JPS5377073A - Piperadine derivative compound and its production and medical drugs containing said compound - Google Patents

Piperadine derivative compound and its production and medical drugs containing said compound

Info

Publication number
JPS5377073A
JPS5377073A JP14945477A JP14945477A JPS5377073A JP S5377073 A JPS5377073 A JP S5377073A JP 14945477 A JP14945477 A JP 14945477A JP 14945477 A JP14945477 A JP 14945477A JP S5377073 A JPS5377073 A JP S5377073A
Authority
JP
Japan
Prior art keywords
compound
production
drugs containing
medical drugs
piperadine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP14945477A
Other languages
English (en)
Inventor
Fuerufuerudei Kaarorii
Apuyoku Yoozefu
Barutooku Mihaarii
Tsuomubosu Yoozefu
Morunaaru Aarupaado
Noteisu Fuerentsu
Kaarupaachi Egon
Suporunii Raasuroo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of JPS5377073A publication Critical patent/JPS5377073A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • C07D311/82—Xanthenes
    • C07D311/84—Xanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
JP14945477A 1976-12-15 1977-12-14 Piperadine derivative compound and its production and medical drugs containing said compound Pending JPS5377073A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU76RI605A HU174215B (hu) 1976-12-15 1976-12-15 Sposob poluchenija novykh proizvodnykh piperazina i kislotnykh additivnykh i chetvjortichnykh solej

Publications (1)

Publication Number Publication Date
JPS5377073A true JPS5377073A (en) 1978-07-08

Family

ID=11001009

Family Applications (2)

Application Number Title Priority Date Filing Date
JP52140843A Expired JPS6026114B2 (ja) 1974-06-25 1977-11-25 ベンゾジアゼピン誘導体の製造方法
JP14945477A Pending JPS5377073A (en) 1976-12-15 1977-12-14 Piperadine derivative compound and its production and medical drugs containing said compound

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP52140843A Expired JPS6026114B2 (ja) 1974-06-25 1977-11-25 ベンゾジアゼピン誘導体の製造方法

Country Status (21)

Country Link
US (2) US4140790A (ja)
JP (2) JPS6026114B2 (ja)
AT (1) AT359507B (ja)
BE (1) BE861849A (ja)
CA (1) CA1080219A (ja)
CH (1) CH632750A5 (ja)
DE (1) DE2755707A1 (ja)
ES (1) ES465061A1 (ja)
FI (1) FI65427C (ja)
FR (1) FR2374322A1 (ja)
GB (1) GB1580227A (ja)
HU (1) HU174215B (ja)
IL (1) IL53552A (ja)
IN (1) IN146474B (ja)
NL (1) NL7713827A (ja)
NO (1) NO147306C (ja)
PT (1) PT67403B (ja)
SE (1) SE430159B (ja)
SU (1) SU694071A3 (ja)
YU (1) YU293677A (ja)
ZA (1) ZA777398B (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006522742A (ja) * 2003-04-08 2006-10-05 ニューロームド テクノロジーズ、インク． ピペラジンから距離をおいて配置したベンズヒドリル基から成る一群のカルシウムチャンネル阻害剤

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU174215B (hu) * 1976-12-15 1979-11-28 Richter Gedeon Vegyeszet Sposob poluchenija novykh proizvodnykh piperazina i kislotnykh additivnykh i chetvjortichnykh solej
US4703120A (en) * 1986-04-28 1987-10-27 Ortho Pharmaceutical Corporation Furo(3,4-d)pyrimidine-2,4-dione derivatives and intermediates thereof
CN1060168C (zh) * 1994-05-06 2001-01-03 中国人民解放军军事医学科学院毒物药物研究所 新的呫吨衍生物，其制备方法及含它们的药物组合物
CA2473572C (en) 2002-02-01 2011-05-10 Astrazeneca Ab Quinazoline compounds
US20080207738A1 (en) * 2007-02-28 2008-08-28 Cancure Laboratories, Llc Drug combinations to treat drug resistant tumors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3481930A (en) * 1966-11-21 1969-12-02 American Home Prod Xanthene and thioxanthene-9 ureas and propionamides
US3502662A (en) * 1968-03-18 1970-03-24 American Home Prod N-(9-xanthenyl or thioxanthenyl)-3-amino or iodo-propionamides and 4-(9-xanthenyl or thioxanthenyl)-thiosemicarbazones
FR2201084B1 (ja) * 1972-09-29 1975-10-31 Bouchara Emile
GB1437868A (en) * 1973-05-09 1976-06-03 Synthelabo Arylpiperazinoalkyl esters
HU174215B (hu) * 1976-12-15 1979-11-28 Richter Gedeon Vegyeszet Sposob poluchenija novykh proizvodnykh piperazina i kislotnykh additivnykh i chetvjortichnykh solej

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006522742A (ja) * 2003-04-08 2006-10-05 ニューロームド テクノロジーズ、インク． ピペラジンから距離をおいて配置したベンズヒドリル基から成る一群のカルシウムチャンネル阻害剤

Also Published As

Publication number Publication date
ATA867677A (de) 1980-04-15
JPS5377080A (en) 1978-07-08
CA1080219A (en) 1980-06-24
BE861849A (fr) 1978-03-31
SU694071A3 (ru) 1979-10-25
PT67403A (en) 1978-01-01
FI65427C (fi) 1984-05-10
SE7713906L (sv) 1978-06-16
FI65427B (fi) 1984-01-31
US4250310A (en) 1981-02-10
FR2374322B1 (ja) 1981-11-27
IN146474B (ja) 1979-06-16
NO147306C (no) 1983-03-16
NL7713827A (nl) 1978-06-19
YU293677A (en) 1982-08-31
ES465061A1 (es) 1979-01-01
GB1580227A (en) 1980-11-26
HU174215B (hu) 1979-11-28
US4140790A (en) 1979-02-20
JPS6026114B2 (ja) 1985-06-21
CH632750A5 (de) 1982-10-29
DE2755707A1 (de) 1978-06-29
PT67403B (en) 1979-05-21
NO147306B (no) 1982-12-06
NO774294L (no) 1978-06-16
SE430159B (sv) 1983-10-24
AT359507B (de) 1980-11-10
IL53552A0 (en) 1978-03-10
ZA777398B (en) 1978-10-25
FR2374322A1 (fr) 1978-07-13
FI773743A (fi) 1978-06-16
IL53552A (en) 1981-07-31

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