JP2014507459A - イソオキサゾール誘導体 - Google Patents

イソオキサゾール誘導体 Download PDF

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Publication number
JP2014507459A
JP2014507459A JP2013557121A JP2013557121A JP2014507459A JP 2014507459 A JP2014507459 A JP 2014507459A JP 2013557121 A JP2013557121 A JP 2013557121A JP 2013557121 A JP2013557121 A JP 2013557121A JP 2014507459 A JP2014507459 A JP 2014507459A
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JP
Japan
Prior art keywords
alkyl
haloalkyl
substituted
alkoxy
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2013557121A
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English (en)
Japanese (ja)
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JP2014507459A5 (enExample
Inventor
ゴブリ，ノエル
ナンヒエン，シユテイーブ
Original Assignee
ノバルティス アーゲー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by ノバルティス アーゲー filed Critical ノバルティス アーゲー
Publication of JP2014507459A publication Critical patent/JP2014507459A/ja
Publication of JP2014507459A5 publication Critical patent/JP2014507459A5/ja
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
    • A01N47/38—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the group >N—CO—N< where at least one nitrogen atom is part of a heterocyclic ring; Thio analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D419/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms
    • C07D419/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D419/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
JP2013557121A 2011-03-10 2012-03-09 イソオキサゾール誘導体 Pending JP2014507459A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH00407/11 2011-03-10
CH4072011 2011-03-10
PCT/EP2012/054161 WO2012120135A1 (en) 2011-03-10 2012-03-09 Isoxazole derivatives

Publications (2)

Publication Number Publication Date
JP2014507459A true JP2014507459A (ja) 2014-03-27
JP2014507459A5 JP2014507459A5 (enExample) 2015-04-09

Family

ID=45809012

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013557121A Pending JP2014507459A (ja) 2011-03-10 2012-03-09 イソオキサゾール誘導体

Country Status (15)

Country Link
US (1) US8822466B2 (enExample)
EP (1) EP2683713B1 (enExample)
JP (1) JP2014507459A (enExample)
CN (1) CN103502246A (enExample)
AR (1) AR085657A1 (enExample)
AU (1) AU2012224521B2 (enExample)
BR (1) BR112013022755A2 (enExample)
CA (1) CA2829149A1 (enExample)
CL (1) CL2013002472A1 (enExample)
CO (1) CO6801794A2 (enExample)
ES (1) ES2542409T3 (enExample)
MX (1) MX2013010297A (enExample)
RU (1) RU2013145304A (enExample)
WO (1) WO2012120135A1 (enExample)
ZA (1) ZA201306175B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013530176A (ja) * 2010-06-17 2013-07-25 ノバルティス アーゲー 有害生物を防除するための５−アリールイソオキサゾリン
JP2017531004A (ja) * 2014-10-14 2017-10-19 シンジェンタ パーティシペーションズ アーゲー １−（３，５−ジクロロ−４−フルオロ−フェニル）−２，２，２−トリフルオロ−エタノンを調製するプロセス

