ZA201306175B - Isoxazole derivatives - Google Patents

Isoxazole derivatives

Info

Publication number
ZA201306175B
ZA201306175B ZA2013/06175A ZA201306175A ZA201306175B ZA 201306175 B ZA201306175 B ZA 201306175B ZA 2013/06175 A ZA2013/06175 A ZA 2013/06175A ZA 201306175 A ZA201306175 A ZA 201306175A ZA 201306175 B ZA201306175 B ZA 201306175B
Authority
ZA
South Africa
Prior art keywords
isoxazole derivatives
isoxazole
derivatives
Prior art date
Application number
ZA2013/06175A
Other languages
English (en)
Inventor
Noelle Gauvry
Steve Nanchen
Original Assignee
Novartis Tiergesundheit Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Tiergesundheit Ag filed Critical Novartis Tiergesundheit Ag
Publication of ZA201306175B publication Critical patent/ZA201306175B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/28Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
    • A01N47/38Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the group >N—CO—N< where at least one nitrogen atom is part of a heterocyclic ring; Thio analogues thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D419/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms
    • C07D419/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D419/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
ZA2013/06175A 2011-03-10 2013-08-16 Isoxazole derivatives ZA201306175B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH4072011 2011-03-10
PCT/EP2012/054161 WO2012120135A1 (en) 2011-03-10 2012-03-09 Isoxazole derivatives

Publications (1)

Publication Number Publication Date
ZA201306175B true ZA201306175B (en) 2014-04-30

Family

ID=45809012

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2013/06175A ZA201306175B (en) 2011-03-10 2013-08-16 Isoxazole derivatives

Country Status (15)

Country Link
US (1) US8822466B2 (enExample)
EP (1) EP2683713B1 (enExample)
JP (1) JP2014507459A (enExample)
CN (1) CN103502246A (enExample)
AR (1) AR085657A1 (enExample)
AU (1) AU2012224521B2 (enExample)
BR (1) BR112013022755A2 (enExample)
CA (1) CA2829149A1 (enExample)
CL (1) CL2013002472A1 (enExample)
CO (1) CO6801794A2 (enExample)
ES (1) ES2542409T3 (enExample)
MX (1) MX2013010297A (enExample)
RU (1) RU2013145304A (enExample)
WO (1) WO2012120135A1 (enExample)
ZA (1) ZA201306175B (enExample)

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CN104168900A (zh) 2012-02-06 2014-11-26 梅里亚有限公司 包含全身性地起作用的活性剂的杀寄生虫口服兽用组合物、方法及其用途
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
JP6321042B2 (ja) 2013-02-06 2018-05-09 バイエル・クロップサイエンス・アクチェンゲゼルシャフト 新規なハロゲン置換された化合物
BR112015032324B1 (pt) 2013-06-24 2020-04-07 Merial Inc compostos isotiazolina-substituído de tiofeno ou furano como pesticidas
US9944597B2 (en) 2013-09-16 2018-04-17 The Board Of Regents Of The University Of Texas System Polysubstituted pyrroles having microtubule-disrupting, cytotoxic and antitumor activities and methods of use thereof
CN105873925B (zh) 2013-11-01 2019-09-10 勃林格殷格翰动物保健美国公司 抗寄生物的和杀虫的异噁唑啉化合物
KR20160104065A (ko) 2014-01-03 2016-09-02 바이엘 애니멀 헬스 게엠베하 농약으로서의 신규 피라졸릴헤테로아릴아미드
ES2765405T3 (es) 2014-04-17 2020-06-09 Boehringer Ingelheim Animal Health Usa Inc Utilización de compuestos de malononitrilo para proteger animales de parásitos
JP2017521441A (ja) 2014-07-15 2017-08-03 バイエル・アニマル・ヘルス・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングBayer Animal Health Gmbh 有害生物防除剤としてのアリール−トリアゾリルピリジン類
MX375880B (es) 2014-10-14 2025-03-07 Syngenta Participations Ag Proceso para preparar 5-bromo-1,2,3-triclorobenceno.
WO2016058882A1 (en) * 2014-10-14 2016-04-21 Syngenta Participations Ag Process for the preparation of halo-substituted trifluoroacetophenones
KR20220051422A (ko) 2014-10-14 2022-04-26 신젠타 파티서페이션즈 아게 1-(3,5-디클로로페닐)-2,2,2-트리플루오로에타논 및 그의 유도체의 제조 방법
EP3207018B1 (en) 2014-10-14 2018-07-25 Syngenta Participations AG Process for the preparation of 1-(3,5-dichloro-4-fluoro-phenyl)-2,2,2-trifluoro-ethanone
EP3018129A1 (en) * 2014-11-10 2016-05-11 Novartis Tiergesundheit AG Diaryl isoxazoline compound
PY1609250A (es) 2015-02-26 2018-03-01 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
EP3280413A1 (en) * 2015-04-08 2018-02-14 Merial, Inc. Extended release injectable formulations comprising an isoxazoline active agent, methods and uses thereof
CN107835818B (zh) 2015-05-20 2022-04-29 勃林格殷格翰动物保健美国公司 驱虫缩酚酸肽化合物
UY37137A (es) * 2016-02-24 2017-09-29 Merial Inc Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
CN110381738B (zh) 2016-10-14 2021-07-16 勃林格殷格翰动物保健美国公司 农药的和杀寄生物的乙烯基异噁唑啉化合物
EP3541789A1 (en) 2016-11-16 2019-09-25 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic depsipeptide compounds
WO2018166855A1 (en) 2017-03-16 2018-09-20 Basf Se Heterobicyclic substituted dihydroisoxazoles
ES2944616T3 (es) 2017-08-14 2023-06-22 Boehringer Ingelheim Animal Health Usa Inc Compuestos de pirazol-isoxazolina plaguicidas y parasiticidas
MX2021000293A (es) 2018-07-09 2021-07-15 Boehringer Ingelheim Animal Health Usa Inc Compuestos heterociclicos antihelminticos.
EP3883648A1 (en) 2018-11-20 2021-09-29 Boehringer Ingelheim Animal Health USA Inc. Indazolylcyanoethylamino compound, compositions of same, method of making, and methods of using thereof
JP7637630B2 (ja) 2019-03-19 2025-02-28 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー 駆虫性アザベンゾチオフェンおよびアザベンゾフラン化合物
AR119790A1 (es) 2019-08-29 2022-01-12 Pi Industries Ltd Compuestos de isoxazolina y su uso como agentes para el control de plagas
AU2020417293A1 (en) 2020-01-03 2022-09-01 Berg Llc Polycyclic amides as UBE2K modulators for treating cancer
AU2021278871A1 (en) 2020-05-28 2023-01-19 Boehringer Ingelheim Animal Health USA Inc. Bi-modal release intra-ruminal capsule device and methods of use thereof
PH12022553222A1 (en) 2020-05-29 2024-02-12 Boehringer Ingelheim Animal Health Usa Inc Anthelmintic heterocyclic compounds
JP2024504208A (ja) 2020-12-21 2024-01-30 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー イソオキサゾリン化合物を含む殺寄生虫首輪
US20240116854A1 (en) 2021-01-27 2024-04-11 Intervet Inc. Cyclopropylamide compounds against parasites in fish
CA3209562A1 (en) 2021-01-27 2022-08-04 Intervet International B.V. Cyclopropylamide compounds against parasites in fish
NO20240925A1 (en) 2023-09-15 2025-03-17 Evah Atlantic Inc Dihydroisoxazole compound for use in reducing ectoparasite infestations on fish
WO2025257633A1 (en) 2024-06-12 2025-12-18 Boehringer Ingelheim Vetmedica Gmbh Long-acting castor oil-containing injectable formulations and methods of use thereof
US20260021076A1 (en) 2024-07-22 2026-01-22 Zoetis Services Llc Isoxazoline and macrocyclic lactone microspheres
WO2026043852A1 (en) 2024-08-20 2026-02-26 Zoetis Services Llc Process for preparing optically enriched isoxazolines

