ZA791726B - Benzimidazole and benzimidazolidine derivatives with diuretic and antihypertensive activity - Google Patents

Benzimidazole and benzimidazolidine derivatives with diuretic and antihypertensive activity

Info

Publication number
ZA791726B
ZA791726B ZA791726A ZA791726A ZA791726B ZA 791726 B ZA791726 B ZA 791726B ZA 791726 A ZA791726 A ZA 791726A ZA 791726 A ZA791726 A ZA 791726A ZA 791726 B ZA791726 B ZA 791726B
Authority
ZA
South Africa
Prior art keywords
benzimidazolidine
diuretic
benzimidazole
derivatives
antihypertensive activity
Prior art date
Application number
ZA791726A
Other languages
English (en)
Inventor
B Shetty
A Mcfadden
Original Assignee
Mundipharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mundipharma Ag filed Critical Mundipharma Ag
Publication of ZA791726B publication Critical patent/ZA791726B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA791726A 1978-04-10 1979-04-10 Benzimidazole and benzimidazolidine derivatives with diuretic and antihypertensive activity ZA791726B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US89504878A 1978-04-10 1978-04-10

Publications (1)

Publication Number Publication Date
ZA791726B true ZA791726B (en) 1980-05-28

Family

ID=25403870

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA791726A ZA791726B (en) 1978-04-10 1979-04-10 Benzimidazole and benzimidazolidine derivatives with diuretic and antihypertensive activity

Country Status (19)

Country Link
JP (1) JPS54138561A (sv)
AT (1) AT372951B (sv)
AU (1) AU531086B2 (sv)
BE (1) BE875425A (sv)
CA (1) CA1126280A (sv)
DE (1) DE2914084A1 (sv)
DK (1) DK139079A (sv)
ES (1) ES479446A1 (sv)
FI (1) FI74461C (sv)
FR (1) FR2422644A1 (sv)
GB (1) GB2018766B (sv)
GR (1) GR68483B (sv)
IL (1) IL57105A (sv)
IT (1) IT1193755B (sv)
NL (1) NL7902802A (sv)
NZ (1) NZ190136A (sv)
PT (1) PT69458A (sv)
SE (1) SE446532B (sv)
ZA (1) ZA791726B (sv)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102070466A (zh) * 2010-12-28 2011-05-25 天津市筠凯化工科技有限公司 5-氯-2-硝基苯胺制备方法
CN108558712A (zh) * 2018-06-20 2018-09-21 新乡市锦源化工有限公司 一种以乙酰苯胺为原料合成高纯度对氨基苯磺酰胺的方法及对氨基苯磺酰胺
CN110305018B (zh) * 2019-06-06 2022-07-15 浙江普洛家园药业有限公司 一种3-溴-2-氟硝基苯的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH404675A (de) * 1961-06-29 1965-12-31 Siegfried Ag Verfahren zur Herstellung neuer heterocyclischer Sulfonamidoverbindungen
FR1469504A (fr) * 1964-10-22 1967-02-17 Fisons Pest Control Ltd Composés insecticides
FR1477792A (fr) * 1965-03-24 1967-04-21 Fisons Pest Control Ltd Nouveaux benzimidazoles
GB1163711A (en) * 1966-01-13 1969-09-10 Fisons Pest Control Ltd Substituted Benzimidazoles and Biocidally-Active Compositions
GB1356244A (en) * 1970-07-29 1974-06-12 Fisons Ltd Substituted benzimidazole parasiticides

Also Published As

Publication number Publication date
SE7902911L (sv) 1979-10-11
DK139079A (da) 1979-10-11
FI74461B (fi) 1987-10-30
IL57105A0 (en) 1979-07-25
AU531086B2 (en) 1983-08-11
GB2018766A (en) 1979-10-24
JPH0250904B2 (sv) 1990-11-05
IL57105A (en) 1983-10-31
FI791083A (fi) 1979-10-11
FR2422644A1 (fr) 1979-11-09
AU4567579A (en) 1979-10-18
IT7948686A0 (it) 1979-04-10
NZ190136A (en) 1982-11-23
GR68483B (sv) 1982-01-04
CA1126280A (en) 1982-06-22
GB2018766B (en) 1982-09-22
DE2914084A1 (de) 1979-10-25
FR2422644B1 (sv) 1982-12-17
SE446532B (sv) 1986-09-22
BE875425A (fr) 1979-07-31
AT372951B (de) 1983-12-12
FI74461C (sv) 1988-02-08
PT69458A (en) 1979-05-01
ATA263379A (de) 1983-04-15
IT1193755B (it) 1988-08-24
NL7902802A (nl) 1979-10-12
ES479446A1 (es) 1979-08-01
JPS54138561A (en) 1979-10-27

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