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AP2014007874A0 (en) 2012-02-06 2014-08-31 Merial Ltd Parasiticidal oral veterinary compositions comprising systemetically- acting active agents, methods and uses thereof
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
PT2953942T (pt) 2013-02-06 2018-01-17 Bayer Cropscience Ag Derivados de pirazol substituídos com halogéneo como agentes pesticidas
WO2014206909A1 (en) 2013-06-24 2014-12-31 Basf Se Thiophene- or furan-substituted isothiazoline compounds as pesticides
US9944597B2 (en) 2013-09-16 2018-04-17 The Board Of Regents Of The University Of Texas System Polysubstituted pyrroles having microtubule-disrupting, cytotoxic and antitumor activities and methods of use thereof
WO2015066277A1 (en) 2013-11-01 2015-05-07 Merial Limited Antiparisitic and pesticidal isoxazoline compounds
WO2015101622A1 (de) 2014-01-03 2015-07-09 Bayer Cropscience Ag Neue pyrazolyl-heteroarylamide als schädlingsbekämpfungsmittel
JP6682719B2 (ja) 2014-04-17 2020-04-15 ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド 寄生生物から動物を保護するためのマロノニトリル化合物の使用
JP2017521441A (ja) 2014-07-15 2017-08-03 バイエル・アニマル・ヘルス・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒ Ａｎｉｍａｌ Ｈｅａｌｔｈ Ｇｍｂｈ 有害生物防除剤としてのアリール−トリアゾリルピリジン類
KR20220051422A (ko) * 2014-10-14 2022-04-26 신젠타 파티서페이션즈 아게 1-(3,5-디클로로페닐)-2,2,2-트리플루오로에타논 및 그의 유도체의 제조 방법
BR112017007508B1 (pt) * 2014-10-14 2021-02-02 Syngenta Participations Ag processo para a preparação de trifluoroacetofenonas substituídas por halo
KR102554861B1 (ko) 2014-10-14 2023-07-11 신젠타 파티서페이션즈 아게 5-브로모-1,2,3-트리클로로벤젠의 제조 방법
EP3018129A1 (en) * 2014-11-10 2016-05-11 Novartis Tiergesundheit AG Diaryl isoxazoline compound
UY36570A (es) * 2015-02-26 2016-10-31 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
CA2981797C (en) * 2015-04-08 2023-11-21 Merial, Inc. Extended release injectable formulations comprising an isoxazoline active agent, methods and uses thereof
RS62130B1 (sr) 2015-05-20 2021-08-31 Boehringer Ingelheim Animal Health Usa Inc Antihelmintička depsipeptidna jedinjenja
UY37137A (es) 2016-02-24 2017-09-29 Merial Inc Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
JP2019535655A (ja) 2016-10-14 2019-12-12 ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド 殺虫性及び殺寄生虫性ビニルイソオキサゾリン化合物
BR112019009977A2 (pt) 2016-11-16 2019-08-27 Boehringer Ingelheim Animal Health Usa Inc compostos depsipeptídicos anti-helmínticos
WO2018166855A1 (en) 2017-03-16 2018-09-20 Basf Se Heterobicyclic substituted dihydroisoxazoles
MX2020001724A (es) 2017-08-14 2020-07-29 Boehringer Ingelheim Animal Health Usa Inc Compuestos de pirazol-isoxazolina plaguicidas y parasiticidas.
MX2021000293A (es) 2018-07-09 2021-07-15 Boehringer Ingelheim Animal Health Usa Inc Compuestos heterociclicos antihelminticos.
US11773066B2 (en) 2018-11-20 2023-10-03 Boehringer Ingelheim Animal Health USA Inc. Indazolylcyanoethylamino compound, compositions of same, method of making, and methods of using thereof
KR20220002890A (ko) 2019-03-19 2022-01-07 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 구충성 아자-벤조티오펜 및 아자-벤조푸란 화합물
AR119790A1 (es) 2019-08-29 2022-01-12 Pi Industries Ltd Compuestos de isoxazolina y su uso como agentes para el control de plagas
WO2021138540A1 (en) 2020-01-03 2021-07-08 Berg Llc Polycyclic amides as ube2k modulators for treating cancer
WO2021242481A1 (en) 2020-05-28 2021-12-02 Boehringer Ingelheim Animal Health USA Inc. Bi-modal release intra-ruminal capsule device and methods of use thereof
BR112022024156A2 (pt) 2020-05-29 2023-02-14 Boehringer Ingelheim Animal Health Usa Inc Compostos heterocílicos antelmínticos
EP4262789A1 (en) 2020-12-21 2023-10-25 Boehringer Ingelheim Vetmedica GmbH Parasiticidal collar comprising isoxazoline compounds
US12655090B2 (en) 2021-01-27 2026-06-16 Intervet Inc. Cyclopropylamide compounds against parasites in fish
US20240316045A1 (en) 2021-01-27 2024-09-26 Intervet Inc. Cyclopropylamide compounds against parasites in fish
NO20240925A1 (en) 2023-09-15 2025-03-17 Evah Atlantic Inc Dihydroisoxazole compound for use in reducing ectoparasite infestations on fish
WO2025257633A1 (en) 2024-06-12 2025-12-18 Boehringer Ingelheim Vetmedica Gmbh Long-acting castor oil-containing injectable formulations and methods of use thereof
US20260021076A1 (en) 2024-07-22 2026-01-22 Zoetis Services Llc Isoxazoline and macrocyclic lactone microspheres
WO2026043852A1 (en) 2024-08-20 2026-02-26 Zoetis Services Llc Process for preparing optically enriched isoxazolines

