ZA201001929B - Adherent cells from adipose or placenta tissues and use thereof in thepary - Google Patents

Adherent cells from adipose or placenta tissues and use thereof in thepary

Info

Publication number
ZA201001929B
ZA201001929B ZA2010/01929A ZA201001929A ZA201001929B ZA 201001929 B ZA201001929 B ZA 201001929B ZA 2010/01929 A ZA2010/01929 A ZA 2010/01929A ZA 201001929 A ZA201001929 A ZA 201001929A ZA 201001929 B ZA201001929 B ZA 201001929B
Authority
ZA
South Africa
Prior art keywords
thepary
adipose
adherent cells
placenta tissues
placenta
Prior art date
Application number
ZA2010/01929A
Other languages
English (en)
Inventor
Nirit Drori-Carmi
Rachel Ofir
Moran Meiron
Zami Aberman
Amir Toren
Original Assignee
Pluristem Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40118825&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA201001929(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pluristem Ltd filed Critical Pluristem Ltd
Publication of ZA201001929B publication Critical patent/ZA201001929B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48Reproductive organs
    • A61K35/50Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/35Fat tissue; Adipocytes; Stromal cells; Connective tissues
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Transplantation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA2010/01929A 2007-09-19 2010-03-18 Adherent cells from adipose or placenta tissues and use thereof in thepary ZA201001929B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US96018407P 2007-09-19 2007-09-19
PCT/IL2008/001185 WO2009037690A1 (en) 2007-09-19 2008-09-02 Adherent cells from adipose or placenta tissues and use thereof in therapy

Publications (1)

Publication Number Publication Date
ZA201001929B true ZA201001929B (en) 2011-02-23

Family

ID=40118825

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2010/01929A ZA201001929B (en) 2007-09-19 2010-03-18 Adherent cells from adipose or placenta tissues and use thereof in thepary

Country Status (18)

Country Link
US (4) US8529888B2 (cg-RX-API-DMAC7.html)
EP (3) EP2591789B2 (cg-RX-API-DMAC7.html)
JP (5) JP2010539228A (cg-RX-API-DMAC7.html)
KR (4) KR101738323B1 (cg-RX-API-DMAC7.html)
CN (2) CN107050057B (cg-RX-API-DMAC7.html)
AU (1) AU2008300185B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0815946B8 (cg-RX-API-DMAC7.html)
CA (1) CA2699664C (cg-RX-API-DMAC7.html)
ES (1) ES2392729T5 (cg-RX-API-DMAC7.html)
HR (1) HRP20120887T4 (cg-RX-API-DMAC7.html)
IL (4) IL204566A (cg-RX-API-DMAC7.html)
MX (1) MX2010003019A (cg-RX-API-DMAC7.html)
PL (1) PL2200622T5 (cg-RX-API-DMAC7.html)
PT (1) PT2200622E (cg-RX-API-DMAC7.html)
RU (2) RU2010109698A (cg-RX-API-DMAC7.html)
SI (1) SI2200622T2 (cg-RX-API-DMAC7.html)
WO (1) WO2009037690A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201001929B (cg-RX-API-DMAC7.html)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060045872A1 (en) 2004-08-25 2006-03-02 Universidad Autonoma De Madrid Ciudad Universitaria de Cantoblanco Use of adipose tissue-derived stromal stem cells in treating fistula
ES2589311T5 (es) 2005-09-23 2020-02-14 Tigenix S A U Poblaciones de células que tienen actividad inmunorreguladora, método de aislamiento y usos
EP1933852B1 (en) 2005-09-27 2018-12-19 TissueTech, Inc. Amniotic membrane preparations and purified compositions and methods of use
WO2011132087A1 (en) 2010-04-23 2011-10-27 Pluristem Ltd. Adherent stromal cells derived from plancentas of multiple donors and uses thereof
