ZA200802186B - Prion-specific peptoid reagents - Google Patents
Prion-specific peptoid reagentsInfo
- Publication number
- ZA200802186B ZA200802186B ZA200802186A ZA200802186A ZA200802186B ZA 200802186 B ZA200802186 B ZA 200802186B ZA 200802186 A ZA200802186 A ZA 200802186A ZA 200802186 A ZA200802186 A ZA 200802186A ZA 200802186 B ZA200802186 B ZA 200802186B
- Authority
- ZA
- South Africa
- Prior art keywords
- prion
- peptoid reagents
- specific
- specific peptoid
- reagents
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US71576105P | 2005-09-09 | 2005-09-09 | |
US72668605P | 2005-10-14 | 2005-10-14 | |
US75893406P | 2006-01-13 | 2006-01-13 | |
PCT/US2006/035226 WO2007030804A1 (en) | 2005-09-09 | 2006-09-08 | Prion-specific peptoid reagents |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200802186B true ZA200802186B (en) | 2008-12-31 |
Family
ID=37651167
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200802186A ZA200802186B (en) | 2005-09-09 | 2008-03-07 | Prion-specific peptoid reagents |
Country Status (14)
Country | Link |
---|---|
US (2) | US7834144B2 (da) |
EP (2) | EP1931695B1 (da) |
JP (2) | JP5209477B2 (da) |
KR (1) | KR20080048527A (da) |
CN (1) | CN101356186A (da) |
AU (1) | AU2006287299B2 (da) |
BR (1) | BRPI0615618A2 (da) |
CA (1) | CA2621767A1 (da) |
DK (1) | DK1931695T3 (da) |
ES (1) | ES2404940T3 (da) |
IL (1) | IL189992A0 (da) |
NZ (2) | NZ594844A (da) |
WO (1) | WO2007030804A1 (da) |
ZA (1) | ZA200802186B (da) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060035242A1 (en) * | 2004-08-13 | 2006-02-16 | Michelitsch Melissa D | Prion-specific peptide reagents |
WO2006076683A2 (en) * | 2005-01-13 | 2006-07-20 | Novartis Vaccines And Diagnostics Inc. | Isolation and detection of pathogenic prions |
EP1848830A4 (en) * | 2005-01-13 | 2009-05-06 | Novartis Vaccines & Diagnostic | ISOLATION OF PATHOGENIC PRIONS |
NZ594844A (en) | 2005-09-09 | 2013-04-26 | Novartis Ag | Prion-specific peptoid reagents |
FR2892820B1 (fr) * | 2005-11-03 | 2008-02-01 | Diagast Soc Par Actions Simpli | Procede magnetique d'immunodiagnostic pour la mise en evidence de complexe anticorps/antigene, en particulier de groupe sanguin |
EP2591795B1 (en) * | 2007-02-23 | 2018-02-28 | The Research Foundation Of State University Of New York | RNA targeting compounds and methods for making and using same |
US9260476B2 (en) | 2007-02-23 | 2016-02-16 | The Research Foundation For The State University Of New York | RNA targeting compounds and methods for making and using same |
CA2684796A1 (en) * | 2007-04-04 | 2008-10-16 | Novartis Ag | Prion assay |
US20100291598A1 (en) * | 2007-04-04 | 2010-11-18 | David Peretz | Prion elisa |
JP5400050B2 (ja) * | 2007-10-02 | 2014-01-29 | シーエスエル、リミテッド | 治療用抗体の精製法および使用法 |
WO2009105167A2 (en) * | 2008-02-08 | 2009-08-27 | Northwestern University | Selective poly-n-substituted glycine antibiotics |
BRPI0910550A2 (pt) * | 2008-04-30 | 2015-09-29 | Novartis Ag | ensaio para confôrmeros patogênicos |
WO2010017412A1 (en) * | 2008-08-06 | 2010-02-11 | The Regents Of The University Of California | Novel biomimetic peptoid polymers |
