ZA200705223B - Monoclonal and polyclonal antibodies to equine hemoglobin and apparatus and methods using the antibodies and/or peroxidase reactions in the identification and localization of ulcers in equines - Google Patents
Monoclonal and polyclonal antibodies to equine hemoglobin and apparatus and methods using the antibodies and/or peroxidase reactions in the identification and localization of ulcers in equines Download PDFInfo
- Publication number
- ZA200705223B ZA200705223B ZA200705223A ZA200705223A ZA200705223B ZA 200705223 B ZA200705223 B ZA 200705223B ZA 200705223 A ZA200705223 A ZA 200705223A ZA 200705223 A ZA200705223 A ZA 200705223A ZA 200705223 B ZA200705223 B ZA 200705223B
- Authority
- ZA
- South Africa
- Prior art keywords
- equine
- antibody
- test kit
- hematin
- test
- Prior art date
Links
- 241000283073 Equus caballus Species 0.000 title claims description 132
- 208000025865 Ulcer Diseases 0.000 title claims description 65
- 231100000397 ulcer Toxicity 0.000 title claims description 64
- 238000000034 method Methods 0.000 title claims description 44
- 238000006243 chemical reaction Methods 0.000 title claims description 11
- 102000003992 Peroxidases Human genes 0.000 title claims description 6
- 108040007629 peroxidase activity proteins Proteins 0.000 title claims description 6
- 230000004807 localization Effects 0.000 title claims description 5
- 102000001554 Hemoglobins Human genes 0.000 title description 3
- 108010054147 Hemoglobins Proteins 0.000 title description 3
- 238000012360 testing method Methods 0.000 claims description 185
- 208000007107 Stomach Ulcer Diseases 0.000 claims description 43
- 206010023799 Large intestinal ulcer Diseases 0.000 claims description 41
- BMUDPLZKKRQECS-UHFFFAOYSA-K 3-[18-(2-carboxyethyl)-8,13-bis(ethenyl)-3,7,12,17-tetramethylporphyrin-21,24-diid-2-yl]propanoic acid iron(3+) hydroxide Chemical compound [OH-].[Fe+3].[N-]1C2=C(C)C(CCC(O)=O)=C1C=C([N-]1)C(CCC(O)=O)=C(C)C1=CC(C(C)=C1C=C)=NC1=CC(C(C)=C1C=C)=NC1=C2 BMUDPLZKKRQECS-UHFFFAOYSA-K 0.000 claims description 40
- 229940109738 hematin Drugs 0.000 claims description 40
- 102000018146 globin Human genes 0.000 claims description 35
- 108060003196 globin Proteins 0.000 claims description 35
- 210000001035 gastrointestinal tract Anatomy 0.000 claims description 21
- 201000005917 gastric ulcer Diseases 0.000 claims description 18
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/721—Haemoglobin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/11—Immunoglobulins specific features characterized by their source of isolation or production isolated from eggs
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/06—Gastro-intestinal diseases
- G01N2800/062—Gastritis or peptic ulcer disease
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Food Science & Technology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63316704P | 2004-12-04 | 2004-12-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200705223B true ZA200705223B (en) | 2008-05-28 |
Family
ID=35998454
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200705223A ZA200705223B (en) | 2004-12-04 | 2007-07-02 | Monoclonal and polyclonal antibodies to equine hemoglobin and apparatus and methods using the antibodies and/or peroxidase reactions in the identification and localization of ulcers in equines |
Country Status (10)
Country | Link |
---|---|
US (1) | US20060134707A1 (fr) |
EP (1) | EP1831255A1 (fr) |
JP (1) | JP2008522196A (fr) |
CN (1) | CN101072796A (fr) |
AU (1) | AU2005314324A1 (fr) |
BR (1) | BRPI0519060A2 (fr) |
CA (1) | CA2589759A1 (fr) |
MX (1) | MX2007006621A (fr) |
WO (1) | WO2006062800A1 (fr) |
ZA (1) | ZA200705223B (fr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7629180B2 (en) | 2004-12-04 | 2009-12-08 | Freedom Health, Llc | Test kit for the rapid detection and localization of digestive tract bleeding in equines |
CA2578313A1 (fr) * | 2007-03-01 | 2007-05-14 | Biolytical Laboratories Inc. | Dispositif de dosage immunologique parallele rapide et tres precis |
