ZA781525B - Morphine derivatives - Google Patents

Morphine derivatives

Info

Publication number
ZA781525B
ZA781525B ZA00781525A ZA781525A ZA781525B ZA 781525 B ZA781525 B ZA 781525B ZA 00781525 A ZA00781525 A ZA 00781525A ZA 781525 A ZA781525 A ZA 781525A ZA 781525 B ZA781525 B ZA 781525B
Authority
ZA
South Africa
Prior art keywords
morphine derivatives
morphine
derivatives
Prior art date
Application number
ZA00781525A
Other languages
English (en)
Inventor
R Kobylecki
I Guest
J Lewis
G Kirby
Original Assignee
Reckitt & Colmann Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reckitt & Colmann Prod Ltd filed Critical Reckitt & Colmann Prod Ltd
Publication of ZA781525B publication Critical patent/ZA781525B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D489/00Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA00781525A 1977-03-23 1978-03-15 Morphine derivatives ZA781525B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB12342/77A GB1587831A (en) 1977-03-23 1977-03-23 Morphine derivatives

Publications (1)

Publication Number Publication Date
ZA781525B true ZA781525B (en) 1979-04-25

Family

ID=10002756

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00781525A ZA781525B (en) 1977-03-23 1978-03-15 Morphine derivatives

Country Status (25)

Country Link
US (1) US4241067A (fr)
JP (1) JPS53121798A (fr)
AR (1) AR218296A1 (fr)
AT (1) AT360664B (fr)
AU (1) AU518614B2 (fr)
BE (1) BE865182A (fr)
CA (1) CA1089455A (fr)
CH (1) CH630629A5 (fr)
CS (1) CS199522B2 (fr)
DD (1) DD135081A5 (fr)
DE (1) DE2812581A1 (fr)
DK (1) DK149753C (fr)
ES (1) ES468170A1 (fr)
FR (1) FR2384775A1 (fr)
GB (1) GB1587831A (fr)
HU (1) HU177722B (fr)
IE (1) IE46442B1 (fr)
IT (1) IT1105172B (fr)
LU (1) LU79295A1 (fr)
NL (1) NL7803084A (fr)
NZ (1) NZ186693A (fr)
PL (1) PL111722B1 (fr)
SE (1) SE436132B (fr)
SU (1) SU856381A3 (fr)
ZA (1) ZA781525B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4362870A (en) * 1980-01-16 1982-12-07 Regents Of The University Of Minnesota Selective opioid receptor alkylating agents
US4401672A (en) * 1981-10-13 1983-08-30 Regents Of The University Of Minnesota Non-addictive narcotic antitussive preparation
WO1983003197A1 (fr) * 1982-03-16 1983-09-29 Univ Rockefeller Procede pour reduire la dysmotilite gastro-intestinale
GB8711558D0 (en) * 1987-05-15 1987-06-17 Reckitt & Colmann Prod Ltd Derivative of codeine
CA2105072C (fr) 1992-01-23 1998-07-28 Hiroshi Nagase Derive de la morphinane et ses applications pharmaceutiques
DE69414085T2 (de) * 1993-07-19 1999-03-18 Toray Industries, Inc., Tokio/Tokyo Wirkstoff zum schutze von gehirnzellen
JP3843456B2 (ja) * 1993-07-23 2006-11-08 東レ株式会社 モルヒナン誘導体および医薬用途
US20060063792A1 (en) * 2004-09-17 2006-03-23 Adolor Corporation Substituted morphinans and methods of their use
WO2006138020A2 (fr) 2005-06-16 2006-12-28 Mallinckrodt Inc. Trajet synthetique vers 14-hydroxyl opiates via 1-halo-thebaine ou analogues
US9969746B2 (en) 2013-12-05 2018-05-15 The University Of Bath Opioid compounds and their uses

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3332950A (en) * 1963-03-23 1967-07-25 Endo Lab 14-hydroxydihydronormorphinone derivatives
IL26896A (en) * 1966-01-19 1970-11-30 Endo Lab 14 - Hydroxynormorphinins and 14 - Hydroxynormorphinones
BE788478A (fr) * 1971-09-08 1973-03-06 Bristol Myers Co Procede de preparation de composes analgesiques
US4017497A (en) * 1975-11-18 1977-04-12 Bristol-Myers Company Process for the preparation of 14-hydroxymorphinan derivatives

Also Published As

Publication number Publication date
NL7803084A (nl) 1978-09-26
ES468170A1 (es) 1979-01-01
SE436132B (sv) 1984-11-12
IT7848545A0 (it) 1978-03-22
DK129978A (da) 1978-09-24
CS199522B2 (en) 1980-07-31
CA1089455A (fr) 1980-11-11
PL205497A1 (pl) 1979-06-04
ATA204378A (de) 1980-06-15
LU79295A1 (fr) 1979-10-29
IE46442B1 (en) 1983-06-15
US4241067A (en) 1980-12-23
NZ186693A (en) 1979-10-25
AR218296A1 (es) 1980-05-30
IE780514L (en) 1978-09-23
HU177722B (en) 1981-12-28
DD135081A5 (de) 1979-04-11
JPS6259112B2 (fr) 1987-12-09
CH630629A5 (fr) 1982-06-30
IT1105172B (it) 1985-10-28
DE2812581A1 (de) 1978-09-28
FR2384775B1 (fr) 1981-04-30
GB1587831A (en) 1981-04-08
FR2384775A1 (fr) 1978-10-20
AU518614B2 (en) 1981-10-08
SU856381A3 (ru) 1981-08-15
DK149753C (da) 1987-07-06
AT360664B (de) 1981-01-26
SE7803329L (sv) 1978-09-24
DK149753B (da) 1986-09-22
JPS53121798A (en) 1978-10-24
BE865182A (fr) 1978-09-22
AU3435678A (en) 1979-09-27
PL111722B1 (en) 1980-09-30

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