WO2010098843A2 (en) | 2009-02-24 | 2010-09-02 | New York University | Peptoid oligomers, pharmaceutical compositions and methods of using the same |
CN102439451B (zh) | 2009-06-02 | 2014-12-03 | 德克萨斯大学系统董事会 | 患神经退行性疾病的对象中抗体所识别的小分子的鉴定 |
JP2013510297A (ja) * | 2009-11-04 | 2013-03-21 | ノバルティス アーゲー | モノマーからのタンパク質凝集体の分離における結合試薬としての正に荷電した種 |
US8952127B2 (en) | 2010-06-04 | 2015-02-10 | The Regents Of The University Of California | Peptoids useful for catalyzing the mineralization of calcium carbonate |
WO2013043669A1 (en) * | 2011-09-21 | 2013-03-28 | The Board Of Regents Of The University Of Texas System | Peptoid compositions for the treatment of alzheimer's disease and polyglutamine expansion disorder |
US10391068B2 (en) * | 2012-08-06 | 2019-08-27 | Trustees Of Boston University | Prion protein ligands as therapeutic agents for neurodegenerative disorders |
US9764953B2 (en) | 2013-03-20 | 2017-09-19 | The Regents Of The University Of California | Peptoids useful for the mineralization of apatite |
US10081605B2 (en) | 2015-03-11 | 2018-09-25 | Lumos Pharma, Inc. | Synthesis of cyclocreatine and analogs thereof |
JP7011830B2 (ja) | 2015-10-14 | 2022-01-27 | エックス-サーマ インコーポレイテッド | 氷晶形成を低減するための組成物および方法 |
JP7026644B2 (ja) * | 2016-03-09 | 2022-02-28 | マイク-アン、エルエルシー | ペプトイド親和性リガンド |
CN110730786A (zh) * | 2017-04-12 | 2020-01-24 | 先时迈纳米生物科技股份有限公司 | 新型类肽聚合物及使用方法 |
Family Cites Families (82)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4806627A (en) | 1987-05-29 | 1989-02-21 | Research Foundation Of Mental Hygiene Inc. | Hybrid cell lines producing monoclonal antibodies dircted against scrapie-associated fibril proteins |
US6075121A (en) | 1990-05-15 | 2000-06-13 | Chiron Corporation | Modified peptide and peptide libraries with protease resistance, derivatives thereof and methods of producing and screening such |
IE66205B1 (en) * | 1990-06-14 | 1995-12-13 | Paul A Bartlett | Polypeptide analogs |
DE69132470D1 (de) * | 1990-08-06 | 2000-12-21 | Chiron Corp | Verfahren zum nachweis von cytokinkonvertasehemmern |
NZ246059A (en) | 1991-12-03 | 1995-08-28 | Proteus Molecular Design | Synthetic polypeptides with at least one antigenic site of a prion protein, methods of their use and manufacture, antibodies thereto, compositions and kits |
AU4376093A (en) | 1992-05-15 | 1993-12-13 | Instituto Nazionale Neurologico C. Besta | Soluble prion polypeptides, and methods for detecting and purifying thereof |
BR9307092A (pt) * | 1992-09-24 | 1999-03-30 | Chiron Corp | Processo para sintetizar monômero de poliamida n-substituida oligômero mistura de pelo menos dois oligômeros diferentes poli (n-substituida glicina) processo de tratamento anti-sentido composição processo de sintetizar composto de poliamida composto e processo para preparar mistura de compostos de amida |
US5877278A (en) | 1992-09-24 | 1999-03-02 | Chiron Corporation | Synthesis of N-substituted oligomers |
US5831005A (en) | 1992-09-24 | 1998-11-03 | Chiron Corporation | Synthesis of N-substituted oligomers |
