ZA201206020B - Synthesis of magnolol and its analogue compounds - Google Patents
Synthesis of magnolol and its analogue compoundsInfo
- Publication number
- ZA201206020B ZA201206020B ZA2012/06020A ZA201206020A ZA201206020B ZA 201206020 B ZA201206020 B ZA 201206020B ZA 2012/06020 A ZA2012/06020 A ZA 2012/06020A ZA 201206020 A ZA201206020 A ZA 201206020A ZA 201206020 B ZA201206020 B ZA 201206020B
- Authority
- ZA
- South Africa
- Prior art keywords
- magnolol
- synthesis
- analogue compounds
- analogue
- compounds
- Prior art date
Links
- VVOAZFWZEDHOOU-UHFFFAOYSA-N magnolol Chemical compound OC1=CC=C(CC=C)C=C1C1=CC(CC=C)=CC=C1O VVOAZFWZEDHOOU-UHFFFAOYSA-N 0.000 title 2
- 230000015572 biosynthetic process Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 238000003786 synthesis reaction Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/48—Preparation of compounds having groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
- C07C37/01—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis
- C07C37/055—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis the substituted group being bound to oxygen, e.g. ether group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
- C07C37/62—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/48—Preparation of compounds having groups
- C07C41/50—Preparation of compounds having groups by reactions producing groups
- C07C41/52—Preparation of compounds having groups by reactions producing groups by substitution of halogen only
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2010/025378 WO2011106003A1 (en) | 2010-02-25 | 2010-02-25 | Synthesis of magnolol and its analogue compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA201206020B true ZA201206020B (en) | 2014-01-29 |
Family
ID=42028117
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2012/06020A ZA201206020B (en) | 2010-02-25 | 2012-08-10 | Synthesis of magnolol and its analogue compounds |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US8519197B2 (enExample) |
| EP (1) | EP2539310B1 (enExample) |
| JP (1) | JP2013520495A (enExample) |
| CN (1) | CN102884035B (enExample) |
| AR (1) | AR080656A1 (enExample) |
| AU (1) | AU2010346597B2 (enExample) |
| BR (1) | BR112012020603A2 (enExample) |
| CA (1) | CA2789140C (enExample) |
| DK (1) | DK2539310T3 (enExample) |
| ES (1) | ES2507615T3 (enExample) |
| MX (1) | MX2012009817A (enExample) |
| MY (1) | MY162466A (enExample) |
| PH (1) | PH12012501619A1 (enExample) |
| PL (1) | PL2539310T3 (enExample) |
| RU (1) | RU2510938C1 (enExample) |
| SG (1) | SG183120A1 (enExample) |
| TW (1) | TWI438185B (enExample) |
| WO (1) | WO2011106003A1 (enExample) |
| ZA (1) | ZA201206020B (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012087289A1 (en) | 2010-12-21 | 2012-06-28 | Colgate-Palmolive Company | Halogenated biphenols as antibacterial agents |
| BR112014014609B1 (pt) | 2011-12-15 | 2018-06-05 | Colgate-Palmolive Company | Composição compreendendo análogos de magnolol solubilizados. |
| CN104023698B (zh) | 2011-12-15 | 2016-10-05 | 高露洁-棕榄公司 | 溶解的厚朴酚类似物 |
| EP2794535B1 (en) | 2011-12-20 | 2016-04-20 | Colgate-Palmolive Company | Processes for making magnolol analogs |
| US9000231B2 (en) | 2011-12-20 | 2015-04-07 | Colgate-Palmolive Company | Processes for making magnolol and derivatives thereof |
| EP2948220B1 (en) | 2013-01-23 | 2018-07-04 | Colgate-Palmolive Company | Processes for making magnolol derivatives |
| JP2015007054A (ja) * | 2014-07-24 | 2015-01-15 | コルゲート・パーモリブ・カンパニーＣｏｌｇａｔｅ−Ｐａｌｍｏｌｉｖｅ Ｃｏｍｐａｎｙ | マグノロールおよびその類似体化合物の合成 |
