilizing method
JPS59139385A (ja) * 1982-12-23 1984-08-10 Shionogi & Co Ltd フルオロメチルチオオキサセフアロスポリン

Also Published As

Publication number Publication date
NO165223B (no) 1990-10-08
GB2145333A (en) 1985-03-27
NO843313L (no) 1985-02-25
PT79093A (en) 1984-09-01
CA1231896A (en) 1988-01-26
DE3475268D1 (en) 1988-12-29
IE842072L (en) 1985-02-22
FI843261L (fi) 1985-02-23
ES535654A0 (es) 1985-06-16
DK163032C (da) 1992-06-15
PT79093B (en) 1986-08-14
GB8420296D0 (en) 1984-09-12
JPS6045514A (ja) 1985-03-12
EP0134568A1 (en) 1985-03-20
AR242390A1 (es) 1993-03-31
NO165223C (no) 1991-01-30
IL72731A0 (en) 1984-11-30
EP0134568B1 (en) 1988-11-23
DK163032B (da) 1992-01-13
JPH0370688B2 (cs) 1991-11-08
FI83476C (fi) 1991-07-25
IE57587B1 (en) 1993-01-13
IL72731A (en) 1988-04-29
KR910004575B1 (ko) 1991-07-06
US4616083A (en) 1986-10-07
FI83476B (fi) 1991-04-15
DE134568T1 (de) 1985-08-29
DK399684A (da) 1985-02-23
ATE38774T1 (de) 1988-12-15
SU1433390A3 (ru) 1988-10-23
ES8505815A1 (es) 1985-06-16
GB2145333B (en) 1987-01-07
GR80147B (en) 1984-12-18
KR850001687A (ko) 1985-04-01
NZ209111A (en) 1987-02-20
FI843261A0 (fi) 1984-08-17
DK399684D0 (da) 1984-08-21

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