US5948763A (en) * | 1995-06-07 | 1999-09-07 | New York University | Peptides and pharmaceutical compositions thereof for treatment of disorders or diseases associated with abnormal protein folding into amyloid or amyloid-like deposits |
ES2218598T3 (es) * | 1995-09-14 | 2004-11-16 | The Regents Of The University Of California | Anticuerpo especifico del prpsc natural. |
US5750361A (en) | 1995-11-02 | 1998-05-12 | The Regents Of The University Of California | Formation and use of prion protein (PRP) complexes |
US5695005A (en) | 1995-12-28 | 1997-12-09 | Chen; Chia-Hsien | Fluid dynamic crossflow cooling tower |
EP0891552B2 (en) | 1996-04-03 | 2008-12-31 | Stichting Dienst Landbouwkundig Onderzoek | Method for the detection of prion diseases |
US6586193B2 (en) | 1996-04-25 | 2003-07-01 | Genicon Sciences Corporation | Analyte assay using particulate labels |
US6251433B1 (en) | 1996-08-13 | 2001-06-26 | Chiron Corporation | Polycationic polymers |
DE69818388T2 (de) | 1997-02-06 | 2004-07-01 | Enfer Technology Ltd. | Immunoassay für spongiforme encephalopathien |
EP0861900A1 (en) * | 1997-02-21 | 1998-09-02 | Erziehungsdirektion Of The Canton Zurich | Immunological detection of prions |
US6787319B2 (en) * | 1997-04-16 | 2004-09-07 | American Home Products Corp. | β-amyloid peptide-binding proteins and polynucleotides encoding the same |
US7005295B1 (en) * | 1997-04-16 | 2006-02-28 | Wyeth | β-amyloid peptide-binding proteins and polynucleotides encoding the same |
ES2329955T3 (es) | 1997-04-28 | 2009-12-02 | Novartis Vaccines And Diagnostics, Inc. | Aparato para la sintesis de oligomeros, especialmente peptoides, con reciclado de reactivos. |
DE19741607A1 (de) | 1997-09-20 | 1999-03-25 | Prionics Ag | Synthetische Polypeptide zur Diagnose und Therapie von Prionerkrankungen |
US6165784A (en) | 1997-10-14 | 2000-12-26 | The United States Of America As Represented By The Secretary Of Agriculture | Antibodies for the detection of prion protein as an indication of transmissible spongiform encephalopathies |
CA2369172A1 (en) * | 1998-04-14 | 1999-10-21 | Sugen, Inc. | Ste20-related protein kinases |
US6211149B1 (en) * | 1998-08-03 | 2001-04-03 | The United States Of America As Represented By The Department Of Health And Human Services | Inhibitors of formation of protease resistant prion protein |
US6528269B1 (en) | 1998-06-22 | 2003-03-04 | Case Western Reserve University | Immunological agents specific for prion protein (PRP) |
FI982480A0 (fi) | 1998-11-17 | 1998-11-17 | Wallac Oy | Immunomääritys nisäkkäiden tarttuvan spongiomuotoisen aivotaudin määrittämiseksi |
AU3474100A (en) | 1999-01-25 | 2000-08-07 | Minerva Biotechnologies Corporation | Rapid and sensitive detection of aberrant protein aggregation in neurodegenerative diseases |
US6551843B1 (en) | 1999-01-29 | 2003-04-22 | Immunivest Corporation | Methods for enhancing binding interactions between members of specific binding pairs |
ES2278617T3 (es) | 1999-06-23 | 2007-08-16 | Idexx Laboratories Inc | Peptidos de proteinas de prion y sus usos. |