| AU2016340992B2 (en) * | 2015-10-23 | 2020-10-08 | Colgate-Palmolive Company | Improved synthesis of honokiol |
| CN109053387B (zh) * | 2018-09-19 | 2021-07-09 | 九江学院 | 一种厚朴酚的合成方法 |
| US12311044B2 (en) | 2018-12-18 | 2025-05-27 | Conopco, Inc. | Antimicrobial composition |
| CN115581690A (zh) * | 2021-07-05 | 2023-01-10 | 北京红惠新医药科技有限公司 | 厚朴酚或和厚朴酚的芳环氨基取代衍生物在用于制备抗心肌缺血药物中的应用、药物组合物 |
| CN116139115A (zh) * | 2021-11-19 | 2023-05-23 | 北京红惠新医药科技有限公司 | 厚朴酚和/或和厚朴酚芳环氨基取代类衍生物的抗低氧/缺氧损伤用途及药物组合物 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA929051B (en) * | 1991-11-25 | 1994-05-23 | Lilly Co Eli | Substituted phenyl phenol leukotriene antagonists |
| US6544409B2 (en) | 2001-05-16 | 2003-04-08 | Petroleo Brasileiro S.A. - Petrobras | Process for the catalytic oxidation of sulfur, nitrogen and unsaturated compounds from hydrocarbon streams |
| CN1147286C (zh) * | 2001-07-18 | 2004-04-28 | 广州美晨股份有限公司 | 一种中药牙膏 |
| CN1723011A (zh) * | 2002-06-25 | 2006-01-18 | Wm·雷格利Jr·公司 | 含有厚朴提取物的口气清新和口腔清洁产品 |
| US20060140885A1 (en) | 2004-12-29 | 2006-06-29 | Abdul Gaffar | Method of reducing oral tissue inflammation using magnolia extract |
| WO2008098056A2 (en) * | 2007-02-06 | 2008-08-14 | Epix Pharmaceuticals, Inc. | High relaxivity chelates |
-
2010
- 2010-02-25 ES ES10705965.1T patent/ES2507615T3/es active Active
- 2010-02-25 CN CN201080064851.2A patent/CN102884035B/zh not_active Expired - Fee Related
- 2010-02-25 WO PCT/US2010/025378 patent/WO2011106003A1/en not_active Ceased
- 2010-02-25 US US13/577,627 patent/US8519197B2/en active Active
- 2010-02-25 EP EP10705965.1A patent/EP2539310B1/en active Active
- 2010-02-25 MY MYPI2012003487A patent/MY162466A/en unknown
- 2010-02-25 RU RU2012140748/04A patent/RU2510938C1/ru not_active IP Right Cessation
- 2010-02-25 DK DK10705965.1T patent/DK2539310T3/da active
- 2010-02-25 PH PH1/2012/501619A patent/PH12012501619A1/en unknown
- 2010-02-25 AU AU2010346597A patent/AU2010346597B2/en not_active Ceased
- 2010-02-25 SG SG2012056404A patent/SG183120A1/en unknown
- 2010-02-25 JP JP2012554971A patent/JP2013520495A/ja active Pending
- 2010-02-25 MX MX2012009817A patent/MX2012009817A/es active IP Right Grant
- 2010-02-25 PL PL10705965T patent/PL2539310T3/pl unknown
- 2010-02-25 BR BR112012020603A patent/BR112012020603A2/pt active Search and Examination
- 2010-02-25 CA CA2789140A patent/CA2789140C/en not_active Expired - Fee Related
-
2011
- 2011-02-24 TW TW100106113A patent/TWI438185B/zh not_active IP Right Cessation
- 2011-02-24 AR ARP110100579A patent/AR080656A1/es unknown
-
2012
- 2012-08-10 ZA ZA2012/06020A patent/ZA201206020B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2507615T3 (es) | 2014-10-15 |
| MY162466A (en) | 2017-06-15 |
| CN102884035A (zh) | 2013-01-16 |
| RU2012140748A (ru) | 2014-03-27 |
| AR080656A1 (es) | 2012-04-25 |
| MX2012009817A (es) | 2012-09-12 |
| TWI438185B (zh) | 2014-05-21 |
| CA2789140C (en) | 2015-01-27 |
| TW201141823A (en) | 2011-12-01 |
| US20120302647A1 (en) | 2012-11-29 |
| DK2539310T3 (da) | 2014-10-20 |
| CA2789140A1 (en) | 2011-09-01 |
| US8519197B2 (en) | 2013-08-27 |
| AU2010346597B2 (en) | 2013-09-19 |
| SG183120A1 (en) | 2012-09-27 |
| BR112012020603A2 (pt) | 2017-07-11 |
| CN102884035B (zh) | 2016-01-20 |
| HK1180297A1 (en) | 2013-10-18 |
| AU2010346597A1 (en) | 2012-08-23 |
| JP2013520495A (ja) | 2013-06-06 |
| EP2539310B1 (en) | 2014-07-16 |
| PL2539310T3 (pl) | 2015-01-30 |
| WO2011106003A1 (en) | 2011-09-01 |
| RU2510938C1 (ru) | 2014-04-10 |
| EP2539310A1 (en) | 2013-01-02 |
| PH12012501619A1 (en) | 2014-09-24 |
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