DK453778A - Fremgangsmaade til fremstilling af xantinderivater - Google Patents
Fremgangsmaade til fremstilling af xantinderivaterInfo
- Publication number
- DK453778A DK453778A DK453778A DK453778A DK453778A DK 453778 A DK453778 A DK 453778A DK 453778 A DK453778 A DK 453778A DK 453778 A DK453778 A DK 453778A DK 453778 A DK453778 A DK 453778A
- Authority
- DK
- Denmark
- Prior art keywords
- procedure
- preparation
- xantine
- derivatives
- xantine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pulmonology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE7711581 | 1977-10-14 | ||
SE7711581A SE416810C (sv) | 1977-10-14 | 1977-10-14 | Forfarande for framstellning av xantinderivat med antiallergisk aktivitet |
Publications (3)
Publication Number | Publication Date |
---|---|
DK453778A true DK453778A (da) | 1979-04-15 |
DK148260B DK148260B (da) | 1985-05-20 |
DK148260C DK148260C (da) | 1986-02-10 |
Family
ID=20332576
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK453778A DK148260C (da) | 1977-10-14 | 1978-10-12 | Analogifremgangsmaade til fremstilling af 1,3,8-trisubstituerede xantinderivater eller salte deraf |
Country Status (21)
Country | Link |
---|---|
US (1) | US4233303A (da) |
EP (1) | EP0001735B1 (da) |
JP (1) | JPS5479296A (da) |
AT (1) | AT363491B (da) |
AU (1) | AU521585B2 (da) |
CA (1) | CA1109470A (da) |
CS (1) | CS208756B2 (da) |
DD (1) | DD139855A5 (da) |
DE (1) | DE2862017D1 (da) |
DK (1) | DK148260C (da) |
FI (1) | FI66383C (da) |
HK (1) | HK6385A (da) |
HU (1) | HU180219B (da) |
IE (1) | IE47884B1 (da) |
IT (1) | IT1109208B (da) |
NO (1) | NO147562C (da) |
NZ (1) | NZ188566A (da) |
SE (1) | SE416810C (da) |
SG (1) | SG85584G (da) |
SU (1) | SU755199A3 (da) |
ZA (1) | ZA785335B (da) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE7810947L (sv) * | 1978-10-20 | 1980-04-21 | Draco Ab | 3-alkylxanthines |
SE8002910L (sv) * | 1980-04-18 | 1981-10-19 | Draco Ab | 3,8-dialkylxantiner, forfarande for deras framstellning, beredning och metoder for behandling av kronisk obstruktiv luftvegssjukdom och kardiovaskulera sjukdomar |
US4755517A (en) * | 1986-07-31 | 1988-07-05 | Warner-Lambert Company | Derivatives of xanthine, pharmaceutical compositions and methods of use therefor |
US5298508A (en) * | 1988-07-19 | 1994-03-29 | The United States Of America As Represented By The Department Of Health And Human Services | Irreversible inhibitors of adenosine receptors |
GB8826595D0 (en) * | 1988-11-14 | 1988-12-21 | Beecham Wuelfing Gmbh & Co Kg | Active compounds |
US5321029A (en) * | 1988-11-14 | 1994-06-14 | Beecham-Wuelfing Gmbh & Co.K.G. | Xanthines |
IT1229195B (it) * | 1989-03-10 | 1991-07-25 | Poli Ind Chimica Spa | Derivati xantinici ad attivita' broncodilatatrice e loro applicazioni terapeutiche. |
GB8929208D0 (en) * | 1989-12-27 | 1990-02-28 | Almirall Lab | New xanthine derivatives |
US5047534A (en) * | 1990-03-26 | 1991-09-10 | Merrell Dow Pharmaceuticals Inc. | Selective adenosine receptor agents |
US5342841A (en) * | 1992-03-12 | 1994-08-30 | Kyowa Hakko Kogyo Co., Ltd. | Xanthine derivatives |
US5366977A (en) * | 1992-09-29 | 1994-11-22 | The United States Of America, As Represented By The Department Of Health And Human Services | Method of treating cystic fibrosis using 8-cyclopentyl-1,3-dipropylxanthine or xanthine amino congeners |
US5395836A (en) * | 1993-04-07 | 1995-03-07 | Kyowa Hakko Kogyo Co., Ltd. | 8-tricycloalkyl xanthine derivatives |
GB9312853D0 (en) * | 1993-06-22 | 1993-08-04 | Euro Celtique Sa | Chemical compounds |
US5922751A (en) * | 1994-06-24 | 1999-07-13 | Euro-Celtique, S.A. | Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same |
US5591776A (en) * | 1994-06-24 | 1997-01-07 | Euro-Celtique, S.A. | Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV |
US5661153A (en) * | 1994-07-19 | 1997-08-26 | Japan Energy Corporation | 1-arylpyrimidine derivatives and pharmaceutical use thereof |
ATE247116T1 (de) * | 1994-12-13 | 2003-08-15 | Euro Celtique Sa | Arylthioxanthine |
CA2206804C (en) * | 1994-12-13 | 2002-03-19 | Euro-Celtique, S.A. | Trisubstituted thioxanthines |
