ZA200710662B - 1-[2', 3'-dideoxy-3' C-(hydroxymethyl)-beta-d-erythropentofuranosyl] cytosine derivatives as HIV inhibitors - Google Patents

1-[2', 3'-dideoxy-3' C-(hydroxymethyl)-beta-d-erythropentofuranosyl] cytosine derivatives as HIV inhibitors

Info

Publication number
ZA200710662B
ZA200710662B ZA200710662A ZA200710662A ZA200710662B ZA 200710662 B ZA200710662 B ZA 200710662B ZA 200710662 A ZA200710662 A ZA 200710662A ZA 200710662 A ZA200710662 A ZA 200710662A ZA 200710662 B ZA200710662 B ZA 200710662B
Authority
ZA
South Africa
Prior art keywords
erythropentofuranosyl
dideoxy
hydroxymethyl
beta
hiv inhibitors
Prior art date
Application number
ZA200710662A
Other languages
English (en)
Inventor
Zhou Ziao-Xiong
Sahlberg Christer
Original Assignee
Medivir Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medivir Ab filed Critical Medivir Ab
Publication of ZA200710662B publication Critical patent/ZA200710662B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA200710662A 2005-07-07 2007-12-06 1-[2', 3'-dideoxy-3' C-(hydroxymethyl)-beta-d-erythropentofuranosyl] cytosine derivatives as HIV inhibitors ZA200710662B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0513835.9A GB0513835D0 (en) 2005-07-07 2005-07-07 HIV inhibitors

Publications (1)

Publication Number Publication Date
ZA200710662B true ZA200710662B (en) 2008-11-26

Family

ID=34856749

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200710662A ZA200710662B (en) 2005-07-07 2007-12-06 1-[2', 3'-dideoxy-3' C-(hydroxymethyl)-beta-d-erythropentofuranosyl] cytosine derivatives as HIV inhibitors

Country Status (19)

Country Link
US (2) US7888367B2 (pt)
EP (2) EP1899352B1 (pt)
JP (1) JP5174660B2 (pt)
CN (1) CN101213198B (pt)
AT (1) ATE527267T1 (pt)
AU (1) AU2006268743C1 (pt)
BR (1) BRPI0612678A2 (pt)
CA (1) CA2610210A1 (pt)
CY (1) CY1112164T1 (pt)
DK (1) DK1899352T3 (pt)
ES (1) ES2373743T3 (pt)
GB (1) GB0513835D0 (pt)
HK (1) HK1122798A1 (pt)
HR (1) HRP20110830T1 (pt)
MX (1) MX2008000221A (pt)
PL (1) PL1899352T3 (pt)
PT (1) PT1899352E (pt)
WO (1) WO2007006707A1 (pt)
ZA (1) ZA200710662B (pt)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8810907D0 (en) 1988-05-09 1988-06-15 British Telecomm Fluoride glass optical coupler & method of manufacture
ZA902631B (en) * 1989-04-06 1990-12-28 Bristol Myers Squibb Co 3'-substituted methyl nucleosides as antiviral agents
US5866775A (en) 1990-09-28 1999-02-02 Monsanto Company Glyphosate-tolerant 5-enolpyruvyl-3-phosphoshikimate synthases
US5627160A (en) * 1993-05-25 1997-05-06 Yale University L-2',3'-dideoxy nucleoside analogs as anti-hepatitis B (HBV) and anti-HIV agents
JPH10501217A (ja) * 1994-05-31 1998-02-03 メディヴィル・アクチボラグ Ｈｉｖの被爆後阻止
US5612319A (en) 1994-05-31 1997-03-18 Medivir Ab Postexposure prevention of HIV infection or seroconversion
TR200000398T2 (tr) 1997-08-15 2000-07-21 Medivir Ab Hepatit B virüsü (HBV) retroviral ters transkriptaz ve DNA polimeraz inhibe edicilerini içeren antiviraller gibi nükleozidlerin analogları.
DE60136620D1 (de) * 2000-04-13 2009-01-02 Pharmasset Inc 3 oder 2 hydroxymethyl substituierte nucleoside derivate und ihre verwendung zur behandlung von virusinfektionen
US7109931B2 (en) 2004-06-18 2006-09-19 Centurion Wireless Technologies, Inc. Method and apparatus to control an antenna efficiency test device
EA011039B1 (ru) * 2004-12-30 2008-12-30 Медивир Аб Приемлемые для лечения вич соединения

Also Published As

Publication number Publication date
EP1899352A1 (en) 2008-03-19
JP5174660B2 (ja) 2013-04-03
CA2610210A1 (en) 2007-01-18
CY1112164T1 (el) 2015-12-09
MX2008000221A (es) 2008-03-18
GB0513835D0 (en) 2005-08-10
ATE527267T1 (de) 2011-10-15
US20080221140A1 (en) 2008-09-11
DK1899352T3 (da) 2012-01-30
PT1899352E (pt) 2012-01-05
US20110112294A1 (en) 2011-05-12
CN101213198A (zh) 2008-07-02
BRPI0612678A2 (pt) 2010-11-30
US7888367B2 (en) 2011-02-15
HRP20110830T1 (hr) 2011-12-31
WO2007006707A1 (en) 2007-01-18
US8143396B2 (en) 2012-03-27
EP1899352B1 (en) 2011-10-05
EP2336135A2 (en) 2011-06-22
EP2336135A3 (en) 2011-07-27
PL1899352T3 (pl) 2012-03-30
JP2008545002A (ja) 2008-12-11
CN101213198B (zh) 2011-08-03
AU2006268743B2 (en) 2010-07-29
HK1122798A1 (en) 2009-05-29
AU2006268743A1 (en) 2007-01-18
AU2006268743C1 (en) 2010-12-16
ES2373743T3 (es) 2012-02-08

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ZA200710662B (en) 1-[2', 3'-dideoxy-3' C-(hydroxymethyl)-beta-d-erythropentofuranosyl] cytosine derivatives as HIV inhibitors