ZA807704B - 2-acylaminomethyl-1,4-benzodiazepines and salts thereof,methods of preparing them and preparations containing these compounds - Google Patents
2-acylaminomethyl-1,4-benzodiazepines and salts thereof,methods of preparing them and preparations containing these compoundsInfo
- Publication number
- ZA807704B ZA807704B ZA00807704A ZA807704A ZA807704B ZA 807704 B ZA807704 B ZA 807704B ZA 00807704 A ZA00807704 A ZA 00807704A ZA 807704 A ZA807704 A ZA 807704A ZA 807704 B ZA807704 B ZA 807704B
- Authority
- ZA
- South Africa
- Prior art keywords
- acylaminomethyl
- benzodiazepines
- salts
- preparing
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D245/00—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms
- C07D245/04—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
- C07D245/06—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19792952279 DE2952279A1 (de) | 1979-12-24 | 1979-12-24 | Neue 2-acylaminomethyl-1,4-benzodiazepine und deren salze sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA807704B true ZA807704B (en) | 1981-11-25 |
Family
ID=6089628
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA00807704A ZA807704B (en) | 1979-12-24 | 1980-12-09 | 2-acylaminomethyl-1,4-benzodiazepines and salts thereof,methods of preparing them and preparations containing these compounds |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US4325957A (fi) |
| EP (1) | EP0031080B1 (fi) |
| JP (1) | JPS5699477A (fi) |
| AU (1) | AU542701B2 (fi) |
| CA (1) | CA1169425A (fi) |
| DD (2) | DD155988A5 (fi) |
| DE (3) | DE2952279A1 (fi) |
| DK (1) | DK548080A (fi) |
| ES (2) | ES8201142A1 (fi) |
| FI (1) | FI68050C (fi) |
| GR (1) | GR73080B (fi) |
| HU (1) | HU185398B (fi) |
| IE (1) | IE50580B1 (fi) |
| IL (1) | IL61692A (fi) |
| NO (1) | NO154883C (fi) |
| NZ (1) | NZ195872A (fi) |
| PH (1) | PH17189A (fi) |
| PT (2) | PT72278B (fi) |
| SU (1) | SU1253430A3 (fi) |
| YU (1) | YU324780A (fi) |
| ZA (1) | ZA807704B (fi) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3021107A1 (de) * | 1980-06-04 | 1981-12-17 | Hoechst Ag, 6000 Frankfurt | Carbamoyloxyamino-1,4-benzodiazepine, verfahren zu irer herstellung und diese enthaltende arzneimittel |
| DE3048264A1 (de) * | 1980-12-20 | 1982-09-09 | Kali-Chemie Pharma Gmbh, 3000 Hannover | 2-acylaminomethyl-1,4-benzodiazepine und deren salze sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DE3124013A1 (de) * | 1981-06-19 | 1982-12-30 | Kali-Chemie Pharma Gmbh, 3000 Hannover | 2-acylaminomethyl-1,4-benzodiazepin-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DE3151597A1 (de) * | 1981-12-28 | 1983-07-07 | Kali-Chemie Pharma Gmbh, 3000 Hannover | (1,2)-anellierte 1,4-benzodiazepin-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| US4684646A (en) * | 1984-06-26 | 1987-08-04 | Merck & Co., Inc. | 2-acylaminomethyl-1,4-benzodiazepine derivatives as CCK-antagonists |
| US4724237A (en) * | 1984-06-26 | 1988-02-09 | Merck & Co., Inc. | 2-substituted-aminomethyl-1,4-benzodiazepines |
| EP0170024A3 (en) * | 1984-06-26 | 1990-01-31 | Merck & Co. Inc. | Use of 2-acylaminomethyl-1,4-benzodiazepine derivatives for the production of pharmaceutical compositions and process for the preparation for pharmaceutical compositions |
| JPH01314666A (ja) * | 1988-06-15 | 1989-12-19 | Kayaba Ind Co Ltd | パワーステアリング装置の操舵力制御装置 |
| GB8823041D0 (en) * | 1988-09-30 | 1988-11-09 | Lilly Sa | Organic compounds & their use as pharmaceuticals |
| GB8823042D0 (en) * | 1988-09-30 | 1988-11-09 | Lilly Sa | Organic compounds & their use as pharmaceuticals |
| US5380721A (en) * | 1990-09-10 | 1995-01-10 | Sterling Winthrop Inc. | Aryl-fused and hetaryl-fused-2,4-diazepine and 2,4-diazocine antiarrhythmic agents |
| JPH0546660U (ja) * | 1991-12-03 | 1993-06-22 | カヤバ工業株式会社 | パワーステアリング装置 |
