ZA842348B - Pharmaceutical compounds - Google Patents

Pharmaceutical compounds

Info

Publication number
ZA842348B
ZA842348B ZA842348A ZA842348A ZA842348B ZA 842348 B ZA842348 B ZA 842348B ZA 842348 A ZA842348 A ZA 842348A ZA 842348 A ZA842348 A ZA 842348A ZA 842348 B ZA842348 B ZA 842348B
Authority
ZA
South Africa
Prior art keywords
pharmaceutical compounds
pharmaceutical
compounds
Prior art date
Application number
ZA842348A
Other languages
English (en)
Inventor
George Joseph Cullinan
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Publication of ZA842348B publication Critical patent/ZA842348B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04Dimeric indole alkaloids, e.g. vincaleucoblastine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/81Carrier - bound or immobilized peptides or proteins and the preparation thereof, e.g. biological cell or cell fragment as carrier
    • Y10S530/812Peptides or proteins is immobilized on, or in, an organic carrier
    • Y10S530/815Carrier is a synthetic polymer
    • Y10S530/816Attached to the carrier via a bridging agent

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA842348A 1983-03-30 1984-03-29 Pharmaceutical compounds ZA842348B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8308856 1983-03-30

Publications (1)

Publication Number Publication Date
ZA842348B true ZA842348B (en) 1985-06-26

Family

ID=10540515

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA842348A ZA842348B (en) 1983-03-30 1984-03-29 Pharmaceutical compounds

Country Status (24)

Country Link
US (1) US4596676A (de)
EP (1) EP0123441B1 (de)
JP (1) JPS59184189A (de)
KR (1) KR900001165B1 (de)
AR (1) AR241594A1 (de)
AT (1) ATE57187T1 (de)
AU (1) AU560423B2 (de)
BG (1) BG40813A3 (de)
CA (1) CA1225395A (de)
DE (1) DE3483336D1 (de)
DK (1) DK167984A (de)
EG (1) EG16223A (de)
ES (1) ES8506733A1 (de)
FI (1) FI82939C (de)
GR (1) GR79898B (de)
HU (1) HU193283B (de)
IL (1) IL71365A (de)
NZ (1) NZ207674A (de)
PH (1) PH20036A (de)
PL (2) PL142818B1 (de)
PT (1) PT78321B (de)
RU (1) RU1774941C (de)
SU (2) SU1326196A3 (de)
ZA (1) ZA842348B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5476659A (en) * 1982-11-09 1995-12-19 The Scripps Research Institute Cancerous B cell treatment using substituted nucleoside derivatives
GB2137210B (en) * 1983-03-30 1986-11-19 Lilly Industries Ltd Immunoglobulin conjugates
EP0124502B1 (de) * 1983-04-29 1991-06-12 OMNICHEM Société anonyme Konjugierte Vinblastin-Verbindungen und ihre Derivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
US4522750A (en) * 1984-02-21 1985-06-11 Eli Lilly And Company Cytotoxic compositions of transferrin coupled to vinca alkaloids
WO1986005491A1 (en) * 1985-03-12 1986-09-25 The University Of Vermont And State Agricultural C Synthesis of vinblastine and vincristine type compounds
US4675400A (en) * 1985-06-17 1987-06-23 Eli Lilly And Company Bifunctional derivatives of 4-desacetyl indole-dihydroindole alkaloids
EP0232693A3 (de) * 1985-12-16 1988-04-06 La Region Wallonne Konjugate des Vinblastins und seiner Derivate, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
US4801688A (en) * 1986-05-27 1989-01-31 Eli Lilly And Company Hydrazone immunoglobulin conjugates
IL84842A0 (en) * 1986-12-24 1988-06-30 Lilly Co Eli Immunoglobulin conjugates
CA1339775C (en) * 1988-06-10 1998-03-24 Shuzo Matsushita Antibody 0.5b to hiv-i gp 120 modified with toxic substance
US5095109A (en) * 1989-06-08 1992-03-10 University Of Vermont Novel alkaloids
US5043336A (en) * 1990-04-03 1991-08-27 Eli Lilly And Company Cyclic imide derivatives of 4-desacetyl VLB c-3 carboxhydrazide
US5043340A (en) * 1990-04-03 1991-08-27 Eli Lilly And Company Derivatives of 4-desacetyl VLB C-3 carboxhydrazide
JP3100014B2 (ja) * 1991-12-10 2000-10-16 キヤノン株式会社 強誘電性液晶素子及び該素子の製造方法
WO1994011003A1 (en) * 1992-11-13 1994-05-26 The Scripps Research Institute Cancerous b cell treatment using substituted nucleoside derivatives
IL121789A (en) * 1996-10-03 2001-06-14 Rohm & Haas A medicinal product for inhibiting mammalian cell tumors
US20130178618A1 (en) 2012-01-10 2013-07-11 William Allen Boulanger Novel pharmaceutical intermediates and methods for preparing the same

