ZA200900191B - Cyanocobalamin low viscosity aqueous formulations for intranasal delivery - Google Patents

Cyanocobalamin low viscosity aqueous formulations for intranasal delivery

Info

Publication number
ZA200900191B
ZA200900191B ZA2009/00191A ZA200900191A ZA200900191B ZA 200900191 B ZA200900191 B ZA 200900191B ZA 2009/00191 A ZA2009/00191 A ZA 2009/00191A ZA 200900191 A ZA200900191 A ZA 200900191A ZA 200900191 B ZA200900191 B ZA 200900191B
Authority
ZA
South Africa
Prior art keywords
cyanocobalamin
low viscosity
aqueous formulations
intranasal delivery
viscosity aqueous
Prior art date
Application number
ZA2009/00191A
Other languages
English (en)
Inventor
Steven C Quay
Zenaida Go
Peter C Aprile
Antony P Sileno
Original Assignee
Qol Medical Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Qol Medical Llc filed Critical Qol Medical Llc
Publication of ZA200900191B publication Critical patent/ZA200900191B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135—Compounds containing heavy metals
    • A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Otolaryngology (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA2009/00191A 2006-06-23 2009-01-09 Cyanocobalamin low viscosity aqueous formulations for intranasal delivery ZA200900191B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2006/024685 WO2007149098A1 (en) 2006-06-23 2006-06-23 Cyanocobalamin low viscosity aqueous formulations for intranasal delivery

Publications (1)

Publication Number Publication Date
ZA200900191B true ZA200900191B (en) 2012-09-26

Family

ID=38833714

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2009/00191A ZA200900191B (en) 2006-06-23 2009-01-09 Cyanocobalamin low viscosity aqueous formulations for intranasal delivery

Country Status (10)

Country Link
EP (1) EP2035441A4 (he)
JP (1) JP5769924B2 (he)
KR (3) KR20170098977A (he)
CN (1) CN101600729A (he)
AU (1) AU2006344733B2 (he)
CA (1) CA2656823C (he)
IL (2) IL196038A (he)
NO (1) NO20090368L (he)
WO (1) WO2007149098A1 (he)
ZA (1) ZA200900191B (he)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2686299T3 (es) * 2010-10-29 2018-10-17 Troikaa Pharmaceuticals Ltd Composiciones nasales de vitamina B12
EP3589269B1 (en) * 2017-03-02 2021-04-07 Dutch Renewable Energy B.V. Intranasal administration of physiologically active substances
CA3187753A1 (en) * 2020-07-29 2022-02-03 Lido Ventures Llc Apparatus, system, and method for facilitating intranasal treatment of a patient

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4724231A (en) * 1985-04-16 1988-02-09 Nastech Pharmaceutical, Inc. Nasel compositions containing vitamin B12
DE3682862D1 (de) * 1985-04-16 1992-01-23 Nastech Pharm Co Aerosolmittel zur nasenverstaeubung von vitamin b 12.
US5112804A (en) * 1987-04-01 1992-05-12 Temple University Of The Commonwealth System Of Higher Education Pharmaceutical composition and method of intranasal administration
US4959176A (en) * 1988-04-29 1990-09-25 Beckman Instruments, Inc. High resolution non corrosive amino acid analysis buffer solutions
US5227311A (en) * 1988-10-11 1993-07-13 Abbott Laboratories Intrinsic factor to determine B12
BE1007839A6 (nl) * 1993-12-20 1995-10-31 Merkus Franciscus W H M Prof Farmaceutische compositie voor de nasale toediening van hydroxocobalamine.
US6406730B1 (en) * 1998-12-01 2002-06-18 Carl E. Banyard Process for producing low acid food products
FR2787029A1 (fr) * 1998-12-09 2000-06-16 Biovector Therapeutics Utilisation dans une composition pharmaceutique pour l'administration par voie nasale de vitamine b12 pour la delivrance d'agents actifs au systeme nerveux central
WO2002024165A2 (en) * 2000-09-20 2002-03-28 Nycomed Pharma As Preparation of vitamin emulsions and concentrates thereof
US20060074034A1 (en) * 2001-09-17 2006-04-06 Collins Douglas A Cobalamin mediated delivery of nucleic acids, analogs and derivatives thereof
US6911434B2 (en) * 2002-02-04 2005-06-28 Corixa Corporation Prophylactic and therapeutic treatment of infectious and other diseases with immunoeffector compounds
US20040109826A1 (en) * 2002-12-06 2004-06-10 Dey, L.P. Stabilized albuterol compositions and method of preparation thereof
DE10300719A1 (de) * 2003-01-11 2004-07-22 Basf Ag Verbessertes Verfahren zur Herstellung von Vitamin B12
US20060127320A1 (en) * 2004-05-10 2006-06-15 Nastech Pharmaceutical Company Inc. Method of delivering parathyroid hormone to a human
US20060046969A1 (en) * 2004-08-25 2006-03-02 Aegis Therapeutics Llc Antibacterial compositions for drug administration
US20070111964A1 (en) * 2005-08-17 2007-05-17 Fleming And Company, Pharmaceuticals Vitamin B12 nasal spray and method of use

Also Published As

Publication number Publication date
CN101600729A (zh) 2009-12-09
IL196038A (he) 2016-10-31
IL196038A0 (en) 2009-09-01
CA2656823C (en) 2015-02-03
AU2006344733A1 (en) 2007-12-27
CA2656823A1 (en) 2007-12-27
IL248447B (he) 2021-10-31
AU2006344733B2 (en) 2014-02-27
EP2035441A4 (en) 2013-01-16
KR20170098977A (ko) 2017-08-30
WO2007149098A1 (en) 2007-12-27
JP2009541312A (ja) 2009-11-26
EP2035441A1 (en) 2009-03-18
KR20140101010A (ko) 2014-08-18
IL248447A0 (he) 2016-11-30
KR20090074722A (ko) 2009-07-07
NO20090368L (no) 2009-03-23
JP5769924B2 (ja) 2015-08-26

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