KR102561664B1 (ko) 2007-07-23 2023-07-28 더 차이니즈 유니버시티 오브 홍콩 대규모 병렬 게놈 서열분석을 이용한 태아 염색체 이수성의 진단 방법
US12180549B2 (en) 2007-07-23 2024-12-31 The Chinese University Of Hong Kong Diagnosing fetal chromosomal aneuploidy using genomic sequencing
PT2200622E (pt) 2007-09-19 2012-11-06 Pluristem Ltd Células aderentes provenientes de tecido adiposo ou placentário e respetiva utilização terapêutica
WO2009042201A1 (en) * 2007-09-26 2009-04-02 Celgene Cellular Therapeutics Angiogenic cells from human placental perfusate
CN102123717A (zh) * 2008-05-27 2011-07-13 普拉里斯坦有限公司 治疗炎性结肠疾病的方法
KR20240052847A (ko) 2008-08-20 2024-04-23 셀룰래리티 인코포레이티드 개선된 세포 조성물 및 그의 제조 방법
EP2334783B1 (en) * 2008-09-02 2016-06-22 Pluristem Ltd. Adherent cells from placenta tissue and use thereof in therapy
JP5869342B2 (ja) 2008-11-19 2016-02-24 アンスロジェネシス コーポレーション 羊膜由来接着細胞
EP2977445B1 (en) 2009-11-30 2018-07-25 Pluristem Ltd. Adherent cells from placenta and use of same in disease treatment
CA2795518C (en) * 2010-04-07 2020-03-24 Anthrogenesis Corporation Angiogenesis using placental stem cells
AU2013203479B2 (en) * 2010-04-07 2016-05-19 Celularity Inc. Angiogenesis using placental stem cells
US9757419B2 (en) 2010-05-27 2017-09-12 Pluristem Ltd. Skeletal muscle regeneration using mesenchymal system cells
EP2625263B1 (en) 2010-10-08 2020-03-11 Terumo BCT, Inc. Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
EP2658557A1 (en) 2010-12-31 2013-11-06 Anthrogenesis Corporation Enhancement of placental stem cell potency using modulatory rna molecules
KR101835917B1 (ko) * 2011-03-22 2018-03-07 플루리스템 리미티드 방사선 또는 화학적 손상을 치료하는 방법들
ES2768296T3 (es) 2011-04-15 2020-06-22 Pluristem Ltd Métodos y sistemas para recoger células
WO2012149486A1 (en) 2011-04-28 2012-11-01 Tissuetech, Inc. Methods of modulating bone remodeling
DK2714059T3 (en) 2011-06-01 2019-01-21 Celularity Inc TREATMENT OF PAIN WHEN USING PLACENT STAM CELLS
KR102073530B1 (ko) 2011-06-06 2020-02-04 리제네시스 비브이비에이 중공 섬유 생물 반응기에서의 줄기 세포의 확장
US20150023926A1 (en) * 2011-07-15 2015-01-22 Anthrogenesis Corporation Treatment of radiation injury using amnion derived adherent cells
HK1202251A1 (en) 2011-11-07 2015-09-25 Hina W. Chaudhry Methods of cardiac repair
US9892230B2 (en) 2012-03-08 2018-02-13 The Chinese University Of Hong Kong Size-based analysis of fetal or tumor DNA fraction in plasma
WO2014037863A1 (en) 2012-09-04 2014-03-13 Pluristem Ltd. Methods for prevention and treatment of preeclampsia
RU2615179C2 (ru) 2012-09-06 2017-04-04 Плуристем Лтд. Устройства и способы культивирования клеток
US9662355B2 (en) 2013-01-18 2017-05-30 Mimedx Group, Inc. Methods for treating cardiac conditions
JP6581908B2 (ja) * 2013-02-12 2019-09-25 レプリセル ライフ サイエンシーズ インコーポレイテッド 腱の治療及び修復用組成物及び方法
WO2014128634A1 (en) 2013-02-20 2014-08-28 Pluristem Ltd. Gene and protein expression properties of adherent stromal cells cultured in 3d
WO2014141111A1 (en) 2013-03-14 2014-09-18 Pluristem Ltd. Methods for prevention and treatment of graft-versus-host disease
SG11201508199QA (en) * 2013-04-05 2015-11-27 Claudia Zylberberg Matrix metalloproteinases and uses thereof
WO2015004609A2 (en) 2013-07-09 2015-01-15 Pluristem Ltd. Adherent cells from placenta and use thereof in treatment of injured tendons
US10633625B2 (en) 2013-11-16 2020-04-28 Terumo Bct, Inc. Expanding cells in a bioreactor
US10052351B2 (en) 2014-01-17 2018-08-21 Mimedx Group, Inc. Method for inducing angiogenesis
US10392593B2 (en) 2014-03-04 2019-08-27 Pluristem Ltd. Systems and methods for growing and harvesting cells