| AU7072200A (en) * | 1999-08-27 | 2001-03-26 | Procter & Gamble Company, The | Fast-acting formulation components, compositions and laundry methods employing same |
| US6825160B1 (en) | 1999-08-27 | 2004-11-30 | Procter & Gamble Company | Color safe laundry methods employing cationic formulation components |
| US6818607B1 (en) | 1999-08-27 | 2004-11-16 | Procter & Gamble Company | Bleach boosting components, compositions and laundry methods |
| US6821935B1 (en) | 1999-08-27 | 2004-11-23 | Procter & Gamble Company | Color safe laundry methods employing zwitterionic formulation components |
| MXPA02002125A (es) * | 1999-08-27 | 2002-09-18 | Procter & Gamble | Componentes aumentadores del blanqueado, composiciones y metodos de lavanderia. |
| US7109156B1 (en) | 1999-08-27 | 2006-09-19 | Procter & Gamble Company | Controlled availability of formulation components, compositions and laundry methods employing same |
| JP2003508587A (ja) | 1999-08-27 | 2003-03-04 | ザ、プロクター、エンド、ギャンブル、カンパニー | 安定性増強配合成分、これを用いた組成物および洗濯方法 |
| US6903060B1 (en) | 1999-08-27 | 2005-06-07 | Procter & Gamble Company | Stable formulation components, compositions and laundry methods employing same |
| US7169744B2 (en) * | 2002-06-06 | 2007-01-30 | Procter & Gamble Company | Organic catalyst with enhanced solubility |
| US7557076B2 (en) | 2002-06-06 | 2009-07-07 | The Procter & Gamble Company | Organic catalyst with enhanced enzyme compatibility |
| US20050113246A1 (en) * | 2003-11-06 | 2005-05-26 | The Procter & Gamble Company | Process of producing an organic catalyst |
| AR051659A1 (es) * | 2005-06-17 | 2007-01-31 | Procter & Gamble | Una composicion que comprende un catalizador organico con compatibilidada enzimatica mejorada |
| KR100877824B1 (ko) | 2005-11-11 | 2009-01-12 | 한국생명공학연구원 | Ｅ2ｅｐｆ ｕｃｐ-ｖｈｌ 상호작용 및 그 용도 |
| CN113149914A (zh) * | 2021-01-15 | 2021-07-23 | 福安药业集团重庆礼邦药物开发有限公司 | 一种咪达唑仑中间体脱氟杂质的制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3681340A (en) * | 1968-02-12 | 1972-08-01 | Herman Robert Rodriguez | 1,3-benzodiazepines |
| US3738999A (en) * | 1970-05-28 | 1973-06-12 | Squibb & Sons Inc | 2,3,4,5-tetrahydro-2-phenyl-1,4-benzothiazepine, hydrochloride |
| DE2353160C2 (de) * | 1973-05-02 | 1986-07-17 | Kali-Chemie Ag, 3000 Hannover | 5-Phenyl-2,3-dihydro-1H-1,4-benzodiazepine, ihre Säureadditionssalze und diese Verbindungen enthaltende Arzneimittel |
| DE2353187A1 (de) * | 1973-05-02 | 1974-11-14 | Kali Chemie Ag | Neue benzodiazepinderivate |
| US3925358A (en) * | 1973-07-27 | 1975-12-09 | Hoffmann La Roche | 1-Lower alkyl-2-substituted-1,4-benzodiazepines |
| US3947475A (en) * | 1975-04-28 | 1976-03-30 | Stauffer Chemical Company | 5-Furoyl-2,2,4-trimethyl-1,4-dihydro-1H-1,5-benzodiazepine as an anti-inflammatory agent |
| US4087421A (en) * | 1976-04-19 | 1978-05-02 | American Cyanamid Company | Substituted benzodiazepines and method of use |
-
1979
- 1979-12-24 DE DE19792952279 patent/DE2952279A1/de not_active Withdrawn
-
1980
- 1980-10-20 GR GR63733A patent/GR73080B/el unknown
- 1980-12-04 IE IE2531/80A patent/IE50580B1/en unknown
- 1980-12-09 ZA ZA00807704A patent/ZA807704B/xx unknown
- 1980-12-10 EP EP80107779A patent/EP0031080B1/de not_active Expired
- 1980-12-10 DE DE8080107779T patent/DE3064983D1/de not_active Expired
- 1980-12-10 DE DE8282107036T patent/DE3070798D1/de not_active Expired
- 1980-12-11 IL IL61692A patent/IL61692A/xx unknown
- 1980-12-16 PH PH24988A patent/PH17189A/en unknown
- 1980-12-17 HU HU803023A patent/HU185398B/hu unknown
- 1980-12-18 NZ NZ195872A patent/NZ195872A/xx unknown
- 1980-12-19 FI FI803988A patent/FI68050C/fi not_active IP Right Cessation
- 1980-12-22 YU YU03247/80A patent/YU324780A/xx unknown
- 1980-12-22 DK DK548080A patent/DK548080A/da not_active Application Discontinuation
- 1980-12-22 DD DD80226419A patent/DD155988A5/de unknown
- 1980-12-22 DD DD80233407A patent/DD200274A5/de unknown