US8053203B2 (en) * | 2007-10-30 | 2011-11-08 | John Wan | Methods and device for the detection of occult blood |
CN102914538B (zh) * | 2012-10-30 | 2014-06-11 | 青岛贝尔奥生物科技有限公司 | 一种检测直肠渗液血红素的方法 |
CN102928424B (zh) * | 2012-10-30 | 2014-06-11 | 青岛贝尔奥生物科技有限公司 | 一种检测宫颈渗液血红素的方法 |
WO2014094338A1 (fr) * | 2012-12-17 | 2014-06-26 | 青岛贝尔奥生物科技有限公司 | Procédé et boitier de détection permettant de détecter un hème libre d'exsudat de rhinopharynx |
CN103033509B (zh) * | 2013-01-06 | 2014-11-12 | 青岛贝尔奥生物科技有限公司 | 一种检测前列腺液游离血红素的方法 |
US9903858B2 (en) * | 2014-07-23 | 2018-02-27 | Ortho-Clinical Diagnostics, Inc. | Multiplexing with single sample metering event to increase throughput |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4260393A (en) * | 1979-01-15 | 1981-04-07 | Technology Resources, Inc. | Method and combined test elements for detection of heme |
US4675160A (en) * | 1986-01-28 | 1987-06-23 | Warner-Lambert Company | Occult blood test monitor |
US5198365A (en) * | 1987-02-04 | 1993-03-30 | International Immunoassay Laboratories, Inc. | Fecal sample immunoassay method testing for hemoglobin |
EP0281251A3 (fr) * | 1987-02-04 | 1988-09-28 | International Immunoassay Laboratories, Inc. | Procédé pour préparer une composition d'un échantillon fécal pour vérification par essai immunologique |
US4806468A (en) * | 1987-02-05 | 1989-02-21 | Becton, Dickinson And Company | Measurement of glycosylated hemoglobin by immunoassay |
US5081040A (en) * | 1987-06-29 | 1992-01-14 | Helena Laboratories Corporation | Composition and kit for testing for occult blood in human and animal excretions, fluids, or tissue matrixes |
US5064766A (en) * | 1989-10-18 | 1991-11-12 | Wardlaw Stephen C | Method for differentiating the source of occult gastrointestinal bleeding |
US5141850A (en) * | 1990-02-07 | 1992-08-25 | Hygeia Sciences, Inc. | Porous strip form assay device method |
FI92882C (fi) * | 1992-12-29 | 1995-01-10 | Medix Biochemica Ab Oy | Kertakäyttöinen testiliuska ja menetelmä sen valmistamiseksi |
US5460969A (en) * | 1993-03-15 | 1995-10-24 | Fielder; Paul N. | Method for differentiating the source of occult gastrointestinal bleeding |
US5552295A (en) * | 1994-03-02 | 1996-09-03 | The United States Of America As Represented By The Secretary Of Agriculture | Monoclonal antibodies to bovine haptoglobin and methods for detecting serum haptoglobin levels |
US20010051350A1 (en) * | 1995-05-02 | 2001-12-13 | Albert Nazareth | Diagnostic detection device and method |
AUPP713498A0 (en) * | 1998-11-17 | 1998-12-10 | Chandler, Howard Milne | A method of detecting blood |
US6844195B2 (en) * | 2000-12-01 | 2005-01-18 | Western Research Company | Method for determining location of gastrointestinal bleeding |
US7067264B2 (en) * | 2001-07-23 | 2006-06-27 | Bagaria Padma S | Test device for detecting human blood and method of use |
-
2005
- 2005-12-01 CA CA002589759A patent/CA2589759A1/fr not_active Abandoned
- 2005-12-01 BR BRPI0519060-6A patent/BRPI0519060A2/pt not_active Application Discontinuation
- 2005-12-01 JP JP2007544501A patent/JP2008522196A/ja active Pending
- 2005-12-01 MX MX2007006621A patent/MX2007006621A/es not_active Application Discontinuation
- 2005-12-01 EP EP05852614A patent/EP1831255A1/fr not_active Withdrawn
- 2005-12-01 US US11/291,696 patent/US20060134707A1/en not_active Abandoned
- 2005-12-01 AU AU2005314324A patent/AU2005314324A1/en not_active Abandoned
- 2005-12-01 WO PCT/US2005/043430 patent/WO2006062800A1/fr active Application Filing
- 2005-12-01 CN CNA200580041509XA patent/CN101072796A/zh active Pending
-
2007
- 2007-07-02 ZA ZA200705223A patent/ZA200705223B/en unknown
Also Published As
Publication number | Publication date |
---|---|
MX2007006621A (es) | 2008-02-21 |
CA2589759A1 (fr) | 2006-06-15 |
CN101072796A (zh) | 2007-11-14 |
AU2005314324A1 (en) | 2006-06-15 |
AU2005314324A2 (en) | 2006-06-15 |
US20060134707A1 (en) | 2006-06-22 |
EP1831255A1 (fr) | 2007-09-12 |
BRPI0519060A2 (pt) | 2009-01-13 |
JP2008522196A (ja) | 2008-06-26 |
WO2006062800A1 (fr) | 2006-06-15 |
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