CN106232800B (zh) 2014-03-25 2020-07-03 泰尔茂比司特公司 介质的被动替代
WO2016049421A1 (en) 2014-09-26 2016-03-31 Terumo Bct, Inc. Scheduled feed
EP3214171A4 (en) * 2014-10-29 2018-07-11 Sungkwang Medical Foundation Placenta-derived cells excreting c3 or c1r complement and composition containing same
US10364467B2 (en) 2015-01-13 2019-07-30 The Chinese University Of Hong Kong Using size and number aberrations in plasma DNA for detecting cancer
IL294058A (en) 2015-03-23 2022-08-01 Pluristem Ltd Use of adherent stromal cells for enhancing hematopoiesis in a subject in need thereof
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
WO2017039251A1 (ko) * 2015-08-28 2017-03-09 주식회사 차바이오텍 향상된 산후 부착형 세포 및 그의 용도
AU2017220148A1 (en) * 2016-02-18 2018-07-19 Pluristem Ltd. Methods and compositions for treating cancers and neoplasms
GB201604304D0 (en) 2016-03-14 2016-04-27 Tigenix S A U Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease
WO2017205667A1 (en) 2016-05-25 2017-11-30 Terumo Bct, Inc. Cell expansion
EP3464563B1 (en) * 2016-06-06 2021-07-28 Pluristem Ltd. Altered adherent stromal cells and methods of producing and using same
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
AU2017316682B2 (en) 2016-08-24 2020-10-15 Arthrex, Inc. Tissue use for repair of injury
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
US12234441B2 (en) 2017-03-31 2025-02-25 Terumo Bct, Inc. Cell expansion
JP7393945B2 (ja) 2017-03-31 2023-12-07 テルモ ビーシーティー、インコーポレーテッド 細胞増殖
CN106932571A (zh) * 2017-04-12 2017-07-07 广东国盛医学科技有限公司 基于rcn2标志物检测的心血管病检测方法及试剂盒
IL270114B2 (en) 2017-04-24 2024-01-01 Pluri Biotech Ltd Methods and compounds for the treatment of neurological diseases
EP3615064A4 (en) * 2017-04-25 2021-02-24 Abraham J and Phyllis Katz Cord Blood Foundation ENRICHED CELL COMPOSITIONS AND THERAPEUTIC USES
WO2019132025A1 (ja) * 2017-12-28 2019-07-04 株式会社カネカ 接着性幹細胞を含む細胞集団とその製造方法、及び医薬組成物
CN109810992A (zh) * 2019-02-01 2019-05-28 天津师范大学 一种编码牙鲆胞外ATP水解酶CD39的cDNA全长序列及其应用
KR102143840B1 (ko) * 2019-02-22 2020-08-12 송미연 손상된 성상교세포 치료방법
US11511017B2 (en) 2019-03-12 2022-11-29 Arthrex, Inc. Ligament reconstruction
US20220160787A1 (en) * 2019-03-15 2022-05-26 Celularity Inc. Placenta derived adherent cells for improved xenoplantation
WO2020194307A1 (en) * 2019-03-27 2020-10-01 Pluristem Ltd. Methods and compositions for aesthetic and cosmetic treatment and stimulating hair growth
US20200392448A1 (en) * 2019-06-14 2020-12-17 Ge Healthcare Uk Limited Monitoring of Cell Expansion
KR20200000415A (ko) * 2019-12-24 2020-01-02 (주)안트로젠 면역 질환 또는 염증성 질환의 예방 또는 치료용 중간엽줄기세포 배양액 및 이의 제조방법
JP7705950B2 (ja) 2021-03-23 2025-07-10 テルモ ビーシーティー、インコーポレーテッド 細胞を増殖する方法
WO2023037358A1 (en) * 2021-09-09 2023-03-16 Pluri Biotech Ltd. Placental cell treatment for critical limb ischemia patient subpopulations
US12209689B2 (en) 2022-02-28 2025-01-28 Terumo Kabushiki Kaisha Multiple-tube pinch valve assembly
USD1099116S1 (en) 2022-09-01 2025-10-21 Terumo Bct, Inc. Display screen or portion thereof with a graphical user interface for displaying cell culture process steps and measurements of an associated bioreactor device

Family Cites Families (112)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL154600B (nl) 1971-02-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen.
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
NL154599B (nl) 1970-12-28 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen, alsmede testverpakking.
US3901654A (en) 1971-06-21 1975-08-26 Biological Developments Receptor assays of biologically active compounds employing biologically specific receptors
US3853987A (en) 1971-09-01 1974-12-10 W Dreyer Immunological reagent and radioimmuno assay
US3867517A (en) 1971-12-21 1975-02-18 Abbott Lab Direct radioimmunoassay for antigens and their antibodies
NL171930C (nl) 1972-05-11 1983-06-01 Akzo Nv Werkwijze voor het aantonen en bepalen van haptenen, alsmede testverpakkingen.
US3850578A (en) 1973-03-12 1974-11-26 H Mcconnell Process for assaying for biologically active molecules
US3935074A (en) 1973-12-17 1976-01-27 Syva Company Antibody steric hindrance immunoassay with two antibodies
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4034074A (en) 1974-09-19 1977-07-05 The Board Of Trustees Of Leland Stanford Junior University Universal reagent 2-site immunoradiometric assay using labelled anti (IgG)
US3984533A (en) 1975-11-13 1976-10-05 General Electric Company Electrophoretic method of detecting antigen-antibody reaction
US4098876A (en) 1976-10-26 1978-07-04 Corning Glass Works Reverse sandwich immunoassay
US4879219A (en) 1980-09-19 1989-11-07 General Hospital Corporation Immunoassay utilizing monoclonal high affinity IgM antibodies
US5011771A (en) 1984-04-12 1991-04-30 The General Hospital Corporation Multiepitopic immunometric assay
US4666828A (en) 1984-08-15 1987-05-19 The General Hospital Corporation Test for Huntington's disease
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4801531A (en) 1985-04-17 1989-01-31 Biotechnology Research Partners, Ltd. Apo AI/CIII genomic polymorphisms predictive of atherosclerosis
US5902741A (en) * 1986-04-18 1999-05-11 Advanced Tissue Sciences, Inc. Three-dimensional cartilage cultures
US4846835A (en) * 1987-06-15 1989-07-11 Grande Daniel A Technique for healing lesions in cartilage
US5272057A (en) 1988-10-14 1993-12-21 Georgetown University Method of detecting a predisposition to cancer by the use of restriction fragment length polymorphism of the gene for human poly (ADP-ribose) polymerase
US5192659A (en) 1989-08-25 1993-03-09 Genetype Ag Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes
US5108989A (en) * 1990-04-04 1992-04-28 Genentech, Inc. Method of predisposing mammals to accelerated tissue repair
US5486359A (en) 1990-11-16 1996-01-23 Osiris Therapeutics, Inc. Human mesenchymal stem cells
US5281521A (en) 1992-07-20 1994-01-25 The Trustees Of The University Of Pennsylvania Modified avidin-biotin technique
US5877295A (en) * 1992-09-30 1999-03-02 The Center For Blood Research Antibodies which bind a subpopulation of Mac-1 (CD11b/CD18) molecules which mediate neutrophil adhesion to ICAM-1 and fibrinogen
US5629186A (en) 1994-04-28 1997-05-13 Lockheed Martin Corporation Porous matrix and method of its production
US5474687A (en) * 1994-08-31 1995-12-12 Activated Cell Therapy, Inc. Methods for enriching CD34+ human hematopoietic progenitor cells
US5736396A (en) 1995-01-24 1998-04-07 Case Western Reserve University Lineage-directed induction of human mesenchymal stem cell differentiation
US6132463A (en) 1995-05-19 2000-10-17 Etex Corporation Cell seeding of ceramic compositions
PT868505E (pt) 1995-11-16 2005-06-30 Univ Case Western Reserve Inducao condrogenica in vitro de celulas estaminais mesenquimais humanas
DE69903800T2 (de) 1998-03-18 2003-10-02 Massachusetts Institute Of Technology, Cambridge Vaskularisierte perfundierte anordnungen für mikrogewebe und mikroorgane
FR2784284B1 (fr) * 1998-10-13 2000-12-15 Natural Implant Sa Procede de preparation d'un implant dentaire par immersion dans une culture de cellules mesenchymateuses, dispositif de culture de cellules pour la preparation dudit implant et implant obtenu
US6153432A (en) 1999-01-29 2000-11-28 Zen-Bio, Inc Methods for the differentiation of human preadipocytes into adipocytes
JP4523169B2 (ja) 1999-02-04 2010-08-11 プルリステム リミテッド 造血幹細胞および/または前駆細胞を維持および増加するための方法および装置
KR100968164B1 (ko) * 1999-03-10 2010-07-06 더 리전츠 오브 더 유니버시티 오브 캘리포니아 지방 유래 간세포 및 격자
US7582292B2 (en) 2000-02-26 2009-09-01 Artecel, Inc. Adipose tissue derived stromal cells for the treatment of neurological disorders
CA2400485C (en) 2000-02-26 2014-04-29 Artecel Sciences, Inc. Pleuripotent stem cells generated from adipose tissue-derived stromal cells and uses thereof
ES2233650T3 (es) 2000-05-03 2005-06-16 Fidia Advanced Biopolymers S.R.L. Biomateriales formados por celulas preadipocito para reparacion de tejidos blandos.
US7311905B2 (en) * 2002-02-13 2007-12-25 Anthrogenesis Corporation Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
KR100915483B1 (ko) * 2000-12-06 2009-09-03 로버트 제이 하리리 태반 줄기 세포의 회수 방법
KR101012952B1 (ko) * 2001-02-14 2011-02-08 안트로제네시스 코포레이션 산후 포유류의 태반, 이의 용도 및 태반 줄기세포
EP2336299A1 (en) 2001-02-14 2011-06-22 Anthrogenesis Corporation Post-partum mammalian placenta, its use and placental stem cells therefrom
JP2005503801A (ja) * 2001-09-21 2005-02-10 ユニバーシティー オブ ロチェスター 幹細胞/前駆細胞の自己再生および分化の概日制御方法、ならびに時計制御遺伝子発現の概日制御方法
US9597395B2 (en) * 2001-12-07 2017-03-21 Cytori Therapeutics, Inc. Methods of using adipose tissue-derived cells in the treatment of cardiovascular conditions
US7504099B2 (en) 2001-12-27 2009-03-17 Yissum Research Development Company Of The Hebrew University Of Jerusalem Methods of inducing or enhancing connective tissue repair
KR101176146B1 (ko) 2002-02-13 2012-08-22 안트로제네시스 코포레이션 산후 포유류 태반으로부터 유래한 배아-유사 줄기 세포와그 세포를 사용한 용도 및 치료방법
JP2005517441A (ja) * 2002-02-19 2005-06-16 メディポスト・カンパニー・リミテッド 臍帯血由来の間葉幹細胞・前駆細胞の分離培養方法及び間葉組織への分化誘導方法
US7282222B2 (en) 2002-03-15 2007-10-16 The United States Of America As Represented By The Department Of Veterans Affairs Methods and compositions for directing cells to target organs
AU2003220966A1 (en) 2002-04-03 2003-10-13 Naohide Yamashita Drug containing human placenta-origin mesenchymal cells and process for producing vegf using the cells
US7498171B2 (en) * 2002-04-12 2009-03-03 Anthrogenesis Corporation Modulation of stem and progenitor cell differentiation, assays, and uses thereof
JP2005523328A (ja) * 2002-04-19 2005-08-04 ユニバーシティ オブ ピッツバーグ オブ ザ コモンウェルス システム オブ ハイヤー エデュケーション 胎盤由来の幹細胞及びその使用
US20040161419A1 (en) 2002-04-19 2004-08-19 Strom Stephen C. Placental stem cells and uses thereof
CN1234429C (zh) * 2002-05-09 2006-01-04 中国人民解放军军事医学科学院野战输血研究所 一种人工皮肤及其制备方法与应用
WO2003102151A2 (en) * 2002-05-30 2003-12-11 Celgene Corporation Modulating cell differentiation and treating myeloprolifertive disorders with jnk/mkk inhibitors
DE60328685D1 (de) * 2002-06-13 2009-09-17 Merck Patent Gmbh Verfahren für die identifizierung von allo-antigenen und ihren verwendung für krebs therapie und transplantation
US8455458B2 (en) * 2002-10-16 2013-06-04 Arthrodynamic Technologies, Animal Health Division, Inc. Composition and method for treating connective tissue damage
KR20050084921A (ko) * 2002-11-01 2005-08-29 보이스 타운 내셔널 리서치 호스피탈 α1β1 인테그린에 대한 유도성 리간드 및 이의 용도
BRPI0407694A (pt) * 2003-02-20 2006-03-01 Macropore Biosurgery Inc métodos de usar células derivadas do tecido adiposo no tratamento de condições cardiovasculares
CN1901802B (zh) 2003-02-20 2010-12-29 马克罗珀尔生物外科公司 用脂肪组织来源的细胞治疗心血管疾病的方法
JP2004254674A (ja) * 2003-02-25 2004-09-16 Mutsumi Takagi 動物細胞の分化誘導培養方法
US20060172304A1 (en) 2003-02-27 2006-08-03 Elaine Fuchs Method for modulating epithelial stem cell lineage
CN1548529A (zh) * 2003-05-09 2004-11-24 中国人民解放军军事医学科学院基础医 一种人胎盘间充质干细胞的分离方法
PL1641914T3 (pl) 2003-06-27 2017-01-31 DePuy Synthes Products, Inc. Komórki pochodzące z poporodowej tkanki łożyska oraz sposoby uzyskiwania i zastosowania tych komórek
EP1649007A4 (en) * 2003-07-17 2008-05-14 Gamida Cell Ltd PROCESS FOR THE EX-VIVO EXPANSION OF STEM / PROVIDER CELLS
DE602004030254D1 (de) 2003-08-01 2011-01-05 Two Cells Co Ltd Scaffoldfreies, selbstorganisiertes, 3 dimensionales, synthetisches gewebe
FR2859381B1 (fr) 2003-09-05 2008-07-25 Centre Nat Rech Scient Utilisaton de cellules issues du tissu adipeux pour induire la formation d'un reseau vasculaire fonctionnel
BRPI0414455A (pt) 2003-09-17 2006-11-14 Macropore Biosurgery Inc métodos para usar células regenerativas no tratamento de doença vascular periférica e distúrbios afins
TWI338714B (en) 2003-12-02 2011-03-11 Cathay General Hospital Method of isolation and enrichment of mesenchymal stem cells from amniotic fluid
US7534606B2 (en) 2004-01-12 2009-05-19 National Health Research Institutes Placental stem cell and methods thereof
US20050209231A1 (en) * 2004-01-16 2005-09-22 Xu Wu Compositions and methods for inducing cardiomyogenesis
JP4445765B2 (ja) * 2004-02-05 2010-04-07 グンゼ株式会社 細胞培養装置
AU2005227295A1 (en) 2004-03-22 2005-10-06 Osiris Therapeutics, Inc. Mesenchymal stem cells and uses therefor
WO2005113751A1 (en) * 2004-05-14 2005-12-01 Becton, Dickinson And Company Cell culture environments for the serum-free expansion of mesenchymal stem cells
CN1746296A (zh) * 2004-09-09 2006-03-15 中国人民解放军军事医学科学院基础医学研究所 一种基于胎盘来源间充质干细胞的组织工程化骨及其制造方法
CN1746295A (zh) * 2004-09-09 2006-03-15 中国人民解放军军事医学科学院基础医学研究所 一种基于胎盘来源间充质干细胞的组织工程化软骨及其制造方法
CN100336567C (zh) * 2004-10-19 2007-09-12 北京科宇联合干细胞生物技术有限公司 医用角膜贴片
JP5425399B2 (ja) 2004-12-23 2014-02-26 エシコン・インコーポレイテッド 産褥由来細胞を用いたパーキンソン病および関連の障害の治療
WO2006074075A2 (en) 2004-12-30 2006-07-13 Primegen Biotech, Llc Adipose-derived stem cells for tissue regeneration and wound healing
US20070059288A1 (en) * 2005-03-31 2007-03-15 Dinsmore Jonathan H Treatment for heart disease
JP5017253B2 (ja) 2005-03-31 2012-09-05 ステムニオン,インコーポレイテッド 羊膜由来細胞組成物、その作製方法および使用
JPWO2006112390A1 (ja) 2005-04-14 2008-12-11 国立循環器病センター総長 脂肪由来前駆細胞およびその利用
WO2006138552A2 (en) * 2005-06-15 2006-12-28 Government Of The Usa, As Represented By The Secretary, Dept. Of Health & Human Services Tissue engineered cartilage, method of making same, therapeutic and cosmetic surgical applications using same
KR101378874B1 (ko) * 2005-10-13 2014-03-27 안트로제네시스 코포레이션 태반 줄기세포를 이용한 면역 조절
ZA200803929B (en) 2005-10-13 2009-08-26 Anthrogenesis Corp Production of oligodendrocytes from placenta-derived stem cells
WO2007046775A1 (en) 2005-10-21 2007-04-26 Cellresearch Corporation Pte Ltd Isolation and cultivation of stem/progenitor cells from the amniotic membrane of umbilical cord and uses of cells differentiated therefrom
EP1979050B1 (en) * 2005-12-28 2017-04-19 DePuy Synthes Products, Inc. Treatment of peripheral vascular disease using postpartum-derived cells
PT2471907T (pt) 2005-12-29 2019-01-28 Celularity Inc Populações de células estaminais placentárias
GB0600972D0 (en) 2006-01-18 2006-03-01 Univ Leeds Enrichment of cells
EP1994143A4 (en) * 2006-02-06 2009-08-26 Pluristem Ltd METHOD AND DEVICE FOR MAINTAINING AND EXPANSION OF HEMOPOETIC STEM CELLS FROM MONONUCLEAR CELLS
PT2626417E (pt) * 2006-03-23 2015-11-16 Pluristem Ltd Métodos para expansão celular e usos de células e de meios condicionados produzidos através deles para terapia
US20110171182A1 (en) 2006-03-23 2011-07-14 Pluristem Ltd. Methods for cell expansion and uses of cells and conditioned media produced thereby for therapy
US20110293583A1 (en) 2006-03-23 2011-12-01 Pluristem Ltd. Methods for cell expansion and uses of cells and conditioned media produced thereby for therapy
WO2011132087A1 (en) 2010-04-23 2011-10-27 Pluristem Ltd. Adherent stromal cells derived from plancentas of multiple donors and uses thereof
EP1845154A1 (en) 2006-04-12 2007-10-17 RNL Bio Co., Ltd. Multipotent stem cells derived from placenta tissue and cellular therapeutic agents comprising the same
DE102006043625B4 (de) * 2006-09-12 2012-02-23 Eberhard-Karls-Universität Tübingen Universitätsklinikum Verfahren zur Isolierung und/oder Identifizierung von mesenchymalen Stammzellen (MSC)
US20080138415A1 (en) * 2006-09-26 2008-06-12 Mehboob Hussain Composition and method for producing composition for constructing tissue, and tissue construct
EP2418271A3 (en) * 2006-10-23 2015-09-30 Anthrogenesis Corporation Methods and compositions for treatment of bone defects with placental cell populations
ME01562B (me) 2007-02-12 2014-09-20 Anthrogenesis Corp Liječenje protuupalnih bolesti putem matičnih stanica posteljice
AU2008287063B2 (en) * 2007-08-09 2013-10-24 Genzyme Corporation Method of treating autoimmune disease with mesenchymal stem cells
PT2200622E (pt) 2007-09-19 2012-11-06 Pluristem Ltd Células aderentes provenientes de tecido adiposo ou placentário e respetiva utilização terapêutica
CN102123717A (zh) 2008-05-27 2011-07-13 普拉里斯坦有限公司 治疗炎性结肠疾病的方法
EP2334783B1 (en) 2008-09-02 2016-06-22 Pluristem Ltd. Adherent cells from placenta tissue and use thereof in therapy
US9096827B2 (en) 2008-09-02 2015-08-04 Pluristem Ltd. Adherent cells from placenta tissue and use thereof in therapy
EP2331957B1 (en) 2008-09-02 2016-11-02 Pluristem Ltd. Methods of selection of cells for transplantation
EP2977445B1 (en) 2009-11-30 2018-07-25 Pluristem Ltd. Adherent cells from placenta and use of same in disease treatment
US9757419B2 (en) 2010-05-27 2017-09-12 Pluristem Ltd. Skeletal muscle regeneration using mesenchymal system cells
US20140017209A1 (en) 2011-03-22 2014-01-16 Pluristem Ltd. Methods for treating radiation or chemical injury
ES2768296T3 (es) 2011-04-15 2020-06-22 Pluristem Ltd Métodos y sistemas para recoger células
WO2014037863A1 (en) 2012-09-04 2014-03-13 Pluristem Ltd. Methods for prevention and treatment of preeclampsia
RU2615179C2 (ru) 2012-09-06 2017-04-04 Плуристем Лтд. Устройства и способы культивирования клеток
SG11201501278PA (en) 2012-10-31 2015-03-30 Pluristem Ltd Method and device for thawing biological material

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