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3392173A (en) * 1964-03-09 1968-07-09 Lilly Co Eli Novel acyl derivatives of desacetyl-vincaleukoblastine and processes for their preparation
US3387001A (en) * 1964-10-19 1968-06-04 Lilly Co Eli Novel aminoacyl esters of desacetyl vincaleukoblastine
GB1541435A (en) * 1975-02-04 1979-02-28 Searle & Co Immunological materials
US4029663A (en) * 1975-07-10 1977-06-14 Eli Lilly And Company Dimeric anhydro-vinca derivatives
US4075214A (en) * 1976-05-17 1978-02-21 Eli Lilly And Company Preparation of leurosidine and novel leurosidine 4'-ethers and esters
US4087429A (en) * 1976-10-20 1978-05-02 Eli Lilly And Company 5' Acetoxy vinblastine 4' bis-sulfite
US4203898A (en) * 1977-08-29 1980-05-20 Eli Lilly And Company Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids
US4122082A (en) * 1977-11-07 1978-10-24 Eli Lilly And Company 4-Desacetoxy-4-oxovinblastine
US4195022A (en) * 1978-03-27 1980-03-25 Eli Lilly And Company 4-Desacetoxy-4α-hydroxyvinblastine and related compounds
US4166810A (en) * 1978-04-20 1979-09-04 Eli Lilly And Company Derivatives of 4-desacetyl VLB C-3 carboxyhydrazide
US4199504A (en) * 1978-05-15 1980-04-22 Eli Lilly And Company Bridged cathranthus alkaloid dimers
OA06421A (fr) * 1980-06-10 1981-09-30 Omnium Chimique Sa Procédé de préparation de dérivés N-(vinblastinoyl-23) d'acides aminés et de peptides.
FI820020L (fi) * 1981-01-12 1982-07-13 Lilly Industries Ltd Immunoglobulinkonjugater
EP0124502B1 (de) * 1983-04-29 1991-06-12 OMNICHEM Société anonyme Konjugierte Vinblastin-Verbindungen und ihre Derivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
US4522750A (en) * 1984-02-21 1985-06-11 Eli Lilly And Company Cytotoxic compositions of transferrin coupled to vinca alkaloids

Also Published As

Publication number Publication date
AU560423B2 (en) 1987-04-09
PT78321B (en) 1986-08-08
PL246932A1 (en) 1985-12-03
KR900001165B1 (ko) 1990-02-27
KR840008161A (ko) 1984-12-13
AU2614484A (en) 1984-10-04
SU1326196A3 (ru) 1987-07-23
EG16223A (en) 1990-12-30
ATE57187T1 (de) 1990-10-15
EP0123441B1 (de) 1990-10-03
GR79898B (de) 1984-10-31
PT78321A (en) 1984-04-01
NZ207674A (en) 1987-11-27
JPS59184189A (ja) 1984-10-19
PL142754B1 (en) 1987-11-30
PH20036A (en) 1986-09-04
ES531080A0 (es) 1985-07-16
PL254899A1 (en) 1986-06-17
FI841259A0 (fi) 1984-03-29
FI82939B (fi) 1991-01-31
CA1225395A (en) 1987-08-11
ES8506733A1 (es) 1985-07-16
HU193283B (en) 1987-09-28
DK167984D0 (da) 1984-03-26
IL71365A (en) 1988-05-31
PL142818B1 (en) 1987-12-31
IL71365A0 (en) 1984-06-29
EP0123441A1 (de) 1984-10-31
FI82939C (fi) 1991-05-10
DE3483336D1 (de) 1990-11-08
DK167984A (da) 1984-10-01
US4596676A (en) 1986-06-24
RU1774941C (ru) 1992-11-07
AR241594A1 (es) 1992-09-30
FI841259A (fi) 1984-10-01
SU1491341A3 (ru) 1989-06-30
BG40813A3 (en) 1987-02-16

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