ZA200904235B - Method for the enantioselective enzymatic reduction of secodione derivatives - Google Patents

Method for the enantioselective enzymatic reduction of secodione derivatives

Info

Publication number
ZA200904235B
ZA200904235B ZA200904235A ZA200904235A ZA200904235B ZA 200904235 B ZA200904235 B ZA 200904235B ZA 200904235 A ZA200904235 A ZA 200904235A ZA 200904235 A ZA200904235 A ZA 200904235A ZA 200904235 B ZA200904235 B ZA 200904235B
Authority
ZA
South Africa
Prior art keywords
enzymatic reduction
enantioselective enzymatic
secodione derivatives
secodione
derivatives
Prior art date
Application number
ZA200904235A
Other languages
English (en)
Inventor
Antje Gupta
Anke Tschentscher
Maria Bobkova
Original Assignee
Iep Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iep Gmbh filed Critical Iep Gmbh
Publication of ZA200904235B publication Critical patent/ZA200904235B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26—Ketones
    • C12P7/38—Cyclopentanone- or cyclopentadione-containing products
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
ZA200904235A 2006-12-07 2007-12-07 Method for the enantioselective enzymatic reduction of secodione derivatives ZA200904235B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0202706A AT504542B1 (de) 2006-12-07 2006-12-07 Verfahren zur enantioselektiven enzymatischen reduktion von secodionderivaten

Publications (1)

Publication Number Publication Date
ZA200904235B true ZA200904235B (en) 2010-08-25

Family

ID=39492649

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200904235A ZA200904235B (en) 2006-12-07 2007-12-07 Method for the enantioselective enzymatic reduction of secodione derivatives

Country Status (14)

Country Link
US (2) US20110020887A1 (enExample)
EP (2) EP2410047B9 (enExample)
JP (2) JP2010511394A (enExample)
KR (2) KR101474816B1 (enExample)
CN (2) CN102382805B (enExample)
AT (2) AT504542B1 (enExample)
AU (1) AU2007327842B2 (enExample)
CA (1) CA2671319C (enExample)
ES (2) ES2386380T3 (enExample)
HU (1) HUE029907T2 (enExample)
PL (2) PL2087127T3 (enExample)
PT (1) PT2087127E (enExample)
WO (1) WO2008068030A2 (enExample)
ZA (1) ZA200904235B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI601825B (zh) * 2007-09-27 2017-10-11 Ｉｅｐ有限公司 對映異構選擇性酶催化還原中間產物之方法
BRPI0924997B1 (pt) 2009-06-22 2024-01-16 Sk Biopharmaceuticals Co., Ltd Método para preparar um composto de éster do ácido 1-aril-2- tetrazoil etil carbâmico
US8404461B2 (en) 2009-10-15 2013-03-26 SK Biopharmaceutical Co. Ltd. Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester
WO2013102619A2 (de) 2012-01-04 2013-07-11 C-Lecta Gmbh Verfahren zur reduktion eines secodion-derivats mit einer alkoholdehydrogenase
DE102012017026A1 (de) 2012-08-28 2014-03-06 Forschungszentrum Jülich GmbH Sensor für NADP(H) und Entwicklung von Alkoholdehydrogenasen
US12077801B2 (en) 2017-04-07 2024-09-03 Dsm Ip Assets B.V. Regioselective hydroxylation of isophorone
CN109112166B (zh) * 2017-06-26 2023-08-15 弈柯莱生物科技(上海)股份有限公司 酶法制备替卡格雷中间体
CN113025589B (zh) * 2021-04-21 2023-04-07 重庆第二师范学院 3α-羟基类固醇脱氢酶、编码基因及其在催化剂中的应用
WO2022238249A2 (en) * 2021-05-11 2022-11-17 Firmenich Sa Process of making gingerol compounds and their use as flavor modifiers