US6261790B1 (en) | 1999-07-15 | 2001-07-17 | The United States Of America As Represented By The Secretary Of Agriculture | Monoclonal antibodies and antibody cocktail for detection of prion protein as an indication of transmissible spongiform encephalopathies |
WO2001007479A2 (en) | 1999-07-27 | 2001-02-01 | Imperial College Innovations Limited | Fragments of cellular prion protein and methods useful in the diagnosis and treatment of prion diseases |
EP1216258A1 (en) | 1999-09-28 | 2002-06-26 | Universität Zürich | Factors having prion-binding activity in serum and plasma and agents to detect transmissible spongiform encephalopathitis |
FR2801106B1 (fr) | 1999-11-12 | 2007-10-05 | Commissariat Energie Atomique | Procede de diagnostic d'une esst provoquee par une souche d'atnc dans un echantillon biologique et son utilisation dans le diagnostic differentiel des differentes souches d'atnc |
WO2001060837A2 (en) * | 2000-02-16 | 2001-08-23 | Northwestern University | Polypeptoid pulmonary surfactants |
WO2001077687A2 (en) | 2000-04-05 | 2001-10-18 | V.I Technologies, Inc. | Prion-binding peptidic ligands and methods of using same |
IL148202A0 (en) | 2000-06-20 | 2002-09-12 | Caprion Pharmaceuticals Inc | Copolymers and methods of treating prion-related diseases |
IL153824A0 (en) | 2000-07-07 | 2003-07-31 | Applied Research Systems | Method and kit for diagnosis of diseases |
US6537548B1 (en) | 2000-07-27 | 2003-03-25 | The Regents Of The University Of California | Antibodies specific for ungulate PrP |
US20030092613A1 (en) | 2000-08-14 | 2003-05-15 | Lee Daniel H. S. | Alpha7 nicotinic receptor peptides as ligands for beta amyloid peptides |
JP2005502309A (ja) | 2000-12-23 | 2005-01-27 | カイロン コーポレイション | オリゴヌクレオチドトランスフェクションスクリーニング方法 |
GB0103508D0 (en) | 2001-02-13 | 2001-03-28 | Univ Dundee | Screening method and agents |
US20050026165A1 (en) | 2001-05-31 | 2005-02-03 | Cindy Orser | Detection of conformationally altered proteins and prions |
JP4235544B2 (ja) | 2001-05-31 | 2009-03-11 | アドライフ インコーポレーティッド | 欠陥折畳み蛋白質センサー方法 |
CN100579332C (zh) | 2001-07-19 | 2010-01-06 | 东丽株式会社 | 电路基板、电路基板用构件及其制造方法和柔性薄膜的层压方法 |
CA2466841A1 (en) * | 2001-11-21 | 2003-06-05 | New York University | Synthetic immunogenic but non-deposit-forming polypeptides and peptides homologous to amyloid .beta., prion protein, amylin, .alpha.-synuclein, or polyglutamine repeats for induction of an immune response thereto |
EP1481001A2 (en) | 2001-12-10 | 2004-12-01 | Applied Research Systems ARS Holding N.V. | Prion inhibiting peptides and derivatives thereof |
US20040052928A1 (en) * | 2002-09-06 | 2004-03-18 | Ehud Gazit | Peptides and methods using same for diagnosing and treating amyloid-associated diseases |
AU2003219730A1 (en) * | 2002-02-07 | 2003-09-02 | Massachusetts Institute Of Technology | Anti-pathogen treatements |
CA2477569C (en) | 2002-02-28 | 2013-09-24 | Microsens Biophage Limited | Selective binding of pathological forms of prion proteins using polyionic polymers |
WO2003085086A2 (en) * | 2002-04-09 | 2003-10-16 | The Scripps Research Institute | Motif-grafted hybrid polypeptides and uses thereof |