US6166041A (en) * | 1995-10-11 | 2000-12-26 | Euro-Celtique, S.A. | 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma |
US6075016A (en) * | 1996-04-10 | 2000-06-13 | Euro-Celtique S.A. | 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity |
US5864037A (en) | 1996-06-06 | 1999-01-26 | Euro-Celtique, S.A. | Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity |
US7579331B2 (en) | 2003-04-25 | 2009-08-25 | Novacardia, Inc. | Method of improved diuresis in individuals with impaired renal function |
BRPI0509753A (pt) * | 2004-04-16 | 2007-10-16 | Novacardia Inc | composição farmacêutica e método de tratamento de doença cardiovascular |
US20070049757A1 (en) * | 2005-08-26 | 2007-03-01 | Rieger Jayson M | Methods for the synthesis of substituted amino uracils |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1911279A1 (de) * | 1969-03-05 | 1970-11-12 | Eckert Dr Theodor | Verfahren zur Erhoehung der Resorptionsfaehigkeit von Arzneistoffen |
US3900474A (en) * | 1973-05-14 | 1975-08-19 | Kendall & Co | Trifluoroalkyl, fluorobenzyl, pentafluorobenzyl, fluorobenzenesulfonyl, and pentafluorobenzenesulfonyl theophyllines |
US4061753A (en) * | 1976-02-06 | 1977-12-06 | Interx Research Corporation | Treating psoriasis with transient pro-drug forms of xanthine derivatives |
CA1077932A (en) | 1976-03-31 | 1980-05-20 | Berlex Laboratories, Inc. | Xanthine compounds and method of treating bronchospastic and allergic diseases |
US4120947A (en) * | 1976-03-31 | 1978-10-17 | Cooper Laboratories, Inc. | Xanthine compounds and method of treating bronchospastic and allergic diseases |
-
1977
- 1977-10-14 SE SE7711581A patent/SE416810C/sv unknown
-
1978
- 1978-09-19 ZA ZA00785335A patent/ZA785335B/xx unknown
- 1978-09-29 US US05/947,002 patent/US4233303A/en not_active Expired - Lifetime
- 1978-10-03 EP EP78850015A patent/EP0001735B1/en not_active Expired
- 1978-10-03 AU AU40365/78A patent/AU521585B2/en not_active Expired
- 1978-10-03 DE DE7878850015T patent/DE2862017D1/de not_active Expired
- 1978-10-03 NZ NZ188566A patent/NZ188566A/en unknown
- 1978-10-04 AT AT0714478A patent/AT363491B/de not_active IP Right Cessation
- 1978-10-10 CA CA313,026A patent/CA1109470A/en not_active Expired
- 1978-10-12 DD DD78208423A patent/DD139855A5/de unknown
- 1978-10-12 DK DK453778A patent/DK148260C/da not_active IP Right Cessation
- 1978-10-13 FI FI783126A patent/FI66383C/fi not_active IP Right Cessation
- 1978-10-13 NO NO783471A patent/NO147562C/no unknown
- 1978-10-13 IT IT51499/78A patent/IT1109208B/it active
- 1978-10-13 IE IE2041/78A patent/IE47884B1/en unknown
- 1978-10-13 CS CS786669A patent/CS208756B2/cs unknown
- 1978-10-13 SU SU782675299A patent/SU755199A3/ru active
- 1978-10-13 HU HU78DA359A patent/HU180219B/hu unknown
- 1978-10-14 JP JP12573978A patent/JPS5479296A/ja active Pending
-
1984
- 1984-11-29 SG SG855/84A patent/SG85584G/en unknown
-
1985
- 1985-01-24 HK HK63/85A patent/HK6385A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
DE2862017D1 (en) | 1982-10-28 |
US4233303A (en) | 1980-11-11 |
SE416810C (sv) | 1982-07-19 |
NZ188566A (en) | 1984-07-06 |
SE7711581L (sv) | 1979-04-15 |
SG85584G (en) | 1985-06-07 |
IE47884B1 (en) | 1984-07-11 |
CA1109470A (en) | 1981-09-22 |
IE782041L (en) | 1979-04-14 |
EP0001735B1 (en) | 1982-09-01 |
HK6385A (en) | 1985-02-01 |
NO147562C (no) | 1983-05-18 |
ZA785335B (en) | 1979-09-26 |
IT1109208B (it) | 1985-12-16 |
SE416810B (sv) | 1981-02-09 |
FI783126A (fi) | 1979-04-15 |
IT7851499A0 (it) | 1978-10-13 |
DK148260C (da) | 1986-02-10 |
JPS5479296A (en) | 1979-06-25 |
DD139855A5 (de) | 1980-01-23 |
NO783471L (no) | 1979-04-18 |
HU180219B (en) | 1983-02-28 |
SU755199A3 (en) | 1980-08-07 |
DK148260B (da) | 1985-05-20 |
AT363491B (de) | 1981-08-10 |
FI66383C (fi) | 1984-10-10 |
CS208756B2 (en) | 1981-09-15 |
FI66383B (fi) | 1984-06-29 |
AU521585B2 (en) | 1982-04-22 |
NO147562B (no) | 1983-01-24 |
AU4036578A (en) | 1980-04-17 |
EP0001735A1 (en) | 1979-05-02 |
ATA714478A (de) | 1980-09-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PBP | Patent lapsed |