ZA201504565B - Polymyxins, compositions, methods of making and methods of use - Google Patents

Polymyxins, compositions, methods of making and methods of use

Info

Publication number
ZA201504565B
ZA201504565B ZA2015/04565A ZA201504565A ZA201504565B ZA 201504565 B ZA201504565 B ZA 201504565B ZA 2015/04565 A ZA2015/04565 A ZA 2015/04565A ZA 201504565 A ZA201504565 A ZA 201504565A ZA 201504565 B ZA201504565 B ZA 201504565B
Authority
ZA
South Africa
Prior art keywords
methods
polymyxins
compositions
making
Prior art date
Application number
ZA2015/04565A
Other languages
English (en)
Inventor
Månsson Martin
Melander Claes
Koch Torben
Bjørnstad Vidar
Gunnes Sølvi
Original Assignee
Xellia Pharmaceuticals Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xellia Pharmaceuticals Aps filed Critical Xellia Pharmaceuticals Aps
Publication of ZA201504565B publication Critical patent/ZA201504565B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/60Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation occurring through the 4-amino group of 2,4-diamino-butanoic acid
    • C07K7/62Polymyxins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
ZA2015/04565A 2013-01-11 2015-06-24 Polymyxins, compositions, methods of making and methods of use ZA201504565B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361751341P 2013-01-11 2013-01-11
US201361904793P 2013-11-15 2013-11-15
PCT/EP2014/050320 WO2014108469A1 (en) 2013-01-11 2014-01-09 Polymyxins, compositions, methods of making and methods of use

Publications (1)

Publication Number Publication Date
ZA201504565B true ZA201504565B (en) 2016-11-30

Family

ID=50101865

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2015/04565A ZA201504565B (en) 2013-01-11 2015-06-24 Polymyxins, compositions, methods of making and methods of use

Country Status (20)

Country Link
US (1) US10640536B2 (OSRAM)
EP (1) EP2943503B1 (OSRAM)
JP (1) JP6316846B2 (OSRAM)
KR (1) KR20150107793A (OSRAM)
CN (1) CN104918951B (OSRAM)
AU (1) AU2014204873B2 (OSRAM)
BR (1) BR112015016548A2 (OSRAM)
CA (1) CA2895910C (OSRAM)
EA (1) EA027067B1 (OSRAM)
ES (1) ES2641017T3 (OSRAM)
HU (1) HUE034562T2 (OSRAM)
IL (1) IL239840A (OSRAM)
MX (1) MX360905B (OSRAM)
PT (1) PT2943503T (OSRAM)
RU (1) RU2015132569A (OSRAM)
SI (1) SI2943503T1 (OSRAM)
TW (1) TWI613219B (OSRAM)
UA (1) UA117673C2 (OSRAM)
WO (1) WO2014108469A1 (OSRAM)
ZA (1) ZA201504565B (OSRAM)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10640536B2 (en) 2013-01-11 2020-05-05 Xellia Pharmaceuticals Aps Polymyxins, compositions, methods of making and methods of use
TW201522364A (zh) * 2013-06-07 2015-06-16 Xellia Pharmaceuticals Aps 黏菌素甲磺酸鈉(cms)之定性方法
BR112017000228A2 (pt) * 2014-07-09 2017-10-31 Xellia Pharmaceuticals Aps polimixinas de baixa substituição e suas composições.
EP3718571A1 (en) 2014-10-03 2020-10-07 Xellia Pharmaceuticals ApS Compositions
TR201906108T4 (tr) 2014-10-03 2019-05-21 Xellia Pharmaceuticals Aps İnhalasyon cihazı.
US9771394B2 (en) 2014-12-16 2017-09-26 Micurx Pharmaceuticals, Inc. Antimicrobial polymyxins for treatment of bacterial infections
FI126143B (en) * 2015-01-15 2016-07-15 Northern Antibiotics Oy Polymyxine derivative and its uses
CA3000032A1 (en) * 2015-09-29 2017-04-06 Monash University Antimicrobial polymyxin derivative compounds
CN109996806B (zh) * 2016-12-09 2021-11-02 正大天晴药业集团股份有限公司 高效价的多黏菌素e2甲磺酸钠
US20230141981A1 (en) 2020-01-21 2023-05-11 Shanghai Micurx Pharmaceuticals Co., Ltd Novel compounds and composition for targeted therapy of kidney-associated cancers

