ZA801483B - Peptides having ubiquitin-like activity - Google Patents

Peptides having ubiquitin-like activity

Info

Publication number
ZA801483B
ZA801483B ZA00801483A ZA801483A ZA801483B ZA 801483 B ZA801483 B ZA 801483B ZA 00801483 A ZA00801483 A ZA 00801483A ZA 801483 A ZA801483 A ZA 801483A ZA 801483 B ZA801483 B ZA 801483B
Authority
ZA
South Africa
Prior art keywords
sub
lys
peptides
activity
ubiquitin
Prior art date
Application number
ZA00801483A
Other languages
English (en)
Inventor
G Heavner
G Goldstein
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of ZA801483B publication Critical patent/ZA801483B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/66—Thymopoietins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ZA00801483A 1979-03-14 1980-03-13 Peptides having ubiquitin-like activity ZA801483B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/020,157 US4215111A (en) 1979-03-14 1979-03-14 Peptides having ubiquitin-like activity

Publications (1)

Publication Number Publication Date
ZA801483B true ZA801483B (en) 1981-10-28

Family

ID=21797065

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00801483A ZA801483B (en) 1979-03-14 1980-03-13 Peptides having ubiquitin-like activity

Country Status (18)

Country Link
US (1) US4215111A (de)
EP (1) EP0016612B1 (de)
JP (1) JPS55143946A (de)
AT (1) ATE1856T1 (de)
AU (1) AU544923B2 (de)
CA (1) CA1146166A (de)
DE (1) DE3061127D1 (de)
DK (1) DK149091C (de)
ES (1) ES489521A0 (de)
FI (1) FI67691C (de)
GR (1) GR68038B (de)
IE (1) IE49423B1 (de)
IL (1) IL59603A (de)
NO (1) NO149998C (de)
NZ (1) NZ193077A (de)
PT (1) PT70948B (de)
YU (1) YU41913B (de)
ZA (1) ZA801483B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4369137A (en) * 1980-06-17 1983-01-18 Ortho Pharmaceutical Corporation N-Protected pentapeptides useful as intermediates in the preparation of thymopoietin pentapeptide
US4298523A (en) * 1980-06-17 1981-11-03 Ortho Pharmaceutical Corporation Methods and compositions for preparation of H-ARG-X-Z-Y-TYR-R
US4289759A (en) * 1980-06-23 1981-09-15 Ortho Pharmaceutical Corporation Immunoregulatory diketopiperazine compounds
US4481191A (en) * 1983-03-30 1984-11-06 The Regents Of The University Of California Method for controlling blood pressure
WO1986004334A1 (en) * 1985-01-18 1986-07-31 MERCK Patent Gesellschaft mit beschränkter Haftung Immunoregulatory peptides
JPH01104193A (ja) * 1986-06-10 1989-04-21 Kyowa Hakko Kogyo Co Ltd 新規ポリペプチド
US6258550B1 (en) 1993-04-23 2001-07-10 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site
WO1994025482A1 (en) * 1993-04-23 1994-11-10 Evans Herbert J Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site
US5965698A (en) * 1993-04-23 1999-10-12 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein--protein interaction site
US5952465A (en) * 1993-04-23 1999-09-14 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site
US5928896A (en) * 1993-04-23 1999-07-27 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein--protein interaction site
US6084066A (en) * 1993-10-29 2000-07-04 Virginia Commonwealth University Polypetides that include conformation-constraining groups which flank a protein-protein interaction site
US5770720A (en) * 1995-08-30 1998-06-23 Barnes-Jewish Hospital Ubiquitin conjugating enzymes having transcriptional repressor activity

