ZA764305B - Phenoxy derivatives process for their preparation and pharmaceutical compositions containing them - Google Patents
Phenoxy derivatives process for their preparation and pharmaceutical compositions containing themInfo
- Publication number
- ZA764305B ZA764305B ZA764305A ZA764305A ZA764305B ZA 764305 B ZA764305 B ZA 764305B ZA 764305 A ZA764305 A ZA 764305A ZA 764305 A ZA764305 A ZA 764305A ZA 764305 B ZA764305 B ZA 764305B
- Authority
- ZA
- South Africa
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- phenoxy derivatives
- derivatives process
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Diabetes (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB30392/75A GB1489711A (en) | 1975-07-21 | 1975-07-21 | 1-phenoxyphenyl-piperazine derivatives process for their preparation and pharmaceutical compositions containing the |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA764305B true ZA764305B (en) | 1977-07-27 |
Family
ID=10306953
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA764305A ZA764305B (en) | 1975-07-21 | 1976-07-20 | Phenoxy derivatives process for their preparation and pharmaceutical compositions containing them |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4064245A (es) |
| JP (1) | JPS5225783A (es) |
| AR (1) | AR211273A1 (es) |
| AT (1) | AT350576B (es) |
| AU (1) | AU498329B2 (es) |
| BE (1) | BE844343A (es) |
| CA (1) | CA1085400A (es) |
| CH (1) | CH595368A5 (es) |
| DE (1) | DE2631885C2 (es) |
| ES (1) | ES450012A1 (es) |
| FR (1) | FR2318634A1 (es) |
| GB (1) | GB1489711A (es) |
| GR (1) | GR61593B (es) |
| IE (1) | IE43258B1 (es) |
| MX (1) | MX3413E (es) |
| NL (1) | NL162075C (es) |
| OA (1) | OA05385A (es) |
| PH (1) | PH12743A (es) |
| PT (1) | PT65380B (es) |
| YU (1) | YU163075A (es) |
| ZA (1) | ZA764305B (es) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4210646A (en) * | 1978-04-11 | 1980-07-01 | Janssen Pharmaceutica N.V. | Antimicrobial compositions containing 1-(aryloxyphenyl)piperazines |
| DE3235589A1 (de) * | 1982-09-25 | 1984-03-29 | Hoechst Ag, 6230 Frankfurt | Benzylether von phenol-mannich-basen, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen, zwischenprodukte und verfahren zu deren herstellung |
| JPS63174868U (es) * | 1987-04-14 | 1988-11-14 | ||
| UA81749C2 (uk) * | 2001-10-04 | 2008-02-11 | Х. Луннбек А/С | Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну |
| WO2007078335A2 (en) * | 2005-12-21 | 2007-07-12 | Decode Genetics, Ehf. | Biaryl nitrogen heterocycle inhibitors of lta4h for treating inflammation |
| TW200932233A (en) * | 2007-11-13 | 2009-08-01 | Lundbeck & Co As H | Therapeutic uses of compounds having combined SERT, 5-HT3 and 5-HT1a activity |
| EP3337564A4 (en) | 2015-08-21 | 2019-01-23 | Portola Pharmaceuticals, Inc. | COMPOSITION AND METHOD FOR THE USE OF TETRAHYDROISOCHINOLINE SMALL MOLECULES FOR THE BINDING AND MODULATION OF PCSK9 PROTEIN ACTIVITY |
| US10568882B2 (en) | 2015-08-21 | 2020-02-25 | Srx Cardio, Llc | Phenylpiperazine proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators and their use |
| EP3337497B1 (en) | 2015-08-21 | 2023-07-12 | SRX Cardio, LLC | Composition and methods of use of novel phenylalanine small organic compounds to directly modulate pcsk9 protein activity |
| WO2017147328A1 (en) | 2016-02-23 | 2017-08-31 | Portola Pharmaceuticals, Inc. | Compounds for binding proprotein convertase subtilisin/kexin type 9 (pcsk9) |
| IL315313A (en) * | 2018-08-24 | 2024-10-01 | Xeniopro GmbH | Aromatic molecules for use in the treatment of pathological conditions |
| US12115154B2 (en) | 2020-12-16 | 2024-10-15 | Srx Cardio, Llc | Compounds for the modulation of proprotein convertase subtilisin/kexin type 9 (PCSK9) |
-
1975
- 1975-07-02 YU YU01630/75A patent/YU163075A/xx unknown
- 1975-07-21 GB GB30392/75A patent/GB1489711A/en not_active Expired
-
1976
- 1976-07-07 IE IE1495/76A patent/IE43258B1/en unknown
- 1976-07-08 OA OA55883A patent/OA05385A/xx unknown
- 1976-07-12 CH CH892376A patent/CH595368A5/xx not_active IP Right Cessation
- 1976-07-14 CA CA256,967A patent/CA1085400A/fr not_active Expired
- 1976-07-14 US US05/705,330 patent/US4064245A/en not_active Expired - Lifetime
- 1976-07-15 DE DE2631885A patent/DE2631885C2/de not_active Expired
- 1976-07-16 FR FR7621727A patent/FR2318634A1/fr active Granted
- 1976-07-19 GR GR51295A patent/GR61593B/el unknown
- 1976-07-19 PT PT65380A patent/PT65380B/pt unknown
- 1976-07-20 AU AU16039/76A patent/AU498329B2/en not_active Expired
- 1976-07-20 AT AT534376A patent/AT350576B/de active
- 1976-07-20 PH PH18710A patent/PH12743A/en unknown
- 1976-07-20 ZA ZA764305A patent/ZA764305B/xx unknown
- 1976-07-20 BE BE169088A patent/BE844343A/xx unknown
- 1976-07-20 AR AR263999A patent/AR211273A1/es active
- 1976-07-20 JP JP51086491A patent/JPS5225783A/ja active Granted
- 1976-07-20 NL NL7608007.A patent/NL162075C/xx not_active IP Right Cessation
- 1976-07-21 MX MX001788U patent/MX3413E/es unknown
- 1976-07-21 ES ES450012A patent/ES450012A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NL162075C (nl) | 1980-04-15 |
| PH12743A (en) | 1979-08-09 |
| JPS558504B2 (es) | 1980-03-04 |
| FR2318634A1 (fr) | 1977-02-18 |
| GB1489711A (en) | 1977-10-26 |
| IE43258B1 (en) | 1981-01-14 |
| JPS5225783A (en) | 1977-02-25 |
| ATA534376A (de) | 1978-11-15 |
| CA1085400A (fr) | 1980-09-09 |
| FR2318634B1 (es) | 1979-06-29 |
| DE2631885A1 (de) | 1977-02-10 |
| NL7608007A (nl) | 1977-01-25 |
| MX3413E (es) | 1980-11-07 |
| OA05385A (fr) | 1981-02-28 |
| NL162075B (nl) | 1979-11-15 |
| AT350576B (de) | 1978-06-15 |
| AR211273A1 (es) | 1977-11-15 |
| AU1603976A (en) | 1978-01-26 |
| CH595368A5 (es) | 1978-02-15 |
| US4064245A (en) | 1977-12-20 |
| IE43258L (en) | 1977-01-21 |
| PT65380B (fr) | 1978-01-19 |
| AU498329B2 (en) | 1979-03-01 |
| ES450012A1 (es) | 1977-07-16 |
| BE844343A (fr) | 1977-01-20 |
| GR61593B (en) | 1978-12-02 |
| PT65380A (fr) | 1976-08-01 |
| YU163075A (en) | 1982-05-31 |
| DE2631885C2 (de) | 1982-07-15 |
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