BE844343A - Nouveaux derives phenoxy,leur procede de preparation et leur application en therapeutique - Google Patents

Nouveaux derives phenoxy,leur procede de preparation et leur application en therapeutique

Info

Publication number
BE844343A
BE844343A BE169088A BE169088A BE844343A BE 844343 A BE844343 A BE 844343A BE 169088 A BE169088 A BE 169088A BE 169088 A BE169088 A BE 169088A BE 844343 A BE844343 A BE 844343A
Authority
BE
Belgium
Prior art keywords
therapeutics
application
preparation process
phenoxy derivatives
new phenoxy
Prior art date
Application number
BE169088A
Other languages
English (en)
French (fr)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of BE844343A publication Critical patent/BE844343A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BE169088A 1975-07-21 1976-07-20 Nouveaux derives phenoxy,leur procede de preparation et leur application en therapeutique BE844343A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB30392/75A GB1489711A (en) 1975-07-21 1975-07-21 1-phenoxyphenyl-piperazine derivatives process for their preparation and pharmaceutical compositions containing the

Publications (1)

Publication Number Publication Date
BE844343A true BE844343A (fr) 1977-01-20

Family

ID=10306953

Family Applications (1)

Application Number Title Priority Date Filing Date
BE169088A BE844343A (fr) 1975-07-21 1976-07-20 Nouveaux derives phenoxy,leur procede de preparation et leur application en therapeutique

Country Status (21)

Country Link
US (1) US4064245A (es)
JP (1) JPS5225783A (es)
AR (1) AR211273A1 (es)
AT (1) AT350576B (es)
AU (1) AU498329B2 (es)
BE (1) BE844343A (es)
CA (1) CA1085400A (es)
CH (1) CH595368A5 (es)
DE (1) DE2631885C2 (es)
ES (1) ES450012A1 (es)
FR (1) FR2318634A1 (es)
GB (1) GB1489711A (es)
GR (1) GR61593B (es)
IE (1) IE43258B1 (es)
MX (1) MX3413E (es)
NL (1) NL162075C (es)
OA (1) OA05385A (es)
PH (1) PH12743A (es)
PT (1) PT65380B (es)
YU (1) YU163075A (es)
ZA (1) ZA764305B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4210646A (en) * 1978-04-11 1980-07-01 Janssen Pharmaceutica N.V. Antimicrobial compositions containing 1-(aryloxyphenyl)piperazines
DE3235589A1 (de) * 1982-09-25 1984-03-29 Hoechst Ag, 6230 Frankfurt Benzylether von phenol-mannich-basen, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen, zwischenprodukte und verfahren zu deren herstellung
JPS63174868U (es) * 1987-04-14 1988-11-14
UA81749C2 (uk) 2001-10-04 2008-02-11 Х. Луннбек А/С Фенілпіперазинові похідні як інгібітори зворотного захоплення серотоніну
EP1968961A2 (en) 2005-12-21 2008-09-17 Decode Genetics EHF Biaryl nitrogen heterocycle inhibitors of lta4h for treating inflammation
TW200932233A (en) * 2007-11-13 2009-08-01 Lundbeck & Co As H Therapeutic uses of compounds having combined SERT, 5-HT3 and 5-HT1a activity
US10821106B2 (en) 2015-08-21 2020-11-03 Srx Cardio, Llc Composition and methods of use of novel phenylalanine small organic compounds to directly modulate PCSK9 protein activity
US10865185B2 (en) 2015-08-21 2020-12-15 Srx Cardio, Llc Composition and methods of use of tetrahydroisoquinoline small molecules to bind and modulate PCSK9 protein activity
EP3337788A4 (en) 2015-08-21 2019-03-27 Portola Pharmaceuticals, Inc. PHENYLPIPERAZINE PROPROTEIN CONVERTASE SUBTILISIN / -KEXIN TYPE 9 P (CSK9) MODULATORS AND THEIR USE
US20190119236A1 (en) 2016-02-23 2019-04-25 Portola Pharmaceuticals, Inc. Compounds for binding proprotein convertase subtilisin/kexin type 9 (pcsk9)
AU2019326767A1 (en) * 2018-08-24 2021-02-18 Xeniopro GmbH Aromatic molecules for use in the treatment of pathological conditions

Also Published As

Publication number Publication date
IE43258B1 (en) 1981-01-14
CA1085400A (fr) 1980-09-09
ATA534376A (de) 1978-11-15
IE43258L (en) 1977-01-21
FR2318634B1 (es) 1979-06-29
YU163075A (en) 1982-05-31
FR2318634A1 (fr) 1977-02-18
AR211273A1 (es) 1977-11-15
GR61593B (en) 1978-12-02
DE2631885C2 (de) 1982-07-15
ES450012A1 (es) 1977-07-16
NL162075C (nl) 1980-04-15
JPS558504B2 (es) 1980-03-04
AU1603976A (en) 1978-01-26
NL7608007A (nl) 1977-01-25
AT350576B (de) 1978-06-15
DE2631885A1 (de) 1977-02-10
CH595368A5 (es) 1978-02-15
ZA764305B (en) 1977-07-27
PT65380A (fr) 1976-08-01
AU498329B2 (en) 1979-03-01
OA05385A (fr) 1981-02-28
PT65380B (fr) 1978-01-19
PH12743A (en) 1979-08-09
NL162075B (nl) 1979-11-15
US4064245A (en) 1977-12-20
MX3413E (es) 1980-11-07
JPS5225783A (en) 1977-02-25
GB1489711A (en) 1977-10-26

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