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007105814A1 (ja) * 2006-03-10 2007-09-20 Nissan Chemical Industries, Ltd. 置換イソキサゾリン化合物及び有害生物防除剤
WO2010070068A2 (en) * 2008-12-19 2010-06-24 Novartis Ag Organic compounds
JP2010523604A (ja) * 2007-04-10 2010-07-15 バイエル・クロツプサイエンス・アクチエンゲゼルシヤフト 殺虫性アリールイソオキサゾリン誘導体
JP2010235590A (ja) * 2009-03-09 2010-10-21 Nissan Chem Ind Ltd 置換イソキサゾリン化合物及び有害生物防除剤

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TW200803740A (en) 2005-12-16 2008-01-16 Du Pont 5-aryl isoxazolines for controlling invertebrate pests
TWI412322B (zh) 2005-12-30 2013-10-21 杜邦股份有限公司 控制無脊椎害蟲之異唑啉
TWI649303B (zh) 2007-08-17 2019-02-01 杜邦股份有限公司 製備４-乙醯基-ｎ-〔２-側氧基-２-〔（２，２，２-三氟乙基）胺基〕乙基〕-１-萘甲醯胺之化合物及方法
WO2009071500A2 (en) 2007-12-03 2009-06-11 Novartis Ag Organic compounds
UY33403A (es) * 2010-06-17 2011-12-30 Novartis Ag Compuestos orgánicos con novedosas isoxazolinas, sus n-óxidos, s-óxidos y sales

Patent Citations (4)

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Publication number Priority date Publication date Assignee Title
WO2007105814A1 (ja) * 2006-03-10 2007-09-20 Nissan Chemical Industries, Ltd. 置換イソキサゾリン化合物及び有害生物防除剤
JP2010523604A (ja) * 2007-04-10 2010-07-15 バイエル・クロツプサイエンス・アクチエンゲゼルシヤフト 殺虫性アリールイソオキサゾリン誘導体
WO2010070068A2 (en) * 2008-12-19 2010-06-24 Novartis Ag Organic compounds
JP2010235590A (ja) * 2009-03-09 2010-10-21 Nissan Chem Ind Ltd 置換イソキサゾリン化合物及び有害生物防除剤

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013530176A (ja) * 2010-06-17 2013-07-25 ノバルティス アーゲー 有害生物を防除するための５−アリールイソオキサゾリン
JP2017531004A (ja) * 2014-10-14 2017-10-19 シンジェンタ パーティシペーションズ アーゲー １−（３，５−ジクロロ−４−フルオロ−フェニル）−２，２，２−トリフルオロ−エタノンを調製するプロセス

Also Published As

Publication number Publication date
WO2012120135A1 (en) 2012-09-13
RU2013145304A (ru) 2015-04-20
CL2013002472A1 (es) 2014-03-07
CO6801794A2 (es) 2013-11-29
ES2542409T3 (es) 2015-08-05
US8822466B2 (en) 2014-09-02
EP2683713A1 (en) 2014-01-15
BR112013022755A2 (pt) 2019-09-24
AU2012224521A1 (en) 2013-09-05
US20130345221A1 (en) 2013-12-26
NZ614662A (en) 2015-06-26
ZA201306175B (en) 2014-04-30
AU2012224521B2 (en) 2015-10-29
CA2829149A1 (en) 2012-09-13
AR085657A1 (es) 2013-10-16
EP2683713B1 (en) 2015-04-22
CN103502246A (zh) 2014-01-08
MX2013010297A (es) 2013-10-17

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