CL2013002472A1 - Compuestos derivados de isoxazolina sustituidas con heterociclos y sus sales; composición farmacéutica que comprende los compuestos; y su uso en el control de ectoparásitos en y sobre vertebrados no humanos. - Google Patents

Compuestos derivados de isoxazolina sustituidas con heterociclos y sus sales; composición farmacéutica que comprende los compuestos; y su uso en el control de ectoparásitos en y sobre vertebrados no humanos.

Info

Publication number
CL2013002472A1
CL2013002472A1 CL2013002472A CL2013002472A CL2013002472A1 CL 2013002472 A1 CL2013002472 A1 CL 2013002472A1 CL 2013002472 A CL2013002472 A CL 2013002472A CL 2013002472 A CL2013002472 A CL 2013002472A CL 2013002472 A1 CL2013002472 A1 CL 2013002472A1
Authority
CL
Chile
Prior art keywords
compounds
ectoparasites
heterocycles
salts
pharmaceutical composition
Prior art date
Application number
CL2013002472A
Other languages
English (en)
Spanish (es)
Inventor
Steve Nanchen
Noelle Gauvry
Original Assignee
Novartis Tiergesundheit Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Tiergesundheit Ag filed Critical Novartis Tiergesundheit Ag
Publication of CL2013002472A1 publication Critical patent/CL2013002472A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/28Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
    • A01N47/38Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the group >N—CO—N< where at least one nitrogen atom is part of a heterocyclic ring; Thio analogues thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D419/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms
    • C07D419/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D419/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Agronomy & Crop Science (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
CL2013002472A 2011-03-10 2013-08-27 Compuestos derivados de isoxazolina sustituidas con heterociclos y sus sales; composición farmacéutica que comprende los compuestos; y su uso en el control de ectoparásitos en y sobre vertebrados no humanos. CL2013002472A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH4072011 2011-03-10

Publications (1)

Publication Number Publication Date
CL2013002472A1 true CL2013002472A1 (es) 2014-03-07

Family

ID=45809012

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2013002472A CL2013002472A1 (es) 2011-03-10 2013-08-27 Compuestos derivados de isoxazolina sustituidas con heterociclos y sus sales; composición farmacéutica que comprende los compuestos; y su uso en el control de ectoparásitos en y sobre vertebrados no humanos.

Country Status (15)

Country Link
US (1) US8822466B2 (enExample)
EP (1) EP2683713B1 (enExample)
JP (1) JP2014507459A (enExample)
CN (1) CN103502246A (enExample)
AR (1) AR085657A1 (enExample)
AU (1) AU2012224521B2 (enExample)
BR (1) BR112013022755A2 (enExample)
CA (1) CA2829149A1 (enExample)
CL (1) CL2013002472A1 (enExample)
CO (1) CO6801794A2 (enExample)
ES (1) ES2542409T3 (enExample)
MX (1) MX2013010297A (enExample)
RU (1) RU2013145304A (enExample)
WO (1) WO2012120135A1 (enExample)
ZA (1) ZA201306175B (enExample)