US20040208919A1 (en) * | 2002-06-13 | 2004-10-21 | Nicolau Yves C. | Vaccination against prion diseases |
DE10230141B4 (de) * | 2002-07-04 | 2004-07-15 | Priontype Gmbh | Verfahren und Kit zur Anreicherung und zum Nachweis von veränderten Prion-Proteinen (PrPSc) |
EP1382971A1 (en) | 2002-07-17 | 2004-01-21 | Pepscan Systems B.V. | Detection of prion disease |
WO2004018511A2 (en) | 2002-08-23 | 2004-03-04 | Copenhagen Biotech Assets Aps | Composite peptide compounds for diagnosis and treatment of diseases caused by prion proteins |
US20040072236A1 (en) | 2002-09-27 | 2004-04-15 | Neil Cashman | PrPSc -interacting molecules and uses thereof |
AU2003265504A1 (en) | 2002-10-10 | 2004-05-04 | Heinrich Heine University Of Dusseldorf | Use of monoclonal antibodies to distinguish protein conformational isoforms |
DK1554305T3 (da) | 2002-10-23 | 2007-04-23 | Ct For Res And Technology Hell | Prionprotein-bindende peptidsekvenser |
WO2004046728A1 (en) | 2002-11-18 | 2004-06-03 | Prionics Ag | Method for the detection of prpsc |
EP1573323B1 (en) * | 2002-12-03 | 2011-10-19 | Pathogen Removal and Diagnostic Technologies, Inc. | Prion protein ligands and methods of use |
EP1457500A1 (en) | 2003-03-14 | 2004-09-15 | University of Zurich | Soluble hybrid prion proteins and their use in the diagnosis, prevention and treatment of transmissible spongiform encephalophathies |
PT1615992E (pt) | 2003-04-04 | 2013-11-29 | Pathogen Removal & Diagnostic Technologies Inc | Materiais de ligação à proteína prião e métodos de utilização |
US7745569B2 (en) * | 2003-04-07 | 2010-06-29 | The Regents Of The University Of California | Amyloid specific binding peptides and detecting abeta peptide |
WO2004091523A2 (en) | 2003-04-14 | 2004-10-28 | American National Red Cross | Method for identifying ligands specific for structural isoforms of proteins |
US20060035242A1 (en) * | 2004-08-13 | 2006-02-16 | Michelitsch Melissa D | Prion-specific peptide reagents |
CA2535261C (en) * | 2003-08-13 | 2015-11-24 | Chiron Corporation | Prion-specific peptide reagents |
JP3910569B2 (ja) | 2003-08-19 | 2007-04-25 | 独立行政法人科学技術振興機構 | アミロイドβ蛋白質のアミロイド線維化を増幅するための試薬 |
CA2549720C (en) | 2003-12-19 | 2013-10-15 | Chiron Corporation | Cell transfecting formulations of small interfering rna, related compositions and methods of making and use |
SE0400274D0 (sv) | 2004-02-09 | 2004-02-09 | Affibody Ab | New polypeptide |
JP4773697B2 (ja) | 2004-06-30 | 2011-09-14 | ルネサスエレクトロニクス株式会社 | Soi基板およびその製造方法ならびに半導体装置 |
DE102004043782A1 (de) | 2004-09-08 | 2006-03-09 | Heinrich-Heine-Universität Düsseldorf | Polypeptide und Verfahren zur spezifischen Bindung von Prionen |
US20060057671A1 (en) * | 2004-09-10 | 2006-03-16 | Orser Cindy S | Immobilized probes and methods of detecting conformationally altered prion proteins |
US7482172B2 (en) * | 2005-09-19 | 2009-01-27 | Ortho-Clinical Diagnostics, Inc. | Peptides for discrimination of prions |
AU2005209592B2 (en) | 2004-09-30 | 2012-07-12 | Ortho-Clinical Diagnostics, Inc. | Peptides for discrimination of prions |
MX2007008497A (es) | 2005-01-13 | 2007-09-14 | Novartis Vaccines & Diagnostic | Ensayos inmunosorbentes enlazados a enzimas usando reactivos de peptidos especificos de prion. |
