ZA83541B - New derivatives of 2-piperazinyl 4-phenyl quinazoline having antidepressant properties, process for preparing said compounds and drugs containing same - Google Patents

New derivatives of 2-piperazinyl 4-phenyl quinazoline having antidepressant properties, process for preparing said compounds and drugs containing same

Info

Publication number
ZA83541B
ZA83541B ZA83541A ZA83541A ZA83541B ZA 83541 B ZA83541 B ZA 83541B ZA 83541 A ZA83541 A ZA 83541A ZA 83541 A ZA83541 A ZA 83541A ZA 83541 B ZA83541 B ZA 83541B
Authority
ZA
South Africa
Prior art keywords
preparing
piperazinyl
compounds
new derivatives
drugs containing
Prior art date
Application number
ZA83541A
Other languages
English (en)
Inventor
Kathleen Biziere
Andre Hallot
Jean-Paul Kan
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of ZA83541B publication Critical patent/ZA83541B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/78Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C07D239/84Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/78Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
ZA83541A 1982-02-08 1983-01-27 New derivatives of 2-piperazinyl 4-phenyl quinazoline having antidepressant properties, process for preparing said compounds and drugs containing same ZA83541B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8201988A FR2521144A1 (fr) 1982-02-08 1982-02-08 Nouveaux derives de la piperazinyl-2 phenyl-4 quinazoline possedant des proprietes antidepressives, methode de preparation desdits composes et medicaments en contenant

Publications (1)

Publication Number Publication Date
ZA83541B true ZA83541B (en) 1983-10-26

Family

ID=9270762

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA83541A ZA83541B (en) 1982-02-08 1983-01-27 New derivatives of 2-piperazinyl 4-phenyl quinazoline having antidepressant properties, process for preparing said compounds and drugs containing same

Country Status (30)

Country Link
US (1) US4540696A (sv)
EP (1) EP0087337B1 (sv)
JP (1) JPS58146573A (sv)
KR (1) KR900003301B1 (sv)
AT (1) ATE19244T1 (sv)
AU (1) AU554802B2 (sv)
CA (1) CA1249274A (sv)
CS (1) CS228944B2 (sv)
DD (1) DD209457A5 (sv)
DE (1) DE3362999D1 (sv)
DK (1) DK154972C (sv)
EG (1) EG15649A (sv)
ES (1) ES8401060A1 (sv)
FI (1) FI73983C (sv)
FR (1) FR2521144A1 (sv)
GR (1) GR76744B (sv)
HU (1) HU190710B (sv)
IE (1) IE54427B1 (sv)
IL (1) IL67746A (sv)
MA (1) MA19696A1 (sv)
NO (1) NO159171C (sv)
NZ (1) NZ203209A (sv)
OA (1) OA07320A (sv)
PH (1) PH18862A (sv)
PL (1) PL138118B1 (sv)
PT (1) PT76146A (sv)
SG (1) SG2089G (sv)
SU (1) SU1287750A3 (sv)
YU (1) YU30183A (sv)
ZA (1) ZA83541B (sv)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2521144A1 (fr) * 1982-02-08 1983-08-12 Sanofi Sa Nouveaux derives de la piperazinyl-2 phenyl-4 quinazoline possedant des proprietes antidepressives, methode de preparation desdits composes et medicaments en contenant
JPS60146891A (ja) * 1984-01-05 1985-08-02 Mitsubishi Chem Ind Ltd 〔2,3−d〕チエノピリミジン誘導体およびその塩
JPS6165873A (ja) * 1984-09-07 1986-04-04 Mitsui Petrochem Ind Ltd 2−ピペラジノピリミジン誘導体
EP1618094B1 (en) * 2003-04-30 2007-09-05 The Institutes for Pharmaceutical Discovery, LLC Substituted heteroaryls as inhibitors of protein tyrosine phosphatases
MXPA06005019A (es) * 2003-11-03 2006-07-06 Warner Lambert Co Nuevos inhibidores de la recaptacion de norpinefrina para el tratamiento de transtornos del sistema nervioso central.
AU2004289303A1 (en) * 2003-11-10 2005-05-26 Synta Pharmaceuticals, Corp. Fused heterocyclic compounds
JP4796622B2 (ja) * 2005-04-11 2011-10-19 エフ.ホフマン−ラ ロシュ アーゲー (3,4−ジヒドロ−キナゾリン−2−イル)−インダン−1−イル−アミン

