JP2014507459A - イソオキサゾール誘導体 - Google Patents

イソオキサゾール誘導体 Download PDF

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Publication number
JP2014507459A
JP2014507459A JP2013557121A JP2013557121A JP2014507459A JP 2014507459 A JP2014507459 A JP 2014507459A JP 2013557121 A JP2013557121 A JP 2013557121A JP 2013557121 A JP2013557121 A JP 2013557121A JP 2014507459 A JP2014507459 A JP 2014507459A
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JP
Japan
Prior art keywords
alkyl
haloalkyl
substituted
alkoxy
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
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JP2013557121A
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English (en)
Japanese (ja)
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JP2014507459A5 (enExample
Inventor
ゴブリ，ノエル
ナンヒエン，シユテイーブ
Original Assignee
ノバルティス アーゲー
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Application filed by ノバルティス アーゲー filed Critical ノバルティス アーゲー
Publication of JP2014507459A publication Critical patent/JP2014507459A/ja
Publication of JP2014507459A5 publication Critical patent/JP2014507459A5/ja
Pending legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
    • A01N47/38—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the group >N—CO—N< where at least one nitrogen atom is part of a heterocyclic ring; Thio analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D419/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms
    • C07D419/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D419/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
JP2013557121A 2011-03-10 2012-03-09 イソオキサゾール誘導体 Pending JP2014507459A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH00407/11 2011-03-10
CH4072011 2011-03-10
PCT/EP2012/054161 WO2012120135A1 (en) 2011-03-10 2012-03-09 Isoxazole derivatives

Publications (2)

Publication Number Publication Date
JP2014507459A true JP2014507459A (ja) 2014-03-27
JP2014507459A5 JP2014507459A5 (enExample) 2015-04-09

Family

ID=45809012

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013557121A Pending JP2014507459A (ja) 2011-03-10 2012-03-09 イソオキサゾール誘導体

Country Status (15)

Country Link
US (1) US8822466B2 (enExample)
EP (1) EP2683713B1 (enExample)
JP (1) JP2014507459A (enExample)
CN (1) CN103502246A (enExample)
AR (1) AR085657A1 (enExample)
AU (1) AU2012224521B2 (enExample)
BR (1) BR112013022755A2 (enExample)
CA (1) CA2829149A1 (enExample)
CL (1) CL2013002472A1 (enExample)
CO (1) CO6801794A2 (enExample)
ES (1) ES2542409T3 (enExample)
MX (1) MX2013010297A (enExample)
RU (1) RU2013145304A (enExample)
WO (1) WO2012120135A1 (enExample)
ZA (1) ZA201306175B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013530176A (ja) * 2010-06-17 2013-07-25 ノバルティス アーゲー 有害生物を防除するための５−アリールイソオキサゾリン
JP2017531004A (ja) * 2014-10-14 2017-10-19 シンジェンタ パーティシペーションズ アーゲー １−（３，５−ジクロロ−４−フルオロ−フェニル）−２，２，２−トリフルオロ−エタノンを調製するプロセス

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RU2763496C2 (ru) 2012-02-06 2021-12-29 БЁРИНГЕР ИНГЕЛЬХАЙМ ЭНИМАЛ ХЕЛТ ЮЭсЭй ИНК. Паразитицидные пероральные ветеринарные композиции, включающие системно действующие активные агенты, способы и применение этих композиций и способов
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
PT2953942T (pt) 2013-02-06 2018-01-17 Bayer Cropscience Ag Derivados de pirazol substituídos com halogéneo como agentes pesticidas
WO2014206909A1 (en) 2013-06-24 2014-12-31 Basf Se Thiophene- or furan-substituted isothiazoline compounds as pesticides
WO2015039073A1 (en) 2013-09-16 2015-03-19 Kellogg Glen E Polysubstituted pyrroles having microtubule-disrupting, cytotoxic and antitumor activities and methds of use thereof
AU2014342241B2 (en) 2013-11-01 2017-09-14 Boehringer Ingelheim Animal Health USA Inc. Antiparasitic and pesticidal isoxazoline compounds
BR112016017527B1 (pt) 2014-01-03 2021-01-05 Bayer Animal Health Gmbh compostos, usos de compostos, composições farmacêuticas, processo para produzir composições e método não terapêutico para controlar pragas
CN106455560B (zh) 2014-04-17 2020-12-22 勃林格殷格翰动物保健美国公司 用于保护动物免受寄生物的丙二腈化合物的用途
TW201607938A (zh) 2014-07-15 2016-03-01 拜耳作物科學股份有限公司 作為殺蟲劑之新穎芳基三唑基吡啶類
JP6686012B2 (ja) * 2014-10-14 2020-04-22 シンジェンタ パーティシペーションズ アーゲー ハロ置換トリフルオロアセトフェノンを調製する方法
KR20230117260A (ko) * 2014-10-14 2023-08-07 신젠타 파티서페이션즈 아게 1-(3,5-디클로로페닐)-2,2,2-트리플루오로에타논 및그의 유도체의 제조 방법
BR112017007751B1 (pt) 2014-10-14 2020-12-15 Syngenta Participations Ag Processo para a preparação de 5-bromo-1,2,3-triclorobenzeno
EP3018129A1 (en) * 2014-11-10 2016-05-11 Novartis Tiergesundheit AG Diaryl isoxazoline compound
UY36570A (es) * 2015-02-26 2016-10-31 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
WO2016164487A1 (en) * 2015-04-08 2016-10-13 Merial, Inc. Extended release injectable formulations comprising an isoxazoline active agent, methods and uses thereof
HUE055535T2 (hu) 2015-05-20 2021-12-28 Boehringer Ingelheim Animal Health Usa Inc Féreghajtó depszipeptid-vegyületek
UY37137A (es) 2016-02-24 2017-09-29 Merial Inc Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
CN110381738B (zh) 2016-10-14 2021-07-16 勃林格殷格翰动物保健美国公司 农药的和杀寄生物的乙烯基异噁唑啉化合物
JP2020504710A (ja) 2016-11-16 2020-02-13 ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド 駆虫性デプシペプチド化合物
WO2018166855A1 (en) 2017-03-16 2018-09-20 Basf Se Heterobicyclic substituted dihydroisoxazoles
JP2020530850A (ja) 2017-08-14 2020-10-29 ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド 殺有害生物および殺寄生生物ピラゾール−イソキサゾリン化合物
IL279977B2 (en) 2018-07-09 2024-06-01 Boehringer Ingelheim Animal Health Usa Inc Heterocyclic anthelmintic compounds
EP3883648A1 (en) 2018-11-20 2021-09-29 Boehringer Ingelheim Animal Health USA Inc. Indazolylcyanoethylamino compound, compositions of same, method of making, and methods of using thereof
WO2020191091A1 (en) 2019-03-19 2020-09-24 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic aza-benzothiophene and aza-benzofuran compounds
AR119790A1 (es) 2019-08-29 2022-01-12 Pi Industries Ltd Compuestos de isoxazolina y su uso como agentes para el control de plagas
CA3166630A1 (en) 2020-01-03 2021-07-08 Berg Llc Polycyclic amides as ube2k modulators for treating cancer
AU2021278871A1 (en) 2020-05-28 2023-01-19 Boehringer Ingelheim Animal Health USA Inc. Bi-modal release intra-ruminal capsule device and methods of use thereof
US11964977B2 (en) 2020-05-29 2024-04-23 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic heterocyclic compounds
US12161089B2 (en) 2020-12-21 2024-12-10 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal collar comprising isoxazoline compounds
US20240116854A1 (en) 2021-01-27 2024-04-11 Intervet Inc. Cyclopropylamide compounds against parasites in fish
EP4284175A1 (en) 2021-01-27 2023-12-06 Intervet International B.V. Cyclopropylamide compounds against parasites in fish
NO20240925A1 (en) 2023-09-15 2025-03-17 Evah Atlantic Inc Dihydroisoxazole compound for use in reducing ectoparasite infestations on fish

