AU2006344733B2 - Cyanocobalamin low viscosity aqueous formulations for intranasal delivery - Google Patents

Cyanocobalamin low viscosity aqueous formulations for intranasal delivery Download PDF

Info

Publication number
AU2006344733B2
AU2006344733B2 AU2006344733A AU2006344733A AU2006344733B2 AU 2006344733 B2 AU2006344733 B2 AU 2006344733B2 AU 2006344733 A AU2006344733 A AU 2006344733A AU 2006344733 A AU2006344733 A AU 2006344733A AU 2006344733 B2 AU2006344733 B2 AU 2006344733B2
Authority
AU
Australia
Prior art keywords
cyanocobalamin
solution
concentration
spray
vitamin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2006344733A
Other languages
English (en)
Other versions
AU2006344733A1 (en
Inventor
Peter C. Aprile
Zenaida O. Go
Steven C. Quay
Antony P. Sileno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Par Pharmaceuticals Inc
Original Assignee
Par Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Par Pharmaceuticals Inc filed Critical Par Pharmaceuticals Inc
Publication of AU2006344733A1 publication Critical patent/AU2006344733A1/en
Assigned to QOL MEDICAL, LLC reassignment QOL MEDICAL, LLC Request for Assignment Assignors: NASTECH PHARMACEUTICAL COMPANY, INC.
Assigned to PAR PHARMACEUTICAL, INC. reassignment PAR PHARMACEUTICAL, INC. Request for Assignment Assignors: QOL MEDICAL, LLC
Application granted granted Critical
Publication of AU2006344733B2 publication Critical patent/AU2006344733B2/en
Priority to AU2014202415A priority Critical patent/AU2014202415B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7135—Compounds containing heavy metals
    • A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Otolaryngology (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU2006344733A 2006-06-23 2006-06-23 Cyanocobalamin low viscosity aqueous formulations for intranasal delivery Ceased AU2006344733B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2014202415A AU2014202415B2 (en) 2006-06-23 2014-05-02 Cyanocobalamin low viscosity aqueous formulations for intranasal delivery

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2006/024685 WO2007149098A1 (en) 2006-06-23 2006-06-23 Cyanocobalamin low viscosity aqueous formulations for intranasal delivery

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2014202415A Division AU2014202415B2 (en) 2006-06-23 2014-05-02 Cyanocobalamin low viscosity aqueous formulations for intranasal delivery

Publications (2)

Publication Number Publication Date
AU2006344733A1 AU2006344733A1 (en) 2007-12-27
AU2006344733B2 true AU2006344733B2 (en) 2014-02-27

Family

ID=38833714

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2006344733A Ceased AU2006344733B2 (en) 2006-06-23 2006-06-23 Cyanocobalamin low viscosity aqueous formulations for intranasal delivery

Country Status (10)

Country Link
EP (1) EP2035441A4 (he)
JP (1) JP5769924B2 (he)
KR (3) KR20170098977A (he)
CN (1) CN101600729A (he)
AU (1) AU2006344733B2 (he)
CA (1) CA2656823C (he)
IL (2) IL196038A (he)
NO (1) NO20090368L (he)
WO (1) WO2007149098A1 (he)
ZA (1) ZA200900191B (he)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2632430T3 (pl) * 2010-10-29 2018-11-30 Troikaa Pharmaceuticals Ltd Kompozycje donosowe witaminy B12
ES2880474T3 (es) * 2017-03-02 2021-11-24 Dutch Renewable Energy B V Administración intranasal de sustancias fisiológicamente activas
WO2022026762A1 (en) * 2020-07-29 2022-02-03 Lido Ventures Llc Apparatus, system, and method for facilitating intranasal treatment of a patient

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040043043A1 (en) * 2000-09-20 2004-03-04 Schlyter Jimmy Hirschsprung Preparation of emulsions and concentrates thereof

