ZA785335B - Xanthine derivatives - Google Patents

Xanthine derivatives

Info

Publication number
ZA785335B
ZA785335B ZA00785335A ZA785335A ZA785335B ZA 785335 B ZA785335 B ZA 785335B ZA 00785335 A ZA00785335 A ZA 00785335A ZA 785335 A ZA785335 A ZA 785335A ZA 785335 B ZA785335 B ZA 785335B
Authority
ZA
South Africa
Prior art keywords
xanthine derivatives
xanthine
derivatives
Prior art date
Application number
ZA00785335A
Other languages
English (en)
Inventor
L Sorenby
P Kjellin
S Bergstrand
C Persson
Original Assignee
Draco Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Draco Ab filed Critical Draco Ab
Publication of ZA785335B publication Critical patent/ZA785335B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
ZA00785335A 1977-10-14 1978-09-19 Xanthine derivatives ZA785335B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7711581A SE416810C (sv) 1977-10-14 1977-10-14 Forfarande for framstellning av xantinderivat med antiallergisk aktivitet

Publications (1)

Publication Number Publication Date
ZA785335B true ZA785335B (en) 1979-09-26

Family

ID=20332576

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00785335A ZA785335B (en) 1977-10-14 1978-09-19 Xanthine derivatives

Country Status (21)

Country Link
US (1) US4233303A (de)
EP (1) EP0001735B1 (de)
JP (1) JPS5479296A (de)
AT (1) AT363491B (de)
AU (1) AU521585B2 (de)
CA (1) CA1109470A (de)
CS (1) CS208756B2 (de)
DD (1) DD139855A5 (de)
DE (1) DE2862017D1 (de)
DK (1) DK148260C (de)
FI (1) FI66383C (de)
HK (1) HK6385A (de)
HU (1) HU180219B (de)
IE (1) IE47884B1 (de)
IT (1) IT1109208B (de)
NO (1) NO147562C (de)
NZ (1) NZ188566A (de)
SE (1) SE416810C (de)
SG (1) SG85584G (de)
SU (1) SU755199A3 (de)
ZA (1) ZA785335B (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7810947L (sv) * 1978-10-20 1980-04-21 Draco Ab 3-alkylxanthines
SE8002910L (sv) * 1980-04-18 1981-10-19 Draco Ab 3,8-dialkylxantiner, forfarande for deras framstellning, beredning och metoder for behandling av kronisk obstruktiv luftvegssjukdom och kardiovaskulera sjukdomar
US4755517A (en) * 1986-07-31 1988-07-05 Warner-Lambert Company Derivatives of xanthine, pharmaceutical compositions and methods of use therefor
US5298508A (en) * 1988-07-19 1994-03-29 The United States Of America As Represented By The Department Of Health And Human Services Irreversible inhibitors of adenosine receptors
US5321029A (en) * 1988-11-14 1994-06-14 Beecham-Wuelfing Gmbh & Co.K.G. Xanthines
GB8826595D0 (en) * 1988-11-14 1988-12-21 Beecham Wuelfing Gmbh & Co Kg Active compounds
IT1229195B (it) * 1989-03-10 1991-07-25 Poli Ind Chimica Spa Derivati xantinici ad attivita' broncodilatatrice e loro applicazioni terapeutiche.
GB8929208D0 (en) * 1989-12-27 1990-02-28 Almirall Lab New xanthine derivatives
US5047534A (en) * 1990-03-26 1991-09-10 Merrell Dow Pharmaceuticals Inc. Selective adenosine receptor agents
US5342841A (en) * 1992-03-12 1994-08-30 Kyowa Hakko Kogyo Co., Ltd. Xanthine derivatives
US5366977A (en) * 1992-09-29 1994-11-22 The United States Of America, As Represented By The Department Of Health And Human Services Method of treating cystic fibrosis using 8-cyclopentyl-1,3-dipropylxanthine or xanthine amino congeners
US5395836A (en) * 1993-04-07 1995-03-07 Kyowa Hakko Kogyo Co., Ltd. 8-tricycloalkyl xanthine derivatives
GB9312853D0 (en) * 1993-06-22 1993-08-04 Euro Celtique Sa Chemical compounds
US5922751A (en) * 1994-06-24 1999-07-13 Euro-Celtique, S.A. Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same
US5591776A (en) * 1994-06-24 1997-01-07 Euro-Celtique, S.A. Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV
US5661153A (en) * 1994-07-19 1997-08-26 Japan Energy Corporation 1-arylpyrimidine derivatives and pharmaceutical use thereof
EP0799040B1 (de) * 1994-12-13 2003-08-20 Euroceltique S.A. Dreifachsubstituierte thioxanthine
JPH10508032A (ja) * 1994-12-13 1998-08-04 ユーロ−セルティーク，エス．エイ． アリールチオキサンチン類
US6166041A (en) * 1995-10-11 2000-12-26 Euro-Celtique, S.A. 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma
US6075016A (en) * 1996-04-10 2000-06-13 Euro-Celtique S.A. 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity
US5864037A (en) * 1996-06-06 1999-01-26 Euro-Celtique, S.A. Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity
JP2006524699A (ja) 2003-04-25 2006-11-02 ノヴァカーディア，インク． 腎機能障害を持つ個体における利尿改善法
KR20070008689A (ko) * 2004-04-16 2007-01-17 노바카르디아, 인코포레이션 아데노신 ａ１ 수용체 길항제 및 알도스테론 억제제를포함하는 병용 요법
US20070049757A1 (en) * 2005-08-26 2007-03-01 Rieger Jayson M Methods for the synthesis of substituted amino uracils