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3305553A (en) * 1965-10-18 1967-02-21 Parke Davis & Co 2-aminoquinazoline derivatives
US3509141A (en) * 1966-09-15 1970-04-28 Ciba Geigy Corp 2-amino-quinazolines
US3646028A (en) * 1966-09-15 1972-02-29 Ciba Geigy Corp Certain 2-amino-4-phenyl-3 4-dihydroquinazolines
US3511836A (en) * 1967-12-13 1970-05-12 Pfizer & Co C 2,4,6,7-tetra substituted quinazolines
US3635979A (en) * 1969-09-29 1972-01-18 Pfizer Certain 6- and/or 7-alkoxy-substituted-2 4-bis(disubstituted amino) quinazolines
JPS5692875A (en) * 1979-12-27 1981-07-27 Dainippon Pharmaceut Co Ltd 2-aminoquinazoline derivative
JPS56118421A (en) * 1980-02-25 1981-09-17 Nitto Electric Ind Co Ltd Heat-shrinkable polyimide film and production thereof
FR2514765A1 (fr) * 1981-10-21 1983-04-22 Sanofi Sa Nouveaux derives de la phenyl-4 quinazoline actifs sur le systeme nerveux central
FR2521144A1 (fr) * 1982-02-08 1983-08-12 Sanofi Sa Nouveaux derives de la piperazinyl-2 phenyl-4 quinazoline possedant des proprietes antidepressives, methode de preparation desdits composes et medicaments en contenant

Also Published As

Publication number Publication date
FI73983C (sv) 1987-12-10
DD209457A5 (de) 1984-05-09
AU1117683A (en) 1983-08-18
MA19696A1 (fr) 1983-10-01
OA07320A (fr) 1984-08-31
FI830338L (fi) 1983-08-09
NO159171C (no) 1988-12-07
KR900003301B1 (ko) 1990-05-14
SG2089G (en) 1989-06-02
PL138118B1 (en) 1986-08-30
DK154972C (da) 1989-06-12
IE54427B1 (en) 1989-10-11
NO830398L (no) 1983-08-09
IL67746A0 (en) 1983-05-15
AU554802B2 (en) 1986-09-04
CS228944B2 (en) 1984-05-14
IL67746A (en) 1986-08-31
ES519598A0 (es) 1983-11-16
CA1249274A (en) 1989-01-24
SU1287750A3 (ru) 1987-01-30
NO159171B (no) 1988-08-29
DK50383A (da) 1983-08-09
PH18862A (en) 1985-10-21
NZ203209A (en) 1985-07-12
DE3362999D1 (en) 1986-05-22
EP0087337A1 (fr) 1983-08-31
KR840003627A (ko) 1984-09-15
YU30183A (en) 1985-10-31
HU190710B (en) 1986-10-28
US4540696A (en) 1985-09-10
EP0087337B1 (fr) 1986-04-16
EG15649A (en) 1986-09-30
ES8401060A1 (es) 1983-11-16
FI73983B (fi) 1987-08-31
JPS58146573A (ja) 1983-09-01
FI830338A0 (fi) 1983-02-01
PL240469A1 (en) 1983-11-21
ATE19244T1 (de) 1986-05-15
PT76146A (fr) 1983-02-01
FR2521144B1 (sv) 1984-11-09
FR2521144A1 (fr) 1983-08-12
IE830111L (en) 1983-08-08
GR76744B (sv) 1984-08-30
DK154972B (da) 1989-01-16
DK50383D0 (da) 1983-02-07

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