ES531131A0 - Un procedimiento para preparar acido 5r,6s,8r-6-(1-hidroxietil)-2-(2-carbamoiloxietiltio)-penem-3-carboxilico - Google Patents

Un procedimiento para preparar acido 5r,6s,8r-6-(1-hidroxietil)-2-(2-carbamoiloxietiltio)-penem-3-carboxilico

Info

Publication number
ES531131A0
ES531131A0 ES531131A ES531131A ES531131A0 ES 531131 A0 ES531131 A0 ES 531131A0 ES 531131 A ES531131 A ES 531131A ES 531131 A ES531131 A ES 531131A ES 531131 A0 ES531131 A0 ES 531131A0
Authority
ES
Spain
Prior art keywords
penem
hydroxyethyl
carbamoyloxyethyltio
carboxyllic
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES531131A
Other languages
English (en)
Other versions
ES8602806A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme Corp
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of ES8602806A1 publication Critical patent/ES8602806A1/es
Publication of ES531131A0 publication Critical patent/ES531131A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
ES531131A 1983-04-04 1984-03-30 Un procedimiento para preparar acido 5r,6s,8r-6-(1-hidroxietil)-2-(2-carbamoiloxietiltio)-penem-3-carboxilico Granted ES531131A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/481,551 US4504485A (en) 1983-04-04 1983-04-04 5R,6S,8R-6-(1-Hydroxyethyl)-2-(2-carbamoyloxyethylthio)-penem-3-carboxylic acid

Publications (2)

Publication Number Publication Date
ES8602806A1 ES8602806A1 (es) 1985-12-01
ES531131A0 true ES531131A0 (es) 1985-12-01

Family

ID=23912395

Family Applications (1)

Application Number Title Priority Date Filing Date
ES531131A Granted ES531131A0 (es) 1983-04-04 1984-03-30 Un procedimiento para preparar acido 5r,6s,8r-6-(1-hidroxietil)-2-(2-carbamoiloxietiltio)-penem-3-carboxilico

Country Status (24)

Country Link
US (1) US4504485A (es)
EP (1) EP0121502B1 (es)
JP (1) JPS59184185A (es)
KR (1) KR880001989B1 (es)
AT (1) ATE26448T1 (es)
AU (1) AU559521B2 (es)
CA (1) CA1248520A (es)
DE (1) DE3463050D1 (es)
DK (1) DK162286C (es)
ES (1) ES531131A0 (es)
FI (1) FI77867C (es)
GB (1) GB2138420B (es)
GR (1) GR81464B (es)
HK (1) HK59489A (es)
HU (1) HU193430B (es)
IE (1) IE57163B1 (es)
IL (1) IL71413A (es)
NO (1) NO163133C (es)
NZ (1) NZ207704A (es)
OA (1) OA07698A (es)
PH (1) PH20548A (es)
PT (1) PT78347B (es)
SG (1) SG32589G (es)
ZA (1) ZA842434B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4634556A (en) * 1985-05-10 1987-01-06 Schering Corporation Crystalline sodium (5R, 6S, 8R)-6-(1-hydroxyethyl)-2-(2-carbamoyloxyethylthio)-penem-3-carboxylate and process for making same
AT392903B (de) * 1987-10-08 1991-07-10 Hoechst Ag Pharmazeutische zubereitung enthaltend ein cephalosporin und ein penemantibiotikum
US4876365A (en) * 1988-12-05 1989-10-24 Schering Corporation Intermediate compounds for preparing penems and carbapenems
KR20010101030A (ko) 1999-09-17 2001-11-14 도리이 신이찌로 제약학적 항균 조성물

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4168314A (en) * 1977-11-17 1979-09-18 Merck & Co., Inc. 6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid
IL59081A0 (en) * 1979-01-10 1980-05-30 Schering Corp 2-penem compounds and a method for preparing them
JPS55153789A (en) * 1979-04-11 1980-11-29 Sankyo Co Ltd Penem-3-carboxylic acid derivative and its preparation
US4482565A (en) * 1980-02-22 1984-11-13 Farmitalia Carlo Erba S.P.A. β-Lactam-containing antibacterial agents and β-lactamase inhibitors
ZA815593B (en) * 1980-08-16 1982-10-27 Beecham Group Plc Process for the preparation of 2-thio penem derivatives,certain of these compounds and intermediates therefor
JPS57176988A (en) * 1981-04-09 1982-10-30 Sankyo Co Ltd Penam-3-carboxylic acid derivative and its preparation
JPS5843978A (ja) * 1981-09-10 1983-03-14 Sankyo Co Ltd ペネム−３−カルボン酸誘導体およびその製法

Also Published As

Publication number Publication date
GB2138420A (en) 1984-10-24
DK162286B (da) 1991-10-07
DK174584A (da) 1984-10-05
AU559521B2 (en) 1987-03-12
DK174584D0 (da) 1984-03-30
HK59489A (en) 1989-08-04
IL71413A (en) 1989-01-31
FI841272A (fi) 1984-10-05
KR840008369A (ko) 1984-12-14
EP0121502B1 (en) 1987-04-08
NO163133C (no) 1990-04-11
ES8602806A1 (es) 1985-12-01
GR81464B (es) 1984-12-11
NZ207704A (en) 1987-06-30
FI77867C (fi) 1989-05-10
ATE26448T1 (de) 1987-04-15
FI77867B (fi) 1989-01-31
US4504485A (en) 1985-03-12
PT78347B (en) 1986-07-22
DE3463050D1 (en) 1987-05-14
GB8408240D0 (en) 1984-05-10
IE57163B1 (en) 1992-05-20
NO841292L (no) 1984-10-05
OA07698A (fr) 1985-08-30
DK162286C (da) 1992-03-16
CA1248520A (en) 1989-01-10
IL71413A0 (en) 1984-06-29
ZA842434B (en) 1985-08-28
NO163133B (no) 1990-01-02
JPH0470316B2 (es) 1992-11-10
AU2630984A (en) 1984-10-11
IE840795L (en) 1984-10-04
FI841272A0 (fi) 1984-03-30
PT78347A (en) 1984-04-01
JPS59184185A (ja) 1984-10-19
SG32589G (en) 1989-09-22
PH20548A (en) 1987-02-09
KR880001989B1 (ko) 1988-10-10
GB2138420B (en) 1986-12-03
HU193430B (en) 1987-10-28
EP0121502A1 (en) 1984-10-10
HUT34032A (en) 1985-01-28

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970519