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1911279A1 (de) * 1969-03-05 1970-11-12 Eckert Dr Theodor Verfahren zur Erhoehung der Resorptionsfaehigkeit von Arzneistoffen
US3900474A (en) * 1973-05-14 1975-08-19 Kendall & Co Trifluoroalkyl, fluorobenzyl, pentafluorobenzyl, fluorobenzenesulfonyl, and pentafluorobenzenesulfonyl theophyllines
US4061753A (en) * 1976-02-06 1977-12-06 Interx Research Corporation Treating psoriasis with transient pro-drug forms of xanthine derivatives
CA1077932A (en) 1976-03-31 1980-05-20 Berlex Laboratories, Inc. Xanthine compounds and method of treating bronchospastic and allergic diseases
US4120947A (en) * 1976-03-31 1978-10-17 Cooper Laboratories, Inc. Xanthine compounds and method of treating bronchospastic and allergic diseases

Also Published As

Publication number Publication date
SE7711581L (sv) 1979-04-14
AU4036578A (en) 1980-04-17
AT363491B (de) 1981-08-10
DK453778A (da) 1979-04-15
EP0001735B1 (de) 1982-09-01
AU521585B2 (en) 1982-04-22
SE416810B (sv) 1981-02-09
IT1109208B (it) 1985-12-16
DK148260B (da) 1985-05-20
NO147562B (no) 1983-01-24
SG85584G (en) 1985-06-07
NZ188566A (en) 1984-07-06
ATA714478A (de) 1980-09-15
DE2862017D1 (en) 1982-10-28
HK6385A (en) 1985-02-01
CA1109470A (en) 1981-09-22
EP0001735A1 (de) 1979-05-02
JPS5479296A (en) 1979-06-25
NO783471L (no) 1979-04-18
IT7851499A0 (it) 1978-10-13
IE47884B1 (en) 1984-07-11
IE782041L (en) 1979-04-14
HU180219B (en) 1983-02-28
FI66383C (fi) 1984-10-10
NO147562C (no) 1983-05-18
FI66383B (fi) 1984-06-29
DK148260C (da) 1986-02-10
DD139855A5 (de) 1980-01-23
US4233303A (en) 1980-11-11
SU755199A3 (en) 1980-08-07
FI783126A (fi) 1979-04-15
CS208756B2 (en) 1981-09-15
SE416810C (sv) 1982-05-11

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