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0218679B1 (en) * 1985-04-16 1991-12-11 Nastech Pharmaceutical Company, Inc. Aerosol compositions for nasal delivery of vitamin b 12
US4724231A (en) * 1985-04-16 1988-02-09 Nastech Pharmaceutical, Inc. Nasel compositions containing vitamin B12
US5112804A (en) * 1987-04-01 1992-05-12 Temple University Of The Commonwealth System Of Higher Education Pharmaceutical composition and method of intranasal administration
US4959176A (en) * 1988-04-29 1990-09-25 Beckman Instruments, Inc. High resolution non corrosive amino acid analysis buffer solutions
US5227311A (en) * 1988-10-11 1993-07-13 Abbott Laboratories Intrinsic factor to determine B12
BE1007839A6 (nl) * 1993-12-20 1995-10-31 Merkus Franciscus W H M Prof Farmaceutische compositie voor de nasale toediening van hydroxocobalamine.
US6406730B1 (en) * 1998-12-01 2002-06-18 Carl E. Banyard Process for producing low acid food products
FR2787029A1 (fr) * 1998-12-09 2000-06-16 Biovector Therapeutics Utilisation dans une composition pharmaceutique pour l'administration par voie nasale de vitamine b12 pour la delivrance d'agents actifs au systeme nerveux central
US20060074034A1 (en) * 2001-09-17 2006-04-06 Collins Douglas A Cobalamin mediated delivery of nucleic acids, analogs and derivatives thereof
US6911434B2 (en) * 2002-02-04 2005-06-28 Corixa Corporation Prophylactic and therapeutic treatment of infectious and other diseases with immunoeffector compounds
US20040109826A1 (en) * 2002-12-06 2004-06-10 Dey, L.P. Stabilized albuterol compositions and method of preparation thereof
DE10300719A1 (de) * 2003-01-11 2004-07-22 Basf Ag Verbessertes Verfahren zur Herstellung von Vitamin B12
US20060127320A1 (en) * 2004-05-10 2006-06-15 Nastech Pharmaceutical Company Inc. Method of delivering parathyroid hormone to a human
US20060046969A1 (en) * 2004-08-25 2006-03-02 Aegis Therapeutics Llc Antibacterial compositions for drug administration
JP2009504767A (ja) * 2005-08-17 2009-02-05 フレミング・アンド・カンパニー・ファーマシューティカルズ ビタミンｂ１２鼻用スプレーおよび使用方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040043043A1 (en) * 2000-09-20 2004-03-04 Schlyter Jimmy Hirschsprung Preparation of emulsions and concentrates thereof

Also Published As

Publication number Publication date
CA2656823C (en) 2015-02-03
KR20140101010A (ko) 2014-08-18
WO2007149098A1 (en) 2007-12-27
IL248447A0 (he) 2016-11-30
IL196038A0 (en) 2009-09-01
EP2035441A4 (en) 2013-01-16
IL248447B (he) 2021-10-31
EP2035441A1 (en) 2009-03-18
JP5769924B2 (ja) 2015-08-26
ZA200900191B (en) 2012-09-26
AU2006344733A1 (en) 2007-12-27
CN101600729A (zh) 2009-12-09
KR20170098977A (ko) 2017-08-30
KR20090074722A (ko) 2009-07-07
IL196038A (he) 2016-10-31
JP2009541312A (ja) 2009-11-26
CA2656823A1 (en) 2007-12-27
NO20090368L (no) 2009-03-23

Similar Documents

Publication Publication Date Title
US20190216842A1 (en) Vitamin b12 nasal spray and method of use
EP4104848A1 (en) Safe desmopressin administration
US9415007B2 (en) Cyanocobalamin low viscosity aqueous formulations for intranasal delivery
AU2006344733B2 (en) Cyanocobalamin low viscosity aqueous formulations for intranasal delivery
EP2381923B2 (en) Intranasal desmopressin administration
US20200390691A1 (en) Compositions, devices, and methods for the treatment of overdose and reward-based disorders
US7229636B1 (en) Cyanocobalamin low viscosity aqueous formulations for intranasal delivery
AU2014202415B2 (en) Cyanocobalamin low viscosity aqueous formulations for intranasal delivery
US20060039869A1 (en) Intranasal delivery of antipsychotic drugs
CA2863377C (en) Cyanocobalamin low viscosity aqueous formulations for intranasal delivery
JP6097787B2 (ja) 鼻内送達用シアノコバラミン低粘度水性製剤
JP5797227B2 (ja) 鼻内送達用シアノコバラミン低粘度水性製剤
CA3124202A1 (en) Compositions, devices, and methods for the treatment of overdose and reward-based disorders
Feller et al. Vitamin B 12 nasal spray and method of use

Legal Events

Date Code Title Description
PC1 Assignment before grant (sect. 113)

Owner name: QOL MEDICAL, LLC

Free format text: FORMER APPLICANT(S): NASTECH PHARMACEUTICAL COMPANY, INC.

PC1 Assignment before grant (sect. 113)

Owner name: PAR PHARMACEUTICAL, INC.

Free format text: FORMER APPLICANT(S): QOL MEDICAL, LLC

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired