ZA201000183B - Quinazolinone compounds and methods of use thereof - Google Patents

Quinazolinone compounds and methods of use thereof

Info

Publication number
ZA201000183B
ZA201000183B ZA2010/00183A ZA201000183A ZA201000183B ZA 201000183 B ZA201000183 B ZA 201000183B ZA 2010/00183 A ZA2010/00183 A ZA 2010/00183A ZA 201000183 A ZA201000183 A ZA 201000183A ZA 201000183 B ZA201000183 B ZA 201000183B
Authority
ZA
South Africa
Prior art keywords
methods
quinazolinone compounds
quinazolinone
compounds
Prior art date
Application number
ZA2010/00183A
Other languages
English (en)
Inventor
Dan Yohannes
Rocio Palma
Shi-Chung Ng
Yousheng Guan
Ping Ye
Syed M Ali
Jifeng Liu
Mark Anthony Ashwell
Original Assignee
Arqule Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arqule Inc filed Critical Arqule Inc
Publication of ZA201000183B publication Critical patent/ZA201000183B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/90—Oxygen atoms with acyclic radicals attached in position 2 or 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA2010/00183A 2007-06-22 2010-01-11 Quinazolinone compounds and methods of use thereof ZA201000183B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94583807P 2007-06-22 2007-06-22
PCT/US2008/067571 WO2009002808A2 (en) 2007-06-22 2008-06-19 Quinazolinone compounds and methods of use thereof

Publications (1)

Publication Number Publication Date
ZA201000183B true ZA201000183B (en) 2011-03-30

Family

ID=39846620

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2010/00183A ZA201000183B (en) 2007-06-22 2010-01-11 Quinazolinone compounds and methods of use thereof

Country Status (13)

Country Link
US (1) US8232285B2 (enExample)
EP (1) EP2173724B1 (enExample)
JP (1) JP2010530885A (enExample)
KR (1) KR20100024494A (enExample)
CN (1) CN101801937A (enExample)
AU (1) AU2008268613A1 (enExample)
BR (1) BRPI0813355A2 (enExample)
CA (1) CA2704282A1 (enExample)
IL (1) IL202740A0 (enExample)
MX (1) MX2009013815A (enExample)
TW (1) TW200918069A (enExample)
WO (1) WO2009002808A2 (enExample)
ZA (1) ZA201000183B (enExample)

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US9751888B2 (en) 2013-10-04 2017-09-05 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
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US20150132575A1 (en) * 2013-11-14 2015-05-14 Honeywell International Inc. Luminescent fibers, articles including the same, and methods of forming the same
EA201691872A1 (ru) 2014-03-19 2017-04-28 Инфинити Фармасьютикалз, Инк. Гетероциклические соединения для применения в лечении pi3k-гамма-опосредованных расстройств
WO2016054491A1 (en) 2014-10-03 2016-04-07 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
CN108349985A (zh) 2015-09-14 2018-07-31 无限药品股份有限公司 异喹啉酮的固体形式、其制备方法、包含其的组合物及其使用方法
WO2017161116A1 (en) 2016-03-17 2017-09-21 Infinity Pharmaceuticals, Inc. Isotopologues of isoquinolinone and quinazolinone compounds and uses thereof as pi3k kinase inhibitors
WO2017214269A1 (en) 2016-06-08 2017-12-14 Infinity Pharmaceuticals, Inc. Heterocyclic compounds and uses thereof
TW201825465A (zh) 2016-09-23 2018-07-16 美商基利科學股份有限公司 磷脂醯肌醇3-激酶抑制劑
TW201813963A (zh) 2016-09-23 2018-04-16 美商基利科學股份有限公司 磷脂醯肌醇3-激酶抑制劑
TW201815787A (zh) 2016-09-23 2018-05-01 美商基利科學股份有限公司 磷脂醯肌醇3-激酶抑制劑
US20210188843A1 (en) * 2018-05-11 2021-06-24 The United States Of America,As Represented By The Secretary,Department Of Health And Human Services Quinoline compounds and their preparation and use as antimalarial agents
CN113354590A (zh) * 2020-03-05 2021-09-07 宁波康柏睿格医药科技有限公司 拮抗nod1/2受体信号通路的喹唑啉酮类化合物

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Also Published As

Publication number Publication date
CN101801937A (zh) 2010-08-11
CA2704282A1 (en) 2008-12-31
BRPI0813355A2 (pt) 2014-12-30
US20090130097A1 (en) 2009-05-21
WO2009002808A2 (en) 2008-12-31
MX2009013815A (es) 2010-03-01
IL202740A0 (en) 2010-06-30
EP2173724B1 (en) 2012-12-05
WO2009002808A3 (en) 2009-07-23
EP2173724A2 (en) 2010-04-14
AU2008268613A1 (en) 2008-12-31
US8232285B2 (en) 2012-07-31
TW200918069A (en) 2009-05-01
JP2010530885A (ja) 2010-09-16
KR20100024494A (ko) 2010-03-05

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