ZA200901983B - Polycyclic agents for the treatment of respiratory syncytial virus infections - Google Patents

Polycyclic agents for the treatment of respiratory syncytial virus infections

Info

Publication number
ZA200901983B
ZA200901983B ZA200901983A ZA200901983A ZA200901983B ZA 200901983 B ZA200901983 B ZA 200901983B ZA 200901983 A ZA200901983 A ZA 200901983A ZA 200901983 A ZA200901983 A ZA 200901983A ZA 200901983 B ZA200901983 B ZA 200901983B
Authority
ZA
South Africa
Prior art keywords
treatment
respiratory syncytial
syncytial virus
virus infections
polycyclic
Prior art date
Application number
ZA200901983A
Other languages
English (en)
Inventor
Jeffrey Peter Mitchell
Alistair George Draffan
Vanessa Anne Sanford
Silas Bond
Chin Yu Lim
Penelope Anne Mayes
Original Assignee
Biota Scient Management
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biota Scient Management filed Critical Biota Scient Management
Publication of ZA200901983B publication Critical patent/ZA200901983B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/42—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA200901983A 2006-09-28 2009-03-20 Polycyclic agents for the treatment of respiratory syncytial virus infections ZA200901983B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US84807306P 2006-09-28 2006-09-28

Publications (1)

Publication Number Publication Date
ZA200901983B true ZA200901983B (en) 2010-03-31

Family

ID=39229629

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200901983A ZA200901983B (en) 2006-09-28 2009-03-20 Polycyclic agents for the treatment of respiratory syncytial virus infections

Country Status (22)

Country Link
US (2) US8598194B2 (he)
EP (1) EP2069353B1 (he)
JP (1) JP5340943B2 (he)
KR (1) KR101488826B1 (he)
CN (1) CN101583614B (he)
AR (1) AR063038A1 (he)
AT (1) ATE532787T1 (he)
AU (1) AU2007302611C1 (he)
BR (1) BRPI0717536A2 (he)
CA (1) CA2664376C (he)
DK (1) DK2069353T3 (he)
ES (1) ES2376915T3 (he)
HK (1) HK1131988A1 (he)
IL (1) IL197783A (he)
MX (1) MX2009003336A (he)
NO (1) NO20091521L (he)
NZ (1) NZ575805A (he)
PL (1) PL2069353T3 (he)
PT (1) PT2069353E (he)
TW (1) TWI423972B (he)
WO (1) WO2008037011A1 (he)
ZA (1) ZA200901983B (he)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602004031258D1 (de) 2003-12-24 2011-03-10 Biota Scient Management Polycyclische mittel zur behandlung von infektione
TWI423972B (zh) 2006-09-28 2014-01-21 Biota Scient Management 治療呼吸系融合細胞病毒感染之多環劑
TWI508968B (zh) * 2010-02-08 2015-11-21 Biota Scient Management 用於治療呼吸道融合性病毒感染的化合物
US8796303B2 (en) * 2010-11-26 2014-08-05 Biota Scientific Management Pty Ltd. Imidazo[2,1-G][1,7]naphthyridines for treating respiratory syncytial virus infections
AU2012292947B2 (en) * 2011-08-05 2017-02-16 Biota Scientific Management Pty Ltd Compounds for treating respiratory syncytial virus infections
JP2015501327A (ja) * 2011-11-04 2015-01-15 シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト 殺虫化合物
US10118890B2 (en) 2014-10-10 2018-11-06 The Research Foundation For The State University Of New York Trifluoromethoxylation of arenes via intramolecular trifluoromethoxy group migration

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FR1580180A (he) 1967-03-14 1969-09-05
CH482697A (de) 1967-03-17 1969-12-15 Geigy Ag J R Verfahren zur Herstellung von neuen, kondensierten heterocyclischen Verbindungen
US3885037A (en) * 1968-09-05 1975-05-20 American Home Prod Method of producing anorexia using imidazolinyl phenyl carbonyl compounds, their acid addition salts and related compounds
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Also Published As

Publication number Publication date
US20140004111A1 (en) 2014-01-02
NZ575805A (en) 2012-03-30
RU2009115872A (ru) 2010-11-10
IL197783A0 (en) 2009-12-24
MX2009003336A (es) 2009-05-28
ATE532787T1 (de) 2011-11-15
JP5340943B2 (ja) 2013-11-13
US20100021458A1 (en) 2010-01-28
CA2664376C (en) 2015-06-02
US8598194B2 (en) 2013-12-03
AU2007302611B2 (en) 2013-06-20
IL197783A (he) 2014-01-30
ES2376915T3 (es) 2012-03-20
KR101488826B1 (ko) 2015-02-03
JP2010504915A (ja) 2010-02-18
KR20090073212A (ko) 2009-07-02
CN101583614B (zh) 2014-01-22
PL2069353T3 (pl) 2012-04-30
TW200831505A (en) 2008-08-01
CA2664376A1 (en) 2008-04-03
TWI423972B (zh) 2014-01-21
AU2007302611C1 (en) 2013-11-21
CN101583614A (zh) 2009-11-18
US9675694B2 (en) 2017-06-13
AU2007302611A1 (en) 2008-04-03
BRPI0717536A2 (pt) 2013-10-22
HK1131988A1 (en) 2010-02-12
EP2069353B1 (en) 2011-11-09
PT2069353E (pt) 2012-02-06
EP2069353A1 (en) 2009-06-17
AR063038A1 (es) 2008-12-23
WO2008037011A1 (en) 2008-04-03
EP2069353A4 (en) 2010-09-15
DK2069353T3 (da) 2012-02-20
NO20091521L (no) 2009-04-21

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