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1252524A (en) 1917-04-21 1918-01-08 Perry Wood W Spring-latch protector.
GB1230455A (enExample) 1967-05-22 1971-05-05
DE1768985C3 (de) 1967-07-24 1980-12-18 Takeda Chemical Industries, Ltd., Osaka (Japan) Verfahren zur Herstellung von optisch aktiven Steroid-Verbindungen, die einen am 13 ß -Kohlenstoffatom (C1 bis C4)alkylsubstituierten 17-Hydroxy-8,14-secogona-polyen- 14-on-kern enthalten
US3697379A (en) 1970-04-28 1972-10-10 American Home Prod Asymmetric reduction of seco-steroids
DE4014573C1 (enExample) 1990-05-07 1991-10-10 Forschungszentrum Juelich Gmbh, 5170 Juelich, De
JP3672307B2 (ja) 1992-03-13 2005-07-20 フォルシュングスツェントルム・ユーリッヒ・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 新規ケトエステル‐還元酵素，その製造方法及びこれを酵素酸化還元反応に使用する方法
CA2103932A1 (en) * 1992-11-05 1994-05-06 Ramesh N. Patel Stereoselective reduction of ketones
JP3574682B2 (ja) 1993-09-24 2004-10-06 ダイセル化学工業株式会社 新規な酵素、該酵素を製造する方法、該酵素をコードするｄｎａ、該ｄｎａを含む形質転換体、該酵素による光学活性アルコール等の製造方法
DE19610894A1 (de) 1996-03-20 1997-09-25 Leybold Ag Vorrichtung zum Ziehen von Einkristallen aus einer in einem Tiegel befindlichen Schmelze
DE19610984A1 (de) 1996-03-21 1997-09-25 Boehringer Mannheim Gmbh Alkohol-Dehydrogenase und deren Verwendung zur enzymatischen Herstellung chiraler Hydroxyverbindungen
ATE291616T1 (de) * 1999-12-03 2005-04-15 Kaneka Corp Neue carbonyl-reduktase, gen davon und verfahren der anwendung derselben
DE10119274A1 (de) 2001-04-20 2002-10-31 Juelich Enzyme Products Gmbh Enzymatisches Verfahren zur enantioselektiven Reduktion von Ketoverbindungen
DE10327454A1 (de) * 2003-06-18 2005-01-20 Juelich Enzyme Products Gmbh Oxidoreduktase aus Pichia capsulata
AT501496B1 (de) * 2005-02-21 2007-03-15 Iep Gmbh Verfahren zur enantioselektiven enzymatischen reduktion von ketoverbindungen
DE102005044736A1 (de) * 2005-09-19 2007-03-22 Basf Ag Neue Dehydrogenasen, deren Derivate und ein Verfahren zur Herstellung von optisch aktiven Alkanolen
AT503017B1 (de) * 2005-12-19 2007-07-15 Iep Gmbh Verfahren zur enantioselektiven enzymatischen reduktion von hydroxyketoverbindungen

Also Published As

Publication number Publication date
KR101474816B1 (ko) 2014-12-19
KR101445191B1 (ko) 2014-10-16
PL2087127T3 (pl) 2012-11-30
JP2010511394A (ja) 2010-04-15
US8323936B2 (en) 2012-12-04
AT504542A1 (de) 2008-06-15
EP2410047A1 (de) 2012-01-25
WO2008068030A3 (de) 2008-12-18
EP2410047B1 (de) 2016-06-01
CA2671319C (en) 2016-02-23
US20110020887A1 (en) 2011-01-27
AT504542B1 (de) 2008-09-15
KR20090096511A (ko) 2009-09-10
HUE029907T2 (hu) 2017-04-28
ES2588706T3 (es) 2016-11-04
CN101595224B (zh) 2014-04-02
CN101595224A (zh) 2009-12-02
ATE554181T1 (de) 2012-05-15
US20120040424A1 (en) 2012-02-16
EP2410047B9 (de) 2016-08-24
EP2087127B1 (de) 2012-04-18
AU2007327842B2 (en) 2013-02-28
EP2087127A2 (de) 2009-08-12
JP2012005497A (ja) 2012-01-12
ES2386380T3 (es) 2012-08-20
CN102382805A (zh) 2012-03-21
KR20110107874A (ko) 2011-10-04
PT2087127E (pt) 2012-06-20
CA2671319A1 (en) 2008-06-12
WO2008068030A2 (de) 2008-06-12
CN102382805B (zh) 2015-03-25
PL2410047T3 (pl) 2016-12-30
AU2007327842A1 (en) 2008-06-12
JP5627546B2 (ja) 2014-11-19

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