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UY33403A (es) * 2010-06-17 2011-12-30 Novartis Ag Compuestos orgánicos con novedosas isoxazolinas, sus n-óxidos, s-óxidos y sales
SG11201404595TA (en) 2012-02-06 2014-09-26 Merial Ltd Parasiticidal oral veterinary compositions comprising systemically-acting active agents, methods and uses thereof
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
ES2656012T3 (es) 2013-02-06 2018-02-22 Bayer Cropscience Aktiengesellschaft Derivados de pirazol sustituidos con halógeno como pesticidas
MX374221B (es) 2013-06-24 2025-03-05 Boehringer Ingelheim Animal Health Usa Inc Compuestos de isotiazolina sustituidos con tiofeno o furano como plaguicidas.
US9944597B2 (en) 2013-09-16 2018-04-17 The Board Of Regents Of The University Of Texas System Polysubstituted pyrroles having microtubule-disrupting, cytotoxic and antitumor activities and methods of use thereof
SG11201603430XA (en) 2013-11-01 2016-05-30 Merial Ltd Antiparasitic and pesticidal isoxazoline compounds
KR20160104065A (ko) 2014-01-03 2016-09-02 바이엘 애니멀 헬스 게엠베하 농약으로서의 신규 피라졸릴헤테로아릴아미드
ES2765405T3 (es) 2014-04-17 2020-06-09 Boehringer Ingelheim Animal Health Usa Inc Utilización de compuestos de malononitrilo para proteger animales de parásitos
RU2017104717A (ru) 2014-07-15 2018-08-15 Байер Энимэл Хельс ГмбХ Арилтриазолилпиридины в качестве средств для борьбы с вредителями
MX375839B (es) * 2014-10-14 2025-03-06 Syngenta Participations Ag Proceso para la preparación de 1-(3,5-dicloro-4-fluorofenil)-2,2,2-trifluoroetanona.
CN106795093B (zh) * 2014-10-14 2019-05-28 先正达参股股份有限公司 用于制备1-(3,5-二氯苯基)-2,2,2-三氟乙酮及其衍生物的方法
US9862937B2 (en) 2014-10-14 2018-01-09 Syngenta Participations Ag Process for the preparation of halo-substituted trifluoroacetophenones
KR102554861B1 (ko) 2014-10-14 2023-07-11 신젠타 파티서페이션즈 아게 5-브로모-1,2,3-트리클로로벤젠의 제조 방법
EP3018129A1 (en) * 2014-11-10 2016-05-11 Novartis Tiergesundheit AG Diaryl isoxazoline compound
UY36570A (es) * 2015-02-26 2016-10-31 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
BR112017021073A2 (pt) 2015-04-08 2018-07-03 Merial Inc composições injetáveis de liberação prolongada compreendendo um agente ativo de isoxazolina, seus métodos e usos
US10081656B2 (en) 2015-05-20 2018-09-25 Merial, Inc. Anthelmintic depsipeptide compounds
UY37137A (es) 2016-02-24 2017-09-29 Merial Inc Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
EP3525590B1 (en) 2016-10-14 2025-08-20 Boehringer Ingelheim Vetmedica GmbH Pesticidal and parasiticidal vinyl isoxazoline compounds
EP3541789A1 (en) 2016-11-16 2019-09-25 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic depsipeptide compounds
WO2018166855A1 (en) 2017-03-16 2018-09-20 Basf Se Heterobicyclic substituted dihydroisoxazoles
CN111194316A (zh) 2017-08-14 2020-05-22 勃林格殷格翰动物保健美国公司 农药的和杀寄生物的吡唑-异噁唑啉化合物
IL279977B2 (en) 2018-07-09 2024-06-01 Boehringer Ingelheim Animal Health Usa Inc Heterocyclic anthelmintic compounds
CN113260419A (zh) 2018-11-20 2021-08-13 勃林格殷格翰动物保健美国公司 吲唑基氰基乙基氨基化合物、其组合物、其制备方法和其使用方法
CA3133100A1 (en) 2019-03-19 2020-09-24 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic aza-benzothiophene and aza-benzofuran compounds
AR119790A1 (es) 2019-08-29 2022-01-12 Pi Industries Ltd Compuestos de isoxazolina y su uso como agentes para el control de plagas
CA3166630A1 (en) 2020-01-03 2021-07-08 Berg Llc Polycyclic amides as ube2k modulators for treating cancer
WO2021242481A1 (en) 2020-05-28 2021-12-02 Boehringer Ingelheim Animal Health USA Inc. Bi-modal release intra-ruminal capsule device and methods of use thereof
MX2022015038A (es) 2020-05-29 2023-01-04 Boehringer Ingelheim Animal Health Usa Inc Compuestos heterociclicos como anthelminticos.
WO2022140728A1 (en) 2020-12-21 2022-06-30 Boehringer Ingelheim Animam Health Usa Inc. Parasiticidal collar comprising isoxazoline compounds
US20240116854A1 (en) 2021-01-27 2024-04-11 Intervet Inc. Cyclopropylamide compounds against parasites in fish
EP4284175A1 (en) 2021-01-27 2023-12-06 Intervet International B.V. Cyclopropylamide compounds against parasites in fish
NO20240925A1 (en) 2023-09-15 2025-03-17 Evah Atlantic Inc Dihydroisoxazole compound for use in reducing ectoparasite infestations on fish

Family Cites Families (10)

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Publication number Priority date Publication date Assignee Title
TW200803740A (en) 2005-12-16 2008-01-16 Du Pont 5-aryl isoxazolines for controlling invertebrate pests
CN101331127B (zh) * 2005-12-16 2012-05-23 杜邦公司 用于防治无脊椎害虫的5-芳基异噁唑啉
TWI412322B (zh) 2005-12-30 2013-10-21 Du Pont 控制無脊椎害蟲之異唑啉
PL1997813T3 (pl) * 2006-03-10 2010-10-29 Nissan Chemical Ind Ltd Podstawiony związek izoksazolinowy i środek zwalczający szkodniki
RU2009141185A (ru) * 2007-04-10 2011-05-20 Байер КропСайенс АГ (DE) Инсектицидные производные арилизоксазолина
TWI600639B (zh) 2007-08-17 2017-10-01 杜邦股份有限公司 製備5-鹵烷基-4,5-二氫異唑衍生物之化合物
WO2009071500A2 (en) 2007-12-03 2009-06-11 Novartis Ag Organic compounds
NZ593135A (en) * 2008-12-19 2013-04-26 Novartis Ag Isoxazoline derivatives and their use as pesticide
JP2010235590A (ja) * 2009-03-09 2010-10-21 Nissan Chem Ind Ltd 置換イソキサゾリン化合物及び有害生物防除剤
UY33403A (es) 2010-06-17 2011-12-30 Novartis Ag Compuestos orgánicos con novedosas isoxazolinas, sus n-óxidos, s-óxidos y sales

Also Published As

Publication number Publication date
AR085657A1 (es) 2013-10-16
CA2829149A1 (en) 2012-09-13
MX2013010297A (es) 2013-10-17
NZ614662A (en) 2015-06-26
AU2012224521B2 (en) 2015-10-29
EP2683713B1 (en) 2015-04-22
ZA201306175B (en) 2014-04-30
ES2542409T3 (es) 2015-08-05
US8822466B2 (en) 2014-09-02
US20130345221A1 (en) 2013-12-26
RU2013145304A (ru) 2015-04-20
CO6801794A2 (es) 2013-11-29
WO2012120135A1 (en) 2012-09-13
AU2012224521A1 (en) 2013-09-05
BR112013022755A2 (pt) 2019-09-24
EP2683713A1 (en) 2014-01-15
CN103502246A (zh) 2014-01-08
JP2014507459A (ja) 2014-03-27

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