ATE70180T1 - Aerosolmittel zur nasenverstaeubung von vitamin b 12. - Google Patents
Aerosolmittel zur nasenverstaeubung von vitamin b 12.Info
- Publication number
- ATE70180T1 ATE70180T1 AT86902640T AT86902640T ATE70180T1 AT E70180 T1 ATE70180 T1 AT E70180T1 AT 86902640 T AT86902640 T AT 86902640T AT 86902640 T AT86902640 T AT 86902640T AT E70180 T1 ATE70180 T1 AT E70180T1
- Authority
- AT
- Austria
- Prior art keywords
- vitamin
- aerosol
- dusting
- nose
- administration
- Prior art date
Links
- 239000000443 aerosol Substances 0.000 title abstract 2
- 229940088594 vitamin Drugs 0.000 title 1
- 229930003231 vitamin Natural products 0.000 title 1
- 235000013343 vitamin Nutrition 0.000 title 1
- 239000011782 vitamin Substances 0.000 title 1
- 150000003722 vitamin derivatives Chemical class 0.000 title 1
- 229930003779 Vitamin B12 Natural products 0.000 abstract 1
- FDJOLVPMNUYSCM-WZHZPDAFSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+3].N#[C-].N([C@@H]([C@]1(C)[N-]\C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C(\C)/C1=N/C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C\C1=N\C([C@H](C1(C)C)CCC(N)=O)=C/1C)[C@@H]2CC(N)=O)=C\1[C@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]1[C@@H](O)[C@@H](N2C3=CC(C)=C(C)C=C3N=C2)O[C@@H]1CO FDJOLVPMNUYSCM-WZHZPDAFSA-L 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000011715 vitamin B12 Substances 0.000 abstract 1
- 235000019163 vitamin B12 Nutrition 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7135—Compounds containing heavy metals
- A61K31/714—Cobalamins, e.g. cyanocobalamin, i.e. vitamin B12
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Otolaryngology (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72385985A | 1985-04-16 | 1985-04-16 | |
| EP86902640A EP0218679B1 (de) | 1985-04-16 | 1986-04-02 | Aerosolmittel zur nasenverstäubung von vitamin b 12 |
| PCT/US1986/000665 WO1986005987A1 (en) | 1985-04-16 | 1986-04-02 | Aerosol compositions for nasal delivery of vitamin b12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE70180T1 true ATE70180T1 (de) | 1991-12-15 |
Family
ID=24907989
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT86902640T ATE70180T1 (de) | 1985-04-16 | 1986-04-02 | Aerosolmittel zur nasenverstaeubung von vitamin b 12. |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0218679B1 (de) |
| JP (1) | JPS62500788A (de) |
| AT (1) | ATE70180T1 (de) |
| CA (1) | CA1317881C (de) |
| DE (1) | DE3682862D1 (de) |
| WO (1) | WO1986005987A1 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0338670B1 (de) * | 1988-03-22 | 1994-05-11 | FISONS plc | Pharmazeutische Mischungen |
| JPH05213759A (ja) * | 1992-02-05 | 1993-08-24 | All Yakuhin Kogyo Kk | 安定なビタミンｂ１２含有内用液剤 |
| WO1994013252A1 (en) * | 1992-12-10 | 1994-06-23 | Hemogen, Inc. | Method for stimulating production of heme oxygenase using vitamin b12 |
| ES2074396B1 (es) * | 1993-03-24 | 1996-04-01 | Farmalider Sa | Sistema de administracion nasal de cianocobalamina (vitamina b12). |
| BE1007839A6 (nl) * | 1993-12-20 | 1995-10-31 | Merkus Franciscus W H M Prof | Farmaceutische compositie voor de nasale toediening van hydroxocobalamine. |
| US5925625A (en) * | 1994-05-13 | 1999-07-20 | Merkus; Franciscus W. H. M. | Pharmaceutical composition for the intranasal administration of hydroxocobalamin |
| US7229636B1 (en) | 2003-03-04 | 2007-06-12 | Nastech Pharmaceutical Company Inc. | Cyanocobalamin low viscosity aqueous formulations for intranasal delivery |
| US7404489B1 (en) | 2003-03-04 | 2008-07-29 | Qol Medical, Llc | Cyanocobalamin low viscosity aqueous formulations for intranasal delivery |
| CA2575706A1 (en) * | 2004-08-02 | 2006-02-23 | Bebaas, Inc. | Vitamin b12 compositions |
| WO2007022345A2 (en) | 2005-08-17 | 2007-02-22 | Fleming And Company, Pharmaceuticals | Vitamin b12 nasal spray and method of use |
| US20130131007A1 (en) | 2005-09-07 | 2013-05-23 | Bebaas, Inc. | Vitamin b12 compositions |
| AU2014202415B2 (en) * | 2006-06-23 | 2016-02-18 | Par Pharmaceutical, Inc | Cyanocobalamin low viscosity aqueous formulations for intranasal delivery |
| EP2035441A4 (de) * | 2006-06-23 | 2013-01-16 | Par Pharmaceutical Inc | Wässrige cyanocobalaminformulierungen mit niedriger viskosität für die intranasale verabreichung |
| JP5515198B2 (ja) * | 2007-05-09 | 2014-06-11 | 大正製薬株式会社 | メコバラミン含有粉体 |
| JP5797227B2 (ja) * | 2013-05-21 | 2015-10-21 | パル ファーマシューティカル， インコーポレーテッド | 鼻内送達用シアノコバラミン低粘度水性製剤 |
| JP6097787B2 (ja) * | 2015-06-09 | 2017-03-15 | パル ファーマシューティカル， インコーポレーテッド | 鼻内送達用シアノコバラミン低粘度水性製剤 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2746796A (en) * | 1953-08-05 | 1956-05-22 | Pharma Craft Corp | Metering valve aerosol bottle |
| US2914222A (en) * | 1957-05-20 | 1959-11-24 | Meshberg Philip | Aerosol package |
| US4525341A (en) * | 1984-04-09 | 1985-06-25 | Mayor Pharmaceutical Laboratories, Inc. | Method of administering vitamins |
-
1986
- 1986-04-02 EP EP86902640A patent/EP0218679B1/de not_active Expired - Lifetime
- 1986-04-02 WO PCT/US1986/000665 patent/WO1986005987A1/en not_active Ceased
- 1986-04-02 AT AT86902640T patent/ATE70180T1/de active
- 1986-04-02 DE DE8686902640T patent/DE3682862D1/de not_active Expired - Lifetime
- 1986-04-02 JP JP61502169A patent/JPS62500788A/ja active Pending
- 1986-04-16 CA CA000506798A patent/CA1317881C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE3682862D1 (de) | 1992-01-23 |
| EP0218679A4 (de) | 1987-10-08 |
| JPS62500788A (ja) | 1987-04-02 |
| CA1317881C (en) | 1993-05-18 |
| EP0218679B1 (de) | 1991-12-11 |
| EP0218679A1 (de) | 1987-04-22 |
| WO1986005987A1 (en) | 1986-10-23 |
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