- 1980-12-22 SU SU3220053A patent/SU1253430A3/ru active
- 1980-12-22 AU AU65664/80A patent/AU542701B2/en not_active Ceased
- 1980-12-23 CA CA000367417A patent/CA1169425A/en not_active Expired
- 1980-12-23 ES ES498071A patent/ES8201142A1/es not_active Expired
- 1980-12-23 NO NO803935A patent/NO154883C/no unknown
- 1980-12-23 ES ES498072A patent/ES8201143A1/es not_active Expired
- 1980-12-23 US US06/219,487 patent/US4325957A/en not_active Expired - Lifetime
- 1980-12-23 PT PT72278A patent/PT72278B/pt unknown
- 1980-12-23 PT PT72279A patent/PT72279B/pt unknown
- 1980-12-24 JP JP18216980A patent/JPS5699477A/ja active Granted
-
1982
- 1982-01-12 US US06/338,883 patent/US4382030A/en not_active Expired - Fee Related
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ZA807704B (en) | 2-acylaminomethyl-1,4-benzodiazepines and salts thereof,methods of preparing them and preparations containing these compounds | |
| DE2960553D1 (en) | Derivatives of carbazolyl-4-oxypropanolamine, methods for their preparation and medicines containing them | |
| DE3062971D1 (en) | Derivatives of tetraline, their preparation and medicaments containing these compounds | |
| DE2861809D1 (en) | Corticoids-17-alkylcarbonates, process for their preparation and preparations containing them | |
| PH16099A (en) | Guanidinothiazole compounds,process for preparing them and medical composition containing them | |
| IL60890A0 (en) | Preparations for the treatment of theileriosic containing piperidyl acetonyl-quinazolinone deravatives and some new such compounds | |
| DE3060268D1 (en) | N-substituted 2-cyanaziridines, methods for their preparation and medicaments containing them, correspondingly substituted aziridine-2-carbonamides and their preparation | |
| IL60904A0 (en) | Preparation of 1a-hydrovitamin d compounds form 1a-hydroxy-3,5-cyclovitamin d compounds | |
| GB2063870B (en) | 1-aryl-4-arylsulphonyl-1h-pyrazolol-3 compounds and processes for their preparation | |
| DE3061010D1 (en) | Substituted acetophenones, preparations containing them and processes for their preparation | |
| IL61016A0 (en) | Oxazolidone and thiazolidone derivatives,their preparation and acaricidal derivatives containing them | |
| DE3067258D1 (en) | Substituted 3-amino-sydnonimines, process for their synthesis and pharmaceutical preparations containing them | |
| DE3071581D1 (en) | Substituted tetraazatricyclic compounds, process for their preparation, their use and medicines containing them | |
| DE3065163D1 (en) | New 4-fluoro-3-phenoxy-benzyl-ethers, process for their preparation and their use | |
| NZ193078A (en) | Derivatives of 9-aminoalkyl-flyorene medicinal preparations | |
| IL60546A (en) | Preparation of 2,6-dialkylcyclohexylamines | |
| NZ193324A (en) | Preparation of n2-phenyl-2,6-diaminonebularines | |
| HU178340B (en) | Process for preparing new pharmaceutical preparations containing aryloxy-alkanolamine and monoalkylsulphate | |
| IL60080A (en) | Derivatives of 3-phenyl-2-dihydrothiazol-2-ylidene-3-oxo-propionitrile,process for their preparation,insecticidal preparations and methods for using them | |
| ZA793667B (en) | N-arylsulfonylpyrroles,their preparation,and therapeutic agents containing these compounds | |
| DE3378208D1 (en) | Substituted azabicycloalkanes, their use, pharmaceutical preparations containing these compounds and process for preparing these compounds | |
| GB2048868B (en) | Preparation of 2',6'-dialkyl - n - alkoxymethyl - 2 - chloroacetanilides | |
| PT71498A (en) | Process for preparing aminothiadiazolyl compounds and pharmaceutical preparations containing such compounds | |
| GB2041374B (en) | Halogenated -lactam compounds and process for their preparation | |
| ZA803879B (en) | Heterocyclic compounds, processes for their preparation and their use |