EP1848830A4 (en) | 2005-01-13 | 2009-05-06 | Novartis Vaccines & Diagnostic | ISOLATION OF PATHOGENIC PRIONS |
AU2006214463B2 (en) | 2005-02-15 | 2012-08-30 | Presympto, Inc. | Method for detecting misfolded proteins and prions |
GB0503434D0 (en) | 2005-02-18 | 2005-03-30 | Senexis Ltd | Amyloid-binding peptides, analogues and uses thereof |
NZ594844A (en) | 2005-09-09 | 2013-04-26 | Novartis Ag | Prion-specific peptoid reagents |
WO2007145589A1 (en) | 2006-06-15 | 2007-12-21 | Per Arvidsson | Peptides that are capable of binding to amyloid-beta peptide. |
CN101802609A (zh) | 2006-07-28 | 2010-08-11 | 阿德利夫股份有限公司 | 用于诊断和治疗的肽探针 |
US9217036B2 (en) | 2007-04-26 | 2015-12-22 | Yale University | Prion protein as a receptor for amyloid-β oligomers |
-
2006
- 2006-09-08 NZ NZ594844A patent/NZ594844A/xx not_active IP Right Cessation
- 2006-09-08 AU AU2006287299A patent/AU2006287299B2/en not_active Ceased
- 2006-09-08 EP EP06814415.3A patent/EP1931695B1/en not_active Not-in-force
- 2006-09-08 JP JP2008530008A patent/JP5209477B2/ja not_active Expired - Fee Related
- 2006-09-08 DK DK06814415.3T patent/DK1931695T3/da active
- 2006-09-08 WO PCT/US2006/035226 patent/WO2007030804A1/en active Application Filing
- 2006-09-08 NZ NZ566020A patent/NZ566020A/xx not_active IP Right Cessation
- 2006-09-08 US US11/518,091 patent/US7834144B2/en not_active Expired - Fee Related
- 2006-09-08 EP EP20110171585 patent/EP2383281A3/en not_active Withdrawn
- 2006-09-08 CN CNA2006800331296A patent/CN101356186A/zh active Pending
- 2006-09-08 ES ES06814415T patent/ES2404940T3/es active Active
- 2006-09-08 KR KR1020087008427A patent/KR20080048527A/ko active IP Right Grant
- 2006-09-08 CA CA002621767A patent/CA2621767A1/en not_active Abandoned
- 2006-09-08 BR BRPI0615618-5A patent/BRPI0615618A2/pt not_active IP Right Cessation
-
2008
- 2008-03-06 IL IL189992A patent/IL189992A0/en unknown
- 2008-03-07 ZA ZA200802186A patent/ZA200802186B/xx unknown
-
2010
- 2010-10-07 US US12/924,872 patent/US20120027677A1/en not_active Abandoned
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2012
- 2012-06-01 JP JP2012126346A patent/JP2012162571A/ja not_active Withdrawn
Also Published As
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JP2009507833A (ja) | 2009-02-26 |
KR20080048527A (ko) | 2008-06-02 |
EP1931695B1 (en) | 2013-04-10 |
US20070087972A1 (en) | 2007-04-19 |
CN101356186A (zh) | 2009-01-28 |
DK1931695T3 (da) | 2013-07-01 |
EP2383281A3 (en) | 2012-01-04 |
AU2006287299B2 (en) | 2012-08-23 |
IL189992A0 (en) | 2008-08-07 |
CA2621767A1 (en) | 2007-03-15 |
JP5209477B2 (ja) | 2013-06-12 |
NZ566020A (en) | 2012-08-31 |
EP2383281A2 (en) | 2011-11-02 |
US20120027677A1 (en) | 2012-02-02 |
AU2006287299A1 (en) | 2007-03-15 |
WO2007030804A1 (en) | 2007-03-15 |
US7834144B2 (en) | 2010-11-16 |
NZ594844A (en) | 2013-04-26 |
JP2012162571A (ja) | 2012-08-30 |
ES2404940T3 (es) | 2013-05-29 |
EP1931695A1 (en) | 2008-06-18 |
BRPI0615618A2 (pt) | 2011-05-24 |
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