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4113858A (en) * 1975-01-20 1978-09-12 St. Luke's Hospital Novel compounds, compositions and methods of their use
FR2391994A1 (fr) * 1977-05-25 1978-12-22 Anvar Nouveaux polypeptides a activite thymique ou a activite antagoniste et leurs procedes de synthese
SE446866B (sv) * 1977-11-15 1986-10-13 Sloan Kettering Inst Cancer Sett att framstella en aktiv polypeptid med formaga att inducera differentiering av bade t-lymfocyter och komplementreceptor (cr?72+) b-lymfocyter
SE446867B (sv) * 1977-11-15 1986-10-13 Sloan Kettering Inst Cancer Sett att framstella en polypeptid med formaga att inducera differentiering av t-lymfocyter men inte av komplementreceptor (cr?72+) b-lymfocyter
NZ189101A (en) * 1977-12-08 1984-07-06 Ortho Pharma Corp Polypeptides having the ability to induce differentiation of both th-1+ t-lymphocytes and bu-1+ b-lymphocytes;pharmaceutical compositions

Also Published As

Publication number Publication date
NO149998B (no) 1984-04-24
DK149091C (da) 1986-06-16
AU544923B2 (en) 1985-06-20
US4215111A (en) 1980-07-29
FI800779A (fi) 1980-09-15
ES8103026A1 (es) 1981-02-16
NZ193077A (en) 1984-05-31
AU5631380A (en) 1980-09-18
EP0016612A3 (en) 1981-01-07
NO149998C (no) 1984-08-01
IE800515L (en) 1980-09-14
EP0016612B1 (de) 1982-11-24
DK109180A (da) 1980-09-15
IE49423B1 (en) 1985-10-02
YU41913B (en) 1988-02-29
GR68038B (de) 1981-10-27
FI67691C (fi) 1985-05-10
DK149091B (da) 1986-01-20
JPH0153268B2 (de) 1989-11-13
CA1146166A (en) 1983-05-10
ES489521A0 (es) 1981-02-16
PT70948A (en) 1980-04-01
IL59603A (en) 1983-02-23
YU65980A (en) 1984-02-29
FI67691B (fi) 1985-01-31
ATE1856T1 (de) 1982-12-15
NO800724L (no) 1980-09-15
DE3061127D1 (en) 1982-12-30
IL59603A0 (en) 1980-06-30
JPS55143946A (en) 1980-11-10
PT70948B (en) 1981-06-24
EP0016612A2 (de) 1980-10-01

Similar Documents

Publication Publication Date Title
ES485104A1 (es) Procedimiento para preparar derivados de ciclosporina
ES477832A1 (es) Un procedimiento para la preparacion de derivados de diben- zopirano.
PT70948A (en) Peptides having ubiquitin-like-activity
ES8101530A1 (es) Un procedimiento para la preparacion de alcoholes beta-gama-dihidro-poliprenilicos.
IE44573L (en) N-(1,3,4-thiadiazol-2-yl) benzamides
IE781291L (en) Psychopharmacological peptides
JPS6431752A (en) Amide derivative and skin external preparation containing said derivative
ES467886A1 (es) Procedimiento para la preparacion de derivados de acido oleanoico.
ES448645A1 (es) Un procedimiento de preparacion de nuevos derivados de ci- clopropanol.
ES476837A1 (es) Procedimientos de preparar derivados pirimidinicos condensa-dos con cabeza de puente de nitrogeno.
ES475345A1 (es) Un procedimiento para la preparacion de diclorovinilciclobu-tanonas
JPS53130693A (en) Antibiotic substance c-15003
JPS5422326A (en) 3-trimethylsilymethyl-3-butenoic acid and its preparation
ES8403102A1 (es) Un procedimiento para la preparacion de esteres fluorofenoxibencilicos.
JPS5427581A (en) P1-s-phenylthiop2-nucleoside 5'-pyrophosphates and their preparation
JPS5432494A (en) Novel cycloimidazoline riboside derivatives and their preparation
JPS5414992A (en) Novel cyclopropylmethylamine derivative and its preparation
JPS5279081A (en) Preparation of novel 7-methoxycephalosporins
JPS5265256A (en) Synthesis of 6,7-exo-trimethylene-bicyclo 3,2,1 -oct-2-ene
JPS5412361A (en) Novel compound and its preparation
JPS5429327A (en) Bispiropirazine compound, its preparation, and its use as pigment
JPS5439072A (en) Peptides
JPS52136149A (en) 3-epi-xk-88-5 as novel antibiotics and its preparation
JPS5283823A (en) Naphthohydroxamates
JPS5326332A (en) Anti-suntan cosmetics