ZA777398B - New piperazine derivatives and a process for the preparation thereof - Google Patents

New piperazine derivatives and a process for the preparation thereof

Info

Publication number
ZA777398B
ZA777398B ZA00777398A ZA777398A ZA777398B ZA 777398 B ZA777398 B ZA 777398B ZA 00777398 A ZA00777398 A ZA 00777398A ZA 777398 A ZA777398 A ZA 777398A ZA 777398 B ZA777398 B ZA 777398B
Authority
ZA
South Africa
Prior art keywords
preparation
piperazine derivatives
new piperazine
new
derivatives
Prior art date
Application number
ZA00777398A
Other languages
English (en)
Inventor
J Czombos
M Bartok
L Szporny
E Karpati
A Molnar
F Noteisz
K Felfoeldi
J Apjok
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of ZA777398B publication Critical patent/ZA777398B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78Ring systems having three or more relevant rings
    • C07D311/80Dibenzopyrans; Hydrogenated dibenzopyrans
    • C07D311/82Xanthenes
    • C07D311/84Xanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Anesthesiology (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA00777398A 1976-12-15 1977-12-12 New piperazine derivatives and a process for the preparation thereof ZA777398B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU76RI605A HU174215B (hu) 1976-12-15 1976-12-15 Sposob poluchenija novykh proizvodnykh piperazina i kislotnykh additivnykh i chetvjortichnykh solej

Publications (1)

Publication Number Publication Date
ZA777398B true ZA777398B (en) 1978-10-25

Family

ID=11001009

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00777398A ZA777398B (en) 1976-12-15 1977-12-12 New piperazine derivatives and a process for the preparation thereof

Country Status (21)

Country Link
US (2) US4140790A (de)
JP (2) JPS6026114B2 (de)
AT (1) AT359507B (de)
BE (1) BE861849A (de)
CA (1) CA1080219A (de)
CH (1) CH632750A5 (de)
DE (1) DE2755707A1 (de)
ES (1) ES465061A1 (de)
FI (1) FI65427C (de)
FR (1) FR2374322A1 (de)
GB (1) GB1580227A (de)
HU (1) HU174215B (de)
IL (1) IL53552A (de)
IN (1) IN146474B (de)
NL (1) NL7713827A (de)
NO (1) NO147306C (de)
PT (1) PT67403B (de)
SE (1) SE430159B (de)
SU (1) SU694071A3 (de)
YU (1) YU293677A (de)
ZA (1) ZA777398B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU174215B (hu) * 1976-12-15 1979-11-28 Richter Gedeon Vegyeszet Sposob poluchenija novykh proizvodnykh piperazina i kislotnykh additivnykh i chetvjortichnykh solej
US4703120A (en) * 1986-04-28 1987-10-27 Ortho Pharmaceutical Corporation Furo(3,4-d)pyrimidine-2,4-dione derivatives and intermediates thereof
CN1060168C (zh) * 1994-05-06 2001-01-03 中国人民解放军军事医学科学院毒物药物研究所 新的呫吨衍生物,其制备方法及含它们的药物组合物
PL371486A1 (en) 2002-02-01 2005-06-13 Astrazeneca Ab Quinazoline compounds
CA2521330A1 (en) * 2003-04-08 2004-10-21 Neuromed Technologies, Inc. Calcium channel inhibitors comprising benzhydril spaced from piperazine
US20080207738A1 (en) * 2007-02-28 2008-08-28 Cancure Laboratories, Llc Drug combinations to treat drug resistant tumors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3481930A (en) * 1966-11-21 1969-12-02 American Home Prod Xanthene and thioxanthene-9 ureas and propionamides
US3502662A (en) * 1968-03-18 1970-03-24 American Home Prod N-(9-xanthenyl or thioxanthenyl)-3-amino or iodo-propionamides and 4-(9-xanthenyl or thioxanthenyl)-thiosemicarbazones
FR2201084B1 (de) * 1972-09-29 1975-10-31 Bouchara Emile
US3953449A (en) * 1973-05-09 1976-04-27 Synthelabo 2-(4-M-CF3 or -SCF3 phenylpiperazino)-ethyl benzoates
HU174215B (hu) * 1976-12-15 1979-11-28 Richter Gedeon Vegyeszet Sposob poluchenija novykh proizvodnykh piperazina i kislotnykh additivnykh i chetvjortichnykh solej

Also Published As

Publication number Publication date
DE2755707A1 (de) 1978-06-29
NO774294L (no) 1978-06-16
BE861849A (fr) 1978-03-31
IL53552A (en) 1981-07-31
SE430159B (sv) 1983-10-24
JPS5377073A (en) 1978-07-08
PT67403A (en) 1978-01-01
NL7713827A (nl) 1978-06-19
FR2374322A1 (fr) 1978-07-13
NO147306C (no) 1983-03-16
YU293677A (en) 1982-08-31
GB1580227A (en) 1980-11-26
PT67403B (en) 1979-05-21
AT359507B (de) 1980-11-10
SE7713906L (sv) 1978-06-16
IN146474B (de) 1979-06-16
FI773743A (fi) 1978-06-16
ATA867677A (de) 1980-04-15
FI65427B (fi) 1984-01-31
US4140790A (en) 1979-02-20
IL53552A0 (en) 1978-03-10
CH632750A5 (de) 1982-10-29
ES465061A1 (es) 1979-01-01
JPS6026114B2 (ja) 1985-06-21
US4250310A (en) 1981-02-10
HU174215B (hu) 1979-11-28
NO147306B (no) 1982-12-06
JPS5377080A (en) 1978-07-08
FI65427C (fi) 1984-05-10
SU694071A3 (ru) 1979-10-25
FR2374322B1 (de) 1981-11-27
CA1080219A (en) 1980-06-24

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