ZA201407759B - Pyrrolobenzodiazepines - Google Patents

Pyrrolobenzodiazepines

Info

Publication number
ZA201407759B
ZA201407759B ZA2014/07759A ZA201407759A ZA201407759B ZA 201407759 B ZA201407759 B ZA 201407759B ZA 2014/07759 A ZA2014/07759 A ZA 2014/07759A ZA 201407759 A ZA201407759 A ZA 201407759A ZA 201407759 B ZA201407759 B ZA 201407759B
Authority
ZA
South Africa
Prior art keywords
pyrrolobenzodiazepines
Prior art date
Application number
ZA2014/07759A
Other languages
English (en)
Inventor
Khondaker Mirazur Rahman
David Thurston
Philip Wilson Howard
Original Assignee
Ucl Business Plc
Spirogen Sàrl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucl Business Plc, Spirogen Sàrl filed Critical Ucl Business Plc
Publication of ZA201407759B publication Critical patent/ZA201407759B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA2014/07759A 2012-04-30 2014-10-24 Pyrrolobenzodiazepines ZA201407759B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261640310P 2012-04-30 2012-04-30
PCT/GB2013/051098 WO2013164593A1 (en) 2012-04-30 2013-04-30 Pyrrolobenzodiazepines

Publications (1)

Publication Number Publication Date
ZA201407759B true ZA201407759B (en) 2015-11-25

Family

ID=48325770

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2014/07759A ZA201407759B (en) 2012-04-30 2014-10-24 Pyrrolobenzodiazepines

Country Status (14)

Country Link
US (1) US9376440B2 (https=)
EP (1) EP2855482B1 (https=)
JP (1) JP6157596B2 (https=)
KR (1) KR101960129B1 (https=)
CN (1) CN104684914B (https=)
AU (1) AU2013255613B2 (https=)
BR (1) BR112014027143B1 (https=)
CA (1) CA2871172C (https=)
ES (1) ES2623042T3 (https=)
IN (1) IN2014MN02092A (https=)
MX (1) MX369715B (https=)
NZ (1) NZ701290A (https=)
WO (1) WO2013164593A1 (https=)
ZA (1) ZA201407759B (https=)

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CN109641910A (zh) * 2016-06-24 2019-04-16 梅尔莎纳医疗公司 吡咯并苯二氮*及其缀合物
GB201617466D0 (en) 2016-10-14 2016-11-30 Medimmune Ltd Pyrrolobenzodiazepine conjugates
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MX2019011655A (es) 2017-03-29 2019-12-19 Legochem Biosciences Inc Profarmaco de dimero de pirrolobenzodiazepina y compuesto conjugado ligando-conector de este.
PT3612537T (pt) 2017-04-18 2022-08-29 Medimmune Ltd Conjugados de pirrolobenzodiazepina
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Also Published As

Publication number Publication date
CN104684914A (zh) 2015-06-03
MX2014013098A (es) 2015-04-14
JP6157596B2 (ja) 2017-07-05
CN104684914B (zh) 2017-12-15
CA2871172C (en) 2020-08-25
BR112014027143A2 (pt) 2017-06-27
AU2013255613A1 (en) 2014-11-13
CA2871172A1 (en) 2013-11-07
ES2623042T3 (es) 2017-07-10
WO2013164593A1 (en) 2013-11-07
KR101960129B1 (ko) 2019-03-19
MX369715B (es) 2019-11-20
KR20150016245A (ko) 2015-02-11
HK1208444A1 (en) 2016-03-04
EP2855482A1 (en) 2015-04-08
IN2014MN02092A (https=) 2015-09-04
US20150133435A1 (en) 2015-05-14
BR112014027143B1 (pt) 2020-06-09
JP2015515972A (ja) 2015-06-04
US9376440B2 (en) 2016-06-28
NZ701290A (en) 2016-08-26
AU2013255613B2 (en) 2017-06-22
EP2855482B1 (en) 2017-03-01

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