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1062895A (en) 1962-12-13 1967-03-22 Wellcome Found Sulphomethyl derivatives of polymxin
DE1906699A1 (de) 1968-02-12 1970-02-05 Pfizer Neue Polymyxinderivate und Verfahren zu deren Herstellung
FR1586834A (OSRAM) * 1968-02-12 1970-03-06
JPH02504003A (ja) * 1988-04-07 1990-11-22 シャンブロム,エドワード 非トロンボゲン形成性脈管内タイムリリースカテーテル
JP2001505557A (ja) 1996-11-15 2001-04-24 パソジェネシス コーポレイション 肺感染を処置するための、純粋な生物学的活性コリスチン、その成分、およびコリスチン処方物
US5767068A (en) 1997-02-13 1998-06-16 Pathogenesis Corporation Pure biologically active colistin, its components and a colistin formulation for treatment of pulmonary infections
EP1320355B1 (en) 2001-05-18 2006-04-05 Chiron Corporation System for delivering a tobramycin formulation
US20040022740A1 (en) 2001-07-10 2004-02-05 Baker William R. Macrolide formulations for inhalation and methods of treatment of endobronchial infections
JP2009513623A (ja) * 2005-10-28 2009-04-02 アーチ ファーマラブズ リミテッド 塩酸ジェムシタビンの改良された製造方法
WO2008025560A1 (en) 2006-09-01 2008-03-06 Pari Pharma Gmbh Methods for taste masking of nebulised compositions for nasal and pulmonary inhalation therapy
US20080066739A1 (en) 2006-09-20 2008-03-20 Lemahieu Edward Methods and systems of delivering medication via inhalation
WO2012168820A1 (en) 2011-06-08 2012-12-13 Pfizer Inc. Polymyxin derivatives useful as antibacterial agents
US10640536B2 (en) 2013-01-11 2020-05-05 Xellia Pharmaceuticals Aps Polymyxins, compositions, methods of making and methods of use
TW201522364A (zh) 2013-06-07 2015-06-16 Xellia Pharmaceuticals Aps 黏菌素甲磺酸鈉(cms)之定性方法
BR112017000228A2 (pt) 2014-07-09 2017-10-31 Xellia Pharmaceuticals Aps polimixinas de baixa substituição e suas composições.
EP3718571A1 (en) 2014-10-03 2020-10-07 Xellia Pharmaceuticals ApS Compositions

Also Published As

Publication number Publication date
AU2014204873B2 (en) 2017-07-06
BR112015016548A2 (pt) 2017-07-11
TWI613219B (zh) 2018-02-01
EP2943503A1 (en) 2015-11-18
EP2943503B1 (en) 2017-08-23
PT2943503T (pt) 2017-09-28
US20160002296A1 (en) 2016-01-07
AU2014204873A1 (en) 2015-07-09
EA027067B1 (ru) 2017-06-30
HUE034562T2 (en) 2018-03-28
TW201429995A (zh) 2014-08-01
UA117673C2 (uk) 2018-09-10
IL239840A (en) 2017-09-28
MX360905B (es) 2018-11-21
CN104918951A (zh) 2015-09-16
RU2015132569A (ru) 2017-02-14
ES2641017T3 (es) 2017-11-07
IL239840A0 (en) 2015-08-31
KR20150107793A (ko) 2015-09-23
SI2943503T1 (sl) 2017-11-30
JP2016505007A (ja) 2016-02-18
CA2895910C (en) 2021-12-21
EA201591280A1 (ru) 2015-12-30
JP6316846B2 (ja) 2018-04-25
WO2014108469A1 (en) 2014-07-17
US10640536B2 (en) 2020-05-05
CN104918951B (zh) 2018-03-30
CA2895910A1 (en) 2014-07-17
MX2015008878A (es) 2015-10-30

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