ZA201706384B - Chimeric antigen receptors targeting b-cell maturation antigen - Google Patents

Chimeric antigen receptors targeting b-cell maturation antigen

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Publication number
ZA201706384B
ZA201706384B ZA2017/06384A ZA201706384A ZA201706384B ZA 201706384 B ZA201706384 B ZA 201706384B ZA 2017/06384 A ZA2017/06384 A ZA 2017/06384A ZA 201706384 A ZA201706384 A ZA 201706384A ZA 201706384 B ZA201706384 B ZA 201706384B
Authority
ZA
South Africa
Prior art keywords
cars
cell maturation
antigen
immune cells
engineered immune
Prior art date
Application number
ZA2017/06384A
Other languages
English (en)
Inventor
Tracy Chia-Chien Kuo
Riggers Javier Fernando Chaparro
Barbra Johnson Sasu
Roman Galetto
Bijan Andre Boldajipour
Cesar Adolfo Sommer
Blarcom Thomas John Van
Thomas Charles Pertel
Arvind Rajpal
Philippe Duchateau
Alexandre Juillerat
Julien Valton
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA201706384B publication Critical patent/ZA201706384B/en

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    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
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ZA2017/06384A 2015-04-13 2017-09-21 Chimeric antigen receptors targeting b-cell maturation antigen ZA201706384B (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562146825P 2015-04-13 2015-04-13
US201662286473P 2016-01-25 2016-01-25
US201662301177P 2016-02-29 2016-02-29
PCT/IB2016/051808 WO2016166630A1 (en) 2015-04-13 2016-03-30 Chimeric antigen receptors targeting b-cell maturation antigen

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SG10201806573TA (en) * 2012-05-25 2018-09-27 Cellectis Methods for engineering allogeneic and immunosuppressive resistant t cell for immunotherapy
EP3131927B8 (en) 2014-04-14 2020-12-23 Cellectis Bcma (cd269) specific chimeric antigen receptors for cancer immunotherapy
AU2015292744C1 (en) 2014-07-21 2021-01-21 Novartis Ag Treatment of cancer using humanized anti-BCMA chimeric antigen receptor
US11697825B2 (en) 2014-12-12 2023-07-11 Voyager Therapeutics, Inc. Compositions and methods for the production of scAAV
EP3250602A1 (en) 2015-01-26 2017-12-06 Cellectis T cell receptor knock out engineered immune cells, endowed with chimeric antigen receptors binding to cd123 for the treatment of relapsed/refractory acute myeloid lymphoma or blastic plasmacytoid dendritic cell neoplasm
HUE057285T2 (hu) 2015-04-13 2022-04-28 Pfizer Terápiás ellenanyagok és alkalmazásaik
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