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TW200803740A (en) 2005-12-16 2008-01-16 Du Pont 5-aryl isoxazolines for controlling invertebrate pests
CN101331127B (zh) * 2005-12-16 2012-05-23 杜邦公司 用于防治无脊椎害虫的5-芳基异噁唑啉
TWI412322B (zh) * 2005-12-30 2013-10-21 Du Pont 控制無脊椎害蟲之異唑啉
JP5152518B2 (ja) * 2006-03-10 2013-02-27 日産化学工業株式会社 置換イソキサゾリン化合物及び有害生物防除剤
RU2009141185A (ru) * 2007-04-10 2011-05-20 Байер КропСайенс АГ (DE) Инсектицидные производные арилизоксазолина
TWI600639B (zh) 2007-08-17 2017-10-01 杜邦股份有限公司 製備5-鹵烷基-4,5-二氫異唑衍生物之化合物
WO2009071500A2 (en) 2007-12-03 2009-06-11 Novartis Ag Organic compounds
PL2379537T3 (pl) * 2008-12-19 2013-03-29 Elanco Tiergesundheit Ag Pochodne izooksazoliny i ich zastosowanie jako pestycydów
JP2010235590A (ja) * 2009-03-09 2010-10-21 Nissan Chem Ind Ltd 置換イソキサゾリン化合物及び有害生物防除剤
UY33403A (es) 2010-06-17 2011-12-30 Novartis Ag Compuestos orgánicos con novedosas isoxazolinas, sus n-óxidos, s-óxidos y sales

Also Published As

Publication number Publication date
US8822466B2 (en) 2014-09-02
MX2013010297A (es) 2013-10-17
CN103502246A (zh) 2014-01-08
CO6801794A2 (es) 2013-11-29
AR085657A1 (es) 2013-10-16
AU2012224521B2 (en) 2015-10-29
EP2683713B1 (en) 2015-04-22
NZ614662A (en) 2015-06-26
BR112013022755A2 (pt) 2019-09-24
JP2014507459A (ja) 2014-03-27
CA2829149A1 (en) 2012-09-13
RU2013145304A (ru) 2015-04-20
US20130345221A1 (en) 2013-12-26
CL2013002472A1 (es) 2014-03-07
AU2012224521A1 (en) 2013-09-05
ES2542409T3 (es) 2015-08-05
EP2683713A1 (en) 2014-01-15
WO2012120135A1 (en) 2012-09-13

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