Citations (4)

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WO2007105814A1 (ja) * 2006-03-10 2007-09-20 Nissan Chemical Industries, Ltd. 置換イソキサゾリン化合物及び有害生物防除剤
WO2010070068A2 (en) * 2008-12-19 2010-06-24 Novartis Ag Organic compounds
JP2010523604A (ja) * 2007-04-10 2010-07-15 バイエル・クロツプサイエンス・アクチエンゲゼルシヤフト 殺虫性アリールイソオキサゾリン誘導体
JP2010235590A (ja) * 2009-03-09 2010-10-21 Nissan Chem Ind Ltd 置換イソキサゾリン化合物及び有害生物防除剤

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TW200803740A (en) 2005-12-16 2008-01-16 Du Pont 5-aryl isoxazolines for controlling invertebrate pests
CN101331127B (zh) * 2005-12-16 2012-05-23 杜邦公司 用于防治无脊椎害虫的5-芳基异噁唑啉
TWI412322B (zh) * 2005-12-30 2013-10-21 Du Pont 控制無脊椎害蟲之異唑啉
TWI600639B (zh) 2007-08-17 2017-10-01 杜邦股份有限公司 製備５-鹵烷基-４，５-二氫異唑衍生物之化合物
WO2009071500A2 (en) 2007-12-03 2009-06-11 Novartis Ag Organic compounds
UY33403A (es) * 2010-06-17 2011-12-30 Novartis Ag Compuestos orgánicos con novedosas isoxazolinas, sus n-óxidos, s-óxidos y sales

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WO2007105814A1 (ja) * 2006-03-10 2007-09-20 Nissan Chemical Industries, Ltd. 置換イソキサゾリン化合物及び有害生物防除剤
JP2010523604A (ja) * 2007-04-10 2010-07-15 バイエル・クロツプサイエンス・アクチエンゲゼルシヤフト 殺虫性アリールイソオキサゾリン誘導体
WO2010070068A2 (en) * 2008-12-19 2010-06-24 Novartis Ag Organic compounds
JP2010235590A (ja) * 2009-03-09 2010-10-21 Nissan Chem Ind Ltd 置換イソキサゾリン化合物及び有害生物防除剤

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013530176A (ja) * 2010-06-17 2013-07-25 ノバルティス アーゲー 有害生物を防除するための５−アリールイソオキサゾリン
JP2017531004A (ja) * 2014-10-14 2017-10-19 シンジェンタ パーティシペーションズ アーゲー １−（３，５−ジクロロ−４−フルオロ−フェニル）−２，２，２−トリフルオロ−エタノンを調製するプロセス

Also Published As

Publication number Publication date
AU2012224521B2 (en) 2015-10-29
AU2012224521A1 (en) 2013-09-05
ES2542409T3 (es) 2015-08-05
MX2013010297A (es) 2013-10-17
US8822466B2 (en) 2014-09-02
CO6801794A2 (es) 2013-11-29
CL2013002472A1 (es) 2014-03-07
CA2829149A1 (en) 2012-09-13
EP2683713B1 (en) 2015-04-22
NZ614662A (en) 2015-06-26
CN103502246A (zh) 2014-01-08
US20130345221A1 (en) 2013-12-26
WO2012120135A1 (en) 2012-09-13
BR112013022755A2 (pt) 2019-09-24
AR085657A1 (es) 2013-10-16
ZA201306175B (en) 2014-04-30
EP2683713A1 (en) 2014-01-15
RU2013145304A (ru) 2015-04-20

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