ZA842434B - Novel penem compounds,pharmaceutical compositions containing them,processes for their preparation - Google Patents

Novel penem compounds,pharmaceutical compositions containing them,processes for their preparation

Info

Publication number
ZA842434B
ZA842434B ZA842434A ZA842434A ZA842434B ZA 842434 B ZA842434 B ZA 842434B ZA 842434 A ZA842434 A ZA 842434A ZA 842434 A ZA842434 A ZA 842434A ZA 842434 B ZA842434 B ZA 842434B
Authority
ZA
South Africa
Prior art keywords
compositions containing
processes
preparation
pharmaceutical compositions
penem compounds
Prior art date
Application number
ZA842434A
Other languages
English (en)
Inventor
Moopil Girijavallabhan Viyyoor
Kumar Ganguly Ashit
Stuart Walter Mccombie
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of ZA842434B publication Critical patent/ZA842434B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pens And Brushes (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Inks, Pencil-Leads, Or Crayons (AREA)
ZA842434A 1983-04-04 1984-03-30 Novel penem compounds,pharmaceutical compositions containing them,processes for their preparation ZA842434B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/481,551 US4504485A (en) 1983-04-04 1983-04-04 5R,6S,8R-6-(1-Hydroxyethyl)-2-(2-carbamoyloxyethylthio)-penem-3-carboxylic acid

Publications (1)

Publication Number Publication Date
ZA842434B true ZA842434B (en) 1985-08-28

Family

ID=23912395

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA842434A ZA842434B (en) 1983-04-04 1984-03-30 Novel penem compounds,pharmaceutical compositions containing them,processes for their preparation

Country Status (24)

Country Link
US (1) US4504485A (sv)
EP (1) EP0121502B1 (sv)
JP (1) JPS59184185A (sv)
KR (1) KR880001989B1 (sv)
AT (1) ATE26448T1 (sv)
AU (1) AU559521B2 (sv)
CA (1) CA1248520A (sv)
DE (1) DE3463050D1 (sv)
DK (1) DK162286C (sv)
ES (1) ES8602806A1 (sv)
FI (1) FI77867C (sv)
GB (1) GB2138420B (sv)
GR (1) GR81464B (sv)
HK (1) HK59489A (sv)
HU (1) HU193430B (sv)
IE (1) IE57163B1 (sv)
IL (1) IL71413A (sv)
NO (1) NO163133C (sv)
NZ (1) NZ207704A (sv)
OA (1) OA07698A (sv)
PH (1) PH20548A (sv)
PT (1) PT78347B (sv)
SG (1) SG32589G (sv)
ZA (1) ZA842434B (sv)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4634556A (en) * 1985-05-10 1987-01-06 Schering Corporation Crystalline sodium (5R, 6S, 8R)-6-(1-hydroxyethyl)-2-(2-carbamoyloxyethylthio)-penem-3-carboxylate and process for making same
AT392903B (de) * 1987-10-08 1991-07-10 Hoechst Ag Pharmazeutische zubereitung enthaltend ein cephalosporin und ein penemantibiotikum
US4876365A (en) * 1988-12-05 1989-10-24 Schering Corporation Intermediate compounds for preparing penems and carbapenems
DK1142573T3 (da) * 1999-09-17 2006-04-10 Daiichi Asubio Pharma Co Ltd Farmaceutiske præparater omfattende faropenem-natrium og en diaminacetatforbindelse til forbedring af absorption i mave-tarm-kanalen

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4168314A (en) * 1977-11-17 1979-09-18 Merck & Co., Inc. 6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid
IL59081A0 (en) * 1979-01-10 1980-05-30 Schering Corp 2-penem compounds and a method for preparing them
JPS55153789A (en) * 1979-04-11 1980-11-29 Sankyo Co Ltd Penem-3-carboxylic acid derivative and its preparation
US4482565A (en) * 1980-02-22 1984-11-13 Farmitalia Carlo Erba S.P.A. β-Lactam-containing antibacterial agents and β-lactamase inhibitors
ZA815593B (en) * 1980-08-16 1982-10-27 Beecham Group Plc Process for the preparation of 2-thio penem derivatives,certain of these compounds and intermediates therefor
JPS57176988A (en) * 1981-04-09 1982-10-30 Sankyo Co Ltd Penam-3-carboxylic acid derivative and its preparation
JPS5843978A (ja) * 1981-09-10 1983-03-14 Sankyo Co Ltd ペネム−３−カルボン酸誘導体およびその製法

Also Published As

Publication number Publication date
DE3463050D1 (en) 1987-05-14
FI841272A (fi) 1984-10-05
DK174584D0 (da) 1984-03-30
DK174584A (da) 1984-10-05
ES531131A0 (es) 1985-12-01
IE57163B1 (en) 1992-05-20
FI841272A0 (fi) 1984-03-30
FI77867C (sv) 1989-05-10
PH20548A (en) 1987-02-09
NO841292L (no) 1984-10-05
OA07698A (fr) 1985-08-30
NO163133C (no) 1990-04-11
GB2138420A (en) 1984-10-24
IL71413A (en) 1989-01-31
GB2138420B (en) 1986-12-03
CA1248520A (en) 1989-01-10
HU193430B (en) 1987-10-28
GB8408240D0 (en) 1984-05-10
ATE26448T1 (de) 1987-04-15
FI77867B (fi) 1989-01-31
NO163133B (no) 1990-01-02
GR81464B (sv) 1984-12-11
JPS59184185A (ja) 1984-10-19
ES8602806A1 (es) 1985-12-01
HUT34032A (en) 1985-01-28
PT78347A (en) 1984-04-01
KR880001989B1 (ko) 1988-10-10
IL71413A0 (en) 1984-06-29
AU559521B2 (en) 1987-03-12
KR840008369A (ko) 1984-12-14
IE840795L (en) 1984-10-04
NZ207704A (en) 1987-06-30
SG32589G (en) 1989-09-22
EP0121502B1 (en) 1987-04-08
EP0121502A1 (en) 1984-10-10
JPH0470316B2 (sv) 1992-11-10
HK59489A (en) 1989-08-04
DK162286C (da) 1992-03-16
US4504485A (en) 1985-03-12
AU2630984A (en) 1984-10-11
DK162286B (da) 1991-10-07
PT78347B (en) 1986-07-22

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